SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '9KH'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5D4U_A_SAMA301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 5o4m HCGC
(Methanococcus
maripaludis) 		9 / 12 GLY A  49
TYR A  51
LEU A  52
ILE A  73
LEU A  91
THR A 113
GLY A 117
GLY A 176
PHE A 213
 SAH  A 301 (-3.4A)
None
SAH  A 301 ( 4.3A)
SAH  A 301 (-3.9A)
SAH  A 301 ( 3.9A)
SAH  A 301 ( 4.1A)
SAH  A 301 (-3.4A)
9KH  A 302 ( 3.3A)
SAH  A 301 (-4.8A)
 0.40A 5d4uA-5o4mA:
36.1		 5d4uA-5o4mA:
51.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5D4U_A_SAMA301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 5o4m HCGC
(Methanococcus
maripaludis) 		5 / 12 TYR A  51
LEU A  52
GLY A 116
GLY A 176
PHE A 213
 None
SAH  A 301 ( 4.3A)
None
9KH  A 302 ( 3.3A)
SAH  A 301 (-4.8A)
 0.89A 5d4uA-5o4mA:
36.1		 5d4uA-5o4mA:
51.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5D4U_B_SAMB301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 5o4m HCGC
(Methanococcus
maripaludis) 		9 / 12 GLY A  49
TYR A  51
LEU A  52
ILE A  73
LEU A  91
THR A 113
GLY A 117
GLY A 176
PHE A 213
 SAH  A 301 (-3.4A)
None
SAH  A 301 ( 4.3A)
SAH  A 301 (-3.9A)
SAH  A 301 ( 3.9A)
SAH  A 301 ( 4.1A)
SAH  A 301 (-3.4A)
9KH  A 302 ( 3.3A)
SAH  A 301 (-4.8A)
 0.42A 5d4uB-5o4mA:
35.8		 5d4uB-5o4mA:
51.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5D4U_B_SAMB301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 5o4m HCGC
(Methanococcus
maripaludis) 		5 / 12 TYR A  51
LEU A  52
GLY A 116
GLY A 176
PHE A 213
 None
SAH  A 301 ( 4.3A)
None
9KH  A 302 ( 3.3A)
SAH  A 301 (-4.8A)
 0.95A 5d4uB-5o4mA:
35.8		 5d4uB-5o4mA:
51.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5D4U_C_SAMC301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 5o4m HCGC
(Methanococcus
maripaludis) 		8 / 12 GLY A  49
TYR A  51
LEU A  52
ILE A  73
LEU A  91
THR A 113
GLY A 117
GLY A 176
 SAH  A 301 (-3.4A)
None
SAH  A 301 ( 4.3A)
SAH  A 301 (-3.9A)
SAH  A 301 ( 3.9A)
SAH  A 301 ( 4.1A)
SAH  A 301 (-3.4A)
9KH  A 302 ( 3.3A)
 0.30A 5d4uC-5o4mA:
36.4		 5d4uC-5o4mA:
51.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5D4U_D_SAMD301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 5o4m HCGC
(Methanococcus
maripaludis) 		8 / 12 GLY A  49
TYR A  51
LEU A  52
ILE A  73
LEU A  91
THR A 113
GLY A 117
GLY A 176
 SAH  A 301 (-3.4A)
None
SAH  A 301 ( 4.3A)
SAH  A 301 (-3.9A)
SAH  A 301 ( 3.9A)
SAH  A 301 ( 4.1A)
SAH  A 301 (-3.4A)
9KH  A 302 ( 3.3A)
 0.33A 5d4uD-5o4mA:
36.2		 5d4uD-5o4mA:
51.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHZ_C_REAC602_1
(ALDEHYDE
DEHYDROGENASE FAMILY
1 MEMBER A3)		 5o4m HCGC
(Methanococcus
maripaludis) 		5 / 10 GLY A 176
THR A 165
GLN A  74
LEU A 112
LEU A 163
 9KH  A 302 ( 3.3A)
None
None
SAH  A 301 (-4.9A)
None
 1.18A 5fhzC-5o4mA:
2.1		 5fhzC-5o4mA:
19.55