SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '9CR'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1A52_A_ESTA1_1
(ESTROGEN RECEPTOR)		 1xls RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		5 / 10 ALA A 272
LEU A 309
ARG A 316
ILE A 345
LEU A 436
 9CR  A 801 (-3.5A)
9CR  A 801 (-4.2A)
9CR  A 801 (-2.6A)
9CR  A 801 ( 4.5A)
9CR  A 801 (-4.7A)
 1.03A 1a52A-1xlsA:
23.8		 1a52A-1xlsA:
31.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1A52_B_ESTB2_1
(ESTROGEN RECEPTOR)		 1xls RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		5 / 10 ALA A 272
LEU A 309
ARG A 316
ILE A 345
LEU A 436
 9CR  A 801 (-3.5A)
9CR  A 801 (-4.2A)
9CR  A 801 (-2.6A)
9CR  A 801 ( 4.5A)
9CR  A 801 (-4.7A)
 1.02A 1a52B-1xlsA:
23.7		 1a52B-1xlsA:
31.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AX9_A_EDRA999_1
(ACETYLCHOLINESTERASE)		 1xiu RXR-LIKE PROTEIN
(Biomphalaria
glabrata) 		4 / 8 GLY A 315
PHE A 412
PHE A 413
HIS A 409
 None
None
None
9CR  A 201 (-4.8A)
 0.93A 1ax9A-1xiuA:
undetectable		 1ax9A-1xiuA:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AX9_A_EDRA999_1
(ACETYLCHOLINESTERASE)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		4 / 8 GLY A 341
PHE A 438
PHE A 439
HIS A 435
 None
None
None
9CR  A7223 (-4.3A)
 1.00A 1ax9A-3dzuA:
undetectable		 1ax9A-3dzuA:
22.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ERE_A_ESTA600_1
(ESTROGEN RECEPTOR)		 1xls RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		5 / 9 ALA A 272
LEU A 309
ARG A 316
ILE A 345
LEU A 436
 9CR  A 801 (-3.5A)
9CR  A 801 (-4.2A)
9CR  A 801 (-2.6A)
9CR  A 801 ( 4.5A)
9CR  A 801 (-4.7A)
 1.03A 1ereA-1xlsA:
25.6		 1ereA-1xlsA:
31.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ERE_B_ESTB600_1
(ESTROGEN RECEPTOR)		 1xls RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		5 / 9 ALA A 272
LEU A 309
ARG A 316
ILE A 345
LEU A 436
 9CR  A 801 (-3.5A)
9CR  A 801 (-4.2A)
9CR  A 801 (-2.6A)
9CR  A 801 ( 4.5A)
9CR  A 801 (-4.7A)
 1.03A 1ereB-1xlsA:
25.6		 1ereB-1xlsA:
31.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ERE_C_ESTC600_1
(ESTROGEN RECEPTOR)		 1xls RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		5 / 9 ALA A 272
LEU A 309
ARG A 316
ILE A 345
LEU A 436
 9CR  A 801 (-3.5A)
9CR  A 801 (-4.2A)
9CR  A 801 (-2.6A)
9CR  A 801 ( 4.5A)
9CR  A 801 (-4.7A)
 1.03A 1ereC-1xlsA:
25.5		 1ereC-1xlsA:
31.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ERE_D_ESTD600_1
(ESTROGEN RECEPTOR)		 1xls RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		5 / 9 ALA A 272
LEU A 309
ARG A 316
ILE A 345
LEU A 436
 9CR  A 801 (-3.5A)
9CR  A 801 (-4.2A)
9CR  A 801 (-2.6A)
9CR  A 801 ( 4.5A)
9CR  A 801 (-4.7A)
 1.03A 1ereD-1xlsA:
25.6		 1ereD-1xlsA:
31.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_E_ESTE600_1
(ESTROGEN RECEPTOR)		 1xiu RXR-LIKE PROTEIN
(Biomphalaria
glabrata) 		4 / 8 ALA A 246
LEU A 283
ARG A 290
LEU A 410
 9CR  A 201 (-3.6A)
9CR  A 201 ( 4.1A)
9CR  A 201 (-2.8A)
9CR  A 201 ( 4.8A)
 0.90A 1ereE-1xiuA:
23.4		 1ereE-1xiuA:
29.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ERE_E_ESTE600_1
(ESTROGEN RECEPTOR)		 1xls RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		4 / 8 ALA A 272
LEU A 309
ARG A 316
LEU A 436
 9CR  A 801 (-3.5A)
9CR  A 801 (-4.2A)
9CR  A 801 (-2.6A)
9CR  A 801 (-4.7A)
 0.89A 1ereE-1xlsA:
25.6		 1ereE-1xlsA:
31.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_E_ESTE600_1
(ESTROGEN RECEPTOR)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		4 / 8 ALA A 272
LEU A 309
ARG A 316
LEU A 436
 9CR  A7223 (-4.2A)
9CR  A7223 ( 4.4A)
9CR  A7223 (-3.7A)
9CR  A7223 ( 4.7A)
 0.86A 1ereE-3dzuA:
25.4		 1ereE-3dzuA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_F_ESTF600_1
(ESTROGEN RECEPTOR)		 1xiu RXR-LIKE PROTEIN
(Biomphalaria
glabrata) 		4 / 8 ALA A 246
LEU A 283
ARG A 290
LEU A 410
 9CR  A 201 (-3.6A)
9CR  A 201 ( 4.1A)
9CR  A 201 (-2.8A)
9CR  A 201 ( 4.8A)
 0.91A 1ereF-1xiuA:
23.4		 1ereF-1xiuA:
29.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ERE_F_ESTF600_1
(ESTROGEN RECEPTOR)		 1xls RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		4 / 8 ALA A 272
LEU A 309
ARG A 316
LEU A 436
 9CR  A 801 (-3.5A)
9CR  A 801 (-4.2A)
9CR  A 801 (-2.6A)
9CR  A 801 (-4.7A)
 0.91A 1ereF-1xlsA:
25.5		 1ereF-1xlsA:
31.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_F_ESTF600_1
(ESTROGEN RECEPTOR)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		4 / 8 ALA A 272
LEU A 309
ARG A 316
LEU A 436
 9CR  A7223 (-4.2A)
9CR  A7223 ( 4.4A)
9CR  A7223 (-3.7A)
9CR  A7223 ( 4.7A)
 0.87A 1ereF-3dzuA:
25.4		 1ereF-3dzuA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_A_RALA600_1
(ESTROGEN RECEPTOR)		 1xiu RXR-LIKE PROTEIN
(Biomphalaria
glabrata) 		5 / 12 ALA A 246
LEU A 250
TRP A 279
ARG A 290
ILE A 402
 9CR  A 201 (-3.6A)
None
None
9CR  A 201 (-2.8A)
None
 1.07A 1errA-1xiuA:
22.2		 1errA-1xiuA:
29.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ERR_A_RALA600_1
(ESTROGEN RECEPTOR)		 1xls RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		5 / 12 ALA A 272
LEU A 276
TRP A 305
ARG A 316
ILE A 428
 9CR  A 801 (-3.5A)
None
None
9CR  A 801 (-2.6A)
None
 1.17A 1errA-1xlsA:
22.1		 1errA-1xlsA:
31.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_A_RALA600_1
(ESTROGEN RECEPTOR)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		5 / 12 ALA A 272
LEU A 276
TRP A 305
ARG A 316
ILE A 428
 9CR  A7223 (-4.2A)
None
None
9CR  A7223 (-3.7A)
None
 1.03A 1errA-3dzuA:
21.9		 1errA-3dzuA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_A_RALA600_1
(ESTROGEN RECEPTOR)		 5uan RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		5 / 12 ALA A 272
LEU A 276
TRP A 305
ARG A 316
ILE A 428
 9CR  A 503 (-3.5A)
None
None
9CR  A 503 (-3.0A)
None
 1.24A 1errA-5uanA:
21.7		 1errA-5uanA:
24.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_B_RALB600_1
(ESTROGEN RECEPTOR)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		5 / 12 ALA A 272
LEU A 276
TRP A 305
LEU A 309
ILE A 428
 9CR  A7223 (-4.2A)
None
None
9CR  A7223 ( 4.4A)
None
 0.87A 1errB-3dzuA:
22.1		 1errB-3dzuA:
20.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FBY_A_9CRA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xiu RXR-LIKE PROTEIN
(Biomphalaria
glabrata) 		12 / 12 ILE A 242
CYH A 243
ALA A 245
ALA A 246
GLN A 249
PHE A 287
ARG A 290
LEU A 300
ALA A 301
VAL A 316
CYH A 406
HIS A 409
 9CR  A 201 ( 4.4A)
9CR  A 201 ( 3.8A)
9CR  A 201 (-3.6A)
9CR  A 201 (-3.6A)
9CR  A 201 (-4.1A)
9CR  A 201 (-4.7A)
9CR  A 201 (-2.8A)
9CR  A 201 (-4.4A)
9CR  A 201 (-3.4A)
9CR  A 201 (-4.2A)
9CR  A 201 (-3.6A)
9CR  A 201 (-4.8A)
 0.33A 1fbyA-1xiuA:
31.8		 1fbyA-1xiuA:
80.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FBY_A_9CRA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xls RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		12 / 12 ILE A 268
CYH A 269
ALA A 271
ALA A 272
GLN A 275
PHE A 313
ARG A 316
LEU A 326
ALA A 327
VAL A 342
CYH A 432
HIS A 435
 9CR  A 801 (-3.9A)
9CR  A 801 ( 4.5A)
9CR  A 801 (-3.6A)
9CR  A 801 (-3.5A)
9CR  A 801 (-4.7A)
9CR  A 801 (-4.3A)
9CR  A 801 (-2.6A)
9CR  A 801 (-4.1A)
9CR  A 801 (-3.3A)
9CR  A 801 ( 4.3A)
9CR  A 801 ( 3.7A)
None
 0.41A 1fbyA-1xlsA:
33.7		 1fbyA-1xlsA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FBY_A_9CRA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		12 / 12 ILE A 268
CYH A 269
ALA A 271
ALA A 272
GLN A 275
PHE A 313
ARG A 316
LEU A 326
ALA A 327
VAL A 342
CYH A 432
HIS A 435
 9CR  A7223 (-3.9A)
None
9CR  A7223 (-3.5A)
9CR  A7223 (-4.2A)
9CR  A7223 (-4.6A)
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
9CR  A7223 ( 4.5A)
9CR  A7223 (-3.8A)
9CR  A7223 (-4.3A)
 0.71A 1fbyA-3dzuA:
33.1		 1fbyA-3dzuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FBY_A_9CRA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5uan RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		11 / 12 ILE A 268
CYH A 269
ALA A 271
ALA A 272
GLN A 275
PHE A 313
ARG A 316
LEU A 326
ALA A 327
VAL A 342
CYH A 432
 9CR  A 503 (-4.0A)
9CR  A 503 ( 4.4A)
9CR  A 503 (-3.5A)
9CR  A 503 (-3.5A)
9CR  A 503 (-3.8A)
9CR  A 503 (-4.7A)
9CR  A 503 (-3.0A)
9CR  A 503 (-4.3A)
9CR  A 503 (-3.4A)
None
9CR  A 503 (-3.3A)
 0.60A 1fbyA-5uanA:
33.3		 1fbyA-5uanA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FBY_A_9CRA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5uan RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		11 / 12 ILE A 268
CYH A 269
ALA A 271
ALA A 272
GLN A 275
PHE A 313
LEU A 326
ALA A 327
VAL A 342
CYH A 432
HIS A 435
 9CR  A 503 (-4.0A)
9CR  A 503 ( 4.4A)
9CR  A 503 (-3.5A)
9CR  A 503 (-3.5A)
9CR  A 503 (-3.8A)
9CR  A 503 (-4.7A)
9CR  A 503 (-4.3A)
9CR  A 503 (-3.4A)
None
9CR  A 503 (-3.3A)
None
 0.52A 1fbyA-5uanA:
33.3		 1fbyA-5uanA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FBY_B_9CRB1500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xiu RXR-LIKE PROTEIN
(Biomphalaria
glabrata) 		12 / 12 ILE A 242
CYH A 243
ALA A 245
ALA A 246
GLN A 249
PHE A 287
ARG A 290
LEU A 300
ALA A 301
VAL A 316
CYH A 406
HIS A 409
 9CR  A 201 ( 4.4A)
9CR  A 201 ( 3.8A)
9CR  A 201 (-3.6A)
9CR  A 201 (-3.6A)
9CR  A 201 (-4.1A)
9CR  A 201 (-4.7A)
9CR  A 201 (-2.8A)
9CR  A 201 (-4.4A)
9CR  A 201 (-3.4A)
9CR  A 201 (-4.2A)
9CR  A 201 (-3.6A)
9CR  A 201 (-4.8A)
 0.31A 1fbyB-1xiuA:
31.3		 1fbyB-1xiuA:
80.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FBY_B_9CRB1500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xls RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		12 / 12 ILE A 268
CYH A 269
ALA A 271
ALA A 272
GLN A 275
PHE A 313
ARG A 316
LEU A 326
ALA A 327
VAL A 342
CYH A 432
HIS A 435
 9CR  A 801 (-3.9A)
9CR  A 801 ( 4.5A)
9CR  A 801 (-3.6A)
9CR  A 801 (-3.5A)
9CR  A 801 (-4.7A)
9CR  A 801 (-4.3A)
9CR  A 801 (-2.6A)
9CR  A 801 (-4.1A)
9CR  A 801 (-3.3A)
9CR  A 801 ( 4.3A)
9CR  A 801 ( 3.7A)
None
 0.39A 1fbyB-1xlsA:
32.9		 1fbyB-1xlsA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FBY_B_9CRB1500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		12 / 12 ILE A 268
CYH A 269
ALA A 271
ALA A 272
GLN A 275
PHE A 313
ARG A 316
LEU A 326
ALA A 327
VAL A 342
CYH A 432
HIS A 435
 9CR  A7223 (-3.9A)
None
9CR  A7223 (-3.5A)
9CR  A7223 (-4.2A)
9CR  A7223 (-4.6A)
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
9CR  A7223 ( 4.5A)
9CR  A7223 (-3.8A)
9CR  A7223 (-4.3A)
 0.72A 1fbyB-3dzuA:
32.4		 1fbyB-3dzuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FBY_B_9CRB1500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5uan RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		11 / 12 ILE A 268
CYH A 269
ALA A 271
ALA A 272
GLN A 275
PHE A 313
ARG A 316
LEU A 326
ALA A 327
VAL A 342
CYH A 432
 9CR  A 503 (-4.0A)
9CR  A 503 ( 4.4A)
9CR  A 503 (-3.5A)
9CR  A 503 (-3.5A)
9CR  A 503 (-3.8A)
9CR  A 503 (-4.7A)
9CR  A 503 (-3.0A)
9CR  A 503 (-4.3A)
9CR  A 503 (-3.4A)
None
9CR  A 503 (-3.3A)
 0.60A 1fbyB-5uanA:
32.4		 1fbyB-5uanA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FBY_B_9CRB1500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5uan RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		11 / 12 ILE A 268
CYH A 269
ALA A 271
ALA A 272
GLN A 275
PHE A 313
LEU A 326
ALA A 327
VAL A 342
CYH A 432
HIS A 435
 9CR  A 503 (-4.0A)
9CR  A 503 ( 4.4A)
9CR  A 503 (-3.5A)
9CR  A 503 (-3.5A)
9CR  A 503 (-3.8A)
9CR  A 503 (-4.7A)
9CR  A 503 (-4.3A)
9CR  A 503 (-3.4A)
None
9CR  A 503 (-3.3A)
None
 0.51A 1fbyB-5uanA:
32.4		 1fbyB-5uanA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FM6_A_9CRA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xiu RXR-LIKE PROTEIN
(Biomphalaria
glabrata) 		12 / 12 ILE A 242
ALA A 245
ALA A 246
GLN A 249
TRP A 279
PHE A 287
ARG A 290
LEU A 300
ALA A 301
VAL A 316
CYH A 406
LEU A 410
 9CR  A 201 ( 4.4A)
9CR  A 201 (-3.6A)
9CR  A 201 (-3.6A)
9CR  A 201 (-4.1A)
None
9CR  A 201 (-4.7A)
9CR  A 201 (-2.8A)
9CR  A 201 (-4.4A)
9CR  A 201 (-3.4A)
9CR  A 201 (-4.2A)
9CR  A 201 (-3.6A)
9CR  A 201 ( 4.8A)
 0.36A 1fm6A-1xiuA:
31.9		 1fm6A-1xiuA:
81.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FM6_A_9CRA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xls RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		12 / 12 ILE A 268
ALA A 271
ALA A 272
GLN A 275
TRP A 305
PHE A 313
ARG A 316
LEU A 326
ALA A 327
VAL A 342
CYH A 432
LEU A 436
 9CR  A 801 (-3.9A)
9CR  A 801 (-3.6A)
9CR  A 801 (-3.5A)
9CR  A 801 (-4.7A)
None
9CR  A 801 (-4.3A)
9CR  A 801 (-2.6A)
9CR  A 801 (-4.1A)
9CR  A 801 (-3.3A)
9CR  A 801 ( 4.3A)
9CR  A 801 ( 3.7A)
9CR  A 801 (-4.7A)
 0.32A 1fm6A-1xlsA:
36.8		 1fm6A-1xlsA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FM6_A_9CRA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		12 / 12 ILE A 268
ALA A 271
ALA A 272
GLN A 275
TRP A 305
PHE A 313
ARG A 316
LEU A 326
ALA A 327
VAL A 342
CYH A 432
LEU A 436
 9CR  A7223 (-3.9A)
9CR  A7223 (-3.5A)
9CR  A7223 (-4.2A)
9CR  A7223 (-4.6A)
None
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
9CR  A7223 ( 4.5A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
 0.67A 1fm6A-3dzuA:
32.4		 1fm6A-3dzuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FM6_A_9CRA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5uan RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		12 / 12 ILE A 268
ALA A 271
ALA A 272
GLN A 275
TRP A 305
PHE A 313
ARG A 316
LEU A 326
ALA A 327
VAL A 342
CYH A 432
LEU A 436
 9CR  A 503 (-4.0A)
9CR  A 503 (-3.5A)
9CR  A 503 (-3.5A)
9CR  A 503 (-3.8A)
None
9CR  A 503 (-4.7A)
9CR  A 503 (-3.0A)
9CR  A 503 (-4.3A)
9CR  A 503 (-3.4A)
None
9CR  A 503 (-3.3A)
9CR  A 503 ( 4.8A)
 0.57A 1fm6A-5uanA:
33.0		 1fm6A-5uanA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FM6_U_9CRU502_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xiu RXR-LIKE PROTEIN
(Biomphalaria
glabrata) 		11 / 12 ALA A 245
ALA A 246
PHE A 287
ARG A 290
LEU A 300
ALA A 301
VAL A 316
ILE A 319
CYH A 406
HIS A 409
LEU A 410
 9CR  A 201 (-3.6A)
9CR  A 201 (-3.6A)
9CR  A 201 (-4.7A)
9CR  A 201 (-2.8A)
9CR  A 201 (-4.4A)
9CR  A 201 (-3.4A)
9CR  A 201 (-4.2A)
None
9CR  A 201 (-3.6A)
9CR  A 201 (-4.8A)
9CR  A 201 ( 4.8A)
 0.33A 1fm6U-1xiuA:
31.7		 1fm6U-1xiuA:
81.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FM6_U_9CRU502_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xiu RXR-LIKE PROTEIN
(Biomphalaria
glabrata) 		6 / 12 TRP A 279
VAL A 316
ILE A 319
CYH A 406
HIS A 409
LEU A 410
 None
9CR  A 201 (-4.2A)
None
9CR  A 201 (-3.6A)
9CR  A 201 (-4.8A)
9CR  A 201 ( 4.8A)
 0.96A 1fm6U-1xiuA:
31.7		 1fm6U-1xiuA:
81.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FM6_U_9CRU502_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xls RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		11 / 12 ALA A 271
ALA A 272
PHE A 313
ARG A 316
LEU A 326
ALA A 327
VAL A 342
ILE A 345
CYH A 432
HIS A 435
LEU A 436
 9CR  A 801 (-3.6A)
9CR  A 801 (-3.5A)
9CR  A 801 (-4.3A)
9CR  A 801 (-2.6A)
9CR  A 801 (-4.1A)
9CR  A 801 (-3.3A)
9CR  A 801 ( 4.3A)
9CR  A 801 ( 4.5A)
9CR  A 801 ( 3.7A)
None
9CR  A 801 (-4.7A)
 0.39A 1fm6U-1xlsA:
36.7		 1fm6U-1xlsA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FM6_U_9CRU502_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xls RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		6 / 12 TRP A 305
VAL A 342
ILE A 345
CYH A 432
HIS A 435
LEU A 436
 None
9CR  A 801 ( 4.3A)
9CR  A 801 ( 4.5A)
9CR  A 801 ( 3.7A)
None
9CR  A 801 (-4.7A)
 1.11A 1fm6U-1xlsA:
36.7		 1fm6U-1xlsA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FM6_U_9CRU502_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		9 / 12 ALA A 271
ALA A 272
PHE A 313
ARG A 316
LEU A 326
ALA A 327
ILE A 428
CYH A 432
LEU A 436
 9CR  A7223 (-3.5A)
9CR  A7223 (-4.2A)
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
None
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
 1.47A 1fm6U-3dzuA:
32.6		 1fm6U-3dzuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FM6_U_9CRU502_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		11 / 12 ALA A 271
ALA A 272
PHE A 313
ARG A 316
LEU A 326
ALA A 327
VAL A 342
ILE A 345
CYH A 432
HIS A 435
LEU A 436
 9CR  A7223 (-3.5A)
9CR  A7223 (-4.2A)
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
9CR  A7223 ( 4.5A)
9CR  A7223 ( 4.9A)
9CR  A7223 (-3.8A)
9CR  A7223 (-4.3A)
9CR  A7223 ( 4.7A)
 0.62A 1fm6U-3dzuA:
32.6		 1fm6U-3dzuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FM6_U_9CRU502_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		6 / 12 TRP A 305
VAL A 342
ILE A 345
CYH A 432
HIS A 435
LEU A 436
 None
9CR  A7223 ( 4.5A)
9CR  A7223 ( 4.9A)
9CR  A7223 (-3.8A)
9CR  A7223 (-4.3A)
9CR  A7223 ( 4.7A)
 1.13A 1fm6U-3dzuA:
32.6		 1fm6U-3dzuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FM6_U_9CRU502_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5uan RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		7 / 12 ALA A 271
ALA A 272
PHE A 313
ARG A 316
LEU A 326
ALA A 327
ILE A 428
 9CR  A 503 (-3.5A)
9CR  A 503 (-3.5A)
9CR  A 503 (-4.7A)
9CR  A 503 (-3.0A)
9CR  A 503 (-4.3A)
9CR  A 503 (-3.4A)
None
 1.24A 1fm6U-5uanA:
33.0		 1fm6U-5uanA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FM6_U_9CRU502_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5uan RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		11 / 12 ALA A 271
ALA A 272
PHE A 313
ARG A 316
LEU A 326
ALA A 327
VAL A 342
ILE A 345
CYH A 432
HIS A 435
LEU A 436
 9CR  A 503 (-3.5A)
9CR  A 503 (-3.5A)
9CR  A 503 (-4.7A)
9CR  A 503 (-3.0A)
9CR  A 503 (-4.3A)
9CR  A 503 (-3.4A)
None
None
9CR  A 503 (-3.3A)
None
9CR  A 503 ( 4.8A)
 0.55A 1fm6U-5uanA:
33.0		 1fm6U-5uanA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FM6_U_9CRU502_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5uan RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		6 / 12 TRP A 305
VAL A 342
ILE A 345
CYH A 432
HIS A 435
LEU A 436
 None
None
None
9CR  A 503 (-3.3A)
None
9CR  A 503 ( 4.8A)
 1.16A 1fm6U-5uanA:
33.0		 1fm6U-5uanA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FM9_A_9CRA201_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xiu RXR-LIKE PROTEIN
(Biomphalaria
glabrata) 		12 / 12 ILE A 242
ALA A 245
ALA A 246
TRP A 279
LEU A 283
PHE A 287
ARG A 290
LEU A 300
ALA A 301
VAL A 316
CYH A 406
LEU A 410
 9CR  A 201 ( 4.4A)
9CR  A 201 (-3.6A)
9CR  A 201 (-3.6A)
None
9CR  A 201 ( 4.1A)
9CR  A 201 (-4.7A)
9CR  A 201 (-2.8A)
9CR  A 201 (-4.4A)
9CR  A 201 (-3.4A)
9CR  A 201 (-4.2A)
9CR  A 201 (-3.6A)
9CR  A 201 ( 4.8A)
 0.31A 1fm9A-1xiuA:
32.4		 1fm9A-1xiuA:
81.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FM9_A_9CRA201_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xls RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		12 / 12 ILE A 268
ALA A 271
ALA A 272
TRP A 305
LEU A 309
PHE A 313
ARG A 316
LEU A 326
ALA A 327
VAL A 342
CYH A 432
LEU A 436
 9CR  A 801 (-3.9A)
9CR  A 801 (-3.6A)
9CR  A 801 (-3.5A)
None
9CR  A 801 (-4.2A)
9CR  A 801 (-4.3A)
9CR  A 801 (-2.6A)
9CR  A 801 (-4.1A)
9CR  A 801 (-3.3A)
9CR  A 801 ( 4.3A)
9CR  A 801 ( 3.7A)
9CR  A 801 (-4.7A)
 0.32A 1fm9A-1xlsA:
37.5		 1fm9A-1xlsA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FM9_A_9CRA201_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		12 / 12 ILE A 268
ALA A 271
ALA A 272
TRP A 305
LEU A 309
PHE A 313
ARG A 316
LEU A 326
ALA A 327
VAL A 342
CYH A 432
LEU A 436
 9CR  A7223 (-3.9A)
9CR  A7223 (-3.5A)
9CR  A7223 (-4.2A)
None
9CR  A7223 ( 4.4A)
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
9CR  A7223 ( 4.5A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
 0.62A 1fm9A-3dzuA:
