SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '9CX'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1WSV_A_THHA3001_0 (AMINOMETHYLTRANSFERA SE)	5zh5	LYSINE--TRNA LIGASE (Plasmodium falciparum)	5 / 12	MET A 494 THR A 561 LEU A 564 ILE A 560 VAL A 501	None None None None 9CX A 602 (-4.8A)	1.35A	1wsvA-5zh5A: undetectable	1wsvA-5zh5A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1WSV_B_THHB4001_0 (AMINOMETHYLTRANSFERA SE)	5zh5	LYSINE--TRNA LIGASE (Plasmodium falciparum)	5 / 12	MET A 494 THR A 561 LEU A 564 ILE A 560 VAL A 501	None None None None 9CX A 602 (-4.8A)	1.35A	1wsvB-5zh5A: undetectable	1wsvB-5zh5A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3IA4_C_MTXC164_2 (DIHYDROFOLATE REDUCTASE)	5zh5	LYSINE--TRNA LIGASE (Plasmodium falciparum)	4 / 4	ILE A 403 ARG A 559 ILE A 468 THR A 489	None 9CX A 602 (-3.3A) None None	1.03A	3ia4C-5zh5A: undetectable	3ia4C-5zh5A: 18.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6BNI_A_ADNA602_1 (LYSINE--TRNA LIGASE)	5zh5	LYSINE--TRNA LIGASE (Plasmodium falciparum)	6 / 10	HIS A 338 PHE A 342 GLU A 500 GLY A 556 ARG A 559 ILE A 570	9CX A 602 (-4.1A) 9CX A 602 (-3.8A) 9CX A 602 (-4.0A) 9CX A 602 (-3.7A) 9CX A 602 (-3.3A) 9CX A 602 (-4.9A)	0.40A	6bniA-5zh5A: 45.6	6bniA-5zh5A: 33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6BNI_B_ADNB602_1 (LYSINE--TRNA LIGASE)	5zh5	LYSINE--TRNA LIGASE (Plasmodium falciparum)	6 / 10	HIS A 338 PHE A 342 GLU A 500 GLY A 556 ARG A 559 ILE A 570	9CX A 602 (-4.1A) 9CX A 602 (-3.8A) 9CX A 602 (-4.0A) 9CX A 602 (-3.7A) 9CX A 602 (-3.3A) 9CX A 602 (-4.9A)	0.40A	6bniB-5zh5A: 45.4	6bniB-5zh5A: 33.33

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1WSV_A_THHA3001_0","AMINOMETHYLTRANSFERASE","5zh5","LYSINE--TRNA LIGASE","Plasmodium falciparum",5,"MET A 494;THR A 561;LEU A 564;ILE A 560;VAL A 501","None;None;None;None;9CX A 602 (-4.8A)","1.35A","1wsvA-5zh5A:undetectable",null],["1WSV_B_THHB4001_0","AMINOMETHYLTRANSFERASE","5zh5","LYSINE--TRNA LIGASE","Plasmodium falciparum",5,"MET A 494;THR A 561;LEU A 564;ILE A 560;VAL A 501","None;None;None;None;9CX A 602 (-4.8A)","1.35A","1wsvB-5zh5A:undetectable","1wsvA-5zh5A:undetectable"],["3IA4_C_MTXC164_2","DIHYDROFOLATE REDUCTASE","5zh5","LYSINE--TRNA LIGASE","Plasmodium falciparum",4,"ILE A 403;ARG A 559;ILE A 468;THR A 489","None;9CX A 602 (-3.3A);None;None","1.03A","3ia4C-5zh5A:undetectable","1wsvB-5zh5A:undetectable"],["6BNI_A_ADNA602_1","LYSINE--TRNA LIGASE","5zh5","LYSINE--TRNA LIGASE","Plasmodium falciparum",6,"HIS A 338;PHE A 342;GLU A 500;GLY A 556;ARG A 559;ILE A 570","9CX A 602 (-4.1A);9CX A 602 (-3.8A);9CX A 602 (-4.0A);9CX A 602 (-3.7A);9CX A 602 (-3.3A);9CX A 602 (-4.9A)","0.40A","6bniA-5zh5A:45.6","3ia4C-5zh5A:18.52"],["6BNI_B_ADNB602_1","LYSINE--TRNA LIGASE","5zh5","LYSINE--TRNA LIGASE","Plasmodium falciparum",6,"HIS A 338;PHE A 342;GLU A 500;GLY A 556;ARG A 559;ILE A 570","9CX A 602 (-4.1A);9CX A 602 (-3.8A);9CX A 602 (-4.0A);9CX A 602 (-3.7A);9CX A 602 (-3.3A);9CX A 602 (-4.9A)","0.40A","6bniB-5zh5A:45.4","6bniA-5zh5A:33.33"]]