SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '9TD'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QU3_A_MRCA993_1
(ISOLEUCYL-TRNA
SYNTHETASE)		 5w19 TRYPTOPHANASE
(Proteus
vulgaris) 		5 / 12 HIS A  98
GLY A 102
ASN A 105
HIS A 138
LYS A 265
 None
None
None
None
9TD  A 502 (-4.8A)
 1.31A 1qu3A-5w19A:
undetectable		 1qu3A-5w19A:
7.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G08_A_Z80A1187_1
(FREQUENIN 2)		 5w19 TRYPTOPHANASE
(Proteus
vulgaris) 		4 / 6 ILE A 218
PHE A 219
PHE A 167
THR A 190
 None
None
None
9TD  A 502 ( 4.5A)
 1.17A 5g08A-5w19A:
undetectable		 5g08A-5w19A:
16.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A7P_B_9SCB601_1
(SERUM ALBUMIN)		 5w19 TRYPTOPHANASE
(Proteus
vulgaris) 		4 / 6 ASN A 194
CYH A 193
PHE A 356
LEU A 395
 9TD  A 502 (-3.4A)
None
None
None
 1.10A 6a7pB-5w19A:
undetectable		 6a7pB-5w19A:
undetectable