32.7		 1fm9A-3dzuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FM9_A_9CRA201_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5uan RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		12 / 12 ILE A 268
ALA A 271
ALA A 272
TRP A 305
LEU A 309
PHE A 313
ARG A 316
LEU A 326
ALA A 327
VAL A 342
CYH A 432
LEU A 436
 9CR  A 503 (-4.0A)
9CR  A 503 (-3.5A)
9CR  A 503 (-3.5A)
None
9CR  A 503 (-3.7A)
9CR  A 503 (-4.7A)
9CR  A 503 (-3.0A)
9CR  A 503 (-4.3A)
9CR  A 503 (-3.4A)
None
9CR  A 503 (-3.3A)
9CR  A 503 ( 4.8A)
 0.53A 1fm9A-5uanA:
33.1		 1fm9A-5uanA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FM9_A_9CRA201_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xiu RXR-LIKE PROTEIN
(Biomphalaria
glabrata) 		3 / 3 GLN A 249
ILE A 319
HIS A 409
 9CR  A 201 (-4.1A)
None
9CR  A 201 (-4.8A)
 0.33A 1fm9A-1xiuA:
32.4		 1fm9A-1xiuA:
81.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FM9_A_9CRA201_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xls RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		3 / 3 GLN A 275
ILE A 345
HIS A 435
 9CR  A 801 (-4.7A)
9CR  A 801 ( 4.5A)
None
 0.40A 1fm9A-1xlsA:
37.5		 1fm9A-1xlsA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FM9_A_9CRA201_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		3 / 3 GLN A 275
ILE A 345
HIS A 435
 9CR  A7223 (-4.6A)
9CR  A7223 ( 4.9A)
9CR  A7223 (-4.3A)
 0.52A 1fm9A-3dzuA:
32.7		 1fm9A-3dzuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FM9_A_9CRA201_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5uan RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		3 / 3 GLN A 275
ILE A 345
HIS A 435
 9CR  A 503 (-3.8A)
None
None
 0.39A 1fm9A-5uanA:
33.1		 1fm9A-5uanA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1G5Y_B_9CRB501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xiu RXR-LIKE PROTEIN
(Biomphalaria
glabrata) 		5 / 12 TRP A 279
LEU A 283
ARG A 290
LEU A 300
ALA A 301
 None
9CR  A 201 ( 4.1A)
9CR  A 201 (-2.8A)
9CR  A 201 (-4.4A)
9CR  A 201 (-3.4A)
 0.55A 1g5yB-1xiuA:
27.4		 1g5yB-1xiuA:
81.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1G5Y_B_9CRB501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xls RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		5 / 12 TRP A 305
LEU A 309
ARG A 316
LEU A 326
ALA A 327
 None
9CR  A 801 (-4.2A)
9CR  A 801 (-2.6A)
9CR  A 801 (-4.1A)
9CR  A 801 (-3.3A)
 0.49A 1g5yB-1xlsA:
27.5		 1g5yB-1xlsA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1G5Y_B_9CRB501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		5 / 12 TRP A 305
LEU A 309
ARG A 316
LEU A 326
ALA A 327
 None
9CR  A7223 ( 4.4A)
9CR  A7223 (-3.7A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
 0.56A 1g5yB-3dzuA:
25.5		 1g5yB-3dzuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1G5Y_C_9CRC502_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xiu RXR-LIKE PROTEIN
(Biomphalaria
glabrata) 		5 / 10 LEU A 283
PHE A 287
ARG A 290
LEU A 300
ALA A 301
 9CR  A 201 ( 4.1A)
9CR  A 201 (-4.7A)
9CR  A 201 (-2.8A)
9CR  A 201 (-4.4A)
9CR  A 201 (-3.4A)
 0.59A 1g5yC-1xiuA:
27.6		 1g5yC-1xiuA:
81.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1G5Y_C_9CRC502_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xls RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		6 / 10 LEU A 309
SER A 312
PHE A 313
ARG A 316
LEU A 326
ALA A 327
 9CR  A 801 (-4.2A)
None
9CR  A 801 (-4.3A)
9CR  A 801 (-2.6A)
9CR  A 801 (-4.1A)
9CR  A 801 (-3.3A)
 0.54A 1g5yC-1xlsA:
27.5		 1g5yC-1xlsA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1G5Y_C_9CRC502_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		6 / 10 LEU A 309
SER A 312
PHE A 313
ARG A 316
LEU A 326
ALA A 327
 9CR  A7223 ( 4.4A)
9CR  A7223 ( 4.0A)
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
 0.87A 1g5yC-3dzuA:
25.5		 1g5yC-3dzuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1G5Y_C_9CRC502_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5uan RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		6 / 10 LEU A 309
SER A 312
PHE A 313
ARG A 316
LEU A 326
ALA A 327
 9CR  A 503 (-3.7A)
None
9CR  A 503 (-4.7A)
9CR  A 503 (-3.0A)
9CR  A 503 (-4.3A)
9CR  A 503 (-3.4A)
 0.53A 1g5yC-5uanA:
25.5		 1g5yC-5uanA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_B_115B1_1
(HMG-COA REDUCTASE)		 1xls RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		5 / 9 CYH A 432
LEU A 451
ALA A 272
LEU A 276
LEU A 309
 9CR  A 801 ( 3.7A)
None
9CR  A 801 (-3.5A)
None
9CR  A 801 (-4.2A)
 1.25A 1hwiA-1xlsA:
undetectable		 1hwiA-1xlsA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J7K_A_ACTA701_0
(HOLLIDAY JUNCTION
DNA HELICASE RUVB)		 1xdk RETINOIC ACID
RECEPTOR, BETA
(Mus
musculus) 		4 / 4 GLY B 294
LEU B 391
GLY B 296
ARG B 387
 9CR  B 600 (-4.7A)
None
None
None
 1.27A 1j7kA-1xdkB:
undetectable		 1j7kA-1xdkB:
22.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1K74_A_9CRA463_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xiu RXR-LIKE PROTEIN
(Biomphalaria
glabrata) 		12 / 12 ILE A 242
ALA A 245
ALA A 246
TRP A 279
LEU A 283
PHE A 287
ARG A 290
LEU A 300
ALA A 301
VAL A 316
CYH A 406
LEU A 410
 9CR  A 201 ( 4.4A)
9CR  A 201 (-3.6A)
9CR  A 201 (-3.6A)
None
9CR  A 201 ( 4.1A)
9CR  A 201 (-4.7A)
9CR  A 201 (-2.8A)
9CR  A 201 (-4.4A)
9CR  A 201 (-3.4A)
9CR  A 201 (-4.2A)
9CR  A 201 (-3.6A)
9CR  A 201 ( 4.8A)
 0.31A 1k74A-1xiuA:
32.2		 1k74A-1xiuA:
81.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1K74_A_9CRA463_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xls RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		12 / 12 ILE A 268
ALA A 271
ALA A 272
TRP A 305
LEU A 309
PHE A 313
ARG A 316
LEU A 326
ALA A 327
VAL A 342
CYH A 432
LEU A 436
 9CR  A 801 (-3.9A)
9CR  A 801 (-3.6A)
9CR  A 801 (-3.5A)
None
9CR  A 801 (-4.2A)
9CR  A 801 (-4.3A)
9CR  A 801 (-2.6A)
9CR  A 801 (-4.1A)
9CR  A 801 (-3.3A)
9CR  A 801 ( 4.3A)
9CR  A 801 ( 3.7A)
9CR  A 801 (-4.7A)
 0.36A 1k74A-1xlsA:
37.4		 1k74A-1xlsA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1K74_A_9CRA463_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		12 / 12 ILE A 268
ALA A 271
ALA A 272
TRP A 305
LEU A 309
PHE A 313
ARG A 316
LEU A 326
ALA A 327
VAL A 342
CYH A 432
LEU A 436
 9CR  A7223 (-3.9A)
9CR  A7223 (-3.5A)
9CR  A7223 (-4.2A)
None
9CR  A7223 ( 4.4A)
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
9CR  A7223 ( 4.5A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
 0.64A 1k74A-3dzuA:
32.8		 1k74A-3dzuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1K74_A_9CRA463_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5uan RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		12 / 12 ILE A 268
ALA A 271
ALA A 272
TRP A 305
LEU A 309
PHE A 313
ARG A 316
LEU A 326
ALA A 327
VAL A 342
CYH A 432
LEU A 436
 9CR  A 503 (-4.0A)
9CR  A 503 (-3.5A)
9CR  A 503 (-3.5A)
None
9CR  A 503 (-3.7A)
9CR  A 503 (-4.7A)
9CR  A 503 (-3.0A)
9CR  A 503 (-4.3A)
9CR  A 503 (-3.4A)
None
9CR  A 503 (-3.3A)
9CR  A 503 ( 4.8A)
 0.56A 1k74A-5uanA:
33.2		 1k74A-5uanA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1K74_A_9CRA463_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xiu RXR-LIKE PROTEIN
(Biomphalaria
glabrata) 		3 / 3 GLN A 249
ILE A 319
HIS A 409
 9CR  A 201 (-4.1A)
None
9CR  A 201 (-4.8A)
 0.33A 1k74A-1xiuA:
32.2		 1k74A-1xiuA:
81.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1K74_A_9CRA463_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xls RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		3 / 3 GLN A 275
ILE A 345
HIS A 435
 9CR  A 801 (-4.7A)
9CR  A 801 ( 4.5A)
None
 0.34A 1k74A-1xlsA:
37.4		 1k74A-1xlsA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1K74_A_9CRA463_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		3 / 3 GLN A 275
ILE A 345
HIS A 435
 9CR  A7223 (-4.6A)
9CR  A7223 ( 4.9A)
9CR  A7223 (-4.3A)
 0.47A 1k74A-3dzuA:
32.8		 1k74A-3dzuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1K74_A_9CRA463_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5uan RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		3 / 3 GLN A 275
ILE A 345
HIS A 435
 9CR  A 503 (-3.8A)
None
None
 0.40A 1k74A-5uanA:
33.2		 1k74A-5uanA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PCG_A_ESTA1_1
(ESTROGEN RECEPTOR)		 1xls RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		5 / 10 ALA A 272
LEU A 309
ARG A 316
ILE A 345
LEU A 436
 9CR  A 801 (-3.5A)
9CR  A 801 (-4.2A)
9CR  A 801 (-2.6A)
9CR  A 801 ( 4.5A)
9CR  A 801 (-4.7A)
 0.99A 1pcgA-1xlsA:
25.5		 1pcgA-1xlsA:
32.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKN_A_RALA600_1
(ESTROGEN RECEPTOR
BETA)		 1xiu RXR-LIKE PROTEIN
(Biomphalaria
glabrata) 		6 / 12 ALA A 246
LEU A 283
ARG A 290
ILE A 319
ILE A 402
GLY A 403
 9CR  A 201 (-3.6A)
9CR  A 201 ( 4.1A)
9CR  A 201 (-2.8A)
None
None
None
 1.03A 1qknA-1xiuA:
23.1		 1qknA-1xiuA:
30.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1QKN_A_RALA600_1
(ESTROGEN RECEPTOR
BETA)		 1xls RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		6 / 12 ALA A 272
LEU A 309
ARG A 316
ILE A 345
ILE A 428
GLY A 429
 9CR  A 801 (-3.5A)
9CR  A 801 (-4.2A)
9CR  A 801 (-2.6A)
9CR  A 801 ( 4.5A)
None
None
 1.03A 1qknA-1xlsA:
22.4		 1qknA-1xlsA:
31.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKN_A_RALA600_1
(ESTROGEN RECEPTOR
BETA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		5 / 12 ALA A 272
LEU A 309
ARG A 316
ILE A 345
LEU A 436
 9CR  A7223 (-4.2A)
9CR  A7223 ( 4.4A)
9CR  A7223 (-3.7A)
9CR  A7223 ( 4.9A)
9CR  A7223 ( 4.7A)
 0.98A 1qknA-3dzuA:
22.6		 1qknA-3dzuA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKN_A_RALA600_1
(ESTROGEN RECEPTOR
BETA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		5 / 12 ALA A 272
LEU A 309
ARG A 316
ILE A 428
GLY A 429
 9CR  A7223 (-4.2A)
9CR  A7223 ( 4.4A)
9CR  A7223 (-3.7A)
None
None
 0.94A 1qknA-3dzuA:
22.6		 1qknA-3dzuA:
20.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1QKU_A_ESTA600_1
(ESTRADIOL RECEPTOR)		 1xls RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		5 / 10 ALA A 272
LEU A 309
ARG A 316
ILE A 345
LEU A 436
 9CR  A 801 (-3.5A)
9CR  A 801 (-4.2A)
9CR  A 801 (-2.6A)
9CR  A 801 ( 4.5A)
9CR  A 801 (-4.7A)
 0.98A 1qkuA-1xlsA:
25.4		 1qkuA-1xlsA:
31.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1QKU_B_ESTB600_1
(ESTRADIOL RECEPTOR)		 1xls RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		5 / 10 ALA A 272
LEU A 309
ARG A 316
ILE A 345
LEU A 436
 9CR  A 801 (-3.5A)
9CR  A 801 (-4.2A)
9CR  A 801 (-2.6A)
9CR  A 801 ( 4.5A)
9CR  A 801 (-4.7A)
 0.98A 1qkuB-1xlsA:
25.5		 1qkuB-1xlsA:
31.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1QKU_C_ESTC600_1
(ESTRADIOL RECEPTOR)		 1xls RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		5 / 10 ALA A 272
LEU A 309
ARG A 316
ILE A 345
LEU A 436
 9CR  A 801 (-3.5A)
9CR  A 801 (-4.2A)
9CR  A 801 (-2.6A)
9CR  A 801 ( 4.5A)
9CR  A 801 (-4.7A)
 0.98A 1qkuC-1xlsA:
25.5		 1qkuC-1xlsA:
31.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XDK_A_9CRA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xiu RXR-LIKE PROTEIN
(Biomphalaria
glabrata) 		12 / 12 ILE A 242
ALA A 245
GLN A 249
TRP A 279
ASN A 280
PHE A 287
ARG A 290
LEU A 300
ALA A 301
VAL A 316
CYH A 406
LEU A 410
 9CR  A 201 ( 4.4A)
9CR  A 201 (-3.6A)
9CR  A 201 (-4.1A)
None
None
9CR  A 201 (-4.7A)
9CR  A 201 (-2.8A)
9CR  A 201 (-4.4A)
9CR  A 201 (-3.4A)
9CR  A 201 (-4.2A)
9CR  A 201 (-3.6A)
9CR  A 201 ( 4.8A)
 0.46A 1xdkA-1xiuA:
31.6		 1xdkA-1xiuA:
81.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XDK_A_9CRA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xls RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		12 / 12 ILE A 268
ALA A 271
GLN A 275
TRP A 305
ASN A 306
PHE A 313
ARG A 316
LEU A 326
ALA A 327
VAL A 342
CYH A 432
LEU A 436
 9CR  A 801 (-3.9A)
9CR  A 801 (-3.6A)
9CR  A 801 (-4.7A)
None
None
9CR  A 801 (-4.3A)
9CR  A 801 (-2.6A)
9CR  A 801 (-4.1A)
9CR  A 801 (-3.3A)
9CR  A 801 ( 4.3A)
9CR  A 801 ( 3.7A)
9CR  A 801 (-4.7A)
 0.40A 1xdkA-1xlsA:
34.9		 1xdkA-1xlsA:
99.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XDK_A_9CRA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		10 / 12 ILE A 268
ALA A 271
GLN A 275
TRP A 305
ASN A 306
PHE A 313
ARG A 316
LEU A 326
VAL A 342
LEU A 436
 9CR  A7223 (-3.9A)
9CR  A7223 (-3.5A)
9CR  A7223 (-4.6A)
None
9CR  A7223 (-3.9A)
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.5A)
9CR  A7223 ( 4.7A)
 0.76A 1xdkA-3dzuA:
33.7		 1xdkA-3dzuA:
99.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XDK_A_9CRA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		11 / 12 ILE A 268
ALA A 271
GLN A 275
TRP A 305
PHE A 313
ARG A 316
LEU A 326
ALA A 327
VAL A 342
CYH A 432
LEU A 436
 9CR  A7223 (-3.9A)
9CR  A7223 (-3.5A)
9CR  A7223 (-4.6A)
None
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
9CR  A7223 ( 4.5A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
 0.70A 1xdkA-3dzuA:
33.7		 1xdkA-3dzuA:
99.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XDK_A_9CRA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5uan RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		12 / 12 ILE A 268
ALA A 271
GLN A 275
TRP A 305
ASN A 306
PHE A 313
ARG A 316
LEU A 326
ALA A 327
VAL A 342
CYH A 432
LEU A 436
 9CR  A 503 (-4.0A)
9CR  A 503 (-3.5A)
9CR  A 503 (-3.8A)
None
None
9CR  A 503 (-4.7A)
9CR  A 503 (-3.0A)
9CR  A 503 (-4.3A)
9CR  A 503 (-3.4A)
None
9CR  A 503 (-3.3A)
9CR  A 503 ( 4.8A)
 0.56A 1xdkA-5uanA:
34.4		 1xdkA-5uanA:
99.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XDK_E_9CRE1500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xiu RXR-LIKE PROTEIN
(Biomphalaria
glabrata) 		12 / 12 ILE A 242
ALA A 245
ALA A 246
GLN A 249
TRP A 279
PHE A 287
ARG A 290
LEU A 300
ALA A 301
VAL A 316
CYH A 406
LEU A 410
 9CR  A 201 ( 4.4A)
9CR  A 201 (-3.6A)
9CR  A 201 (-3.6A)
9CR  A 201 (-4.1A)
None
9CR  A 201 (-4.7A)
9CR  A 201 (-2.8A)
9CR  A 201 (-4.4A)
9CR  A 201 (-3.4A)
9CR  A 201 (-4.2A)
9CR  A 201 (-3.6A)
9CR  A 201 ( 4.8A)
 0.45A 1xdkE-1xiuA:
31.6		 1xdkE-1xiuA:
81.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XDK_E_9CRE1500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xls RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		12 / 12 ILE A 268
ALA A 271
ALA A 272
GLN A 275
TRP A 305
PHE A 313
ARG A 316
LEU A 326
ALA A 327
VAL A 342
CYH A 432
LEU A 436
 9CR  A 801 (-3.9A)
9CR  A 801 (-3.6A)
9CR  A 801 (-3.5A)
9CR  A 801 (-4.7A)
None
9CR  A 801 (-4.3A)
9CR  A 801 (-2.6A)
9CR  A 801 (-4.1A)
9CR  A 801 (-3.3A)
9CR  A 801 ( 4.3A)
9CR  A 801 ( 3.7A)
9CR  A 801 (-4.7A)
 0.40A 1xdkE-1xlsA:
34.9		 1xdkE-1xlsA:
99.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XDK_E_9CRE1500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		12 / 12 ILE A 268
ALA A 271
ALA A 272
GLN A 275
TRP A 305
PHE A 313
ARG A 316
LEU A 326
ALA A 327
VAL A 342
CYH A 432
LEU A 436
 9CR  A7223 (-3.9A)
9CR  A7223 (-3.5A)
9CR  A7223 (-4.2A)
9CR  A7223 (-4.6A)
None
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
9CR  A7223 ( 4.5A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
 0.67A 1xdkE-3dzuA:
33.7		 1xdkE-3dzuA:
99.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XDK_E_9CRE1500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5uan RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		12 / 12 ILE A 268
ALA A 271
ALA A 272
GLN A 275
TRP A 305
PHE A 313
ARG A 316
LEU A 326
ALA A 327
VAL A 342
CYH A 432
LEU A 436
 9CR  A 503 (-4.0A)
9CR  A 503 (-3.5A)
9CR  A 503 (-3.5A)
9CR  A 503 (-3.8A)
None
9CR  A 503 (-4.7A)
9CR  A 503 (-3.0A)
9CR  A 503 (-4.3A)
9CR  A 503 (-3.4A)
None
9CR  A 503 (-3.3A)
9CR  A 503 ( 4.8A)
 0.55A 1xdkE-5uanA:
34.4		 1xdkE-5uanA:
99.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XIU_A_9CRA201_1
(RXR-LIKE PROTEIN)		 1xls RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		12 / 12 ILE A 268
CYH A 269
ALA A 271
ALA A 272
GLN A 275
PHE A 313
ARG A 316
LEU A 326
ALA A 327
VAL A 342
CYH A 432
LEU A 436
 9CR  A 801 (-3.9A)
9CR  A 801 ( 4.5A)
9CR  A 801 (-3.6A)
9CR  A 801 (-3.5A)
9CR  A 801 (-4.7A)
9CR  A 801 (-4.3A)
9CR  A 801 (-2.6A)
9CR  A 801 (-4.1A)
9CR  A 801 (-3.3A)
9CR  A 801 ( 4.3A)
9CR  A 801 ( 3.7A)
9CR  A 801 (-4.7A)
 0.37A 1xiuA-1xlsA:
31.6		 1xiuA-1xlsA:
82.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XIU_A_9CRA201_1
(RXR-LIKE PROTEIN)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		12 / 12 ILE A 268
CYH A 269
ALA A 271
ALA A 272
GLN A 275
PHE A 313
ARG A 316
LEU A 326
ALA A 327
VAL A 342
CYH A 432
LEU A 436
 9CR  A7223 (-3.9A)
None
9CR  A7223 (-3.5A)
9CR  A7223 (-4.2A)
9CR  A7223 (-4.6A)
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
9CR  A7223 ( 4.5A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
 0.67A 1xiuA-3dzuA:
30.3		 1xiuA-3dzuA:
62.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XIU_A_9CRA201_1
(RXR-LIKE PROTEIN)		 5uan RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		12 / 12 ILE A 268
CYH A 269
ALA A 271
ALA A 272
GLN A 275
PHE A 313
ARG A 316
LEU A 326
ALA A 327
VAL A 342
CYH A 432
LEU A 436
 9CR  A 503 (-4.0A)
9CR  A 503 ( 4.4A)
9CR  A 503 (-3.5A)
9CR  A 503 (-3.5A)
9CR  A 503 (-3.8A)
9CR  A 503 (-4.7A)
9CR  A 503 (-3.0A)
9CR  A 503 (-4.3A)
9CR  A 503 (-3.4A)
None
9CR  A 503 (-3.3A)
9CR  A 503 ( 4.8A)
 0.50A 1xiuA-5uanA:
30.3		 1xiuA-5uanA:
62.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XIU_B_9CRB202_1
(RXR-LIKE PROTEIN)		 1xls RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		12 / 12 ILE A 268
ALA A 271
ALA A 272
GLN A 275
LEU A 309
PHE A 313
ARG A 316
ALA A 327
VAL A 342
CYH A 432
HIS A 435
LEU A 436
 9CR  A 801 (-3.9A)
9CR  A 801 (-3.6A)
9CR  A 801 (-3.5A)
9CR  A 801 (-4.7A)
9CR  A 801 (-4.2A)
9CR  A 801 (-4.3A)
9CR  A 801 (-2.6A)
9CR  A 801 (-3.3A)
9CR  A 801 ( 4.3A)
9CR  A 801 ( 3.7A)
None
9CR  A 801 (-4.7A)
 0.35A 1xiuB-1xlsA:
35.4		 1xiuB-1xlsA:
82.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XIU_B_9CRB202_1
(RXR-LIKE PROTEIN)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		12 / 12 ILE A 268
ALA A 271
ALA A 272
GLN A 275
LEU A 309
PHE A 313
ARG A 316
ALA A 327
VAL A 342
CYH A 432
HIS A 435
LEU A 436
 9CR  A7223 (-3.9A)
9CR  A7223 (-3.5A)
9CR  A7223 (-4.2A)
9CR  A7223 (-4.6A)
9CR  A7223 ( 4.4A)
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 ( 4.7A)
9CR  A7223 ( 4.5A)
9CR  A7223 (-3.8A)
9CR  A7223 (-4.3A)
9CR  A7223 ( 4.7A)
 0.58A 1xiuB-3dzuA:
33.1		 1xiuB-3dzuA:
62.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XIU_B_9CRB202_1
(RXR-LIKE PROTEIN)		 5uan RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		12 / 12 ILE A 268
ALA A 271
ALA A 272
GLN A 275
LEU A 309
PHE A 313
ARG A 316
ALA A 327
VAL A 342
CYH A 432
HIS A 435
LEU A 436
 9CR  A 503 (-4.0A)
9CR  A 503 (-3.5A)
9CR  A 503 (-3.5A)
9CR  A 503 (-3.8A)
9CR  A 503 (-3.7A)
9CR  A 503 (-4.7A)
9CR  A 503 (-3.0A)
9CR  A 503 (-3.4A)
None
9CR  A 503 (-3.3A)
None
9CR  A 503 ( 4.8A)
 0.58A 1xiuB-5uanA:
33.9		 1xiuB-5uanA:
62.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XLS_A_9CRA801_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xiu RXR-LIKE PROTEIN
(Biomphalaria
glabrata) 		12 / 12 ILE A 242
ALA A 245
ALA A 246
TRP A 279
LEU A 283
PHE A 287
ARG A 290
LEU A 300
ALA A 301
VAL A 316
CYH A 406
LEU A 410
 9CR  A 201 ( 4.4A)
9CR  A 201 (-3.6A)
9CR  A 201 (-3.6A)
None
9CR  A 201 ( 4.1A)
9CR  A 201 (-4.7A)
9CR  A 201 (-2.8A)
9CR  A 201 (-4.4A)
9CR  A 201 (-3.4A)
9CR  A 201 (-4.2A)
9CR  A 201 (-3.6A)
9CR  A 201 ( 4.8A)
 0.38A 1xlsA-1xiuA:
31.6		 1xlsA-1xiuA:
