SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '9XG'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		 5w88 TROPONIN C, TROPONIN
I
(Homo
sapiens) 		7 / 11 PHE A  27
ILE A  36
LEU A  41
MET A  45
LEU A  48
MET A  60
VAL A  64
 9XG  A 201 (-3.8A)
9XG  A 201 ( 3.3A)
9XG  A 201 (-3.9A)
9XG  A 201 (-2.4A)
9XG  A 201 ( 4.8A)
9XG  A 201 (-4.0A)
None
 0.78A 1dtlA-5w88A:
10.7		 1dtlA-5w88A:
65.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		 5w88 TROPONIN C, TROPONIN
I
(Homo
sapiens) 		5 / 12 ALA A  23
ILE A  26
PHE A  77
MET A  81
LEU A  48
 None
None
9XG  A 201 (-3.8A)
9XG  A 201 ( 4.6A)
9XG  A 201 ( 4.8A)
 1.19A 1dtlA-5w88A:
10.7		 1dtlA-5w88A:
65.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DTL_A_BEPA206_1
(CARDIAC TROPONIN C)		 5w88 TROPONIN C, TROPONIN
I
(Homo
sapiens) 		4 / 8 MET A  45
GLN A  50
PRO A  52
GLU A  56
 9XG  A 201 (-2.4A)
None
None
None
 0.53A 1dtlA-5w88A:
10.7		 1dtlA-5w88A:
65.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 5w88 TROPONIN C, TROPONIN
I
(Homo
sapiens) 		9 / 12 PHE A  27
ILE A  36
LEU A  41
MET A  45
LEU A  48
MET A  60
ILE A  61
GLU A  63
VAL A  72
 9XG  A 201 (-3.8A)
9XG  A 201 ( 3.3A)
9XG  A 201 (-3.9A)
9XG  A 201 (-2.4A)
9XG  A 201 ( 4.8A)
9XG  A 201 (-4.0A)
9XG  A 201 ( 4.0A)
None
9XG  A 201 (-3.8A)
 0.84A 1lxfC-5w88A:
9.8		 1lxfC-5w88A:
97.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 5w88 TROPONIN C, TROPONIN
I
(Homo
sapiens) 		6 / 12 PHE A  27
LEU A  41
MET A  45
LEU A  48
GLU A  63
MET A  80
 9XG  A 201 (-3.8A)
9XG  A 201 (-3.9A)
9XG  A 201 (-2.4A)
9XG  A 201 ( 4.8A)
None
9XG  A 201 (-4.0A)
 1.00A 1lxfC-5w88A:
9.8		 1lxfC-5w88A:
97.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1WRK_A_TFPA202_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 5w88 TROPONIN C, TROPONIN
I
(Homo
sapiens) 		6 / 10 MET A  45
LEU A  48
GLN A  50
GLU A  56
MET A  60
MET A  81
 9XG  A 201 (-2.4A)
9XG  A 201 ( 4.8A)
None
None
9XG  A 201 (-4.0A)
9XG  A 201 ( 4.6A)
 0.99A 1wrkA-5w88A:
11.9
1wrkB-5w88A:
11.5		 1wrkA-5w88A:
100.00
1wrkB-5w88A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1WRK_A_TFPA204_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 5w88 TROPONIN C, TROPONIN
I
(Homo
sapiens) 		6 / 9 PHE A  20
PHE A  27
LEU A  48
MET A  81
SER A  84
LEU A 157
 None
9XG  A 201 (-3.8A)
9XG  A 201 ( 4.8A)
9XG  A 201 ( 4.6A)
9XG  A 201 ( 4.3A)
None
 1.39A 1wrkA-5w88A:
11.9
1wrkB-5w88A:
11.5		 1wrkA-5w88A:
100.00
1wrkB-5w88A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1WRK_A_TFPA204_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 5w88 TROPONIN C, TROPONIN
I
(Homo
sapiens) 		7 / 9 PHE A  20
PHE A  27
VAL A  44
LEU A  48
PHE A  77
MET A  81
SER A  84
 None
9XG  A 201 (-3.8A)
9XG  A 201 ( 4.2A)
9XG  A 201 ( 4.8A)
9XG  A 201 (-3.8A)
9XG  A 201 ( 4.6A)
9XG  A 201 ( 4.3A)
 1.33A 1wrkA-5w88A:
11.9
1wrkB-5w88A:
11.5		 1wrkA-5w88A:
100.00
1wrkB-5w88A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1WRK_B_TFPB201_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 5w88 TROPONIN C, TROPONIN
