SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '9FU'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HYY_C_STIC600_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 5zm4 DIOXYGENASE ANDA
(Aspergillus
stellatus) 		4 / 6 VAL A  54
MET A  55
ILE A 225
MET A  73
 None
None
None
9FU  A 303 ( 4.5A)
 1.17A 2hyyC-5zm4A:
undetectable		 2hyyC-5zm4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VJ1_A_BEZA1303_0
(SARS CORONAVIRUS
MAIN PROTEINASE)		 5zm4 DIOXYGENASE ANDA
(Aspergillus
stellatus) 		3 / 3 HIS A  79
MET A  73
MET A 125
 AKG  A 302 (-4.2A)
9FU  A 303 ( 4.5A)
AKG  A 302 ( 4.7A)
 1.42A 2vj1A-5zm4A:
undetectable		 2vj1A-5zm4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QCK_A_ASDA404_1
(3-KETOSTEROID-9-ALPH
A-MONOOXYGENASE
OXYGENASE SUBUNIT)		 5zm4 DIOXYGENASE ANDA
(Aspergillus
stellatus) 		5 / 12 LEU A 123
ALA A 230
MET A 156
ASN A 158
GLY A 214
 AKG  A 302 ( 3.6A)
9FU  A 303 (-3.5A)
9FU  A 303 ( 4.0A)
9FU  A 303 (-4.3A)
AKG  A 302 ( 3.9A)
 1.09A 4qckA-5zm4A:
undetectable		 4qckA-5zm4A:
undetectable