82.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XLS_A_9CRA801_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		12 / 12 ILE A 268
ALA A 271
ALA A 272
TRP A 305
LEU A 309
PHE A 313
ARG A 316
LEU A 326
ALA A 327
VAL A 342
CYH A 432
LEU A 436
 9CR  A7223 (-3.9A)
9CR  A7223 (-3.5A)
9CR  A7223 (-4.2A)
None
9CR  A7223 ( 4.4A)
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
9CR  A7223 ( 4.5A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
 0.64A 1xlsA-3dzuA:
32.9		 1xlsA-3dzuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XLS_A_9CRA801_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5uan RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		12 / 12 ILE A 268
ALA A 271
ALA A 272
TRP A 305
LEU A 309
PHE A 313
ARG A 316
LEU A 326
ALA A 327
VAL A 342
CYH A 432
LEU A 436
 9CR  A 503 (-4.0A)
9CR  A 503 (-3.5A)
9CR  A 503 (-3.5A)
None
9CR  A 503 (-3.7A)
9CR  A 503 (-4.7A)
9CR  A 503 (-3.0A)
9CR  A 503 (-4.3A)
9CR  A 503 (-3.4A)
None
9CR  A 503 (-3.3A)
9CR  A 503 ( 4.8A)
 0.53A 1xlsA-5uanA:
33.1		 1xlsA-5uanA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XLS_B_9CRB802_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xiu RXR-LIKE PROTEIN
(Biomphalaria
glabrata) 		12 / 12 ILE A 242
ALA A 245
ALA A 246
TRP A 279
LEU A 283
PHE A 287
ARG A 290
LEU A 300
ALA A 301
VAL A 316
CYH A 406
LEU A 410
 9CR  A 201 ( 4.4A)
9CR  A 201 (-3.6A)
9CR  A 201 (-3.6A)
None
9CR  A 201 ( 4.1A)
9CR  A 201 (-4.7A)
9CR  A 201 (-2.8A)
9CR  A 201 (-4.4A)
9CR  A 201 (-3.4A)
9CR  A 201 (-4.2A)
9CR  A 201 (-3.6A)
9CR  A 201 ( 4.8A)
 0.38A 1xlsB-1xiuA:
31.7		 1xlsB-1xiuA:
82.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XLS_B_9CRB802_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		12 / 12 ILE A 268
ALA A 271
ALA A 272
TRP A 305
LEU A 309
PHE A 313
ARG A 316
LEU A 326
ALA A 327
VAL A 342
CYH A 432
LEU A 436
 9CR  A7223 (-3.9A)
9CR  A7223 (-3.5A)
9CR  A7223 (-4.2A)
None
9CR  A7223 ( 4.4A)
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
9CR  A7223 ( 4.5A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
 0.64A 1xlsB-3dzuA:
32.9		 1xlsB-3dzuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XLS_B_9CRB802_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5uan RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		12 / 12 ILE A 268
ALA A 271
ALA A 272
TRP A 305
LEU A 309
PHE A 313
ARG A 316
LEU A 326
ALA A 327
VAL A 342
CYH A 432
LEU A 436
 9CR  A 503 (-4.0A)
9CR  A 503 (-3.5A)
9CR  A 503 (-3.5A)
None
9CR  A 503 (-3.7A)
9CR  A 503 (-4.7A)
9CR  A 503 (-3.0A)
9CR  A 503 (-4.3A)
9CR  A 503 (-3.4A)
None
9CR  A 503 (-3.3A)
9CR  A 503 ( 4.8A)
 0.53A 1xlsB-5uanA:
33.2		 1xlsB-5uanA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XLS_C_9CRC803_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xiu RXR-LIKE PROTEIN
(Biomphalaria
glabrata) 		12 / 12 ILE A 242
ALA A 245
ALA A 246
TRP A 279
LEU A 283
PHE A 287
ARG A 290
LEU A 300
ALA A 301
VAL A 316
CYH A 406
LEU A 410
 9CR  A 201 ( 4.4A)
9CR  A 201 (-3.6A)
9CR  A 201 (-3.6A)
None
9CR  A 201 ( 4.1A)
9CR  A 201 (-4.7A)
9CR  A 201 (-2.8A)
9CR  A 201 (-4.4A)
9CR  A 201 (-3.4A)
9CR  A 201 (-4.2A)
9CR  A 201 (-3.6A)
9CR  A 201 ( 4.8A)
 0.38A 1xlsC-1xiuA:
31.6		 1xlsC-1xiuA:
82.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XLS_C_9CRC803_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		12 / 12 ILE A 268
ALA A 271
ALA A 272
TRP A 305
LEU A 309
PHE A 313
ARG A 316
LEU A 326
ALA A 327
VAL A 342
CYH A 432
LEU A 436
 9CR  A7223 (-3.9A)
9CR  A7223 (-3.5A)
9CR  A7223 (-4.2A)
None
9CR  A7223 ( 4.4A)
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
9CR  A7223 ( 4.5A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
 0.64A 1xlsC-3dzuA:
32.9		 1xlsC-3dzuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XLS_C_9CRC803_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5uan RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		12 / 12 ILE A 268
ALA A 271
ALA A 272
TRP A 305
LEU A 309
PHE A 313
ARG A 316
LEU A 326
ALA A 327
VAL A 342
CYH A 432
LEU A 436
 9CR  A 503 (-4.0A)
9CR  A 503 (-3.5A)
9CR  A 503 (-3.5A)
None
9CR  A 503 (-3.7A)
9CR  A 503 (-4.7A)
9CR  A 503 (-3.0A)
9CR  A 503 (-4.3A)
9CR  A 503 (-3.4A)
None
9CR  A 503 (-3.3A)
9CR  A 503 ( 4.8A)
 0.53A 1xlsC-5uanA:
33.2		 1xlsC-5uanA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XLS_D_9CRD804_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xiu RXR-LIKE PROTEIN
(Biomphalaria
glabrata) 		12 / 12 ILE A 242
ALA A 245
ALA A 246
TRP A 279
LEU A 283
PHE A 287
ARG A 290
LEU A 300
ALA A 301
VAL A 316
CYH A 406
LEU A 410
 9CR  A 201 ( 4.4A)
9CR  A 201 (-3.6A)
9CR  A 201 (-3.6A)
None
9CR  A 201 ( 4.1A)
9CR  A 201 (-4.7A)
9CR  A 201 (-2.8A)
9CR  A 201 (-4.4A)
9CR  A 201 (-3.4A)
9CR  A 201 (-4.2A)
9CR  A 201 (-3.6A)
9CR  A 201 ( 4.8A)
 0.38A 1xlsD-1xiuA:
31.6		 1xlsD-1xiuA:
82.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XLS_D_9CRD804_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		12 / 12 ILE A 268
ALA A 271
ALA A 272
TRP A 305
LEU A 309
PHE A 313
ARG A 316
LEU A 326
ALA A 327
VAL A 342
CYH A 432
LEU A 436
 9CR  A7223 (-3.9A)
9CR  A7223 (-3.5A)
9CR  A7223 (-4.2A)
None
9CR  A7223 ( 4.4A)
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
9CR  A7223 ( 4.5A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
 0.64A 1xlsD-3dzuA:
32.9		 1xlsD-3dzuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XLS_D_9CRD804_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5uan RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		12 / 12 ILE A 268
ALA A 271
ALA A 272
TRP A 305
LEU A 309
PHE A 313
ARG A 316
LEU A 326
ALA A 327
VAL A 342
CYH A 432
LEU A 436
 9CR  A 503 (-4.0A)
9CR  A 503 (-3.5A)
9CR  A 503 (-3.5A)
None
9CR  A 503 (-3.7A)
9CR  A 503 (-4.7A)
9CR  A 503 (-3.0A)
9CR  A 503 (-4.3A)
9CR  A 503 (-3.4A)
None
9CR  A 503 (-3.3A)
9CR  A 503 ( 4.8A)
 0.53A 1xlsD-5uanA:
33.2		 1xlsD-5uanA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ACL_A_REAA502_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xiu RXR-LIKE PROTEIN
(Biomphalaria
glabrata) 		11 / 12 ALA A 245
ALA A 246
GLN A 249
ASN A 280
LEU A 283
PHE A 287
ARG A 290
LEU A 300
ALA A 301
ILE A 319
CYH A 406
 9CR  A 201 (-3.6A)
9CR  A 201 (-3.6A)
9CR  A 201 (-4.1A)
None
9CR  A 201 ( 4.1A)
9CR  A 201 (-4.7A)
9CR  A 201 (-2.8A)
9CR  A 201 (-4.4A)
9CR  A 201 (-3.4A)
None
9CR  A 201 (-3.6A)
 0.49A 2aclA-1xiuA:
30.6
2aclE-1xiuA:
30.6		 2aclA-1xiuA:
81.09
2aclE-1xiuA:
81.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ACL_A_REAA502_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xls RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		11 / 12 ALA A 271
ALA A 272
GLN A 275
ASN A 306
LEU A 309
PHE A 313
ARG A 316
LEU A 326
ALA A 327
ILE A 345
CYH A 432
 9CR  A 801 (-3.6A)
9CR  A 801 (-3.5A)
9CR  A 801 (-4.7A)
None
9CR  A 801 (-4.2A)
9CR  A 801 (-4.3A)
9CR  A 801 (-2.6A)
9CR  A 801 (-4.1A)
9CR  A 801 (-3.3A)
9CR  A 801 ( 4.5A)
9CR  A 801 ( 3.7A)
 0.47A 2aclA-1xlsA:
29.8
2aclE-1xlsA:
29.6		 2aclA-1xlsA:
100.00
2aclE-1xlsA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ACL_A_REAA502_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		10 / 12 ALA A 271
ALA A 272
GLN A 275
ASN A 306
LEU A 309
PHE A 313
ARG A 316
LEU A 326
ILE A 345
CYH A 432
 9CR  A7223 (-3.5A)
9CR  A7223 (-4.2A)
9CR  A7223 (-4.6A)
9CR  A7223 (-3.9A)
9CR  A7223 ( 4.4A)
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.9A)
9CR  A7223 (-3.8A)
 0.75A 2aclA-3dzuA:
29.9
2aclE-3dzuA:
29.9		 2aclA-3dzuA:
100.00
2aclE-3dzuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ACL_A_REAA502_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		8 / 12 GLN A 275
LEU A 309
PHE A 313
ARG A 316
LEU A 326
ALA A 327
ILE A 345
CYH A 432
 9CR  A7223 (-4.6A)
9CR  A7223 ( 4.4A)
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
9CR  A7223 ( 4.9A)
9CR  A7223 (-3.8A)
 0.73A 2aclA-3dzuA:
29.9
2aclE-3dzuA:
29.9		 2aclA-3dzuA:
100.00
2aclE-3dzuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ACL_A_REAA502_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5uan RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		11 / 12 ALA A 271
ALA A 272
GLN A 275
ASN A 306
LEU A 309
PHE A 313
ARG A 316
LEU A 326
ALA A 327
ILE A 345
CYH A 432
 9CR  A 503 (-3.5A)
9CR  A 503 (-3.5A)
9CR  A 503 (-3.8A)
None
9CR  A 503 (-3.7A)
9CR  A 503 (-4.7A)
9CR  A 503 (-3.0A)
9CR  A 503 (-4.3A)
9CR  A 503 (-3.4A)
None
9CR  A 503 (-3.3A)
 0.63A 2aclA-5uanA:
29.7
2aclE-5uanA:
29.6		 2aclA-5uanA:
100.00
2aclE-5uanA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ACL_A_REAA502_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5uan RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		7 / 12 ALA A 271
ALA A 272
PHE A 313
ARG A 316
LEU A 326
ALA A 327
ILE A 428
 9CR  A 503 (-3.5A)
9CR  A 503 (-3.5A)
9CR  A 503 (-4.7A)
9CR  A 503 (-3.0A)
9CR  A 503 (-4.3A)
9CR  A 503 (-3.4A)
None
 1.31A 2aclA-5uanA:
29.7
2aclE-5uanA:
29.6		 2aclA-5uanA:
100.00
2aclE-5uanA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ACL_C_REAC503_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xiu RXR-LIKE PROTEIN
(Biomphalaria
glabrata) 		10 / 10 ILE A 242
ALA A 245
ALA A 246
GLN A 249
ASN A 280
PHE A 287
ARG A 290
ALA A 301
ILE A 319
CYH A 406
 9CR  A 201 ( 4.4A)
9CR  A 201 (-3.6A)
9CR  A 201 (-3.6A)
9CR  A 201 (-4.1A)
None
9CR  A 201 (-4.7A)
9CR  A 201 (-2.8A)
9CR  A 201 (-3.4A)
None
9CR  A 201 (-3.6A)
 0.40A 2aclC-1xiuA:
30.9		 2aclC-1xiuA:
81.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ACL_C_REAC503_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xls RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		10 / 10 ILE A 268
ALA A 271
ALA A 272
GLN A 275
ASN A 306
PHE A 313
ARG A 316
ALA A 327
ILE A 345
CYH A 432
 9CR  A 801 (-3.9A)
9CR  A 801 (-3.6A)
9CR  A 801 (-3.5A)
9CR  A 801 (-4.7A)
None
9CR  A 801 (-4.3A)
9CR  A 801 (-2.6A)
9CR  A 801 (-3.3A)
9CR  A 801 ( 4.5A)
9CR  A 801 ( 3.7A)
 0.45A 2aclC-1xlsA:
29.8		 2aclC-1xlsA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ACL_C_REAC503_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		8 / 10 ALA A 271
ALA A 272
GLN A 275
ASN A 306
PHE A 313
ARG A 316
ILE A 345
CYH A 432
 9CR  A7223 (-3.5A)
9CR  A7223 (-4.2A)
9CR  A7223 (-4.6A)
9CR  A7223 (-3.9A)
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 ( 4.9A)
9CR  A7223 (-3.8A)
 0.77A 2aclC-3dzuA:
30.1		 2aclC-3dzuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ACL_C_REAC503_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		9 / 10 ILE A 268
ALA A 271
ALA A 272
GLN A 275
PHE A 313
ARG A 316
ALA A 327
ILE A 345
CYH A 432
 9CR  A7223 (-3.9A)
9CR  A7223 (-3.5A)
9CR  A7223 (-4.2A)
9CR  A7223 (-4.6A)
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 ( 4.7A)
9CR  A7223 ( 4.9A)
9CR  A7223 (-3.8A)
 0.81A 2aclC-3dzuA:
30.1		 2aclC-3dzuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ACL_C_REAC503_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5uan RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		6 / 10 ALA A 271
ALA A 272
PHE A 313
ARG A 316
ALA A 327
ILE A 428
 9CR  A 503 (-3.5A)
9CR  A 503 (-3.5A)
9CR  A 503 (-4.7A)
9CR  A 503 (-3.0A)
9CR  A 503 (-3.4A)
None
 1.38A 2aclC-5uanA:
29.8		 2aclC-5uanA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ACL_C_REAC503_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5uan RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		10 / 10 ILE A 268
ALA A 271
ALA A 272
GLN A 275
ASN A 306
PHE A 313
ARG A 316
ALA A 327
ILE A 345
CYH A 432
 9CR  A 503 (-4.0A)
9CR  A 503 (-3.5A)
9CR  A 503 (-3.5A)
9CR  A 503 (-3.8A)
None
9CR  A 503 (-4.7A)
9CR  A 503 (-3.0A)
9CR  A 503 (-3.4A)
None
9CR  A 503 (-3.3A)
 0.62A 2aclC-5uanA:
29.8		 2aclC-5uanA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ACL_E_REAE504_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xiu RXR-LIKE PROTEIN
(Biomphalaria
glabrata) 		11 / 11 ILE A 242
ALA A 245
ALA A 246
GLN A 249
ASN A 280
LEU A 283
PHE A 287
ARG A 290
ALA A 301
ILE A 319
CYH A 406
 9CR  A 201 ( 4.4A)
9CR  A 201 (-3.6A)
9CR  A 201 (-3.6A)
9CR  A 201 (-4.1A)
None
9CR  A 201 ( 4.1A)
9CR  A 201 (-4.7A)
9CR  A 201 (-2.8A)
9CR  A 201 (-3.4A)
None
9CR  A 201 (-3.6A)
 0.51A 2aclE-1xiuA:
30.6		 2aclE-1xiuA:
81.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ACL_E_REAE504_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xls RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		11 / 11 ILE A 268
ALA A 271
ALA A 272
GLN A 275
ASN A 306
LEU A 309
PHE A 313
ARG A 316
ALA A 327
ILE A 345
CYH A 432
 9CR  A 801 (-3.9A)
9CR  A 801 (-3.6A)
9CR  A 801 (-3.5A)
9CR  A 801 (-4.7A)
None
9CR  A 801 (-4.2A)
9CR  A 801 (-4.3A)
9CR  A 801 (-2.6A)
9CR  A 801 (-3.3A)
9CR  A 801 ( 4.5A)
9CR  A 801 ( 3.7A)
 0.58A 2aclE-1xlsA:
29.6		 2aclE-1xlsA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ACL_E_REAE504_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		9 / 11 ALA A 271
ALA A 272
GLN A 275
ASN A 306
LEU A 309
PHE A 313
ARG A 316
ILE A 345
CYH A 432
 9CR  A7223 (-3.5A)
9CR  A7223 (-4.2A)
9CR  A7223 (-4.6A)
9CR  A7223 (-3.9A)
9CR  A7223 ( 4.4A)
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 ( 4.9A)
9CR  A7223 (-3.8A)
 0.84A 2aclE-3dzuA:
29.9		 2aclE-3dzuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ACL_E_REAE504_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		10 / 11 ILE A 268
ALA A 271
ALA A 272
GLN A 275
LEU A 309
PHE A 313
ARG A 316
ALA A 327
ILE A 345
CYH A 432
 9CR  A7223 (-3.9A)
9CR  A7223 (-3.5A)
9CR  A7223 (-4.2A)
9CR  A7223 (-4.6A)
9CR  A7223 ( 4.4A)
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 ( 4.7A)
9CR  A7223 ( 4.9A)
9CR  A7223 (-3.8A)
 0.87A 2aclE-3dzuA:
29.9		 2aclE-3dzuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ACL_E_REAE504_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5uan RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		10 / 11 ILE A 268
ALA A 271
ALA A 272
ASN A 306
LEU A 309
PHE A 313
ARG A 316
ALA A 327
ILE A 345
CYH A 432
 9CR  A 503 (-4.0A)
9CR  A 503 (-3.5A)
9CR  A 503 (-3.5A)
None
9CR  A 503 (-3.7A)
9CR  A 503 (-4.7A)
9CR  A 503 (-3.0A)
9CR  A 503 (-3.4A)
None
9CR  A 503 (-3.3A)
 0.69A 2aclE-5uanA:
29.6		 2aclE-5uanA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ACL_E_REAE504_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5uan RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		10 / 11 ILE A 268
ALA A 271
ALA A 272
GLN A 275
ASN A 306
LEU A 309
PHE A 313
ARG A 316
ALA A 327
ILE A 345
 9CR  A 503 (-4.0A)
9CR  A 503 (-3.5A)
9CR  A 503 (-3.5A)
9CR  A 503 (-3.8A)
None
9CR  A 503 (-3.7A)
9CR  A 503 (-4.7A)
9CR  A 503 (-3.0A)
9CR  A 503 (-3.4A)
None
 0.65A 2aclE-5uanA:
29.6		 2aclE-5uanA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ACL_G_REAG501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xiu RXR-LIKE PROTEIN
(Biomphalaria
glabrata) 		10 / 12 ALA A 245
ALA A 246
GLN A 249
ASN A 280
LEU A 283
ILE A 284
PHE A 287
ARG A 290
ALA A 301
CYH A 406
 9CR  A 201 (-3.6A)
9CR  A 201 (-3.6A)
9CR  A 201 (-4.1A)
None
9CR  A 201 ( 4.1A)
None
9CR  A 201 (-4.7A)
9CR  A 201 (-2.8A)
9CR  A 201 (-3.4A)
9CR  A 201 (-3.6A)
 0.78A 2aclG-1xiuA:
29.7		 2aclG-1xiuA:
81.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ACL_G_REAG501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xiu RXR-LIKE PROTEIN
(Biomphalaria
glabrata) 		11 / 12 ILE A 242
ALA A 245
ALA A 246
GLN A 249
LEU A 283
ILE A 284
PHE A 287
ARG A 290
LEU A 300
ALA A 301
CYH A 406
 9CR  A 201 ( 4.4A)
9CR  A 201 (-3.6A)
9CR  A 201 (-3.6A)
9CR  A 201 (-4.1A)
9CR  A 201 ( 4.1A)
None
9CR  A 201 (-4.7A)
9CR  A 201 (-2.8A)
9CR  A 201 (-4.4A)
9CR  A 201 (-3.4A)
9CR  A 201 (-3.6A)
 0.57A 2aclG-1xiuA:
29.7		 2aclG-1xiuA:
81.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ACL_G_REAG501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xls RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		12 / 12 ILE A 268
ALA A 271
ALA A 272
GLN A 275
ASN A 306
LEU A 309
ILE A 310
PHE A 313
ARG A 316
LEU A 326
ALA A 327
CYH A 432
 9CR  A 801 (-3.9A)
9CR  A 801 (-3.6A)
9CR  A 801 (-3.5A)
9CR  A 801 (-4.7A)
None
9CR  A 801 (-4.2A)
None
9CR  A 801 (-4.3A)
9CR  A 801 (-2.6A)
9CR  A 801 (-4.1A)
9CR  A 801 (-3.3A)
9CR  A 801 ( 3.7A)
 0.78A 2aclG-1xlsA:
28.7		 2aclG-1xlsA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ACL_G_REAG501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		12 / 12 ILE A 268
ALA A 271
ALA A 272
GLN A 275
ASN A 306
LEU A 309
ILE A 310
PHE A 313
ARG A 316
LEU A 326
ALA A 327
CYH A 432
 9CR  A7223 (-3.9A)
9CR  A7223 (-3.5A)
9CR  A7223 (-4.2A)
9CR  A7223 (-4.6A)
9CR  A7223 (-3.9A)
9CR  A7223 ( 4.4A)
None
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
9CR  A7223 (-3.8A)
 0.86A 2aclG-3dzuA:
29.0		 2aclG-3dzuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ACL_G_REAG501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5uan RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		11 / 12 ILE A 268
ALA A 271
ALA A 272
ASN A 306
LEU A 309
ILE A 310
PHE A 313
ARG A 316
LEU A 326
ALA A 327
CYH A 432
 9CR  A 503 (-4.0A)
9CR  A 503 (-3.5A)
9CR  A 503 (-3.5A)
None
9CR  A 503 (-3.7A)
9CR  A 503 ( 4.8A)
9CR  A 503 (-4.7A)
9CR  A 503 (-3.0A)
9CR  A 503 (-4.3A)
9CR  A 503 (-3.4A)
9CR  A 503 (-3.3A)
 0.87A 2aclG-5uanA:
28.7		 2aclG-5uanA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ACL_G_REAG501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5uan RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		10 / 12 ILE A 268
ALA A 271
ALA A 272
GLN A 275
ASN A 306
LEU A 309
ILE A 310
PHE A 313
LEU A 326
ALA A 327
 9CR  A 503 (-4.0A)
9CR  A 503 (-3.5A)
9CR  A 503 (-3.5A)
9CR  A 503 (-3.8A)
None
9CR  A 503 (-3.7A)
9CR  A 503 ( 4.8A)
9CR  A 503 (-4.7A)
9CR  A 503 (-4.3A)
9CR  A 503 (-3.4A)
 0.68A 2aclG-5uanA:
28.7		 2aclG-5uanA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J0D_A_ERYA1498_0
(CYTOCHROME P450 3A4)		 1xls RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		5 / 12 ARG A 371
ILE A 428
ILE A 345
PHE A 346
ALA A 272
 None
None
9CR  A 801 ( 4.5A)
None
9CR  A 801 (-3.5A)
 1.04A 2j0dA-1xlsA:
undetectable		 2j0dA-1xlsA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J0D_A_ERYA1498_0
(CYTOCHROME P450 3A4)		 5uan RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		5 / 12 ARG A 371
ILE A 428
ILE A 345
PHE A 346
ALA A 272
 None
None
None
None
9CR  A 503 (-3.5A)
 1.17A 2j0dA-5uanA:
undetectable		 2j0dA-5uanA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_A_RALA600_1
(ESTROGEN RECEPTOR)		 1xiu RXR-LIKE PROTEIN
(Biomphalaria
glabrata) 		6 / 12 ALA A 246
LEU A 250
TRP A 279
LEU A 283
ARG A 290
ILE A 402
 9CR  A 201 (-3.6A)
None
None
9CR  A 201 ( 4.1A)
9CR  A 201 (-2.8A)
None
 1.04A 2jfaA-1xiuA:
23.3		 2jfaA-1xiuA:
27.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_A_RALA600_1
(ESTROGEN RECEPTOR)		 1xiu RXR-LIKE PROTEIN
(Biomphalaria
glabrata) 		5 / 12 ALA A 246
LEU A 250
TRP A 279
LEU A 283
ILE A 319
 9CR  A 201 (-3.6A)
None
None
9CR  A 201 ( 4.1A)
None
 1.02A 2jfaA-1xiuA:
23.3		 2jfaA-1xiuA:
27.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_A_RALA600_1
(ESTROGEN RECEPTOR)		 1xiu RXR-LIKE PROTEIN
(Biomphalaria
glabrata) 		5 / 12 ALA A 246
TRP A 279
LEU A 283
ARG A 290
LEU A 410
 9CR  A 201 (-3.6A)
None
9CR  A 201 ( 4.1A)
9CR  A 201 (-2.8A)
9CR  A 201 ( 4.8A)
 0.83A 2jfaA-1xiuA:
23.3		 2jfaA-1xiuA:
27.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_A_RALA600_1
(ESTROGEN RECEPTOR)		 1xiu RXR-LIKE PROTEIN
(Biomphalaria
glabrata) 		5 / 12 ALA A 246
TRP A 279
LEU A 283
ILE A 319
LEU A 410
 9CR  A 201 (-3.6A)
None
9CR  A 201 ( 4.1A)
None
9CR  A 201 ( 4.8A)
 0.89A 2jfaA-1xiuA:
23.3		 2jfaA-1xiuA:
27.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_A_RALA600_1
(ESTROGEN RECEPTOR)		 1xls RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		5 / 12 ALA A 272
LEU A 276
TRP A 305
ARG A 316
ILE A 345
 9CR  A 801 (-3.5A)
None
None
9CR  A 801 (-2.6A)
9CR  A 801 ( 4.5A)
 0.99A 2jfaA-1xlsA:
22.6		 2jfaA-1xlsA:
26.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_A_RALA600_1
(ESTROGEN RECEPTOR)		 1xls RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		5 / 12 ALA A 272
TRP A 305
ARG A 316
ILE A 345
LEU A 436
 9CR  A 801 (-3.5A)
None
9CR  A 801 (-2.6A)
9CR  A 801 ( 4.5A)
9CR  A 801 (-4.7A)
 0.91A 2jfaA-1xlsA:
22.6		 2jfaA-1xlsA:
26.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_A_RALA600_1
(ESTROGEN RECEPTOR)		 1xls RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		5 / 12 ALA A 272
TRP A 305
LEU A 309
ARG A 316
LEU A 436
 9CR  A 801 (-3.5A)
None
9CR  A 801 (-4.2A)
9CR  A 801 (-2.6A)
9CR  A 801 (-4.7A)
 0.86A 2jfaA-1xlsA:
22.6		 2jfaA-1xlsA:
26.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_A_RALA600_1
(ESTROGEN RECEPTOR)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		5 / 12 ALA A 272
LEU A 276
TRP A 305
ILE A 345
LEU A 436
 9CR  A7223 (-4.2A)
None
None
9CR  A7223 ( 4.9A)
9CR  A7223 ( 4.7A)
 0.85A 2jfaA-3dzuA:
22.7		 2jfaA-3dzuA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_A_RALA600_1
(ESTROGEN RECEPTOR)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		6 / 12 ALA A 272
LEU A 276
TRP A 305
LEU A 309
ARG A 316
ILE A 428
 9CR  A7223 (-4.2A)
None
None
9CR  A7223 ( 4.4A)
9CR  A7223 (-3.7A)
None
 1.02A 2jfaA-3dzuA:
22.7		 2jfaA-3dzuA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_A_RALA600_1
(ESTROGEN RECEPTOR)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		6 / 12 ALA A 272
LEU A 276
TRP A 305
LEU A 309
ARG A 316
LEU A 436
 9CR  A7223 (-4.2A)
None
None
9CR  A7223 ( 4.4A)
9CR  A7223 (-3.7A)
9CR  A7223 ( 4.7A)
 0.87A 2jfaA-3dzuA:
22.7		 2jfaA-3dzuA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_A_RALA600_1
(ESTROGEN RECEPTOR)		 5uan RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		6 / 12 ALA A 272
LEU A 276
TRP A 305
LEU A 309
ARG A 316
ILE A 428
 9CR  A 503 (-3.5A)
None
None
9CR  A 503 (-3.7A)
9CR  A 503 (-3.0A)
None
 1.20A 2jfaA-5uanA:
22.4		 2jfaA-5uanA:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_A_RALA600_1
(ESTROGEN RECEPTOR)		 5uan RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		5 / 12 ALA A 272
TRP A 305
LEU A 309
ARG A 316
LEU A 436
 9CR  A 503 (-3.5A)
None
9CR  A 503 (-3.7A)
9CR  A 503 (-3.0A)
9CR  A 503 ( 4.8A)
 1.03A 2jfaA-5uanA:
22.4		 2jfaA-5uanA:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_B_RALB600_1
(ESTROGEN RECEPTOR)		 1xiu RXR-LIKE PROTEIN
(Biomphalaria
glabrata) 		5 / 12 ALA A 246
ASP A 247
LEU A 283
ARG A 290
LEU A 410
 9CR  A 201 (-3.6A)
None
9CR  A 201 ( 4.1A)
9CR  A 201 (-2.8A)
9CR  A 201 ( 4.8A)
 1.09A 2jfaB-1xiuA:
22.9		 2jfaB-1xiuA:
27.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_B_RALB600_1
(ESTROGEN RECEPTOR)		 1xiu RXR-LIKE PROTEIN
(Biomphalaria
glabrata) 		6 / 12 ALA A 246
LEU A 250
TRP A 279
LEU A 283
ARG A 290
GLY A 403
 9CR  A 201 (-3.6A)
None
None
9CR  A 201 ( 4.1A)
9CR  A 201 (-2.8A)
None
 0.89A 2jfaB-1xiuA:
22.9		 2jfaB-1xiuA:
27.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_B_RALB600_1
(ESTROGEN RECEPTOR)		 1xiu RXR-LIKE PROTEIN
(Biomphalaria
glabrata) 		5 / 12 ALA A 246
TRP A 279
LEU A 283
ARG A 290
LEU A 410
 9CR  A 201 (-3.6A)
None
9CR  A 201 ( 4.1A)
9CR  A 201 (-2.8A)
9CR  A 201 ( 4.8A)
 0.82A 2jfaB-1xiuA:
22.9		 2jfaB-1xiuA:
27.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_B_RALB600_1
(ESTROGEN RECEPTOR)		 1xls RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		5 / 12 ALA A 272
LEU A 276
TRP A 305
ARG A 316
GLY A 429
 9CR  A 801 (-3.5A)
None
None
9CR  A 801 (-2.6A)
None
 0.97A 2jfaB-1xlsA:
22.6		 2jfaB-1xlsA:
26.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_B_RALB600_1
(ESTROGEN RECEPTOR)		 1xls RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		5 / 12 ALA A 272
TRP A 305
LEU A 309
ARG A 316
GLY A 429
 9CR  A 801 (-3.5A)
None
9CR  A 801 (-4.2A)
9CR  A 801 (-2.6A)
None
 0.95A 2jfaB-1xlsA:
22.6		 2jfaB-1xlsA:
26.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_B_RALB600_1
(ESTROGEN RECEPTOR)		 1xls RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		5 / 12 ALA A 272
TRP A 305
LEU A 309
ARG A 316
LEU A 436
 9CR  A 801 (-3.5A)
None
9CR  A 801 (-4.2A)
9CR  A 801 (-2.6A)
9CR  A 801 (-4.7A)
 0.85A 2jfaB-1xlsA:
22.6		 2jfaB-1xlsA:
26.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_B_RALB600_1
(ESTROGEN RECEPTOR)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		6 / 12 ALA A 272
LEU A 276
TRP A 305
LEU A 309
ARG A 316
GLY A 429
 9CR  A7223 (-4.2A)
None
None
9CR  A7223 ( 4.4A)
9CR  A7223 (-3.7A)
None
 0.88A 2jfaB-3dzuA:
22.3		 2jfaB-3dzuA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_B_RALB600_1
(ESTROGEN RECEPTOR)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		6 / 12 ALA A 272
LEU A 276
TRP A 305
LEU A 309
ARG A 316
LEU A 436
 9CR  A7223 (-4.2A)
None
None
9CR  A7223 ( 4.4A)
9CR  A7223 (-3.7A)
9CR  A7223 ( 4.7A)
 0.87A 2jfaB-3dzuA:
22.3		 2jfaB-3dzuA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_B_RALB600_1
(ESTROGEN RECEPTOR)		 5uan RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		6 / 12 ALA A 272
LEU A 276
TRP A 305
LEU A 309
ARG A 316
GLY A 429
 9CR  A 503 (-3.5A)
None
None
9CR  A 503 (-3.7A)
9CR  A 503 (-3.0A)
None
 1.05A 2jfaB-5uanA:
9.8		 2jfaB-5uanA:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_B_RALB600_1
(ESTROGEN RECEPTOR)		 5uan RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		5 / 12 ALA A 272
TRP A 305
LEU A 309
ARG A 316
LEU A 436
 9CR  A 503 (-3.5A)
None
9CR  A 503 (-3.7A)
9CR  A 503 (-3.0A)
9CR  A 503 ( 4.8A)
 1.03A 2jfaB-5uanA:
9.8		 2jfaB-5uanA:
23.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2LBD_A_REAA500_1
(RETINOIC ACID
RECEPTOR GAMMA)		 1xdk RETINOIC ACID
RECEPTOR, BETA
(Mus
musculus) 		10 / 12 PHE B 221
CYH B 228
LEU B 262
ARG B 265
ILE B 266
ARG B 269
PHE B 279
SER B 280
GLY B 384
LEU B 391
 9CR  B 600 ( 4.7A)
9CR  B 600 (-3.4A)
9CR  B 600 (-3.9A)
None
9CR  B 600 ( 3.8A)
9CR  B 600 (-3.8A)
9CR  B 600 (-4.5A)
9CR  B 600 (-3.0A)
9CR  B 600 ( 4.6A)
None
 0.55A 2lbdA-1xdkB:
37.7		 2lbdA-1xdkB:
79.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2LBD_A_REAA500_1
(RETINOIC ACID
RECEPTOR GAMMA)		 1xdk RETINOIC ACID
RECEPTOR, BETA
(Mus
musculus) 		6 / 12 PHE B 221
LYS B 227
LEU B 262
PHE B 279
GLY B 384
LEU B 391
 9CR  B 600 ( 4.7A)
None
9CR  B 600 (-3.9A)
9CR  B 600 (-4.5A)
9CR  B 600 ( 4.6A)
None
 1.07A 2lbdA-1xdkB:
37.7		 2lbdA-1xdkB:
79.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QXS_A_RALA600_1
(ESTROGEN RECEPTOR)		 1xiu RXR-LIKE PROTEIN
(Biomphalaria
glabrata) 		6 / 12 ALA A 246
LEU A 250
TRP A 279
LEU A 283
ARG A 290
ILE A 319
 9CR  A 201 (-3.6A)
None
None
9CR  A 201 ( 4.1A)
9CR  A 201 (-2.8A)
None
 1.13A 2qxsA-1xiuA:
22.9		 2qxsA-1xiuA:
29.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QXS_A_RALA600_1
(ESTROGEN RECEPTOR)		 1xiu RXR-LIKE PROTEIN
(Biomphalaria
glabrata) 		6 / 12 ALA A 246
LEU A 250
TRP A 279
LEU A 283
ARG A 290
ILE A 402
 9CR  A 201 (-3.6A)
None
None
9CR  A 201 ( 4.1A)
9CR  A 201 (-2.8A)
None
 1.07A 2qxsA-1xiuA:
22.9		 2qxsA-1xiuA:
29.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QXS_A_RALA600_1
(ESTROGEN RECEPTOR)		 1xiu RXR-LIKE PROTEIN
(Biomphalaria
glabrata) 		6 / 12 ALA A 246
TRP A 279
LEU A 283
ARG A 290
ILE A 319
LEU A 410
 9CR  A 201 (-3.6A)
None
9CR  A 201 ( 4.1A)
9CR  A 201 (-2.8A)
None
9CR  A 201 ( 4.8A)
 1.00A 2qxsA-1xiuA:
22.9		 2qxsA-1xiuA:
29.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QXS_A_RALA600_1
(ESTROGEN RECEPTOR)		 1xls RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		5 / 12 ALA A 272
LEU A 276
TRP A 305
ARG A 316
ILE A 345
 9CR  A 801 (-3.5A)
None
None
9CR  A 801 (-2.6A)
9CR  A 801 ( 4.5A)
 1.02A 2qxsA-1xlsA:
23.0		 2qxsA-1xlsA:
31.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QXS_A_RALA600_1
(ESTROGEN RECEPTOR)		 1xls RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		6 / 12 ALA A 272
TRP A 305
LEU A 309
ARG A 316
ILE A 345
LEU A 436
 9CR  A 801 (-3.5A)
None
9CR  A 801 (-4.2A)
9CR  A 801 (-2.6A)
9CR  A 801 ( 4.5A)
9CR  A 801 (-4.7A)
 0.95A 2qxsA-1xlsA:
23.0		 2qxsA-1xlsA:
31.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QXS_A_RALA600_1
(ESTROGEN RECEPTOR)		 1xls RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		5 / 12 ALA A 272
TRP A 305
LEU A 309
ARG A 316
ILE A 428
 9CR  A 801 (-3.5A)
None
9CR  A 801 (-4.2A)
9CR  A 801 (-2.6A)
None
 1.09A 2qxsA-1xlsA:
23.0		 2qxsA-1xlsA:
31.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QXS_A_RALA600_1
(ESTROGEN RECEPTOR)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		6 / 12 ALA A 272
LEU A 276
TRP A 305
LEU A 309
ARG A 316
ILE A 428
 9CR  A7223 (-4.2A)
None
None
9CR  A7223 ( 4.4A)
9CR  A7223 (-3.7A)
None
 0.99A 2qxsA-3dzuA:
22.9		 2qxsA-3dzuA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QXS_A_RALA600_1
(ESTROGEN RECEPTOR)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		5 / 12 ALA A 272
TRP A 305
LEU A 309
ARG A 316
LEU A 436
 9CR  A7223 (-4.2A)
None
9CR  A7223 ( 4.4A)
9CR  A7223 (-3.7A)
9CR  A7223 ( 4.7A)
 0.80A 2qxsA-3dzuA:
22.9		 2qxsA-3dzuA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QXS_A_RALA600_1
(ESTROGEN RECEPTOR)		 5uan RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		6 / 12 ALA A 272
LEU A 276
TRP A 305
LEU A 309
ARG A 316
ILE A 428
 9CR  A 503 (-3.5A)
None
None
9CR  A 503 (-3.7A)
9CR  A 503 (-3.0A)
None
 1.20A 2qxsA-5uanA:
22.3		 2qxsA-5uanA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QXS_B_RALB600_1
(ESTROGEN RECEPTOR)		 1xiu RXR-LIKE PROTEIN
(Biomphalaria
glabrata) 		6 / 12 ALA A 246
LEU A 250
TRP A 279
LEU A 283
ARG A 290
ILE A 402
 9CR  A 201 (-3.6A)
None
None
9CR  A 201 ( 4.1A)
9CR  A 201 (-2.8A)
None
 1.07A 2qxsB-1xiuA:
22.8		 2qxsB-1xiuA:
29.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QXS_B_RALB600_1
(ESTROGEN RECEPTOR)		 1xiu RXR-LIKE PROTEIN
(Biomphalaria
glabrata) 		5 / 12 ALA A 246
LEU A 250
TRP A 279
LEU A 283
ILE A 319
 9CR  A 201 (-3.6A)
None
None
9CR  A 201 ( 4.1A)
None
 1.06A 2qxsB-1xiuA:
22.8		 2qxsB-1xiuA:
29.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QXS_B_RALB600_1
(ESTROGEN RECEPTOR)		 1xiu RXR-LIKE PROTEIN
(Biomphalaria
glabrata) 		5 / 12 ALA A 246
TRP A 279
LEU A 283
ARG A 290
LEU A 410
 9CR  A 201 (-3.6A)
None
9CR  A 201 ( 4.1A)
9CR  A 201 (-2.8A)
9CR  A 201 ( 4.8A)
 0.94A 2qxsB-1xiuA:
22.8		 2qxsB-1xiuA:
29.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QXS_B_RALB600_1
(ESTROGEN RECEPTOR)		 1xls RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		5 / 12 ALA A 272
LEU A 276
TRP A 305
ARG A 316
ILE A 345
 9CR  A 801 (-3.5A)
None
None
9CR  A 801 (-2.6A)
9CR  A 801 ( 4.5A)
 1.03A 2qxsB-1xlsA:
22.5		 2qxsB-1xlsA:
31.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QXS_B_RALB600_1
(ESTROGEN RECEPTOR)		 1xls RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		6 / 12 ALA A 272
TRP A 305
LEU A 309
ARG A 316
ILE A 345
LEU A 436
 9CR  A 801 (-3.5A)
None
9CR  A 801 (-4.2A)
9CR  A 801 (-2.6A)
9CR  A 801 ( 4.5A)
9CR  A 801 (-4.7A)
 0.98A 2qxsB-1xlsA:
22.5		 2qxsB-1xlsA:
31.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QXS_B_RALB600_1
(ESTROGEN RECEPTOR)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		6 / 12 ALA A 272
LEU A 276
TRP A 305
LEU A 309
ARG A 316
ILE A 428
 9CR  A7223 (-4.2A)
None
None
9CR  A7223 ( 4.4A)
9CR  A7223 (-3.7A)
None
 1.01A 2qxsB-3dzuA:
22.8		 2qxsB-3dzuA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QXS_B_RALB600_1
(ESTROGEN RECEPTOR)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		5 / 12 ALA A 272
TRP A 305
LEU A 309
ARG A 316
LEU A 436
 9CR  A7223 (-4.2A)
None
9CR  A7223 ( 4.4A)
9CR  A7223 (-3.7A)
9CR  A7223 ( 4.7A)
 0.83A 2qxsB-3dzuA:
22.8		 2qxsB-3dzuA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QXS_B_RALB600_1
(ESTROGEN RECEPTOR)		 5uan RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		6 / 12 ALA A 272
LEU A 276
TRP A 305
LEU A 309
ARG A 316
ILE A 428
 9CR  A 503 (-3.5A)
None
None
9CR  A 503 (-3.7A)
9CR  A 503 (-3.0A)
None
 1.21A 2qxsB-5uanA:
22.3		 2qxsB-5uanA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YJA_B_ESTB1550_1
(ESTROGEN RECEPTOR)		 1xiu RXR-LIKE PROTEIN
(Biomphalaria
glabrata) 		5 / 12 ALA A 246
LEU A 283
ARG A 290
ILE A 402
GLY A 403
 9CR  A 201 (-3.6A)
9CR  A 201 ( 4.1A)
9CR  A 201 (-2.8A)
None
None
 0.99A 2yjaB-1xiuA:
23.1		 2yjaB-1xiuA:
29.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2YJA_B_ESTB1550_1
(ESTROGEN RECEPTOR)		 1xls RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		5 / 12 ALA A 272
LEU A 309
ARG A 316
ILE A 345
LEU A 436
 9CR  A 801 (-3.5A)
9CR  A 801 (-4.2A)
9CR  A 801 (-2.6A)
9CR  A 801 ( 4.5A)
9CR  A 801 (-4.7A)
 1.03A 2yjaB-1xlsA:
25.9		 2yjaB-1xlsA:
31.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2YJA_B_ESTB1550_1
(ESTROGEN RECEPTOR)		 1xls RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		5 / 12 ALA A 272
LEU A 309
ARG A 316
ILE A 428
GLY A 429
 9CR  A 801 (-3.5A)
9CR  A 801 (-4.2A)
9CR  A 801 (-2.6A)
None
None
 1.05A 2yjaB-1xlsA:
25.9		 2yjaB-1xlsA:
31.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3A9E_B_REAB1_1
(RETINOIC ACID
RECEPTOR ALPHA)		 1xdk RETINOIC ACID
RECEPTOR, BETA
(Mus
musculus) 		5 / 11 ILE B 266
ARG B 269
PHE B 279
SER B 280
LEU B 213
 9CR  B 600 ( 3.8A)
9CR  B 600 (-3.8A)
9CR  B 600 (-4.5A)
9CR  B 600 (-3.0A)
None
 1.35A 3a9eB-1xdkB:
37.9		 3a9eB-1xdkB:
77.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3A9E_B_REAB1_1
(RETINOIC ACID
RECEPTOR ALPHA)		 1xdk RETINOIC ACID
RECEPTOR, BETA
(Mus
musculus) 		10 / 11 PHE B 221
CYH B 228
LEU B 262
ILE B 266
ARG B 269
PHE B 279
SER B 280
PHE B 295
VAL B 388
LEU B 391
 9CR  B 600 ( 4.7A)
9CR  B 600 (-3.4A)
9CR  B 600 (-3.9A)
9CR  B 600 ( 3.8A)
9CR  B 600 (-3.8A)
9CR  B 600 (-4.5A)
9CR  B 600 (-3.0A)
9CR  B 600 (-3.9A)
9CR  B 600 ( 4.6A)
None
 0.42A 3a9eB-1xdkB:
37.9		 3a9eB-1xdkB:
77.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DZU_A_9CRA7223_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xiu RXR-LIKE PROTEIN
(Biomphalaria
glabrata) 		10 / 12 ALA A 245
GLN A 249
ASN A 280
ILE A 284
PHE A 287
ARG A 290
LEU A 300
VAL A 316
HIS A 409
LEU A 410
 9CR  A 201 (-3.6A)
9CR  A 201 (-4.1A)
None
None
9CR  A 201 (-4.7A)
9CR  A 201 (-2.8A)
9CR  A 201 (-4.4A)
9CR  A 201 (-4.2A)
9CR  A 201 (-4.8A)
9CR  A 201 ( 4.8A)
 0.69A 3dzuA-1xiuA:
30.3		 3dzuA-1xiuA:
62.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DZU_A_9CRA7223_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xiu RXR-LIKE PROTEIN
(Biomphalaria
glabrata) 		11 / 12 ILE A 242
ALA A 245
GLN A 249
ILE A 284
PHE A 287
ARG A 290
LEU A 300
VAL A 316
CYH A 406
HIS A 409
LEU A 410
 9CR  A 201 ( 4.4A)
9CR  A 201 (-3.6A)
9CR  A 201 (-4.1A)
None
9CR  A 201 (-4.7A)
9CR  A 201 (-2.8A)
9CR  A 201 (-4.4A)
9CR  A 201 (-4.2A)
9CR  A 201 (-3.6A)
9CR  A 201 (-4.8A)
9CR  A 201 ( 4.8A)
 0.53A 3dzuA-1xiuA:
30.3		 3dzuA-1xiuA:
62.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DZU_A_9CRA7223_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xls RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		11 / 12 ALA A 271
GLN A 275
ASN A 306
ILE A 310
PHE A 313
ARG A 316
LEU A 326
VAL A 342
CYH A 432
HIS A 435
LEU A 436
 9CR  A 801 (-3.6A)
9CR  A 801 (-4.7A)
None
None
9CR  A 801 (-4.3A)
9CR  A 801 (-2.6A)
9CR  A 801 (-4.1A)
9CR  A 801 ( 4.3A)
9CR  A 801 ( 3.7A)
None
9CR  A 801 (-4.7A)
 0.64A 3dzuA-1xlsA:
32.9		 3dzuA-1xlsA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DZU_A_9CRA7223_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xls RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		11 / 12 ILE A 268
ALA A 271
GLN A 275
ILE A 310
PHE A 313
ARG A 316
LEU A 326
VAL A 342
CYH A 432
HIS A 435
LEU A 436
 9CR  A 801 (-3.9A)
9CR  A 801 (-3.6A)
9CR  A 801 (-4.7A)
None
9CR  A 801 (-4.3A)
9CR  A 801 (-2.6A)
9CR  A 801 (-4.1A)
9CR  A 801 ( 4.3A)
9CR  A 801 ( 3.7A)
None
9CR  A 801 (-4.7A)
 0.51A 3dzuA-1xlsA:
32.9		 3dzuA-1xlsA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DZU_A_9CRA7223_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5uan RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		9 / 12 ALA A 271
GLN A 275
ASN A 306
ILE A 310
PHE A 313
ARG A 316
LEU A 326
VAL A 342
CYH A 432
 9CR  A 503 (-3.5A)
9CR  A 503 (-3.8A)
None
9CR  A 503 ( 4.8A)
9CR  A 503 (-4.7A)
9CR  A 503 (-3.0A)
9CR  A 503 (-4.3A)
None
9CR  A 503 (-3.3A)
 0.84A 3dzuA-5uanA:
32.9		 3dzuA-5uanA:
78.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DZU_A_9CRA7223_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5uan RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		11 / 12 ILE A 268
ALA A 271
GLN A 275
ILE A 310
PHE A 313
ARG A 316
LEU A 326
VAL A 342
CYH A 432
HIS A 435
LEU A 436
 9CR  A 503 (-4.0A)
9CR  A 503 (-3.5A)
9CR  A 503 (-3.8A)
9CR  A 503 ( 4.8A)
9CR  A 503 (-4.7A)
9CR  A 503 (-3.0A)
9CR  A 503 (-4.3A)
None
9CR  A 503 (-3.3A)
None
9CR  A 503 ( 4.8A)
 0.71A 3dzuA-5uanA:
32.9		 3dzuA-5uanA:
78.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DZY_A_9CRA463_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xiu RXR-LIKE PROTEIN
(Biomphalaria
glabrata) 		11 / 12 ILE A 242
ALA A 245
GLN A 249
ASN A 280
PHE A 287
ARG A 290
LEU A 300
ALA A 301
VAL A 316
CYH A 406
LEU A 410
 9CR  A 201 ( 4.4A)
9CR  A 201 (-3.6A)
9CR  A 201 (-4.1A)
None
9CR  A 201 (-4.7A)
9CR  A 201 (-2.8A)
9CR  A 201 (-4.4A)
9CR  A 201 (-3.4A)
9CR  A 201 (-4.2A)
9CR  A 201 (-3.6A)
9CR  A 201 ( 4.8A)
 0.65A 3dzyA-1xiuA:
29.1		 3dzyA-1xiuA:
62.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DZY_A_9CRA463_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xls RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		6 / 12 ALA A 271
GLN A 275
ASN A 306
ARG A 316
ALA A 327
LEU A 455
 9CR  A 801 (-3.6A)
9CR  A 801 (-4.7A)
None
9CR  A 801 (-2.6A)
9CR  A 801 (-3.3A)
None
 1.31A 3dzyA-1xlsA:
31.0		 3dzyA-1xlsA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DZY_A_9CRA463_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xls RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		11 / 12 ILE A 268
ALA A 271
GLN A 275
ASN A 306
PHE A 313
ARG A 316
LEU A 326
ALA A 327
VAL A 342
CYH A 432
LEU A 436
 9CR  A 801 (-3.9A)
9CR  A 801 (-3.6A)
9CR  A 801 (-4.7A)
None
9CR  A 801 (-4.3A)
9CR  A 801 (-2.6A)
9CR  A 801 (-4.1A)
9CR  A 801 (-3.3A)
9CR  A 801 ( 4.3A)
9CR  A 801 ( 3.7A)
9CR  A 801 (-4.7A)
 0.66A 3dzyA-1xlsA:
31.0		 3dzyA-1xlsA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DZY_A_9CRA463_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		12 / 12 ILE A 268
ALA A 271
GLN A 275
ASN A 306
SER A 312
PHE A 313
ARG A 316
LEU A 326
ALA A 327
VAL A 342
CYH A 432
LEU A 436
 9CR  A7223 (-3.9A)
9CR  A7223 (-3.5A)
9CR  A7223 (-4.6A)
9CR  A7223 (-3.9A)
9CR  A7223 ( 4.0A)
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
9CR  A7223 ( 4.5A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
 0.67A 3dzyA-3dzuA:
34.1		 3dzyA-3dzuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DZY_A_9CRA463_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		5 / 12 ILE A 268
ALA A 272
SER A 312
PHE A 313
VAL A 342
 9CR  A7223 (-3.9A)
9CR  A7223 (-4.2A)
9CR  A7223 ( 4.0A)
9CR  A7223 (-4.5A)
9CR  A7223 ( 4.5A)
 1.13A 3dzyA-3dzuA:
