SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '9X5'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACL_C_REAC503_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5ojl IMINE REDUCTASE
(Aspergillus
terreus) 		6 / 10 ILE A 137
ALA A 135
ALA A 125
ALA A 132
ILE A  68
CYH A  70
 None
None
9X5  A 301 ( 4.8A)
None
None
None
 1.26A 2aclC-5ojlA:
undetectable		 2aclC-5ojlA:
13.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACL_E_REAE504_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5ojl IMINE REDUCTASE
(Aspergillus
terreus) 		6 / 11 ILE A 137
ALA A 135
ALA A 125
ALA A 132
ILE A  68
CYH A  70
 None
None
9X5  A 301 ( 4.8A)
None
None
None
 1.22A 2aclE-5ojlA:
undetectable		 2aclE-5ojlA:
13.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FAL_A_REAA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5ojl IMINE REDUCTASE
(Aspergillus
terreus) 		6 / 10 ILE A 137
ALA A 135
ALA A 125
ALA A 132
ILE A  68
CYH A  70
 None
None
9X5  A 301 ( 4.8A)
None
None
None
 1.25A 3falA-5ojlA:
undetectable		 3falA-5ojlA:
13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FAL_C_REAC501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5ojl IMINE REDUCTASE
(Aspergillus
terreus) 		6 / 10 ILE A 137
ALA A 135
ALA A 125
ALA A 132
ILE A  68
CYH A  70
 None
None
9X5  A 301 ( 4.8A)
None
None
None
 1.28A 3falC-5ojlA:
undetectable		 3falC-5ojlA:
13.41