SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '9P2'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6O_B_SAMB500_0
(HYPOTHETICAL PROTEIN)		 5o9h C5A ANAPHYLATOXIN
CHEMOTACTIC RECEPTOR
1
(Homo
sapiens) 		4 / 6 VAL A 248
PHE A 211
PRO A 214
THR A 217
 OLA  A 417 ( 4.9A)
None
9P2  A 401 (-3.8A)
9P2  A 401 (-3.9A)
 1.46A 2q6oB-5o9hA:
undetectable		 2q6oB-5o9hA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HS1_A_VORA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5o9h C5A ANAPHYLATOXIN
CHEMOTACTIC RECEPTOR
1
(Homo
sapiens) 		4 / 8 PHE A 251
GLY A 210
LEU A 167
LEU A 163
 None
None
None
9P2  A 401 (-4.7A)
 0.88A 5hs1A-5o9hA:
undetectable		 5hs1A-5o9hA:
11.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND3_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 5o9h C5A ANAPHYLATOXIN
CHEMOTACTIC RECEPTOR
1
(Homo
sapiens) 		5 / 12 VAL A  58
LEU A 127
ALA A  79
THR A 129
ARG A 134
 None
None
None
9P2  A 401 (-4.4A)
None
 1.22A 5nd3B-5o9hA:
undetectable		 5nd3B-5o9hA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZJI_B_PQNB842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 5o9h C5A ANAPHYLATOXIN
CHEMOTACTIC RECEPTOR
1
(Homo
sapiens) 		5 / 10 ILE A 124
TRP A 154
ILE A  70
ALA A 153
ALA A 158
 9P2  A 401 (-4.4A)
None
TLA  A 402 (-3.3A)
OLA  A 404 ( 4.0A)
OLA  A 416 (-3.5A)
 1.43A 5zjiB-5o9hA:
2.1		 5zjiB-5o9hA:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZJI_B_PQNB842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 6c1q SOLUBLE CYTOCHROME
B562, C5A
ANAPHYLATOXIN
CHEMOTACTIC RECEPTOR
1 CHIMERA
(Escherichia
coli;
Homo
sapiens) 		5 / 10 ILE B 210
TRP B 240
ILE B 156
ALA B 239
ALA B 244
 9P2  B 501 (-4.3A)
None
None
None
None
 1.25A 5zjiB-6c1qB:
2.6		 5zjiB-6c1qB:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HQB_B_PQNB2002_0
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 5o9h C5A ANAPHYLATOXIN
CHEMOTACTIC RECEPTOR
1
(Homo
sapiens) 		5 / 9 TRP A 161
ILE A  70
ALA A 153
LEU A 156
ALA A 160
 None
TLA  A 402 (-3.3A)
OLA  A 404 ( 4.0A)
9P2  A 401 (-3.9A)
9P2  A 401 ( 3.9A)
 1.46A 6hqbB-5o9hA:
1.2		 6hqbB-5o9hA:
22.35