34.1		 3dzyA-3dzuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DZY_A_9CRA463_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5uan RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		12 / 12 ILE A 268
ALA A 271
GLN A 275
ASN A 306
SER A 312
PHE A 313
ARG A 316
LEU A 326
ALA A 327
VAL A 342
CYH A 432
LEU A 436
 9CR  A 503 (-4.0A)
9CR  A 503 (-3.5A)
9CR  A 503 (-3.8A)
None
None
9CR  A 503 (-4.7A)
9CR  A 503 (-3.0A)
9CR  A 503 (-4.3A)
9CR  A 503 (-3.4A)
None
9CR  A 503 (-3.3A)
9CR  A 503 ( 4.8A)
 0.84A 3dzyA-5uanA:
31.8		 3dzyA-5uanA:
78.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3E00_A_9CRA7223_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xiu RXR-LIKE PROTEIN
(Biomphalaria
glabrata) 		12 / 12 ILE A 242
ALA A 245
ALA A 246
GLN A 249
TRP A 279
ASN A 280
PHE A 287
ARG A 290
ALA A 301
VAL A 316
ILE A 319
CYH A 406
 9CR  A 201 ( 4.4A)
9CR  A 201 (-3.6A)
9CR  A 201 (-3.6A)
9CR  A 201 (-4.1A)
None
None
9CR  A 201 (-4.7A)
9CR  A 201 (-2.8A)
9CR  A 201 (-3.4A)
9CR  A 201 (-4.2A)
None
9CR  A 201 (-3.6A)
 0.47A 3e00A-1xiuA:
31.1		 3e00A-1xiuA:
62.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3E00_A_9CRA7223_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xls RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		12 / 12 ILE A 268
ALA A 271
ALA A 272
GLN A 275
TRP A 305
ASN A 306
PHE A 313
ARG A 316
ALA A 327
VAL A 342
ILE A 345
CYH A 432
 9CR  A 801 (-3.9A)
9CR  A 801 (-3.6A)
9CR  A 801 (-3.5A)
9CR  A 801 (-4.7A)
None
None
9CR  A 801 (-4.3A)
9CR  A 801 (-2.6A)
9CR  A 801 (-3.3A)
9CR  A 801 ( 4.3A)
9CR  A 801 ( 4.5A)
9CR  A 801 ( 3.7A)
 0.42A 3e00A-1xlsA:
33.3		 3e00A-1xlsA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3E00_A_9CRA7223_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xls RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		6 / 12 ILE A 268
ALA A 271
GLN A 275
PHE A 313
VAL A 342
ILE A 345
 9CR  A 801 (-3.9A)
9CR  A 801 (-3.6A)
9CR  A 801 (-4.7A)
9CR  A 801 (-4.3A)
9CR  A 801 ( 4.3A)
9CR  A 801 ( 4.5A)
 1.37A 3e00A-1xlsA:
33.3		 3e00A-1xlsA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3E00_A_9CRA7223_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		9 / 12 ALA A 271
ALA A 272
GLN A 275
TRP A 305
ASN A 306
PHE A 313
ARG A 316
VAL A 342
ILE A 345
 9CR  A7223 (-3.5A)
9CR  A7223 (-4.2A)
9CR  A7223 (-4.6A)
None
9CR  A7223 (-3.9A)
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 ( 4.5A)
9CR  A7223 ( 4.9A)
 0.74A 3e00A-3dzuA:
34.6		 3e00A-3dzuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3E00_A_9CRA7223_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		10 / 12 ILE A 268
ALA A 271
ALA A 272
GLN A 275
TRP A 305
PHE A 313
ARG A 316
ALA A 327
VAL A 342
CYH A 432
 9CR  A7223 (-3.9A)
9CR  A7223 (-3.5A)
9CR  A7223 (-4.2A)
9CR  A7223 (-4.6A)
None
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 ( 4.7A)
9CR  A7223 ( 4.5A)
9CR  A7223 (-3.8A)
 0.60A 3e00A-3dzuA:
34.6		 3e00A-3dzuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3E00_A_9CRA7223_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		10 / 12 ILE A 268
ALA A 271
ALA A 272
GLN A 275
TRP A 305
PHE A 313
ARG A 316
VAL A 342
ILE A 345
CYH A 432
 9CR  A7223 (-3.9A)
9CR  A7223 (-3.5A)
9CR  A7223 (-4.2A)
9CR  A7223 (-4.6A)
None
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 ( 4.5A)
9CR  A7223 ( 4.9A)
9CR  A7223 (-3.8A)
 0.51A 3e00A-3dzuA:
34.6		 3e00A-3dzuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3E00_A_9CRA7223_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5uan RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		7 / 12 ALA A 271
ALA A 272
GLN A 275
PHE A 313
ARG A 316
ALA A 327
ILE A 428
 9CR  A 503 (-3.5A)
9CR  A 503 (-3.5A)
9CR  A 503 (-3.8A)
9CR  A 503 (-4.7A)
9CR  A 503 (-3.0A)
9CR  A 503 (-3.4A)
None
 1.32A 3e00A-5uanA:
33.5		 3e00A-5uanA:
78.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3E00_A_9CRA7223_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5uan RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		12 / 12 ILE A 268
ALA A 271
ALA A 272
GLN A 275
TRP A 305
ASN A 306
PHE A 313
ARG A 316
ALA A 327
VAL A 342
ILE A 345
CYH A 432
 9CR  A 503 (-4.0A)
9CR  A 503 (-3.5A)
9CR  A 503 (-3.5A)
9CR  A 503 (-3.8A)
None
None
9CR  A 503 (-4.7A)
9CR  A 503 (-3.0A)
9CR  A 503 (-3.4A)
None
None
9CR  A 503 (-3.3A)
 0.56A 3e00A-5uanA:
33.5		 3e00A-5uanA:
78.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FAL_A_REAA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xiu RXR-LIKE PROTEIN
(Biomphalaria
glabrata) 		10 / 10 ILE A 242
ALA A 245
ALA A 246
GLN A 249
PHE A 287
ARG A 290
ALA A 301
VAL A 316
ILE A 319
CYH A 406
 9CR  A 201 ( 4.4A)
9CR  A 201 (-3.6A)
9CR  A 201 (-3.6A)
9CR  A 201 (-4.1A)
9CR  A 201 (-4.7A)
9CR  A 201 (-2.8A)
9CR  A 201 (-3.4A)
9CR  A 201 (-4.2A)
None
9CR  A 201 (-3.6A)
 0.41A 3falA-1xiuA:
30.1		 3falA-1xiuA:
81.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FAL_A_REAA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xls RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		10 / 10 ILE A 268
ALA A 271
ALA A 272
GLN A 275
PHE A 313
ARG A 316
ALA A 327
VAL A 342
ILE A 345
CYH A 432
 9CR  A 801 (-3.9A)
9CR  A 801 (-3.6A)
9CR  A 801 (-3.5A)
9CR  A 801 (-4.7A)
9CR  A 801 (-4.3A)
9CR  A 801 (-2.6A)
9CR  A 801 (-3.3A)
9CR  A 801 ( 4.3A)
9CR  A 801 ( 4.5A)
9CR  A 801 ( 3.7A)
 0.37A 3falA-1xlsA:
29.3		 3falA-1xlsA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FAL_A_REAA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		10 / 10 ILE A 268
ALA A 271
ALA A 272
GLN A 275
PHE A 313
ARG A 316
ALA A 327
VAL A 342
ILE A 345
CYH A 432
 9CR  A7223 (-3.9A)
9CR  A7223 (-3.5A)
9CR  A7223 (-4.2A)
9CR  A7223 (-4.6A)
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 ( 4.7A)
9CR  A7223 ( 4.5A)
9CR  A7223 ( 4.9A)
9CR  A7223 (-3.8A)
 0.78A 3falA-3dzuA:
29.5		 3falA-3dzuA:
51.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FAL_A_REAA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5uan RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		7 / 10 ALA A 271
ALA A 272
GLN A 275
PHE A 313
ARG A 316
ALA A 327
ILE A 428
 9CR  A 503 (-3.5A)
9CR  A 503 (-3.5A)
9CR  A 503 (-3.8A)
9CR  A 503 (-4.7A)
9CR  A 503 (-3.0A)
9CR  A 503 (-3.4A)
None
 1.40A 3falA-5uanA:
28.7		 3falA-5uanA:
66.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FAL_A_REAA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5uan RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		10 / 10 ILE A 268
ALA A 271
ALA A 272
GLN A 275
PHE A 313
ARG A 316
ALA A 327
VAL A 342
ILE A 345
CYH A 432
 9CR  A 503 (-4.0A)
9CR  A 503 (-3.5A)
9CR  A 503 (-3.5A)
9CR  A 503 (-3.8A)
9CR  A 503 (-4.7A)
9CR  A 503 (-3.0A)
9CR  A 503 (-3.4A)
None
None
9CR  A 503 (-3.3A)
 0.64A 3falA-5uanA:
28.7		 3falA-5uanA:
66.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FAL_C_REAC501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xiu RXR-LIKE PROTEIN
(Biomphalaria
glabrata) 		10 / 10 ILE A 242
ALA A 245
ALA A 246
GLN A 249
PHE A 287
ARG A 290
LEU A 300
ALA A 301
ILE A 319
CYH A 406
 9CR  A 201 ( 4.4A)
9CR  A 201 (-3.6A)
9CR  A 201 (-3.6A)
9CR  A 201 (-4.1A)
9CR  A 201 (-4.7A)
9CR  A 201 (-2.8A)
9CR  A 201 (-4.4A)
9CR  A 201 (-3.4A)
None
9CR  A 201 (-3.6A)
 0.36A 3falC-1xiuA:
30.1		 3falC-1xiuA:
81.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FAL_C_REAC501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xls RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		10 / 10 ILE A 268
ALA A 271
ALA A 272
GLN A 275
PHE A 313
ARG A 316
LEU A 326
ALA A 327
ILE A 345
CYH A 432
 9CR  A 801 (-3.9A)
9CR  A 801 (-3.6A)
9CR  A 801 (-3.5A)
9CR  A 801 (-4.7A)
9CR  A 801 (-4.3A)
9CR  A 801 (-2.6A)
9CR  A 801 (-4.1A)
9CR  A 801 (-3.3A)
9CR  A 801 ( 4.5A)
9CR  A 801 ( 3.7A)
 0.32A 3falC-1xlsA:
29.4		 3falC-1xlsA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FAL_C_REAC501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		10 / 10 ILE A 268
ALA A 271
ALA A 272
GLN A 275
PHE A 313
ARG A 316
LEU A 326
ALA A 327
ILE A 345
CYH A 432
 9CR  A7223 (-3.9A)
9CR  A7223 (-3.5A)
9CR  A7223 (-4.2A)
9CR  A7223 (-4.6A)
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
9CR  A7223 ( 4.9A)
9CR  A7223 (-3.8A)
 0.79A 3falC-3dzuA:
29.8		 3falC-3dzuA:
51.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FAL_C_REAC501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5uan RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		8 / 10 ALA A 271
ALA A 272
GLN A 275
PHE A 313
ARG A 316
LEU A 326
ALA A 327
ILE A 428
 9CR  A 503 (-3.5A)
9CR  A 503 (-3.5A)
9CR  A 503 (-3.8A)
9CR  A 503 (-4.7A)
9CR  A 503 (-3.0A)
9CR  A 503 (-4.3A)
9CR  A 503 (-3.4A)
None
 1.37A 3falC-5uanA:
29.1		 3falC-5uanA:
66.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FAL_C_REAC501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5uan RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		10 / 10 ILE A 268
ALA A 271
ALA A 272
GLN A 275
PHE A 313
ARG A 316
LEU A 326
ALA A 327
ILE A 345
CYH A 432
 9CR  A 503 (-4.0A)
9CR  A 503 (-3.5A)
9CR  A 503 (-3.5A)
9CR  A 503 (-3.8A)
9CR  A 503 (-4.7A)
9CR  A 503 (-3.0A)
9CR  A 503 (-4.3A)
9CR  A 503 (-3.4A)
None
9CR  A 503 (-3.3A)
 0.59A 3falC-5uanA:
29.1		 3falC-5uanA:
66.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FC6_A_REAA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xiu RXR-LIKE PROTEIN
(Biomphalaria
glabrata) 		11 / 11 ILE A 242
ALA A 245
ALA A 246
GLN A 249
TRP A 279
PHE A 287
ARG A 290
LEU A 300
ALA A 301
ILE A 319
CYH A 406
 9CR  A 201 ( 4.4A)
9CR  A 201 (-3.6A)
9CR  A 201 (-3.6A)
9CR  A 201 (-4.1A)
None
9CR  A 201 (-4.7A)
9CR  A 201 (-2.8A)
9CR  A 201 (-4.4A)
9CR  A 201 (-3.4A)
None
9CR  A 201 (-3.6A)
 0.40A 3fc6A-1xiuA:
30.7		 3fc6A-1xiuA:
81.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FC6_A_REAA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xls RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		11 / 11 ILE A 268
ALA A 271
ALA A 272
GLN A 275
TRP A 305
PHE A 313
ARG A 316
LEU A 326
ALA A 327
ILE A 345
CYH A 432
 9CR  A 801 (-3.9A)
9CR  A 801 (-3.6A)
9CR  A 801 (-3.5A)
9CR  A 801 (-4.7A)
None
9CR  A 801 (-4.3A)
9CR  A 801 (-2.6A)
9CR  A 801 (-4.1A)
9CR  A 801 (-3.3A)
9CR  A 801 ( 4.5A)
9CR  A 801 ( 3.7A)
 0.42A 3fc6A-1xlsA:
30.0		 3fc6A-1xlsA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FC6_A_REAA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		11 / 11 ILE A 268
ALA A 271
ALA A 272
GLN A 275
TRP A 305
PHE A 313
ARG A 316
LEU A 326
ALA A 327
ILE A 345
CYH A 432
 9CR  A7223 (-3.9A)
9CR  A7223 (-3.5A)
9CR  A7223 (-4.2A)
9CR  A7223 (-4.6A)
None
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
9CR  A7223 ( 4.9A)
9CR  A7223 (-3.8A)
 0.72A 3fc6A-3dzuA:
30.5		 3fc6A-3dzuA:
51.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FC6_A_REAA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		7 / 11 ILE A 268
ALA A 271
GLN A 275
PHE A 313
ARG A 316
ALA A 327
ILE A 345
 9CR  A7223 (-3.9A)
9CR  A7223 (-3.5A)
9CR  A7223 (-4.6A)
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 ( 4.7A)
9CR  A7223 ( 4.9A)
 1.50A 3fc6A-3dzuA:
30.5		 3fc6A-3dzuA:
51.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FC6_A_REAA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5uan RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		7 / 11 ALA A 271
ALA A 272
PHE A 313
ARG A 316
LEU A 326
ALA A 327
ILE A 428
 9CR  A 503 (-3.5A)
9CR  A 503 (-3.5A)
9CR  A 503 (-4.7A)
9CR  A 503 (-3.0A)
9CR  A 503 (-4.3A)
9CR  A 503 (-3.4A)
None
 1.26A 3fc6A-5uanA:
29.9		 3fc6A-5uanA:
66.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FC6_A_REAA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5uan RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		11 / 11 ILE A 268
ALA A 271
ALA A 272
GLN A 275
TRP A 305
PHE A 313
ARG A 316
LEU A 326
ALA A 327
ILE A 345
CYH A 432
 9CR  A 503 (-4.0A)
9CR  A 503 (-3.5A)
9CR  A 503 (-3.5A)
9CR  A 503 (-3.8A)
None
9CR  A 503 (-4.7A)
9CR  A 503 (-3.0A)
9CR  A 503 (-4.3A)
9CR  A 503 (-3.4A)
None
9CR  A 503 (-3.3A)
 0.58A 3fc6A-5uanA:
29.9		 3fc6A-5uanA:
66.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FC6_C_REAC501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xiu RXR-LIKE PROTEIN
(Biomphalaria
glabrata) 		12 / 12 VAL A 239
CYH A 243
ALA A 245
ALA A 246
GLN A 249
LEU A 283
PHE A 287
ARG A 290
LEU A 300
ALA A 301
VAL A 316
CYH A 406
 9CR  A 201 ( 4.8A)
9CR  A 201 ( 3.8A)
9CR  A 201 (-3.6A)
9CR  A 201 (-3.6A)
9CR  A 201 (-4.1A)
9CR  A 201 ( 4.1A)
9CR  A 201 (-4.7A)
9CR  A 201 (-2.8A)
9CR  A 201 (-4.4A)
9CR  A 201 (-3.4A)
9CR  A 201 (-4.2A)
9CR  A 201 (-3.6A)
 0.35A 3fc6C-1xiuA:
31.3		 3fc6C-1xiuA:
81.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FC6_C_REAC501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xls RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		6 / 12 VAL A 265
ALA A 271
GLN A 275
PHE A 313
ARG A 316
VAL A 342
 9CR  A 801 ( 4.6A)
9CR  A 801 (-3.6A)
9CR  A 801 (-4.7A)
9CR  A 801 (-4.3A)
9CR  A 801 (-2.6A)
9CR  A 801 ( 4.3A)
 1.50A 3fc6C-1xlsA:
30.5		 3fc6C-1xlsA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FC6_C_REAC501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xls RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		12 / 12 VAL A 265
CYH A 269
ALA A 271
ALA A 272
GLN A 275
LEU A 309
PHE A 313
ARG A 316
LEU A 326
ALA A 327
VAL A 342
CYH A 432
 9CR  A 801 ( 4.6A)
9CR  A 801 ( 4.5A)
9CR  A 801 (-3.6A)
9CR  A 801 (-3.5A)
9CR  A 801 (-4.7A)
9CR  A 801 (-4.2A)
9CR  A 801 (-4.3A)
9CR  A 801 (-2.6A)
9CR  A 801 (-4.1A)
9CR  A 801 (-3.3A)
9CR  A 801 ( 4.3A)
9CR  A 801 ( 3.7A)
 0.38A 3fc6C-1xlsA:
30.5		 3fc6C-1xlsA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FC6_C_REAC501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		12 / 12 VAL A 265
CYH A 269
ALA A 271
ALA A 272
GLN A 275
LEU A 309
PHE A 313
ARG A 316
LEU A 326
ALA A 327
VAL A 342
CYH A 432
 9CR  A7223 ( 4.5A)
None
9CR  A7223 (-3.5A)
9CR  A7223 (-4.2A)
9CR  A7223 (-4.6A)
9CR  A7223 ( 4.4A)
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
9CR  A7223 ( 4.5A)
9CR  A7223 (-3.8A)
 0.71A 3fc6C-3dzuA:
30.3		 3fc6C-3dzuA:
51.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FC6_C_REAC501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5uan RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		12 / 12 VAL A 265
CYH A 269
ALA A 271
ALA A 272
GLN A 275
LEU A 309
PHE A 313
ARG A 316
LEU A 326
ALA A 327
VAL A 342
CYH A 432
 None
9CR  A 503 ( 4.4A)
9CR  A 503 (-3.5A)
9CR  A 503 (-3.5A)
9CR  A 503 (-3.8A)
9CR  A 503 (-3.7A)
9CR  A 503 (-4.7A)
9CR  A 503 (-3.0A)
9CR  A 503 (-4.3A)
9CR  A 503 (-3.4A)
None
9CR  A 503 (-3.3A)
 0.58A 3fc6C-5uanA:
30.0		 3fc6C-5uanA:
66.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xiu RXR-LIKE PROTEIN
(Biomphalaria
glabrata) 		6 / 12 ALA A 245
ALA A 246
GLN A 249
TRP A 279
ARG A 290
ILE A 402
 9CR  A 201 (-3.6A)
9CR  A 201 (-3.6A)
9CR  A 201 (-4.1A)
None
9CR  A 201 (-2.8A)
None
 1.28A 3h0aA-1xiuA:
29.4		 3h0aA-1xiuA:
82.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xiu RXR-LIKE PROTEIN
(Biomphalaria
glabrata) 		10 / 12 ALA A 245
ALA A 246
GLN A 249
TRP A 279
LEU A 283
ARG A 290
LEU A 300
VAL A 316
ILE A 319
LEU A 410
 9CR  A 201 (-3.6A)
9CR  A 201 (-3.6A)
9CR  A 201 (-4.1A)
None
9CR  A 201 ( 4.1A)
9CR  A 201 (-2.8A)
9CR  A 201 (-4.4A)
9CR  A 201 (-4.2A)
None
9CR  A 201 ( 4.8A)
 0.69A 3h0aA-1xiuA:
29.4		 3h0aA-1xiuA:
82.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xiu RXR-LIKE PROTEIN
(Biomphalaria
glabrata) 		8 / 12 ALA A 245
ALA A 246
LEU A 283
ARG A 290
LEU A 300
VAL A 316
ILE A 319
CYH A 406
 9CR  A 201 (-3.6A)
9CR  A 201 (-3.6A)
9CR  A 201 ( 4.1A)
9CR  A 201 (-2.8A)
9CR  A 201 (-4.4A)
9CR  A 201 (-4.2A)
None
9CR  A 201 (-3.6A)
 0.75A 3h0aA-1xiuA:
29.4		 3h0aA-1xiuA:
82.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xiu RXR-LIKE PROTEIN
(Biomphalaria
glabrata) 		9 / 12 ALA A 245
GLN A 249
LEU A 283
ARG A 290
LEU A 300
ALA A 301
VAL A 316
ILE A 319
LEU A 410
 9CR  A 201 (-3.6A)
9CR  A 201 (-4.1A)
9CR  A 201 ( 4.1A)
9CR  A 201 (-2.8A)
9CR  A 201 (-4.4A)
9CR  A 201 (-3.4A)
9CR  A 201 (-4.2A)
None
9CR  A 201 ( 4.8A)
 0.71A 3h0aA-1xiuA:
29.4		 3h0aA-1xiuA:
82.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xls RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		7 / 12 ALA A 271
ALA A 272
GLN A 275
ARG A 316
LEU A 326
ALA A 327
ILE A 428
 9CR  A 801 (-3.6A)
9CR  A 801 (-3.5A)
9CR  A 801 (-4.7A)
9CR  A 801 (-2.6A)
9CR  A 801 (-4.1A)
9CR  A 801 (-3.3A)
None
 1.30A 3h0aA-1xlsA:
31.5		 3h0aA-1xlsA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xls RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		11 / 12 ALA A 271
ALA A 272
GLN A 275
TRP A 305
LEU A 309
ARG A 316
LEU A 326
ALA A 327
VAL A 342
ILE A 345
LEU A 436
 9CR  A 801 (-3.6A)
9CR  A 801 (-3.5A)
9CR  A 801 (-4.7A)
None
9CR  A 801 (-4.2A)
9CR  A 801 (-2.6A)
9CR  A 801 (-4.1A)
9CR  A 801 (-3.3A)
9CR  A 801 ( 4.3A)
9CR  A 801 ( 4.5A)
9CR  A 801 (-4.7A)
 0.71A 3h0aA-1xlsA:
31.5		 3h0aA-1xlsA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xls RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		9 / 12 ALA A 271
ALA A 272
LEU A 309
ARG A 316
LEU A 326
ALA A 327
VAL A 342
ILE A 345
CYH A 432
 9CR  A 801 (-3.6A)
9CR  A 801 (-3.5A)
9CR  A 801 (-4.2A)
9CR  A 801 (-2.6A)
9CR  A 801 (-4.1A)
9CR  A 801 (-3.3A)
9CR  A 801 ( 4.3A)
9CR  A 801 ( 4.5A)
9CR  A 801 ( 3.7A)
 0.81A 3h0aA-1xlsA:
31.5		 3h0aA-1xlsA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xls RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		6 / 12 ALA A 271
GLN A 275
ARG A 316
ALA A 327
VAL A 342
ILE A 345
 9CR  A 801 (-3.6A)
9CR  A 801 (-4.7A)
9CR  A 801 (-2.6A)
9CR  A 801 (-3.3A)
9CR  A 801 ( 4.3A)
9CR  A 801 ( 4.5A)
 1.44A 3h0aA-1xlsA:
31.5		 3h0aA-1xlsA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		8 / 12 ALA A 271
ALA A 272
GLN A 275
TRP A 305
LEU A 309
ARG A 316
LEU A 326
LEU A 436
 9CR  A7223 (-3.5A)
9CR  A7223 (-4.2A)
9CR  A7223 (-4.6A)
None
9CR  A7223 ( 4.4A)
9CR  A7223 (-3.7A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
 0.78A 3h0aA-3dzuA:
31.5		 3h0aA-3dzuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		9 / 12 ALA A 271
ALA A 272
TRP A 305
LEU A 309
ARG A 316
LEU A 326
VAL A 342
ILE A 345
LEU A 436
 9CR  A7223 (-3.5A)
9CR  A7223 (-4.2A)
None
9CR  A7223 ( 4.4A)
9CR  A7223 (-3.7A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.5A)
9CR  A7223 ( 4.9A)
9CR  A7223 ( 4.7A)
 0.74A 3h0aA-3dzuA:
31.5		 3h0aA-3dzuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		6 / 12 ALA A 271
GLN A 275
TRP A 305
ARG A 316
LEU A 326
ILE A 428
 9CR  A7223 (-3.5A)
9CR  A7223 (-4.6A)
None
9CR  A7223 (-3.7A)
9CR  A7223 (-3.8A)
None
 1.35A 3h0aA-3dzuA:
31.5		 3h0aA-3dzuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		7 / 12 ALA A 271
LEU A 309
ARG A 316
LEU A 326
VAL A 342
ILE A 345
CYH A 432
 9CR  A7223 (-3.5A)
9CR  A7223 ( 4.4A)
9CR  A7223 (-3.7A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.5A)
9CR  A7223 ( 4.9A)
9CR  A7223 (-3.8A)
 0.93A 3h0aA-3dzuA:
31.5		 3h0aA-3dzuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5uan RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		12 / 12 ALA A 271
ALA A 272
GLN A 275
TRP A 305
LEU A 309
ARG A 316
LEU A 326
ALA A 327
VAL A 342
ILE A 345
CYH A 432
LEU A 436
 9CR  A 503 (-3.5A)
9CR  A 503 (-3.5A)
9CR  A 503 (-3.8A)
None
9CR  A 503 (-3.7A)
9CR  A 503 (-3.0A)
9CR  A 503 (-4.3A)
9CR  A 503 (-3.4A)
None
None
9CR  A 503 (-3.3A)
9CR  A 503 ( 4.8A)
 0.70A 3h0aA-5uanA:
31.7		 3h0aA-5uanA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H0A_A_9RAA500_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xiu RXR-LIKE PROTEIN
(Biomphalaria
glabrata) 		3 / 3 ILE A 242