I
(Homo
sapiens) 		5 / 10 MET A  45
LEU A  48
GLN A  50
MET A  60
MET A  81
 9XG  A 201 (-2.4A)
9XG  A 201 ( 4.8A)
None
9XG  A 201 (-4.0A)
9XG  A 201 ( 4.6A)
 1.12A 1wrkA-5w88A:
11.9
1wrkB-5w88A:
11.5		 1wrkA-5w88A:
100.00
1wrkB-5w88A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1WRK_B_TFPB203_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 5w88 TROPONIN C, TROPONIN
I
(Homo
sapiens) 		4 / 5 PHE A  27
LEU A  48
PHE A  77
MET A  81
 9XG  A 201 (-3.8A)
9XG  A 201 ( 4.8A)
9XG  A 201 (-3.8A)
9XG  A 201 ( 4.6A)
 1.17A 1wrkB-5w88A:
11.5		 1wrkB-5w88A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1WRL_A_TFPA204_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 5w88 TROPONIN C, TROPONIN
I
(Homo
sapiens) 		5 / 7 PHE A  27
LEU A  48
PHE A  77
MET A  81
VAL A  82
 9XG  A 201 (-3.8A)
9XG  A 201 ( 4.8A)
9XG  A 201 (-3.8A)
9XG  A 201 ( 4.6A)
None
 1.23A 1wrlA-5w88A:
11.9
1wrlB-5w88A:
12.2		 1wrlA-5w88A:
100.00
1wrlB-5w88A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1WRL_A_TFPA204_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 5w88 TROPONIN C, TROPONIN
I
(Homo
sapiens) 		4 / 7 PHE A  77
MET A  81
VAL A  82
SER A  84
 9XG  A 201 (-3.8A)
9XG  A 201 ( 4.6A)
None
9XG  A 201 ( 4.3A)
 0.98A 1wrlA-5w88A:
11.9
1wrlB-5w88A:
12.2		 1wrlA-5w88A:
100.00
1wrlB-5w88A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1WRL_B_TFPB201_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 5w88 TROPONIN C, TROPONIN
I
(Homo
sapiens) 		6 / 9 MET A  45
LEU A  48
GLN A  50
GLU A  56
MET A  60
MET A  81
 9XG  A 201 (-2.4A)
9XG  A 201 ( 4.8A)
None
None
9XG  A 201 (-4.0A)
9XG  A 201 ( 4.6A)
 1.07A 1wrlA-5w88A:
11.9
1wrlB-5w88A:
12.2		 1wrlA-5w88A:
100.00
1wrlB-5w88A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1WRL_B_TFPB203_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 5w88 TROPONIN C, TROPONIN
I
(Homo
sapiens) 		5 / 6 PHE A  27
VAL A  44
LEU A  48
PHE A  77
MET A  81
 9XG  A 201 (-3.8A)
9XG  A 201 ( 4.2A)
9XG  A 201 ( 4.8A)
9XG  A 201 (-3.8A)
9XG  A 201 ( 4.6A)
 1.36A 1wrlB-5w88A:
12.2		 1wrlB-5w88A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1WRL_B_TFPB203_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 5w88 TROPONIN C, TROPONIN
I
(Homo
sapiens) 		5 / 6 PHE A  27
VAL A  44
PHE A  77
MET A  81
SER A  84
 9XG  A 201 (-3.8A)
9XG  A 201 ( 4.2A)
9XG  A 201 (-3.8A)
9XG  A 201 ( 4.6A)
9XG  A 201 ( 4.3A)
 1.48A 1wrlB-5w88A:
12.2		 1wrlB-5w88A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1WRL_C_TFPC206_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 5w88 TROPONIN C, TROPONIN
I
(Homo
sapiens) 		6 / 9 MET A  45
LEU A  48
GLN A  50
GLU A  56
MET A  60
MET A  81
 9XG  A 201 (-2.4A)
9XG  A 201 ( 4.8A)
None
None
9XG  A 201 (-4.0A)
9XG  A 201 ( 4.6A)
 0.97A 1wrlC-5w88A:
12.0
1wrlD-5w88A:
11.4		 1wrlC-5w88A:
100.00
1wrlD-5w88A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1WRL_C_TFPC208_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 5w88 TROPONIN C, TROPONIN
