SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '9YM'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K6C_B_MK1B902_1
(POL POLYPROTEIN)		 5w70 L-GLUTAMINE:2-DEOXY-
SCYLLO-INOSOSE
AMINOTRANSFERASE
(Streptomyces
ribosidificus) 		5 / 10 ASP A 173
ALA A 175
GLY A 209
GLY A 210
THR A 108
 9YM  A 501 (-2.9A)
9YM  A 501 (-3.4A)
None
None
None
 1.01A 1k6cA-5w70A:
undetectable		 1k6cA-5w70A:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLA_A_CHDA501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5w70 L-GLUTAMINE:2-DEOXY-
SCYLLO-INOSOSE
AMINOTRANSFERASE
(Streptomyces
ribosidificus) 		4 / 7 ARG A 360
SER A 197
VAL A 103
TRP A 102
 None
9YM  A 501 (-2.5A)
None
9YM  A 501 (-3.6A)
 1.49A 4klaA-5w70A:
undetectable		 4klaA-5w70A:
20.00