PHE A 287
HIS A 409
 9CR  A 201 ( 4.4A)
9CR  A 201 (-4.7A)
9CR  A 201 (-4.8A)
 0.55A 3h0aA-1xiuA:
29.4		 3h0aA-1xiuA:
82.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H0A_A_9RAA500_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xls RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		3 / 3 ILE A 268
PHE A 313
HIS A 435
 9CR  A 801 (-3.9A)
9CR  A 801 (-4.3A)
None
 0.54A 3h0aA-1xlsA:
31.5		 3h0aA-1xlsA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H0A_A_9RAA500_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		3 / 3 ILE A 268
PHE A 313
HIS A 435
 9CR  A7223 (-3.9A)
9CR  A7223 (-4.5A)
9CR  A7223 (-4.3A)
 0.66A 3h0aA-3dzuA:
31.5		 3h0aA-3dzuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LBD_A_9CRA424_1
(RETINOIC ACID
RECEPTOR GAMMA)		 1xdk RETINOIC ACID
RECEPTOR, BETA
(Mus
musculus) 		10 / 12 PHE B 221
ALA B 225
LEU B 259
LEU B 262
ILE B 266
ARG B 269
SER B 280
PHE B 295
GLY B 384
ILE B 403
 9CR  B 600 ( 4.7A)
9CR  B 600 (-3.8A)
None
9CR  B 600 (-3.9A)
9CR  B 600 ( 3.8A)
9CR  B 600 (-3.8A)
9CR  B 600 (-3.0A)
9CR  B 600 (-3.9A)
9CR  B 600 ( 4.6A)
9CR  B 600 ( 4.4A)
 0.55A 3lbdA-1xdkB:
37.5		 3lbdA-1xdkB:
79.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OAP_A_9CRA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xiu RXR-LIKE PROTEIN
(Biomphalaria
glabrata) 		12 / 12 ILE A 242
ALA A 245
ALA A 246
GLN A 249
PHE A 287
ARG A 290
LEU A 300
ALA A 301
VAL A 316
ILE A 319
CYH A 406
LEU A 410
 9CR  A 201 ( 4.4A)
9CR  A 201 (-3.6A)
9CR  A 201 (-3.6A)
9CR  A 201 (-4.1A)
9CR  A 201 (-4.7A)
9CR  A 201 (-2.8A)
9CR  A 201 (-4.4A)
9CR  A 201 (-3.4A)
9CR  A 201 (-4.2A)
None
9CR  A 201 (-3.6A)
9CR  A 201 ( 4.8A)
 0.27A 3oapA-1xiuA:
33.1		 3oapA-1xiuA:
81.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OAP_A_9CRA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xiu RXR-LIKE PROTEIN
(Biomphalaria
glabrata) 		6 / 12 ILE A 242
ALA A 246
GLN A 249
PHE A 287
VAL A 316
ILE A 319
 9CR  A 201 ( 4.4A)
9CR  A 201 (-3.6A)
9CR  A 201 (-4.1A)
9CR  A 201 (-4.7A)
9CR  A 201 (-4.2A)
None
 1.43A 3oapA-1xiuA:
33.1		 3oapA-1xiuA:
81.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OAP_A_9CRA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xls RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		12 / 12 ILE A 268
ALA A 271
ALA A 272
GLN A 275
PHE A 313
ARG A 316
LEU A 326
ALA A 327
VAL A 342
ILE A 345
CYH A 432
LEU A 436
 9CR  A 801 (-3.9A)
9CR  A 801 (-3.6A)
9CR  A 801 (-3.5A)
9CR  A 801 (-4.7A)
9CR  A 801 (-4.3A)
9CR  A 801 (-2.6A)
9CR  A 801 (-4.1A)
9CR  A 801 (-3.3A)
9CR  A 801 ( 4.3A)
9CR  A 801 ( 4.5A)
9CR  A 801 ( 3.7A)
9CR  A 801 (-4.7A)
 0.34A 3oapA-1xlsA:
35.6		 3oapA-1xlsA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OAP_A_9CRA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		12 / 12 ILE A 268
ALA A 271
ALA A 272
GLN A 275
PHE A 313
ARG A 316
LEU A 326
ALA A 327
VAL A 342
ILE A 345
CYH A 432
LEU A 436
 9CR  A7223 (-3.9A)
9CR  A7223 (-3.5A)
9CR  A7223 (-4.2A)
9CR  A7223 (-4.6A)
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
9CR  A7223 ( 4.5A)
9CR  A7223 ( 4.9A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
 0.62A 3oapA-3dzuA:
33.9		 3oapA-3dzuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OLS_B_ESTB600_1
(ESTROGEN RECEPTOR
BETA)		 1xls RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		5 / 12 ALA A 272
LEU A 309
ARG A 316
ILE A 345
LEU A 436
 9CR  A 801 (-3.5A)
9CR  A 801 (-4.2A)
9CR  A 801 (-2.6A)
9CR  A 801 ( 4.5A)
9CR  A 801 (-4.7A)
 1.04A 3olsB-1xlsA:
25.2		 3olsB-1xlsA:
30.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q95_A_ESLA700_1
(ESTROGEN RECEPTOR)		 1xiu RXR-LIKE PROTEIN
(Biomphalaria
glabrata) 		5 / 12 ALA A 246
LEU A 283
ARG A 290
ILE A 402
GLY A 403
 9CR  A 201 (-3.6A)
9CR  A 201 ( 4.1A)
9CR  A 201 (-2.8A)
None
None
 0.94A 3q95A-1xiuA:
23.0		 3q95A-1xiuA:
28.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3Q95_A_ESLA700_1
(ESTROGEN RECEPTOR)		 1xls RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		5 / 12 ALA A 272
LEU A 309
ARG A 316
ILE A 428
GLY A 429
 9CR  A 801 (-3.5A)
9CR  A 801 (-4.2A)
9CR  A 801 (-2.6A)
None
None
 1.00A 3q95A-1xlsA:
26.0		 3q95A-1xlsA:
30.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q95_A_ESLA700_1
(ESTROGEN RECEPTOR)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		5 / 12 ALA A 272
LEU A 309
ARG A 316
ILE A 428
GLY A 429
 9CR  A7223 (-4.2A)
9CR  A7223 ( 4.4A)
9CR  A7223 (-3.7A)
None
None
 0.99A 3q95A-3dzuA:
25.5		 3q95A-3dzuA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q95_A_ESLA700_1
(ESTROGEN RECEPTOR)		 5uan RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		5 / 12 ALA A 272
LEU A 309
ARG A 316
ILE A 428
GLY A 429
 9CR  A 503 (-3.5A)
9CR  A 503 (-3.7A)
9CR  A 503 (-3.0A)
None
None
 1.07A 3q95A-5uanA:
25.5		 3q95A-5uanA:
24.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q95_B_ESLB700_1
(ESTROGEN RECEPTOR)		 1xiu RXR-LIKE PROTEIN
(Biomphalaria
glabrata) 		5 / 12 ALA A 246
LEU A 283
ARG A 290
ILE A 402
GLY A 403
 9CR  A 201 (-3.6A)
9CR  A 201 ( 4.1A)
9CR  A 201 (-2.8A)
None
None
 0.97A 3q95B-1xiuA:
22.7		 3q95B-1xiuA:
28.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3Q95_B_ESLB700_1
(ESTROGEN RECEPTOR)		 1xls RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		5 / 12 ALA A 272
LEU A 309
ARG A 316
ILE A 428
GLY A 429
 9CR  A 801 (-3.5A)
9CR  A 801 (-4.2A)
9CR  A 801 (-2.6A)
None
None
 1.04A 3q95B-1xlsA:
25.4		 3q95B-1xlsA:
30.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q95_B_ESLB700_1
(ESTROGEN RECEPTOR)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		5 / 12 ALA A 272
LEU A 309
ARG A 316
ILE A 428
GLY A 429
 9CR  A7223 (-4.2A)
9CR  A7223 ( 4.4A)
9CR  A7223 (-3.7A)
None
None
 1.01A 3q95B-3dzuA:
25.0		 3q95B-3dzuA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q95_B_ESLB700_1
(ESTROGEN RECEPTOR)		 5uan RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		5 / 12 ALA A 272
LEU A 309
ARG A 316
ILE A 428
GLY A 429
 9CR  A 503 (-3.5A)
9CR  A 503 (-3.7A)
9CR  A 503 (-3.0A)
None
None
 1.09A 3q95B-5uanA:
24.9		 3q95B-5uanA:
24.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UVV_B_9CRB501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xiu RXR-LIKE PROTEIN
(Biomphalaria
glabrata) 		12 / 12 ILE A 242
ALA A 245
ALA A 246
GLN A 249
LEU A 283
PHE A 287
ARG A 290
ALA A 301
VAL A 316
ILE A 319
CYH A 406
LEU A 410
 9CR  A 201 ( 4.4A)
9CR  A 201 (-3.6A)
9CR  A 201 (-3.6A)
9CR  A 201 (-4.1A)
9CR  A 201 ( 4.1A)
9CR  A 201 (-4.7A)
9CR  A 201 (-2.8A)
9CR  A 201 (-3.4A)
9CR  A 201 (-4.2A)
None
9CR  A 201 (-3.6A)
9CR  A 201 ( 4.8A)
 0.36A 3uvvB-1xiuA:
32.4		 3uvvB-1xiuA:
81.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UVV_B_9CRB501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xls RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		11 / 12 ILE A 268
ALA A 271
ALA A 272
GLN A 275
LEU A 309
PHE A 313
ARG A 316
ALA A 327
VAL A 342
CYH A 432
LEU A 436
 9CR  A 801 (-3.9A)
9CR  A 801 (-3.6A)
9CR  A 801 (-3.5A)
9CR  A 801 (-4.7A)
9CR  A 801 (-4.2A)
9CR  A 801 (-4.3A)
9CR  A 801 (-2.6A)
9CR  A 801 (-3.3A)
9CR  A 801 ( 4.3A)
9CR  A 801 ( 3.7A)
9CR  A 801 (-4.7A)
 0.43A 3uvvB-1xlsA:
36.0		 3uvvB-1xlsA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UVV_B_9CRB501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xls RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		11 / 12 ILE A 268
ALA A 271
ALA A 272
GLN A 275
LEU A 309
PHE A 313
ARG A 316
ALA A 327
VAL A 342
ILE A 345
CYH A 432
 9CR  A 801 (-3.9A)
9CR  A 801 (-3.6A)
9CR  A 801 (-3.5A)
9CR  A 801 (-4.7A)
9CR  A 801 (-4.2A)
9CR  A 801 (-4.3A)
9CR  A 801 (-2.6A)
9CR  A 801 (-3.3A)
9CR  A 801 ( 4.3A)
9CR  A 801 ( 4.5A)
9CR  A 801 ( 3.7A)
 0.47A 3uvvB-1xlsA:
36.0		 3uvvB-1xlsA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UVV_B_9CRB501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xls RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		6 / 12 ILE A 268
ALA A 271
GLN A 275
PHE A 313
VAL A 342
ILE A 345
 9CR  A 801 (-3.9A)
9CR  A 801 (-3.6A)
9CR  A 801 (-4.7A)
9CR  A 801 (-4.3A)
9CR  A 801 ( 4.3A)
9CR  A 801 ( 4.5A)
 1.47A 3uvvB-1xlsA:
36.0		 3uvvB-1xlsA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UVV_B_9CRB501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		11 / 12 ILE A 268
ALA A 271
ALA A 272
GLN A 275
LEU A 309
PHE A 313
ARG A 316
VAL A 342
ILE A 345
CYH A 432
LEU A 436
 9CR  A7223 (-3.9A)
9CR  A7223 (-3.5A)
9CR  A7223 (-4.2A)
9CR  A7223 (-4.6A)
9CR  A7223 ( 4.4A)
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 ( 4.5A)
9CR  A7223 ( 4.9A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
 0.55A 3uvvB-3dzuA:
34.1		 3uvvB-3dzuA:
51.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UVV_B_9CRB501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		10 / 12 ILE A 268
ALA A 272
GLN A 275
LEU A 309
PHE A 313
ARG A 316
ALA A 327
VAL A 342
ILE A 345
CYH A 432
 9CR  A7223 (-3.9A)
9CR  A7223 (-4.2A)
9CR  A7223 (-4.6A)
9CR  A7223 ( 4.4A)
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 ( 4.7A)
9CR  A7223 ( 4.5A)
9CR  A7223 ( 4.9A)
9CR  A7223 (-3.8A)
 0.62A 3uvvB-3dzuA:
34.1		 3uvvB-3dzuA:
51.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UVV_B_9CRB501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		5 / 12 ILE A 268
ALA A 272
PHE A 313
VAL A 342
ILE A 345
 9CR  A7223 (-3.9A)
9CR  A7223 (-4.2A)
9CR  A7223 (-4.5A)
9CR  A7223 ( 4.5A)
9CR  A7223 ( 4.9A)
 1.25A 3uvvB-3dzuA:
34.1		 3uvvB-3dzuA:
51.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UVV_B_9CRB501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5uan RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		5 / 12 ALA A 271
ALA A 272
PHE A 313
ALA A 327
ILE A 428
 9CR  A 503 (-3.5A)
9CR  A 503 (-3.5A)
9CR  A 503 (-4.7A)
9CR  A 503 (-3.4A)
None
 1.23A 3uvvB-5uanA:
34.4		 3uvvB-5uanA:
66.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UVV_B_9CRB501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5uan RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		11 / 12 ILE A 268
ALA A 271
ALA A 272
GLN A 275
LEU A 309
PHE A 313
ARG A 316
ALA A 327
VAL A 342
ILE A 345
LEU A 436
 9CR  A 503 (-4.0A)
9CR  A 503 (-3.5A)
9CR  A 503 (-3.5A)
9CR  A 503 (-3.8A)
9CR  A 503 (-3.7A)
9CR  A 503 (-4.7A)
9CR  A 503 (-3.0A)
9CR  A 503 (-3.4A)
None
None
9CR  A 503 ( 4.8A)
 0.55A 3uvvB-5uanA:
34.4		 3uvvB-5uanA:
66.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UVV_B_9CRB501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5uan RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		10 / 12 ILE A 268
ALA A 271
GLN A 275
LEU A 309
PHE A 313
ARG A 316
ALA A 327
VAL A 342
ILE A 345
CYH A 432
 9CR  A 503 (-4.0A)
9CR  A 503 (-3.5A)
9CR  A 503 (-3.8A)
9CR  A 503 (-3.7A)
9CR  A 503 (-4.7A)
9CR  A 503 (-3.0A)
9CR  A 503 (-3.4A)
None
None
9CR  A 503 (-3.3A)
 0.70A 3uvvB-5uanA:
34.4		 3uvvB-5uanA:
66.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1476_0
(MJ0495-LIKE PROTEIN)		 1xiu RXR-LIKE PROTEIN
(Biomphalaria
glabrata) 		4 / 5 ILE A 242
ALA A 245
HIS A 305
ARG A 290
 9CR  A 201 ( 4.4A)
9CR  A 201 (-3.6A)
None
9CR  A 201 (-2.8A)
 1.17A 4ac9B-1xiuA:
undetectable
4ac9C-1xiuA:
undetectable		 4ac9B-1xiuA:
21.84
4ac9C-1xiuA:
21.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DM8_A_REAA501_1
(RETINOIC ACID
RECEPTOR BETA)		 1xdk RETINOIC ACID
RECEPTOR, BETA
(Mus
musculus) 		11 / 11 PHE B 221
CYH B 228
LEU B 259
LEU B 262
ILE B 263
ARG B 269
PHE B 279
SER B 280
LEU B 298
LEU B 391
ILE B 403
 9CR  B 600 ( 4.7A)
9CR  B 600 (-3.4A)
None
9CR  B 600 (-3.9A)
9CR  B 600 (-4.0A)
9CR  B 600 (-3.8A)
9CR  B 600 (-4.5A)
9CR  B 600 (-3.0A)
9CR  B 600 (-4.7A)
None
9CR  B 600 ( 4.4A)
 0.50A 4dm8A-1xdkB:
37.7		 4dm8A-1xdkB:
92.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DM8_B_REAB1501_1
(RETINOIC ACID
RECEPTOR BETA)		 1xdk RETINOIC ACID
RECEPTOR, BETA
(Mus
musculus) 		12 / 12 PHE B 192
PHE B 221
LEU B 224
ALA B 225
LEU B 259
LEU B 262
ILE B 263
ARG B 269
SER B 280
PHE B 295
GLY B 384
LEU B 391
 9CR  B 600 (-4.8A)
9CR  B 600 ( 4.7A)
9CR  B 600 ( 4.0A)
9CR  B 600 (-3.8A)
None
9CR  B 600 (-3.9A)
9CR  B 600 (-4.0A)
9CR  B 600 (-3.8A)
9CR  B 600 (-3.0A)
9CR  B 600 (-3.9A)
9CR  B 600 ( 4.6A)
None
 0.51A 4dm8B-1xdkB:
38.2		 4dm8B-1xdkB:
92.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xiu RXR-LIKE PROTEIN
(Biomphalaria
glabrata) 		11 / 12 ILE A 242
ALA A 245
ALA A 246
GLN A 249
LEU A 283
ILE A 284
PHE A 287
ARG A 290
LEU A 300
ALA A 301
VAL A 323
 9CR  A 201 ( 4.4A)
9CR  A 201 (-3.6A)
9CR  A 201 (-3.6A)
9CR  A 201 (-4.1A)
9CR  A 201 ( 4.1A)
None
9CR  A 201 (-4.7A)
9CR  A 201 (-2.8A)
9CR  A 201 (-4.4A)
9CR  A 201 (-3.4A)
None
 0.33A 4k6iA-1xiuA:
32.7		 4k6iA-1xiuA:
81.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xiu RXR-LIKE PROTEIN
(Biomphalaria
glabrata) 		8 / 12 ILE A 242
ALA A 245
GLN A 249
ILE A 284
PHE A 287
ARG A 290
LEU A 300
CYH A 406
 9CR  A 201 ( 4.4A)
9CR  A 201 (-3.6A)
9CR  A 201 (-4.1A)
None
9CR  A 201 (-4.7A)
9CR  A 201 (-2.8A)
9CR  A 201 (-4.4A)
9CR  A 201 (-3.6A)
 0.68A 4k6iA-1xiuA:
32.7		 4k6iA-1xiuA:
81.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xiu RXR-LIKE PROTEIN
(Biomphalaria
glabrata) 		5 / 12 LEU A 283
ILE A 284
PHE A 287
ALA A 245
VAL A 323
 9CR  A 201 ( 4.1A)
None
9CR  A 201 (-4.7A)
9CR  A 201 (-3.6A)
None
 1.02A 4k6iA-1xiuA:
32.7		 4k6iA-1xiuA:
81.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xls RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		11 / 12 ILE A 268
ALA A 271
ALA A 272
GLN A 275
LEU A 309
ILE A 310
PHE A 313
ARG A 316
LEU A 326
ALA A 327
VAL A 349
 9CR  A 801 (-3.9A)
9CR  A 801 (-3.6A)
9CR  A 801 (-3.5A)
9CR  A 801 (-4.7A)
9CR  A 801 (-4.2A)
None
9CR  A 801 (-4.3A)
9CR  A 801 (-2.6A)
9CR  A 801 (-4.1A)
9CR  A 801 (-3.3A)
None
 0.37A 4k6iA-1xlsA:
35.3		 4k6iA-1xlsA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xls RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		9 / 12 ILE A 268
ALA A 271
LEU A 309
ILE A 310
PHE A 313
ARG A 316
LEU A 326
ALA A 327
CYH A 432
 9CR  A 801 (-3.9A)
9CR  A 801 (-3.6A)
9CR  A 801 (-4.2A)
None
9CR  A 801 (-4.3A)
9CR  A 801 (-2.6A)
9CR  A 801 (-4.1A)
9CR  A 801 (-3.3A)
9CR  A 801 ( 3.7A)
 0.69A 4k6iA-1xlsA:
35.3		 4k6iA-1xlsA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xls RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		5 / 12 LEU A 309
ILE A 310
PHE A 313
ALA A 271
VAL A 349
 9CR  A 801 (-4.2A)
None
9CR  A 801 (-4.3A)
9CR  A 801 (-3.6A)
None
 1.06A 4k6iA-1xlsA:
35.3		 4k6iA-1xlsA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		9 / 12 ALA A 271
ALA A 272
GLN A 275
LEU A 309
ILE A 310
PHE A 313
ARG A 316
LEU A 326
VAL A 349
 9CR  A7223 (-3.5A)
9CR  A7223 (-4.2A)
9CR  A7223 (-4.6A)
9CR  A7223 ( 4.4A)
None
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 (-3.8A)
None
 0.51A 4k6iA-3dzuA:
33.7		 4k6iA-3dzuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		8 / 12 GLN A 275
LEU A 309
ILE A 310
PHE A 313
ARG A 316
LEU A 326
ALA A 327
VAL A 349
 9CR  A7223 (-4.6A)
9CR  A7223 ( 4.4A)
None
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
None
 0.63A 4k6iA-3dzuA:
33.7		 4k6iA-3dzuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		9 / 12 ILE A 268
ALA A 271
ALA A 272
GLN A 275
LEU A 309
ILE A 310
PHE A 313
ARG A 316
VAL A 349
 9CR  A7223 (-3.9A)
9CR  A7223 (-3.5A)
9CR  A7223 (-4.2A)
9CR  A7223 (-4.6A)
9CR  A7223 ( 4.4A)
None
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
None
 0.54A 4k6iA-3dzuA:
33.7		 4k6iA-3dzuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		5 / 12 ILE A 268
ILE A 310
PHE A 313
ARG A 316
CYH A 432
 9CR  A7223 (-3.9A)
None
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 (-3.8A)
 1.01A 4k6iA-3dzuA:
33.7		 4k6iA-3dzuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		5 / 12 ILE A 310
PHE A 313
ARG A 316
LEU A 326
CYH A 432
 None
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 (-3.8A)
9CR  A7223 (-3.8A)
 0.95A 4k6iA-3dzuA:
33.7		 4k6iA-3dzuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		5 / 12 LEU A 309
ILE A 310
PHE A 313
ALA A 271
VAL A 349
 9CR  A7223 ( 4.4A)
None
9CR  A7223 (-4.5A)
9CR  A7223 (-3.5A)
None
 1.10A 4k6iA-3dzuA:
33.7		 4k6iA-3dzuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5uan RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		12 / 12 ILE A 268
ALA A 271
ALA A 272
GLN A 275
LEU A 309
ILE A 310
PHE A 313
ARG A 316
LEU A 326
ALA A 327
VAL A 349
CYH A 432
 9CR  A 503 (-4.0A)
9CR  A 503 (-3.5A)
9CR  A 503 (-3.5A)
9CR  A 503 (-3.8A)
9CR  A 503 (-3.7A)
9CR  A 503 ( 4.8A)
9CR  A 503 (-4.7A)
9CR  A 503 (-3.0A)
9CR  A 503 (-4.3A)
9CR  A 503 (-3.4A)
None
9CR  A 503 (-3.3A)
 0.52A 4k6iA-5uanA:
34.4		 4k6iA-5uanA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NQA_A_9CRA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xiu RXR-LIKE PROTEIN
(Biomphalaria
glabrata) 		6 / 11 ILE A 242
ALA A 245
GLN A 249
PHE A 287
VAL A 316
HIS A 409
 9CR  A 201 ( 4.4A)
9CR  A 201 (-3.6A)
9CR  A 201 (-4.1A)
9CR  A 201 (-4.7A)
9CR  A 201 (-4.2A)
9CR  A 201 (-4.8A)
 1.49A 4nqaA-1xiuA:
32.0		 4nqaA-1xiuA:
62.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NQA_A_9CRA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xiu RXR-LIKE PROTEIN
(Biomphalaria
glabrata) 		10 / 11 ILE A 242
ALA A 246
GLN A 249
PHE A 287
ARG A 290
LEU A 300
ALA A 301
VAL A 316
CYH A 406
LEU A 410
 9CR  A 201 ( 4.4A)
9CR  A 201 (-3.6A)
9CR  A 201 (-4.1A)
9CR  A 201 (-4.7A)
9CR  A 201 (-2.8A)
9CR  A 201 (-4.4A)
9CR  A 201 (-3.4A)
9CR  A 201 (-4.2A)
9CR  A 201 (-3.6A)
9CR  A 201 ( 4.8A)
 0.55A 4nqaA-1xiuA:
32.0		 4nqaA-1xiuA:
62.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NQA_A_9CRA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xiu RXR-LIKE PROTEIN
(Biomphalaria
glabrata) 		10 / 11 ILE A 242
ALA A 246
GLN A 249
PHE A 287
LEU A 300
ALA A 301
VAL A 316
CYH A 406
HIS A 409
LEU A 410
 9CR  A 201 ( 4.4A)
9CR  A 201 (-3.6A)
9CR  A 201 (-4.1A)
9CR  A 201 (-4.7A)
9CR  A 201 (-4.4A)
9CR  A 201 (-3.4A)
9CR  A 201 (-4.2A)
9CR  A 201 (-3.6A)
9CR  A 201 (-4.8A)
9CR  A 201 ( 4.8A)
 0.39A 4nqaA-1xiuA:
32.0		 4nqaA-1xiuA:
62.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NQA_A_9CRA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xls RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		10 / 11 ILE A 268
ALA A 272
GLN A 275
PHE A 313
ARG A 316
LEU A 326
ALA A 327
CYH A 432
HIS A 435
LEU A 436
 9CR  A 801 (-3.9A)
9CR  A 801 (-3.5A)
9CR  A 801 (-4.7A)
9CR  A 801 (-4.3A)
9CR  A 801 (-2.6A)
9CR  A 801 (-4.1A)
9CR  A 801 (-3.3A)
9CR  A 801 ( 3.7A)
None
9CR  A 801 (-4.7A)
 0.53A 4nqaA-1xlsA:
34.0		 4nqaA-1xlsA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NQA_A_9CRA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xls RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		10 / 11 ILE A 268
ALA A 272
GLN A 275
PHE A 313
LEU A 326
ALA A 327
VAL A 342
CYH A 432
HIS A 435
LEU A 436
 9CR  A 801 (-3.9A)
9CR  A 801 (-3.5A)
9CR  A 801 (-4.7A)
9CR  A 801 (-4.3A)
9CR  A 801 (-4.1A)
9CR  A 801 (-3.3A)
9CR  A 801 ( 4.3A)
9CR  A 801 ( 3.7A)
None
9CR  A 801 (-4.7A)
 0.37A 4nqaA-1xlsA:
34.0		 4nqaA-1xlsA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NQA_A_9CRA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		10 / 11 ILE A 268
ALA A 272
GLN A 275
PHE A 313
ARG A 316
ALA A 327
VAL A 342
CYH A 432
HIS A 435
LEU A 436
 9CR  A7223 (-3.9A)
9CR  A7223 (-4.2A)
9CR  A7223 (-4.6A)
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 ( 4.7A)
9CR  A7223 ( 4.5A)
9CR  A7223 (-3.8A)
9CR  A7223 (-4.3A)
9CR  A7223 ( 4.7A)
 0.76A 4nqaA-3dzuA:
