SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '9FQ'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1S9P_B_DESB459_1 (ESTROGEN-RELATED RECEPTOR GAMMA)	5o0s	GLUCOSYLCERAMIDASE (Thermoanaerobact erium xylanolyticum)	5 / 12	LEU A 451 GLU A 777 VAL A 735 TYR A 456 LEU A 607	None 9FQ A 911 (-3.6A) None None None	1.22A	1s9pB-5o0sA: undetectable	1s9pB-5o0sA: 14.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OXT_C_SAMC300_1 (NUCLEOSIDE-2'-O-METH YLTRANSFERASE)	5o0s	GLUCOSYLCERAMIDASE (Thermoanaerobact erium xylanolyticum)	4 / 4	SER A 512 GLY A 99 HIS A 507 ASP A 593	None None 9FQ A 911 (-3.9A) 9FQ A 911 (-3.5A)	1.35A	2oxtC-5o0sA: undetectable	2oxtC-5o0sA: 14.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QO4_A_CHDA130_0 (LIVER-BASIC FATTY ACID BINDING PROTEIN)	5o0s	GLUCOSYLCERAMIDASE (Thermoanaerobact erium xylanolyticum)	5 / 12	TYR A 603 THR A 594 ASP A 593 HIS A 660 MET A 665	None None 9FQ A 911 (-3.5A) None None	1.30A	2qo4A-5o0sA: undetectable	2qo4A-5o0sA: 10.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QO6_A_CHDA130_0 (LIVER-BASIC FATTY ACID BINDING PROTEIN)	5o0s	GLUCOSYLCERAMIDASE (Thermoanaerobact erium xylanolyticum)	5 / 12	TYR A 603 THR A 594 ASP A 593 HIS A 660 MET A 665	None None 9FQ A 911 (-3.5A) None None	1.31A	2qo6A-5o0sA: 5.3	2qo6A-5o0sA: 10.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QN9_B_DXCB607_0 (N-ACYL-PHOSPHATIDYLE THANOLAMINE-HYDROLYZ ING PHOSPHOLIPASE D)	5o0s	GLUCOSYLCERAMIDASE (Thermoanaerobact erium xylanolyticum)	4 / 4	TYR A 456 TRP A 732 ARG A 792 TYR A 603	None 9FQ A 911 (-4.7A) 9FQ A 911 (-3.6A) None	1.39A	4qn9A-5o0sA: 0.1 4qn9B-5o0sA: 0.1	4qn9A-5o0sA: 18.59 4qn9B-5o0sA: 18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ZP0_A_DXCA500_0 (MULTIDRUG TRANSPORTER MDFA)	5o0s	GLUCOSYLCERAMIDASE (Thermoanaerobact erium xylanolyticum)	5 / 10	TYR A 523 ASN A 521 ASP A 508 LEU A 534 GLN A 590	9FQ A 911 (-4.0A) None None None None	1.25A	4zp0A-5o0sA: 1.1	4zp0A-5o0sA: 19.25

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1S9P_B_DESB459_1","ESTROGEN-RELATED RECEPTOR GAMMA","5o0s","GLUCOSYLCERAMIDASE","Thermoanaerobacterium xylanolyticum",5,"LEU A 451;GLU A 777;VAL A 735;TYR A 456;LEU A 607","None;9FQ A 911 (-3.6A);None;None;None","1.22A","1s9pB-5o0sA:undetectable",null],["2OXT_C_SAMC300_1","NUCLEOSIDE-2'-O-METHYLTRANSFERASE","5o0s","GLUCOSYLCERAMIDASE","Thermoanaerobacterium xylanolyticum",4,"SER A 512;GLY A  99;HIS A 507;ASP A 593","None;None;9FQ A 911 (-3.9A);9FQ A 911 (-3.5A)","1.35A","2oxtC-5o0sA:undetectable","1s9pB-5o0sA:14.25"],["2QO4_A_CHDA130_0","LIVER-BASIC FATTY ACID BINDING PROTEIN","5o0s","GLUCOSYLCERAMIDASE","Thermoanaerobacterium xylanolyticum",5,"TYR A 603;THR A 594;ASP A 593;HIS A 660;MET A 665","None;None;9FQ A 911 (-3.5A);None;None","1.30A","2qo4A-5o0sA:undetectable","2oxtC-5o0sA:14.92"],["2QO6_A_CHDA130_0","LIVER-BASIC FATTY ACID BINDING PROTEIN","5o0s","GLUCOSYLCERAMIDASE","Thermoanaerobacterium xylanolyticum",5,"TYR A 603;THR A 594;ASP A 593;HIS A 660;MET A 665","None;None;9FQ A 911 (-3.5A);None;None","1.31A","2qo6A-5o0sA:5.3","2qo4A-5o0sA:10.41"],["4QN9_B_DXCB607_0","N-ACYL-PHOSPHATIDYLETHANOLAMINE-HYDROLYZING PHOSPHOLIPASE D","5o0s","GLUCOSYLCERAMIDASE","Thermoanaerobacterium xylanolyticum",4,"TYR A 456;TRP A 732;ARG A 792;TYR A 603","None;9FQ A 911 (-4.7A);9FQ A 911 (-3.6A);None","1.39A","4qn9A-5o0sA:0.1;4qn9B-5o0sA:0.1","2qo6A-5o0sA:10.28"],["4ZP0_A_DXCA500_0","MULTIDRUG TRANSPORTER MDFA","5o0s","GLUCOSYLCERAMIDASE","Thermoanaerobacterium xylanolyticum",5,"TYR A 523;ASN A 521;ASP A 508;LEU A 534;GLN A 590","9FQ A 911 (-4.0A);None;None;None;None","1.25A","4zp0A-5o0sA:1.1","4qn9A-5o0sA:18.59;4qn9B-5o0sA:18.59"]]