I
(Homo
sapiens) 		4 / 5 PHE A  27
LEU A  48
PHE A  77
MET A  81
 9XG  A 201 (-3.8A)
9XG  A 201 ( 4.8A)
9XG  A 201 (-3.8A)
9XG  A 201 ( 4.6A)
 1.20A 1wrlC-5w88A:
12.0		 1wrlC-5w88A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1WRL_D_TFPD205_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 5w88 TROPONIN C, TROPONIN
I
(Homo
sapiens) 		5 / 10 MET A  45
LEU A  48
GLN A  50
MET A  60
MET A  81
 9XG  A 201 (-2.4A)
9XG  A 201 ( 4.8A)
None
9XG  A 201 (-4.0A)
9XG  A 201 ( 4.6A)
 1.06A 1wrlC-5w88A:
12.0
1wrlD-5w88A:
11.4		 1wrlC-5w88A:
100.00
1wrlD-5w88A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1WRL_D_TFPD205_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 5w88 TROPONIN C, TROPONIN
I
(Homo
sapiens) 		5 / 10 MET A  45
LEU A  48
GLU A  56
MET A  60
MET A  81
 9XG  A 201 (-2.4A)
9XG  A 201 ( 4.8A)
None
9XG  A 201 (-4.0A)
9XG  A 201 ( 4.6A)
 1.03A 1wrlC-5w88A:
12.0
1wrlD-5w88A:
11.4		 1wrlC-5w88A:
100.00
1wrlD-5w88A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1WRL_E_TFPE210_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 5w88 TROPONIN C, TROPONIN
I
(Homo
sapiens) 		5 / 9 MET A  45
LEU A  48
GLN A  50
GLU A  56
MET A  60
 9XG  A 201 (-2.4A)
9XG  A 201 ( 4.8A)
None
None
9XG  A 201 (-4.0A)
 0.90A 1wrlE-5w88A:
11.8
1wrlF-5w88A:
11.2		 1wrlE-5w88A:
100.00
1wrlF-5w88A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1WRL_E_TFPE212_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 5w88 TROPONIN C, TROPONIN
I
(Homo
sapiens) 		5 / 7 PHE A  20
PHE A  27
LEU A  48
PHE A  77
MET A  81
 None
9XG  A 201 (-3.8A)
9XG  A 201 ( 4.8A)
9XG  A 201 (-3.8A)
9XG  A 201 ( 4.6A)
 1.26A 1wrlE-5w88A:
11.8		 1wrlE-5w88A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1WRL_E_TFPE212_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 5w88 TROPONIN C, TROPONIN
I
(Homo
sapiens) 		4 / 7 PHE A  20
PHE A  77
MET A  81
SER A  84
 None
9XG  A 201 (-3.8A)
9XG  A 201 ( 4.6A)
9XG  A 201 ( 4.3A)
 1.01A 1wrlE-5w88A:
11.8		 1wrlE-5w88A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1WRL_F_TFPF209_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 5w88 TROPONIN C, TROPONIN
I
(Homo
sapiens) 		5 / 10 LEU A  48
GLN A  50
GLU A  56
MET A  60
MET A  80
 9XG  A 201 ( 4.8A)
None
None
9XG  A 201 (-4.0A)
9XG  A 201 (-4.0A)
 1.45A 1wrlE-5w88A:
11.8
1wrlF-5w88A:
11.2		 1wrlE-5w88A:
100.00
1wrlF-5w88A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1WRL_F_TFPF209_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 5w88 TROPONIN C, TROPONIN
I
(Homo
sapiens) 		6 / 10 MET A  45
LEU A  48
GLN A  50
GLU A  56
MET A  60
MET A  81
 9XG  A 201 (-2.4A)
9XG  A 201 ( 4.8A)
None
None
9XG  A 201 (-4.0A)
9XG  A 201 ( 4.6A)
 0.95A 1wrlE-5w88A:
11.8
1wrlF-5w88A:
11.2		 1wrlE-5w88A:
100.00
1wrlF-5w88A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1WRL_F_TFPF211_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 5w88 TROPONIN C, TROPONIN
I
(Homo
sapiens) 		4 / 7 PHE A  20