32.2		 4nqaA-3dzuA:
78.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NQA_A_9CRA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		10 / 11 ILE A 268
ALA A 272
GLN A 275
PHE A 313
LEU A 326
ALA A 327
VAL A 342
CYH A 432
HIS A 435
LEU A 436
 9CR  A7223 (-3.9A)
9CR  A7223 (-4.2A)
9CR  A7223 (-4.6A)
9CR  A7223 (-4.5A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
9CR  A7223 ( 4.5A)
9CR  A7223 (-3.8A)
9CR  A7223 (-4.3A)
9CR  A7223 ( 4.7A)
 0.74A 4nqaA-3dzuA:
32.2		 4nqaA-3dzuA:
78.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NQA_A_9CRA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5uan RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		11 / 11 ILE A 268
ALA A 272
GLN A 275
PHE A 313
ARG A 316
LEU A 326
ALA A 327
VAL A 342
CYH A 432
HIS A 435
LEU A 436
 9CR  A 503 (-4.0A)
9CR  A 503 (-3.5A)
9CR  A 503 (-3.8A)
9CR  A 503 (-4.7A)
9CR  A 503 (-3.0A)
9CR  A 503 (-4.3A)
9CR  A 503 (-3.4A)
None
9CR  A 503 (-3.3A)
None
9CR  A 503 ( 4.8A)
 0.57A 4nqaA-5uanA:
33.2		 4nqaA-5uanA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NQA_H_9CRH501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xiu RXR-LIKE PROTEIN
(Biomphalaria
glabrata) 		10 / 12 ILE A 242
ALA A 245
ALA A 246
ARG A 290
LEU A 300
ALA A 301
ILE A 319
CYH A 406
HIS A 409
LEU A 410
 9CR  A 201 ( 4.4A)
9CR  A 201 (-3.6A)
9CR  A 201 (-3.6A)
9CR  A 201 (-2.8A)
9CR  A 201 (-4.4A)
9CR  A 201 (-3.4A)
None
9CR  A 201 (-3.6A)
9CR  A 201 (-4.8A)
9CR  A 201 ( 4.8A)
 0.51A 4nqaH-1xiuA:
31.1		 4nqaH-1xiuA:
62.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NQA_H_9CRH501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xiu RXR-LIKE PROTEIN
(Biomphalaria
glabrata) 		11 / 12 ILE A 242
ALA A 245
ALA A 246
GLN A 249
PHE A 287
ARG A 290
LEU A 300
ALA A 301
CYH A 406
HIS A 409
LEU A 410
 9CR  A 201 ( 4.4A)
9CR  A 201 (-3.6A)
9CR  A 201 (-3.6A)
9CR  A 201 (-4.1A)
9CR  A 201 (-4.7A)
9CR  A 201 (-2.8A)
9CR  A 201 (-4.4A)
9CR  A 201 (-3.4A)
9CR  A 201 (-3.6A)
9CR  A 201 (-4.8A)
9CR  A 201 ( 4.8A)
 0.48A 4nqaH-1xiuA:
31.1		 4nqaH-1xiuA:
62.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NQA_H_9CRH501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xls RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		11 / 12 ILE A 268
ALA A 271
ALA A 272
GLN A 275
PHE A 313
ARG A 316
LEU A 326
ALA A 327
CYH A 432
HIS A 435
LEU A 436
 9CR  A 801 (-3.9A)
9CR  A 801 (-3.6A)
9CR  A 801 (-3.5A)
9CR  A 801 (-4.7A)
9CR  A 801 (-4.3A)
9CR  A 801 (-2.6A)
9CR  A 801 (-4.1A)
9CR  A 801 (-3.3A)
9CR  A 801 ( 3.7A)
None
9CR  A 801 (-4.7A)
 0.50A 4nqaH-1xlsA:
34.1		 4nqaH-1xlsA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NQA_H_9CRH501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xls RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		6 / 12 ILE A 268
ALA A 272
ILE A 345
CYH A 432
HIS A 435
LEU A 436
 9CR  A 801 (-3.9A)
9CR  A 801 (-3.5A)
9CR  A 801 ( 4.5A)
9CR  A 801 ( 3.7A)
None
9CR  A 801 (-4.7A)
 0.54A 4nqaH-1xlsA:
34.1		 4nqaH-1xlsA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NQA_H_9CRH501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		11 / 12 ILE A 268
ALA A 271
ALA A 272
GLN A 275
PHE A 313
ARG A 316
LEU A 326
ILE A 345
CYH A 432
HIS A 435
LEU A 436
 9CR  A7223 (-3.9A)
9CR  A7223 (-3.5A)
9CR  A7223 (-4.2A)
9CR  A7223 (-4.6A)
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.9A)
9CR  A7223 (-3.8A)
9CR  A7223 (-4.3A)
9CR  A7223 ( 4.7A)
 0.66A 4nqaH-3dzuA:
32.4		 4nqaH-3dzuA:
78.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NQA_H_9CRH501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		11 / 12 ILE A 268
ALA A 272
GLN A 275
PHE A 313
ARG A 316
LEU A 326
ALA A 327
ILE A 345
CYH A 432
HIS A 435
LEU A 436
 9CR  A7223 (-3.9A)
9CR  A7223 (-4.2A)
9CR  A7223 (-4.6A)
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
9CR  A7223 ( 4.9A)
9CR  A7223 (-3.8A)
9CR  A7223 (-4.3A)
9CR  A7223 ( 4.7A)
 0.73A 4nqaH-3dzuA:
32.4		 4nqaH-3dzuA:
78.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NQA_H_9CRH501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5uan RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		9 / 12 ILE A 268
ALA A 271
ALA A 272
ARG A 316
LEU A 326
ALA A 327
ILE A 345
CYH A 432
LEU A 436
 9CR  A 503 (-4.0A)
9CR  A 503 (-3.5A)
9CR  A 503 (-3.5A)
9CR  A 503 (-3.0A)
9CR  A 503 (-4.3A)
9CR  A 503 (-3.4A)
None
9CR  A 503 (-3.3A)
9CR  A 503 ( 4.8A)
 0.72A 4nqaH-5uanA:
33.3		 4nqaH-5uanA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NQA_H_9CRH501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5uan RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		9 / 12 ILE A 268
ALA A 271
ALA A 272
GLN A 275
PHE A 313
ARG A 316
LEU A 326
ALA A 327
LEU A 436
 9CR  A 503 (-4.0A)
9CR  A 503 (-3.5A)
9CR  A 503 (-3.5A)
9CR  A 503 (-3.8A)
9CR  A 503 (-4.7A)
9CR  A 503 (-3.0A)
9CR  A 503 (-4.3A)
9CR  A 503 (-3.4A)
9CR  A 503 ( 4.8A)
 0.62A 4nqaH-5uanA:
33.3		 4nqaH-5uanA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NQA_H_9CRH501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5uan RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		9 / 12 ILE A 268
ALA A 271
ALA A 272
GLN A 275
PHE A 313
LEU A 326
ALA A 327
HIS A 435
LEU A 436
 9CR  A 503 (-4.0A)
9CR  A 503 (-3.5A)
9CR  A 503 (-3.5A)
9CR  A 503 (-3.8A)
9CR  A 503 (-4.7A)
9CR  A 503 (-4.3A)
9CR  A 503 (-3.4A)
None
9CR  A 503 ( 4.8A)
 0.46A 4nqaH-5uanA:
33.3		 4nqaH-5uanA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NQA_H_9CRH501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5uan RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		9 / 12 ILE A 268
ALA A 271
ALA A 272
PHE A 313
ARG A 316
LEU A 326
ALA A 327
CYH A 432
LEU A 436
 9CR  A 503 (-4.0A)
9CR  A 503 (-3.5A)
9CR  A 503 (-3.5A)
9CR  A 503 (-4.7A)
9CR  A 503 (-3.0A)
9CR  A 503 (-4.3A)
9CR  A 503 (-3.4A)
9CR  A 503 (-3.3A)
9CR  A 503 ( 4.8A)
 0.64A 4nqaH-5uanA:
33.3		 4nqaH-5uanA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NQA_H_9CRH501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5uan RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		9 / 12 ILE A 268
ALA A 271
ALA A 272
PHE A 313
LEU A 326
ALA A 327
CYH A 432
HIS A 435
LEU A 436
 9CR  A 503 (-4.0A)
9CR  A 503 (-3.5A)
9CR  A 503 (-3.5A)
9CR  A 503 (-4.7A)
9CR  A 503 (-4.3A)
9CR  A 503 (-3.4A)
9CR  A 503 (-3.3A)
None
9CR  A 503 ( 4.8A)
 0.50A 4nqaH-5uanA:
33.3		 4nqaH-5uanA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PXM_B_ESTB2000_1
(ESTROGEN RECEPTOR)		 1xiu RXR-LIKE PROTEIN
(Biomphalaria
glabrata) 		5 / 11 ALA A 246
LEU A 283
ARG A 290
ILE A 402
GLY A 403
 9CR  A 201 (-3.6A)
9CR  A 201 ( 4.1A)
9CR  A 201 (-2.8A)
None
None
 0.97A 4pxmB-1xiuA:
23.3		 4pxmB-1xiuA:
28.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PXM_B_ESTB2000_1
(ESTROGEN RECEPTOR)		 1xls RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		5 / 11 ALA A 272
LEU A 309
ARG A 316
ILE A 345
LEU A 436
 9CR  A 801 (-3.5A)
9CR  A 801 (-4.2A)
9CR  A 801 (-2.6A)
9CR  A 801 ( 4.5A)
9CR  A 801 (-4.7A)
 1.02A 4pxmB-1xlsA:
25.5		 4pxmB-1xlsA:
29.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PXM_B_ESTB2000_1
(ESTROGEN RECEPTOR)		 1xls RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		5 / 11 ALA A 272
LEU A 309
ARG A 316
ILE A 428
GLY A 429
 9CR  A 801 (-3.5A)
9CR  A 801 (-4.2A)
9CR  A 801 (-2.6A)
None
None
 1.04A 4pxmB-1xlsA:
25.5		 4pxmB-1xlsA:
29.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PXM_B_ESTB2000_1
(ESTROGEN RECEPTOR)		 5uan RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		5 / 11 ALA A 272
LEU A 309
ARG A 316
ILE A 428
GLY A 429
 9CR  A 503 (-3.5A)
9CR  A 503 (-3.7A)
9CR  A 503 (-3.0A)
None
None
 1.10A 4pxmB-5uanA:
25.5		 4pxmB-5uanA:
26.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNV_D_QI9D602_0
(CYTOCHROME P450 2D6)		 5uan RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		4 / 7 PHE A 439
LEU A 436
VAL A 265
PHE A 346
 None
9CR  A 503 ( 4.8A)
None
None
 1.04A 4wnvD-5uanA:
undetectable		 4wnvD-5uanA:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_A_29SA601_1
(ESTROGEN RECEPTOR)		 1xiu RXR-LIKE PROTEIN
(Biomphalaria
glabrata) 		5 / 12 ALA A 246
ASP A 247
LEU A 250
TRP A 279
ARG A 290
 9CR  A 201 (-3.6A)
None
None
None
9CR  A 201 (-2.8A)
 1.31A 4xi3A-1xiuA:
22.5		 4xi3A-1xiuA:
29.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_A_29SA601_1
(ESTROGEN RECEPTOR)		 1xiu RXR-LIKE PROTEIN
(Biomphalaria
glabrata) 		5 / 12 ALA A 246
ASP A 247
TRP A 279
ARG A 290
LEU A 410
 9CR  A 201 (-3.6A)
None
None
9CR  A 201 (-2.8A)
9CR  A 201 ( 4.8A)
 1.12A 4xi3A-1xiuA:
22.5		 4xi3A-1xiuA:
29.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_A_29SA601_1
(ESTROGEN RECEPTOR)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		5 / 12 ALA A 272
ASP A 273
LEU A 276
TRP A 305
ARG A 316
 9CR  A7223 (-4.2A)
None
None
None
9CR  A7223 (-3.7A)
 1.30A 4xi3A-3dzuA:
22.8		 4xi3A-3dzuA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_A_29SA601_1
(ESTROGEN RECEPTOR)		 5uan RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		5 / 12 ALA A 272
ASP A 273
TRP A 305
ARG A 316
LEU A 436
 9CR  A 503 (-3.5A)
None
None
9CR  A 503 (-3.0A)
9CR  A 503 ( 4.8A)
 1.25A 4xi3A-5uanA:
22.3		 4xi3A-5uanA:
24.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_B_29SB601_1
(ESTROGEN RECEPTOR)		 1xiu RXR-LIKE PROTEIN
(Biomphalaria
glabrata) 		6 / 12 ALA A 246
ASP A 247
TRP A 279
LEU A 283
ARG A 290
LEU A 410
 9CR  A 201 (-3.6A)
None
None
9CR  A 201 ( 4.1A)
9CR  A 201 (-2.8A)
9CR  A 201 ( 4.8A)
 1.08A 4xi3B-1xiuA:
22.4		 4xi3B-1xiuA:
29.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_B_29SB601_1
(ESTROGEN RECEPTOR)		 1xiu RXR-LIKE PROTEIN
(Biomphalaria
glabrata) 		6 / 12 ALA A 246
LEU A 250
TRP A 279
ARG A 290
ILE A 402
GLY A 403
 9CR  A 201 (-3.6A)
None
None
9CR  A 201 (-2.8A)
None
None
 1.08A 4xi3B-1xiuA:
22.4		 4xi3B-1xiuA:
29.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_B_29SB601_1
(ESTROGEN RECEPTOR)		 1xiu RXR-LIKE PROTEIN
(Biomphalaria
glabrata) 		6 / 12 ALA A 246
TRP A 279
LEU A 283
ARG A 290
ILE A 402
GLY A 403
 9CR  A 201 (-3.6A)
None
9CR  A 201 ( 4.1A)
9CR  A 201 (-2.8A)
None
None
 0.95A 4xi3B-1xiuA:
22.4		 4xi3B-1xiuA:
29.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XI3_B_29SB601_1
(ESTROGEN RECEPTOR)		 1xls RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		5 / 12 ALA A 272
LEU A 309
ARG A 316
ILE A 428
GLY A 429
 9CR  A 801 (-3.5A)
9CR  A 801 (-4.2A)
9CR  A 801 (-2.6A)
None
None
 0.99A 4xi3B-1xlsA:
22.8		 4xi3B-1xlsA:
31.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XI3_B_29SB601_1
(ESTROGEN RECEPTOR)		 1xls RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		5 / 12 ALA A 272
TRP A 305
LEU A 309
ARG A 316
GLY A 429
 9CR  A 801 (-3.5A)
None
9CR  A 801 (-4.2A)
9CR  A 801 (-2.6A)
None
 0.91A 4xi3B-1xlsA:
22.8		 4xi3B-1xlsA:
31.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XI3_B_29SB601_1
(ESTROGEN RECEPTOR)		 1xls RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		5 / 12 ALA A 272
TRP A 305
LEU A 309
ARG A 316
LEU A 436
 9CR  A 801 (-3.5A)
None
9CR  A 801 (-4.2A)
9CR  A 801 (-2.6A)
9CR  A 801 (-4.7A)
 0.92A 4xi3B-1xlsA:
22.8		 4xi3B-1xlsA:
31.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XI3_B_29SB601_1
(ESTROGEN RECEPTOR)		 1xls RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		5 / 12 ALA A 272
TRP A 305
LEU A 309
ILE A 345
LEU A 436
 9CR  A 801 (-3.5A)
None
9CR  A 801 (-4.2A)
9CR  A 801 ( 4.5A)
9CR  A 801 (-4.7A)
 0.86A 4xi3B-1xlsA:
22.8		 4xi3B-1xlsA:
31.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_B_29SB601_1
(ESTROGEN RECEPTOR)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		6 / 12 ALA A 272
ASP A 273
LEU A 276
TRP A 305
LEU A 309
ARG A 316
 9CR  A7223 (-4.2A)
None
None
None
9CR  A7223 ( 4.4A)
9CR  A7223 (-3.7A)
 1.25A 4xi3B-3dzuA:
22.7		 4xi3B-3dzuA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_B_29SB601_1
(ESTROGEN RECEPTOR)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		6 / 12 ALA A 272
ASP A 273
TRP A 305
LEU A 309
ARG A 316
LEU A 436
 9CR  A7223 (-4.2A)
None
None
9CR  A7223 ( 4.4A)
9CR  A7223 (-3.7A)
9CR  A7223 ( 4.7A)
 1.04A 4xi3B-3dzuA:
22.7		 4xi3B-3dzuA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_B_29SB601_1
(ESTROGEN RECEPTOR)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		7 / 12 ALA A 272
LEU A 276
TRP A 305
LEU A 309
ARG A 316
ILE A 428
GLY A 429
 9CR  A7223 (-4.2A)
None
None
9CR  A7223 ( 4.4A)
9CR  A7223 (-3.7A)
None
None
 1.03A 4xi3B-3dzuA:
22.7		 4xi3B-3dzuA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_B_29SB601_1
(ESTROGEN RECEPTOR)		 5uan RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		6 / 12 ALA A 272
ASP A 273
TRP A 305
LEU A 309
ARG A 316
LEU A 436
 9CR  A 503 (-3.5A)
None
None
9CR  A 503 (-3.7A)
9CR  A 503 (-3.0A)
9CR  A 503 ( 4.8A)
 1.21A 4xi3B-5uanA:
22.3		 4xi3B-5uanA:
24.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_B_29SB601_1
(ESTROGEN RECEPTOR)		 5uan RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		6 / 12 ALA A 272
TRP A 305
LEU A 309
ARG A 316
ILE A 428
GLY A 429
 9CR  A 503 (-3.5A)
None
9CR  A 503 (-3.7A)
9CR  A 503 (-3.0A)
None
None
 1.10A 4xi3B-5uanA:
22.3		 4xi3B-5uanA:
24.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_C_29SC601_1
(ESTROGEN RECEPTOR)		 1xiu RXR-LIKE PROTEIN
(Biomphalaria
glabrata) 		5 / 12 ALA A 246
LEU A 250
TRP A 279
ARG A 290
GLY A 403
 9CR  A 201 (-3.6A)
None
None
9CR  A 201 (-2.8A)
None
 0.96A 4xi3C-1xiuA:
22.3		 4xi3C-1xiuA:
29.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_C_29SC601_1
(ESTROGEN RECEPTOR)		 1xiu RXR-LIKE PROTEIN
(Biomphalaria
glabrata) 		5 / 12 ALA A 246
TRP A 279
LEU A 283
ARG A 290
GLY A 403
 9CR  A 201 (-3.6A)
None
9CR  A 201 ( 4.1A)
9CR  A 201 (-2.8A)
None
 0.80A 4xi3C-1xiuA:
22.3		 4xi3C-1xiuA:
29.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_C_29SC601_1
(ESTROGEN RECEPTOR)		 1xiu RXR-LIKE PROTEIN
(Biomphalaria
glabrata) 		5 / 12 ALA A 246
TRP A 279
LEU A 283
ARG A 290
LEU A 410
 9CR  A 201 (-3.6A)
None
9CR  A 201 ( 4.1A)
9CR  A 201 (-2.8A)
9CR  A 201 ( 4.8A)
 0.96A 4xi3C-1xiuA:
22.3		 4xi3C-1xiuA:
29.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XI3_C_29SC601_1
(ESTROGEN RECEPTOR)		 1xls RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		5 / 12 ALA A 272
TRP A 305
LEU A 309
ARG A 316
GLY A 429
 9CR  A 801 (-3.5A)
None
9CR  A 801 (-4.2A)
9CR  A 801 (-2.6A)
None
 0.91A 4xi3C-1xlsA:
22.2		 4xi3C-1xlsA:
31.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XI3_C_29SC601_1
(ESTROGEN RECEPTOR)		 1xls RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		5 / 12 ALA A 272
TRP A 305
LEU A 309
ARG A 316
LEU A 436
 9CR  A 801 (-3.5A)
None
9CR  A 801 (-4.2A)
9CR  A 801 (-2.6A)
9CR  A 801 (-4.7A)
 0.92A 4xi3C-1xlsA:
22.2		 4xi3C-1xlsA:
31.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_C_29SC601_1
(ESTROGEN RECEPTOR)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		6 / 12 ALA A 272
LEU A 276
TRP A 305
LEU A 309
ARG A 316
GLY A 429
 9CR  A7223 (-4.2A)
None
None
9CR  A7223 ( 4.4A)
9CR  A7223 (-3.7A)
None
 0.92A 4xi3C-3dzuA:
22.5		 4xi3C-3dzuA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_C_29SC601_1
(ESTROGEN RECEPTOR)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		5 / 12 ALA A 272
TRP A 305
LEU A 309
ARG A 316
LEU A 436
 9CR  A7223 (-4.2A)
None
9CR  A7223 ( 4.4A)
9CR  A7223 (-3.7A)
9CR  A7223 ( 4.7A)
 0.85A 4xi3C-3dzuA:
22.5		 4xi3C-3dzuA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_C_29SC601_1
(ESTROGEN RECEPTOR)		 5uan RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		5 / 12 ALA A 272
TRP A 305
LEU A 309
ARG A 316
GLY A 429
 9CR  A 503 (-3.5A)
None
9CR  A 503 (-3.7A)
9CR  A 503 (-3.0A)
None
 0.99A 4xi3C-5uanA:
21.8		 4xi3C-5uanA:
24.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_D_29SD601_1
(ESTROGEN RECEPTOR)		 1xiu RXR-LIKE PROTEIN
(Biomphalaria
glabrata) 		5 / 12 ALA A 246
TRP A 279
LEU A 283
ARG A 290
LEU A 410
 9CR  A 201 (-3.6A)
None
9CR  A 201 ( 4.1A)
9CR  A 201 (-2.8A)
9CR  A 201 ( 4.8A)
 0.97A 4xi3D-1xiuA:
22.6		 4xi3D-1xiuA:
29.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XI3_D_29SD601_1
(ESTROGEN RECEPTOR)		 1xls RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		5 / 12 ALA A 272
TRP A 305
LEU A 309
ARG A 316
LEU A 436
 9CR  A 801 (-3.5A)
None
9CR  A 801 (-4.2A)
9CR  A 801 (-2.6A)
9CR  A 801 (-4.7A)
 0.91A 4xi3D-1xlsA:
22.4		 4xi3D-1xlsA:
31.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_D_29SD601_1
(ESTROGEN RECEPTOR)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		5 / 12 ALA A 272
TRP A 305
LEU A 309
ARG A 316
LEU A 436
 9CR  A7223 (-4.2A)
None
9CR  A7223 ( 4.4A)
9CR  A7223 (-3.7A)
9CR  A7223 ( 4.7A)
 0.85A 4xi3D-3dzuA:
22.9		 4xi3D-3dzuA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXB_B_ESTB601_1
(ESTROGEN RECEPTOR)		 1xiu RXR-LIKE PROTEIN
(Biomphalaria
glabrata) 		5 / 11 ALA A 246
LEU A 283
ARG A 290
ILE A 402
GLY A 403
 9CR  A 201 (-3.6A)
9CR  A 201 ( 4.1A)
9CR  A 201 (-2.8A)
None
None
 0.98A 5dxbB-1xiuA:
23.2		 5dxbB-1xiuA:
28.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXB_B_ESTB601_1
(ESTROGEN RECEPTOR)		 1xls RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		5 / 11 ALA A 272
LEU A 309
ARG A 316
ILE A 345
LEU A 436
 9CR  A 801 (-3.5A)
9CR  A 801 (-4.2A)
9CR  A 801 (-2.6A)
9CR  A 801 ( 4.5A)
9CR  A 801 (-4.7A)
 1.02A 5dxbB-1xlsA:
25.6		 5dxbB-1xlsA:
29.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXB_B_ESTB601_1
(ESTROGEN RECEPTOR)		 1xls RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		5 / 11 ALA A 272
LEU A 309
ARG A 316
ILE A 428
GLY A 429
 9CR  A 801 (-3.5A)
9CR  A 801 (-4.2A)
9CR  A 801 (-2.6A)
None
None
 1.03A 5dxbB-1xlsA:
25.6		 5dxbB-1xlsA:
29.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JI0_A_9CRA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xiu RXR-LIKE PROTEIN
(Biomphalaria
glabrata) 		11 / 11 ILE A 242
GLN A 249
TRP A 279
LEU A 283
PHE A 287
ARG A 290
LEU A 300
ALA A 301
VAL A 316
CYH A 406
LEU A 410
 9CR  A 201 ( 4.4A)
9CR  A 201 (-4.1A)
None
9CR  A 201 ( 4.1A)
9CR  A 201 (-4.7A)
9CR  A 201 (-2.8A)
9CR  A 201 (-4.4A)
9CR  A 201 (-3.4A)
9CR  A 201 (-4.2A)
9CR  A 201 (-3.6A)
9CR  A 201 ( 4.8A)
 0.32A 5ji0A-1xiuA:
32.7		 5ji0A-1xiuA:
79.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JI0_A_9CRA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xls RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		11 / 11 ILE A 268
GLN A 275
TRP A 305
LEU A 309
PHE A 313
ARG A 316
LEU A 326
ALA A 327
VAL A 342
CYH A 432
LEU A 436
 9CR  A 801 (-3.9A)
9CR  A 801 (-4.7A)
None
9CR  A 801 (-4.2A)
9CR  A 801 (-4.3A)
9CR  A 801 (-2.6A)
9CR  A 801 (-4.1A)
9CR  A 801 (-3.3A)
9CR  A 801 ( 4.3A)
9CR  A 801 ( 3.7A)
9CR  A 801 (-4.7A)
 0.34A 5ji0A-1xlsA:
34.7		 5ji0A-1xlsA:
99.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JI0_A_9CRA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		11 / 11 ILE A 268
GLN A 275
TRP A 305
LEU A 309
PHE A 313
ARG A 316
LEU A 326
ALA A 327
VAL A 342
CYH A 432
LEU A 436
 9CR  A7223 (-3.9A)
9CR  A7223 (-4.6A)
None
9CR  A7223 ( 4.4A)
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
9CR  A7223 ( 4.5A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
 0.62A 5ji0A-3dzuA:
33.8		 5ji0A-3dzuA:
59.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JI0_A_9CRA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5uan RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		11 / 11 ILE A 268
GLN A 275
TRP A 305
LEU A 309
PHE A 313
ARG A 316
LEU A 326
ALA A 327
VAL A 342
CYH A 432
LEU A 436
 9CR  A 503 (-4.0A)
9CR  A 503 (-3.8A)
None
