SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '9JE'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EE2_A_CHDA1150_0 (ALCOHOL DEHYDROGENASE)	5o3m	PROTOCATECHUATE DECARBOXYLASE (Klebsiella pneumoniae)	5 / 11	LEU A 234 LEU A 330 LEU A 212 VAL A 167 ILE A 169	None 9JE A 601 ( 4.3A) None None 9JE A 601 ( 4.5A)	1.09A	1ee2A-5o3mA: undetectable	1ee2A-5o3mA: 22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EE2_B_CHDB1250_1 (ALCOHOL DEHYDROGENASE)	5o3m	PROTOCATECHUATE DECARBOXYLASE (Klebsiella pneumoniae)	5 / 11	LEU A 234 LEU A 330 LEU A 212 VAL A 167 ILE A 169	None 9JE A 601 ( 4.3A) None None 9JE A 601 ( 4.5A)	1.11A	1ee2B-5o3mA: undetectable	1ee2B-5o3mA: 22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2F8D_A_BEZA1002_0 (HTH-TYPE TRANSCRIPTIONAL REGULATOR BENM)	5o3m	PROTOCATECHUATE DECARBOXYLASE (Klebsiella pneumoniae)	5 / 10	GLY A 332 LEU A 333 LEU A 330 ILE A 218 ARG A 79	None None 9JE A 601 ( 4.3A) None None	1.04A	2f8dA-5o3mA: undetectable	2f8dA-5o3mA: 17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2F8D_B_BEZB1003_0 (HTH-TYPE TRANSCRIPTIONAL REGULATOR BENM)	5o3m	PROTOCATECHUATE DECARBOXYLASE (Klebsiella pneumoniae)	5 / 10	GLY A 332 LEU A 333 LEU A 330 ILE A 218 ARG A 79	None None 9JE A 601 ( 4.3A) None None	1.01A	2f8dB-5o3mA: undetectable	2f8dB-5o3mA: 17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3VW7_A_VPXA2001_2 (PROTEINASE-ACTIVATED RECEPTOR 1, LYSOZYME)	5o3m	PROTOCATECHUATE DECARBOXYLASE (Klebsiella pneumoniae)	4 / 4	PRO A 440 LEU A 438 HIS A 327 LEU A 330	None None 9JE A 601 (-4.3A) 9JE A 601 ( 4.3A)	1.21A	3vw7A-5o3mA: undetectable	3vw7A-5o3mA: 21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HRQ_G_IPHG101_0 (INSULIN A-CHAIN INSULIN B-CHAIN)	5o3m	PROTOCATECHUATE DECARBOXYLASE (Klebsiella pneumoniae)	4 / 6	HIS A 327 LEU A 330 CYH A 150 LEU A 320	9JE A 601 (-4.3A) 9JE A 601 ( 4.3A) None None	1.45A	5hrqD-5o3mA: undetectable 5hrqG-5o3mA: undetectable 5hrqH-5o3mA: undetectable	5hrqD-5o3mA: 4.59 5hrqG-5o3mA: 3.70 5hrqH-5o3mA: 4.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5Z86_W_CHDW101_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	5o3m	PROTOCATECHUATE DECARBOXYLASE (Klebsiella pneumoniae)	5 / 6	ILE A 367 ARG A 420 MET A 417 THR A 418 LEU A 414	None 9JE A 602 ( 3.6A) None None None	1.49A	5z86N-5o3mA: undetectable 5z86W-5o3mA: undetectable	5z86N-5o3mA: 23.71 5z86W-5o3mA: 8.80

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1EE2_A_CHDA1150_0","ALCOHOL DEHYDROGENASE","5o3m","PROTOCATECHUATE DECARBOXYLASE","Klebsiella pneumoniae",5,"LEU A 234;LEU A 330;LEU A 212;VAL A 167;ILE A 169","None;9JE A 601 ( 4.3A);None;None;9JE A 601 ( 4.5A)","1.09A","1ee2A-5o3mA:undetectable",null],["1EE2_B_CHDB1250_1","ALCOHOL DEHYDROGENASE","5o3m","PROTOCATECHUATE DECARBOXYLASE","Klebsiella pneumoniae",5,"LEU A 234;LEU A 330;LEU A 212;VAL A 167;ILE A 169","None;9JE A 601 ( 4.3A);None;None;9JE A 601 ( 4.5A)","1.11A","1ee2B-5o3mA:undetectable","1ee2A-5o3mA:22.35"],["2F8D_A_BEZA1002_0","HTH-TYPE TRANSCRIPTIONAL REGULATOR BENM","5o3m","PROTOCATECHUATE DECARBOXYLASE","Klebsiella pneumoniae",5,"GLY A 332;LEU A 333;LEU A 330;ILE A 218;ARG A  79","None;None;9JE A 601 ( 4.3A);None;None","1.04A","2f8dA-5o3mA:undetectable","1ee2B-5o3mA:22.35"],["2F8D_B_BEZB1003_0","HTH-TYPE TRANSCRIPTIONAL REGULATOR BENM","5o3m","PROTOCATECHUATE DECARBOXYLASE","Klebsiella pneumoniae",5,"GLY A 332;LEU A 333;LEU A 330;ILE A 218;ARG A  79","None;None;9JE A 601 ( 4.3A);None;None","1.01A","2f8dB-5o3mA:undetectable","2f8dA-5o3mA:17.59"],["3VW7_A_VPXA2001_2","PROTEINASE-ACTIVATED RECEPTOR 1, LYSOZYME","5o3m","PROTOCATECHUATE DECARBOXYLASE","Klebsiella pneumoniae",4,"PRO A 440;LEU A 438;HIS A 327;LEU A 330","None;None;9JE A 601 (-4.3A);9JE A 601 ( 4.3A)","1.21A","3vw7A-5o3mA:undetectable","2f8dB-5o3mA:17.59"],["5HRQ_G_IPHG101_0","INSULIN A-CHAIN;INSULIN B-CHAIN","5o3m","PROTOCATECHUATE DECARBOXYLASE","Klebsiella pneumoniae",4,"HIS A 327;LEU A 330;CYH A 150;LEU A 320","9JE A 601 (-4.3A);9JE A 601 ( 4.3A);None;None","1.45A","5hrqD-5o3mA:undetectable;5hrqG-5o3mA:undetectable;5hrqH-5o3mA:undetectable","3vw7A-5o3mA:21.54"],["5Z86_W_CHDW101_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","5o3m","PROTOCATECHUATE DECARBOXYLASE","Klebsiella pneumoniae",5,"ILE A 367;ARG A 420;MET A 417;THR A 418;LEU A 414","None;9JE A 602 ( 3.6A);None;None;None","1.49A","5z86N-5o3mA:undetectable;5z86W-5o3mA:undetectable","5hrqD-5o3mA:4.59;5hrqG-5o3mA:3.70;5hrqH-5o3mA:4.59"]]