LEU A  48
PHE A  77
MET A  81
 None
9XG  A 201 ( 4.8A)
9XG  A 201 (-3.8A)
9XG  A 201 ( 4.6A)
 0.92A 1wrlE-5w88A:
11.8
1wrlF-5w88A:
11.2		 1wrlE-5w88A:
100.00
1wrlF-5w88A:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNW_A_T3A501_2
(THYROID HORMONE
RECEPTOR ALPHA)		 5w88 TROPONIN C, TROPONIN
I
(Homo
sapiens) 		3 / 3 ILE A  36
MET A  45
ARG A  46
 9XG  A 201 ( 3.3A)
9XG  A 201 (-2.4A)
None
 0.91A 4lnwA-5w88A:
undetectable		 4lnwA-5w88A:
17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNW_A_T3A501_2
(THYROID HORMONE
RECEPTOR ALPHA)		 5w88 TROPONIN C, TROPONIN
I
(Homo
sapiens) 		3 / 3 ILE A  61
MET A  45
ARG A  46
 9XG  A 201 ( 4.0A)
9XG  A 201 (-2.4A)
None
 0.79A 4lnwA-5w88A:
undetectable		 4lnwA-5w88A:
17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNX_A_T3A502_2
(THYROID HORMONE
RECEPTOR ALPHA)		 5w88 TROPONIN C, TROPONIN
I
(Homo
sapiens) 		3 / 3 ILE A  36
MET A  45
ARG A  46
 9XG  A 201 ( 3.3A)
9XG  A 201 (-2.4A)
None
 0.90A 4lnxA-5w88A:
undetectable		 4lnxA-5w88A:
17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNX_A_T3A502_2
(THYROID HORMONE
RECEPTOR ALPHA)		 5w88 TROPONIN C, TROPONIN
I
(Homo
sapiens) 		3 / 3 ILE A  61
MET A  45
ARG A  46
 9XG  A 201 ( 4.0A)
9XG  A 201 (-2.4A)
None
 0.77A 4lnxA-5w88A:
undetectable		 4lnxA-5w88A:
17.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RJD_A_TFPA203_1
(CALMODULIN)		 5w88 TROPONIN C, TROPONIN
I
(Homo
sapiens) 		4 / 8 ILE A  36
LEU A  41
MET A  45
VAL A  72
 9XG  A 201 ( 3.3A)
9XG  A 201 (-3.9A)
9XG  A 201 (-2.4A)
9XG  A 201 (-3.8A)
 0.64A 4rjdA-5w88A:
8.1		 4rjdA-5w88A:
33.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RJD_A_TFPA203_1
(CALMODULIN)		 5w88 TROPONIN C, TROPONIN
I
(Homo
sapiens) 		4 / 8 ILE A  36
LEU A  41
MET A  60
VAL A  72
 9XG  A 201 ( 3.3A)
9XG  A 201 (-3.9A)
9XG  A 201 (-4.0A)
9XG  A 201 (-3.8A)
 0.34A 4rjdA-5w88A:
8.1		 4rjdA-5w88A:
33.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RJD_A_TFPA203_1
(CALMODULIN)		 5w88 TROPONIN C, TROPONIN
I
(Homo
sapiens) 		4 / 8 PHE A  27
LEU A  41
MET A  60
VAL A  72
 9XG  A 201 (-3.8A)
9XG  A 201 (-3.9A)
9XG  A 201 (-4.0A)
9XG  A 201 (-3.8A)
 0.58A 4rjdA-5w88A:
8.1		 4rjdA-5w88A:
33.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RJD_B_TFPB203_1
(CALMODULIN)		 5w88 TROPONIN C, TROPONIN
I
(Homo
sapiens) 		4 / 7 PHE A  27
LEU A  41
MET A  60
MET A  81
 9XG  A 201 (-3.8A)
9XG  A 201 (-3.9A)
9XG  A 201 (-4.0A)
9XG  A 201 ( 4.6A)
 0.87A 4rjdB-5w88A:
7.8		 4rjdB-5w88A:
33.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5w88 TROPONIN C, TROPONIN
I
(Homo
sapiens) 		4 / 7 PHE A  77
GLU A  63
MET A  60
VAL A  72
 9XG  A 201 (-3.8A)
None
9XG  A 201 (-4.0A)
9XG  A 201 (-3.8A)
 1.46A 5ad4A-5w88A:
undetectable
5ad4B-5w88A:
undetectable		 5ad4A-5w88A:
15.25
5ad4B-5w88A:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD6_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5w88 TROPONIN C, TROPONIN
I
(Homo
sapiens) 		4 / 7 PHE A  77
GLU A  63
MET A  60
VAL A  72
 9XG  A 201 (-3.8A)
None
9XG  A 201 (-4.0A)
9XG  A 201 (-3.8A)
 1.42A 5ad6A-5w88A:
undetectable
5ad6B-5w88A:
undetectable		 5ad6A-5w88A:
15.25
5ad6B-5w88A:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FW0_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5w88 TROPONIN C, TROPONIN
I
(Homo
sapiens) 		4 / 7 PHE A  77
GLU A  63
MET A  60
VAL A  72
 9XG  A 201 (-3.8A)
None
9XG  A 201 (-4.0A)
9XG  A 201 (-3.8A)
 1.44A 5fw0A-5w88A:
undetectable
5fw0B-5w88A:
undetectable		 5fw0A-5w88A:
15.25
5fw0B-5w88A:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNU_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5w88 TROPONIN C, TROPONIN
I
(Homo
sapiens) 		4 / 7 PHE A  77
GLU A  63
MET A  60
VAL A  72
 9XG  A 201 (-3.8A)
None
9XG  A 201 (-4.0A)
9XG  A 201 (-3.8A)
 1.47A 5unuA-5w88A:
undetectable
5unuB-5w88A:
undetectable		 5unuA-5w88A:
15.25
5unuB-5w88A:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5w88 TROPONIN C, TROPONIN
I
(Homo
sapiens) 		4 / 7 MET A  60
VAL A  72
PHE A  77
GLU A  63
 9XG  A 201 (-4.0A)
9XG  A 201 (-3.8A)
9XG  A 201 (-3.8A)
None
 1.48A 5unxA-5w88A:
undetectable
5unxB-5w88A:
undetectable		 5unxA-5w88A:
15.25
5unxB-5w88A:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO3_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5w88 TROPONIN C, TROPONIN
I
(Homo
sapiens) 		4 / 7 PHE A  77
GLU A  63
MET A  60
VAL A  72
 9XG  A 201 (-3.8A)
None
9XG  A 201 (-4.0A)
9XG  A 201 (-3.8A)
 1.45A 5uo3A-5w88A:
undetectable
5uo3B-5w88A:
undetectable		 5uo3A-5w88A:
15.40
5uo3B-5w88A:
15.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO5_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5w88 TROPONIN C, TROPONIN
I
(Homo
sapiens) 		4 / 7 PHE A  77
GLU A  63
MET A  60
VAL A  72
 9XG  A 201 (-3.8A)
None
9XG  A 201 (-4.0A)
9XG  A 201 (-3.8A)
 1.45A 5uo5A-5w88A:
undetectable
5uo5B-5w88A:
undetectable		 5uo5A-5w88A:
15.40
5uo5B-5w88A:
15.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO6_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5w88 TROPONIN C, TROPONIN
I
(Homo
sapiens) 		4 / 7 PHE A  77
GLU A  63
MET A  60
VAL A  72
 9XG  A 201 (-3.8A)
None
9XG  A 201 (-4.0A)
9XG  A 201 (-3.8A)
 1.44A 5uo6A-5w88A:
undetectable
5uo6B-5w88A:
undetectable		 5uo6A-5w88A:
15.40
5uo6B-5w88A:
15.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO7_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5w88 TROPONIN C, TROPONIN
I
(Homo
sapiens) 		4 / 7 PHE A  77
GLU A  63
MET A  60
VAL A  72
 9XG  A 201 (-3.8A)
None
9XG  A 201 (-4.0A)
9XG  A 201 (-3.8A)
 1.46A 5uo7A-5w88A:
undetectable
5uo7B-5w88A:
undetectable		 5uo7A-5w88A:
15.40
5uo7B-5w88A:
15.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUI_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5w88 TROPONIN C, TROPONIN
I
(Homo
sapiens) 		4 / 7 PHE A  77
GLU A  63
MET A  60
VAL A  72
 9XG  A 201 (-3.8A)
None
9XG  A 201 (-4.0A)
9XG  A 201 (-3.8A)
 1.44A 5vuiA-5w88A:
undetectable
5vuiB-5w88A:
undetectable		 5vuiA-5w88A:
15.25
5vuiB-5w88A:
15.25