9CR  A 503 (-3.7A)
9CR  A 503 (-4.7A)
9CR  A 503 (-3.0A)
9CR  A 503 (-4.3A)
9CR  A 503 (-3.4A)
None
9CR  A 503 (-3.3A)
9CR  A 503 ( 4.8A)
 0.64A 5ji0A-5uanA:
32.7		 5ji0A-5uanA:
91.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5M24_A_9CRA501_1
(RETINOIC ACID
RECEPTOR GAMMA)		 1xdk RETINOIC ACID
RECEPTOR, BETA
(Mus
musculus) 		11 / 12 TRP B 218
PHE B 221
ALA B 225
LEU B 262
ILE B 266
ARG B 269
SER B 280
PHE B 295
GLY B 384
LEU B 391
ILE B 403
 None
9CR  B 600 ( 4.7A)
9CR  B 600 (-3.8A)
9CR  B 600 (-3.9A)
9CR  B 600 ( 3.8A)
9CR  B 600 (-3.8A)
9CR  B 600 (-3.0A)
9CR  B 600 (-3.9A)
9CR  B 600 ( 4.6A)
None
9CR  B 600 ( 4.4A)
 0.49A 5m24A-1xdkB:
37.5		 5m24A-1xdkB:
79.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5UAN_A_9CRA503_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xiu RXR-LIKE PROTEIN
(Biomphalaria
glabrata) 		12 / 12 ILE A 242
ALA A 245
ALA A 246
GLN A 249
TRP A 279
PHE A 287
ARG A 290
LEU A 300
ALA A 301
VAL A 316
CYH A 406
LEU A 410
 9CR  A 201 ( 4.4A)
9CR  A 201 (-3.6A)
9CR  A 201 (-3.6A)
9CR  A 201 (-4.1A)
None
9CR  A 201 (-4.7A)
9CR  A 201 (-2.8A)
9CR  A 201 (-4.4A)
9CR  A 201 (-3.4A)
9CR  A 201 (-4.2A)
9CR  A 201 (-3.6A)
9CR  A 201 ( 4.8A)
 0.51A 5uanA-1xiuA:
30.3		 5uanA-1xiuA:
62.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5UAN_A_9CRA503_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xls RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		12 / 12 ILE A 268
ALA A 271
ALA A 272
GLN A 275
TRP A 305
PHE A 313
ARG A 316
LEU A 326
ALA A 327
VAL A 342
CYH A 432
LEU A 436
 9CR  A 801 (-3.9A)
9CR  A 801 (-3.6A)
9CR  A 801 (-3.5A)
9CR  A 801 (-4.7A)
None
9CR  A 801 (-4.3A)
9CR  A 801 (-2.6A)
9CR  A 801 (-4.1A)
9CR  A 801 (-3.3A)
9CR  A 801 ( 4.3A)
9CR  A 801 ( 3.7A)
9CR  A 801 (-4.7A)
 0.52A 5uanA-1xlsA:
33.1		 5uanA-1xlsA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5UAN_A_9CRA503_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		12 / 12 ILE A 268
ALA A 271
ALA A 272
GLN A 275
TRP A 305
PHE A 313
ARG A 316
LEU A 326
ALA A 327
VAL A 342
CYH A 432
LEU A 436
 9CR  A7223 (-3.9A)
9CR  A7223 (-3.5A)
9CR  A7223 (-4.2A)
9CR  A7223 (-4.6A)
None
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
9CR  A7223 ( 4.5A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
 0.81A 5uanA-3dzuA:
32.9		 5uanA-3dzuA:
78.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5UAN_B_REAB503_1
(RETINOIC ACID
RECEPTOR BETA)		 1xdk RETINOIC ACID
RECEPTOR, BETA
(Mus
musculus) 		12 / 12 PHE B 221
ALA B 225
CYH B 228
LEU B 259
LEU B 262
ILE B 263
ILE B 266
PHE B 279
SER B 280
PHE B 295
LEU B 298
VAL B 388
 9CR  B 600 ( 4.7A)
9CR  B 600 (-3.8A)
9CR  B 600 (-3.4A)
None
9CR  B 600 (-3.9A)
9CR  B 600 (-4.0A)
9CR  B 600 ( 3.8A)
9CR  B 600 (-4.5A)
9CR  B 600 (-3.0A)
9CR  B 600 (-3.9A)
9CR  B 600 (-4.7A)
9CR  B 600 ( 4.6A)
 0.43A 5uanB-1xdkB:
38.3		 5uanB-1xdkB:
98.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5UAN_B_REAB503_1
(RETINOIC ACID
RECEPTOR BETA)		 1xdk RETINOIC ACID
RECEPTOR, BETA
(Mus
musculus) 		5 / 12 PHE B 221
CYH B 228
LEU B 407
PHE B 279
PHE B 295
 9CR  B 600 ( 4.7A)
9CR  B 600 (-3.4A)
None
9CR  B 600 (-4.5A)
9CR  B 600 (-3.9A)
 1.33A 5uanB-1xdkB:
38.3		 5uanB-1xdkB:
98.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z12_B_9CRB501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xiu RXR-LIKE PROTEIN
(Biomphalaria
glabrata) 		12 / 12 ILE A 242
ALA A 245
ALA A 246
TRP A 279
LEU A 283
PHE A 287
ARG A 290
LEU A 300
ALA A 301
VAL A 316
CYH A 406
LEU A 410
 9CR  A 201 ( 4.4A)
9CR  A 201 (-3.6A)
9CR  A 201 (-3.6A)
None
9CR  A 201 ( 4.1A)
9CR  A 201 (-4.7A)
9CR  A 201 (-2.8A)
9CR  A 201 (-4.4A)
9CR  A 201 (-3.4A)
9CR  A 201 (-4.2A)
9CR  A 201 (-3.6A)
9CR  A 201 ( 4.8A)
 0.36A 5z12B-1xiuA:
32.8		 5z12B-1xiuA:
73.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z12_B_9CRB501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xls RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		12 / 12 ILE A 268
ALA A 271
ALA A 272
TRP A 305
LEU A 309
PHE A 313
ARG A 316
LEU A 326
ALA A 327
VAL A 342
CYH A 432
LEU A 436
 9CR  A 801 (-3.9A)
9CR  A 801 (-3.6A)
9CR  A 801 (-3.5A)
None
9CR  A 801 (-4.2A)
9CR  A 801 (-4.3A)
9CR  A 801 (-2.6A)
9CR  A 801 (-4.1A)
9CR  A 801 (-3.3A)
9CR  A 801 ( 4.3A)
9CR  A 801 ( 3.7A)
9CR  A 801 (-4.7A)
 0.33A 5z12B-1xlsA:
35.4		 5z12B-1xlsA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z12_B_9CRB501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		12 / 12 ILE A 268
ALA A 271
ALA A 272
TRP A 305
LEU A 309
PHE A 313
ARG A 316
LEU A 326
ALA A 327
VAL A 342
CYH A 432
LEU A 436
 9CR  A7223 (-3.9A)
9CR  A7223 (-3.5A)
9CR  A7223 (-4.2A)
None
9CR  A7223 ( 4.4A)
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
9CR  A7223 ( 4.5A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
 0.60A 5z12B-3dzuA:
33.8		 5z12B-3dzuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z12_B_9CRB501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5uan RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		12 / 12 ILE A 268
ALA A 271
ALA A 272
TRP A 305
LEU A 309
PHE A 313
ARG A 316
LEU A 326
ALA A 327
VAL A 342
CYH A 432
LEU A 436
 9CR  A 503 (-4.0A)
9CR  A 503 (-3.5A)
9CR  A 503 (-3.5A)
None
9CR  A 503 (-3.7A)
9CR  A 503 (-4.7A)
9CR  A 503 (-3.0A)
9CR  A 503 (-4.3A)
9CR  A 503 (-3.4A)
None
9CR  A 503 (-3.3A)
9CR  A 503 ( 4.8A)
 0.53A 5z12B-5uanA:
34.4		 5z12B-5uanA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z12_B_9CRB501_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xiu RXR-LIKE PROTEIN
(Biomphalaria
glabrata) 		3 / 3 GLN A 249
ILE A 319
HIS A 409
 9CR  A 201 (-4.1A)
None
9CR  A 201 (-4.8A)
 0.39A 5z12B-1xiuA:
32.8		 5z12B-1xiuA:
73.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z12_B_9CRB501_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xls RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		3 / 3 GLN A 275
ILE A 345
HIS A 435
 9CR  A 801 (-4.7A)
9CR  A 801 ( 4.5A)
None
 0.49A 5z12B-1xlsA:
35.4		 5z12B-1xlsA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z12_B_9CRB501_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		3 / 3 GLN A 275
ILE A 345
HIS A 435
 9CR  A7223 (-4.6A)
9CR  A7223 ( 4.9A)
9CR  A7223 (-4.3A)
 0.38A 5z12B-3dzuA:
33.8		 5z12B-3dzuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z12_B_9CRB501_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5uan RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		3 / 3 GLN A 275
ILE A 345
HIS A 435
 9CR  A 503 (-3.8A)
None
None
 0.43A 5z12B-5uanA:
34.4		 5z12B-5uanA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z12_C_9CRC501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xiu RXR-LIKE PROTEIN
(Biomphalaria
glabrata) 		12 / 12 ILE A 242
ALA A 245
ALA A 246
GLN A 249
TRP A 279
PHE A 287
ARG A 290
LEU A 300
ALA A 301
VAL A 316
CYH A 406
LEU A 410
 9CR  A 201 ( 4.4A)
9CR  A 201 (-3.6A)
9CR  A 201 (-3.6A)
9CR  A 201 (-4.1A)
None
9CR  A 201 (-4.7A)
9CR  A 201 (-2.8A)
9CR  A 201 (-4.4A)
9CR  A 201 (-3.4A)
9CR  A 201 (-4.2A)
9CR  A 201 (-3.6A)
9CR  A 201 ( 4.8A)
 0.47A 5z12C-1xiuA:
30.6		 5z12C-1xiuA:
73.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z12_C_9CRC501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xls RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		12 / 12 ILE A 268
ALA A 271
ALA A 272
GLN A 275
TRP A 305
PHE A 313
ARG A 316
LEU A 326
ALA A 327
VAL A 342
CYH A 432
LEU A 436
 9CR  A 801 (-3.9A)
9CR  A 801 (-3.6A)
9CR  A 801 (-3.5A)
9CR  A 801 (-4.7A)
None
9CR  A 801 (-4.3A)
9CR  A 801 (-2.6A)
9CR  A 801 (-4.1A)
9CR  A 801 (-3.3A)
9CR  A 801 ( 4.3A)
9CR  A 801 ( 3.7A)
9CR  A 801 (-4.7A)
 0.42A 5z12C-1xlsA:
33.0		 5z12C-1xlsA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z12_C_9CRC501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		12 / 12 ILE A 268
ALA A 271
ALA A 272
GLN A 275
TRP A 305
PHE A 313
ARG A 316
LEU A 326
ALA A 327
VAL A 342
CYH A 432
LEU A 436
 9CR  A7223 (-3.9A)
9CR  A7223 (-3.5A)
9CR  A7223 (-4.2A)
9CR  A7223 (-4.6A)
None
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
9CR  A7223 ( 4.5A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
 0.70A 5z12C-3dzuA:
33.0		 5z12C-3dzuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z12_C_9CRC501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5uan RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		12 / 12 ILE A 268
ALA A 271
ALA A 272
GLN A 275
TRP A 305
PHE A 313
ARG A 316
LEU A 326
ALA A 327
VAL A 342
CYH A 432
LEU A 436
 9CR  A 503 (-4.0A)
9CR  A 503 (-3.5A)
9CR  A 503 (-3.5A)
9CR  A 503 (-3.8A)
None
9CR  A 503 (-4.7A)
9CR  A 503 (-3.0A)
9CR  A 503 (-4.3A)
9CR  A 503 (-3.4A)
None
9CR  A 503 (-3.3A)
9CR  A 503 ( 4.8A)
 0.68A 5z12C-5uanA:
33.3		 5z12C-5uanA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6A5Y_D_9CRD501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xiu RXR-LIKE PROTEIN
(Biomphalaria
glabrata) 		10 / 12 ALA A 245
ALA A 246
GLN A 249
TRP A 279
PHE A 287
ARG A 290
LEU A 300
ALA A 301
ILE A 402
CYH A 406
 9CR  A 201 (-3.6A)
9CR  A 201 (-3.6A)
9CR  A 201 (-4.1A)
None
9CR  A 201 (-4.7A)
9CR  A 201 (-2.8A)
9CR  A 201 (-4.4A)
9CR  A 201 (-3.4A)
None
9CR  A 201 (-3.6A)
 1.48A 6a5yD-1xiuA:
32.3		 6a5yD-1xiuA:
75.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6A5Y_D_9CRD501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xiu RXR-LIKE PROTEIN
(Biomphalaria
glabrata) 		12 / 12 ILE A 242
ALA A 245
ALA A 246
GLN A 249
TRP A 279
PHE A 287
ARG A 290
LEU A 300
ALA A 301
ILE A 319
CYH A 406
LEU A 410
 9CR  A 201 ( 4.4A)
9CR  A 201 (-3.6A)
9CR  A 201 (-3.6A)
9CR  A 201 (-4.1A)
None
9CR  A 201 (-4.7A)
9CR  A 201 (-2.8A)
9CR  A 201 (-4.4A)
9CR  A 201 (-3.4A)
None
9CR  A 201 (-3.6A)
9CR  A 201 ( 4.8A)
 0.45A 6a5yD-1xiuA:
32.3		 6a5yD-1xiuA:
75.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6A5Y_D_9CRD501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xls RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		6 / 12 ALA A 271
ALA A 272
GLN A 275
TRP A 305
ALA A 327
LEU A 455
 9CR  A 801 (-3.6A)
9CR  A 801 (-3.5A)
9CR  A 801 (-4.7A)
None
9CR  A 801 (-3.3A)
None
 1.32A 6a5yD-1xlsA:
34.9		 6a5yD-1xlsA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6A5Y_D_9CRD501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xls RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		12 / 12 ILE A 268
ALA A 271
ALA A 272
GLN A 275
TRP A 305
PHE A 313
ARG A 316
LEU A 326
ALA A 327
ILE A 345
CYH A 432
LEU A 436
 9CR  A 801 (-3.9A)
9CR  A 801 (-3.6A)
9CR  A 801 (-3.5A)
9CR  A 801 (-4.7A)
None
9CR  A 801 (-4.3A)
9CR  A 801 (-2.6A)
9CR  A 801 (-4.1A)
9CR  A 801 (-3.3A)
9CR  A 801 ( 4.5A)
9CR  A 801 ( 3.7A)
9CR  A 801 (-4.7A)
 0.40A 6a5yD-1xlsA:
34.9		 6a5yD-1xlsA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6A5Y_D_9CRD501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		10 / 12 ALA A 271
ALA A 272
GLN A 275
TRP A 305
PHE A 313
ARG A 316
LEU A 326
ALA A 327
ILE A 428
CYH A 432
 9CR  A7223 (-3.5A)
9CR  A7223 (-4.2A)
9CR  A7223 (-4.6A)
None
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
None
9CR  A7223 (-3.8A)
 1.45A 6a5yD-3dzuA:
34.1		 6a5yD-3dzuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6A5Y_D_9CRD501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		12 / 12 ILE A 268
ALA A 271
ALA A 272
GLN A 275
TRP A 305
PHE A 313
ARG A 316
LEU A 326
ALA A 327
ILE A 345
CYH A 432
LEU A 436
 9CR  A7223 (-3.9A)
9CR  A7223 (-3.5A)
9CR  A7223 (-4.2A)
9CR  A7223 (-4.6A)
None
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
9CR  A7223 ( 4.9A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
 0.68A 6a5yD-3dzuA:
34.1		 6a5yD-3dzuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6A5Y_D_9CRD501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5uan RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		8 / 12 ALA A 271
ALA A 272
GLN A 275
PHE A 313
ARG A 316
LEU A 326
ALA A 327
ILE A 428
 9CR  A 503 (-3.5A)
9CR  A 503 (-3.5A)
9CR  A 503 (-3.8A)
9CR  A 503 (-4.7A)
9CR  A 503 (-3.0A)
9CR  A 503 (-4.3A)
9CR  A 503 (-3.4A)
None
 1.34A 6a5yD-5uanA:
34.7		 6a5yD-5uanA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6A5Y_D_9CRD501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5uan RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		12 / 12 ILE A 268
ALA A 271
ALA A 272
GLN A 275
TRP A 305
PHE A 313
ARG A 316
LEU A 326
ALA A 327
ILE A 345
CYH A 432
LEU A 436
 9CR  A 503 (-4.0A)
9CR  A 503 (-3.5A)
9CR  A 503 (-3.5A)
9CR  A 503 (-3.8A)
None
9CR  A 503 (-4.7A)
9CR  A 503 (-3.0A)
9CR  A 503 (-4.3A)
9CR  A 503 (-3.4A)
None
9CR  A 503 (-3.3A)
9CR  A 503 ( 4.8A)
 0.60A 6a5yD-5uanA:
34.7		 6a5yD-5uanA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6A5Y_D_9CRD501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xiu RXR-LIKE PROTEIN
(Biomphalaria
glabrata) 		3 / 3 ASN A 280
VAL A 316
HIS A 409
 None
9CR  A 201 (-4.2A)
9CR  A 201 (-4.8A)
 0.33A 6a5yD-1xiuA:
32.3		 6a5yD-1xiuA:
75.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6A5Y_D_9CRD501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xls RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		3 / 3 ASN A 306
VAL A 342
HIS A 435
 None
9CR  A 801 ( 4.3A)
None
 0.24A 6a5yD-1xlsA:
34.9		 6a5yD-1xlsA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6A5Z_D_9CRD501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xiu RXR-LIKE PROTEIN
(Biomphalaria
glabrata) 		12 / 12 ILE A 242
ALA A 245
ALA A 246
GLN A 249
ILE A 284
PHE A 287
ARG A 290
LEU A 300
ALA A 301
ILE A 319
CYH A 406
LEU A 410
 9CR  A 201 ( 4.4A)
9CR  A 201 (-3.6A)
9CR  A 201 (-3.6A)
9CR  A 201 (-4.1A)
None
9CR  A 201 (-4.7A)
9CR  A 201 (-2.8A)
9CR  A 201 (-4.4A)
9CR  A 201 (-3.4A)
None
9CR  A 201 (-3.6A)
9CR  A 201 ( 4.8A)
 0.39A 6a5zD-1xiuA:
33.0		 6a5zD-1xiuA:
75.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6A5Z_D_9CRD501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xls RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		12 / 12 ILE A 268
ALA A 271
ALA A 272
GLN A 275
ILE A 310
PHE A 313
ARG A 316
LEU A 326
ALA A 327
ILE A 345
CYH A 432
LEU A 436
 9CR  A 801 (-3.9A)
9CR  A 801 (-3.6A)
9CR  A 801 (-3.5A)
9CR  A 801 (-4.7A)
None
9CR  A 801 (-4.3A)
9CR  A 801 (-2.6A)
9CR  A 801 (-4.1A)
9CR  A 801 (-3.3A)
9CR  A 801 ( 4.5A)
9CR  A 801 ( 3.7A)
9CR  A 801 (-4.7A)
 0.31A 6a5zD-1xlsA:
35.4		 6a5zD-1xlsA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6A5Z_D_9CRD501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		10 / 12 ALA A 271
ALA A 272
GLN A 275
ILE A 310
PHE A 313
ARG A 316
LEU A 326
ILE A 345
CYH A 432
LEU A 436
 9CR  A7223 (-3.5A)
9CR  A7223 (-4.2A)
9CR  A7223 (-4.6A)
None
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.9A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
 0.53A 6a5zD-3dzuA:
34.2		 6a5zD-3dzuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6A5Z_D_9CRD501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		9 / 12 ALA A 272
GLN A 275
ILE A 310
PHE A 313
ARG A 316
LEU A 326
ALA A 327
CYH A 432
LEU A 436
 9CR  A7223 (-4.2A)
9CR  A7223 (-4.6A)
None
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
 0.55A 6a5zD-3dzuA:
34.2		 6a5zD-3dzuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6A5Z_D_9CRD501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		10 / 12 ILE A 268
ALA A 271
ALA A 272
GLN A 275
ILE A 310
PHE A 313
ARG A 316
ILE A 345
CYH A 432
LEU A 436
 9CR  A7223 (-3.9A)
9CR  A7223 (-3.5A)
9CR  A7223 (-4.2A)
9CR  A7223 (-4.6A)
None
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 ( 4.9A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
 0.50A 6a5zD-3dzuA:
34.2		 6a5zD-3dzuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6A5Z_D_9CRD501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5uan RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		11 / 12 ILE A 268
ALA A 271
ALA A 272
GLN A 275
ILE A 310
PHE A 313
ARG A 316
LEU A 326
ALA A 327
ILE A 345
LEU A 436
 9CR  A 503 (-4.0A)
9CR  A 503 (-3.5A)
9CR  A 503 (-3.5A)
9CR  A 503 (-3.8A)
9CR  A 503 ( 4.8A)
9CR  A 503 (-4.7A)
9CR  A 503 (-3.0A)
9CR  A 503 (-4.3A)
9CR  A 503 (-3.4A)
None
9CR  A 503 ( 4.8A)
 0.45A 6a5zD-5uanA:
34.6		 6a5zD-5uanA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6A5Z_D_9CRD501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5uan RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		10 / 12 ILE A 268
ALA A 271
ALA A 272
ILE A 310
PHE A 313
ARG A 316
LEU A 326
ALA A 327
CYH A 432
LEU A 436
 9CR  A 503 (-4.0A)
9CR  A 503 (-3.5A)
9CR  A 503 (-3.5A)
9CR  A 503 ( 4.8A)
9CR  A 503 (-4.7A)
9CR  A 503 (-3.0A)
9CR  A 503 (-4.3A)
9CR  A 503 (-3.4A)
9CR  A 503 (-3.3A)
9CR  A 503 ( 4.8A)
 0.52A 6a5zD-5uanA:
34.6		 6a5zD-5uanA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6A5Z_L_9CRL501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xiu RXR-LIKE PROTEIN
(Biomphalaria
glabrata) 		12 / 12 ILE A 242
ALA A 245
ALA A 246
GLN A 249
PHE A 287
ARG A 290
LEU A 300
ALA A 301
ILE A 319
CYH A 406
HIS A 409
LEU A 410
 9CR  A 201 ( 4.4A)
9CR  A 201 (-3.6A)
9CR  A 201 (-3.6A)
9CR  A 201 (-4.1A)
9CR  A 201 (-4.7A)
9CR  A 201 (-2.8A)
9CR  A 201 (-4.4A)
9CR  A 201 (-3.4A)
None
9CR  A 201 (-3.6A)
9CR  A 201 (-4.8A)
9CR  A 201 ( 4.8A)
 0.40A 6a5zL-1xiuA:
32.3		 6a5zL-1xiuA:
75.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6A5Z_L_9CRL501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xls RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		12 / 12 ILE A 268
ALA A 271
ALA A 272
GLN A 275
PHE A 313
ARG A 316
LEU A 326
ALA A 327
ILE A 345
CYH A 432
HIS A 435
LEU A 436
 9CR  A 801 (-3.9A)
9CR  A 801 (-3.6A)
9CR  A 801 (-3.5A)
9CR  A 801 (-4.7A)
9CR  A 801 (-4.3A)
9CR  A 801 (-2.6A)
9CR  A 801 (-4.1A)
9CR  A 801 (-3.3A)
9CR  A 801 ( 4.5A)
9CR  A 801 ( 3.7A)
None
9CR  A 801 (-4.7A)
 0.34A 6a5zL-1xlsA:
34.7		 6a5zL-1xlsA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6A5Z_L_9CRL501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		12 / 12 ILE A 268
ALA A 271
ALA A 272
GLN A 275
PHE A 313
ARG A 316
LEU A 326
ALA A 327
ILE A 345
CYH A 432
HIS A 435
LEU A 436
 9CR  A7223 (-3.9A)
9CR  A7223 (-3.5A)
9CR  A7223 (-4.2A)
9CR  A7223 (-4.6A)
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 (-3.8A)
9CR  A7223 ( 4.7A)
9CR  A7223 ( 4.9A)
9CR  A7223 (-3.8A)
9CR  A7223 (-4.3A)
9CR  A7223 ( 4.7A)
 0.68A 6a5zL-3dzuA:
34.0		 6a5zL-3dzuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6A5Z_L_9CRL501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5uan RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		8 / 12 ALA A 271
ALA A 272
GLN A 275
PHE A 313
ARG A 316
LEU A 326
ALA A 327
ILE A 428
 9CR  A 503 (-3.5A)
9CR  A 503 (-3.5A)
9CR  A 503 (-3.8A)
9CR  A 503 (-4.7A)
9CR  A 503 (-3.0A)
9CR  A 503 (-4.3A)
9CR  A 503 (-3.4A)
None
 1.40A 6a5zL-5uanA:
34.4		 6a5zL-5uanA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6A5Z_L_9CRL501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5uan RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		12 / 12 ILE A 268
ALA A 271
ALA A 272
GLN A 275
PHE A 313
ARG A 316
LEU A 326
ALA A 327
ILE A 345
CYH A 432
HIS A 435
LEU A 436
 9CR  A 503 (-4.0A)
9CR  A 503 (-3.5A)
9CR  A 503 (-3.5A)
9CR  A 503 (-3.8A)
9CR  A 503 (-4.7A)
9CR  A 503 (-3.0A)
9CR  A 503 (-4.3A)
9CR  A 503 (-3.4A)
None
9CR  A 503 (-3.3A)
None
9CR  A 503 ( 4.8A)
 0.58A 6a5zL-5uanA:
34.4		 6a5zL-5uanA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6A60_D_9CRD501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xiu RXR-LIKE PROTEIN
(Biomphalaria
glabrata) 		12 / 12 ILE A 242
ALA A 245
ALA A 246
GLN A 249
LEU A 283
PHE A 287
ARG A 290
ALA A 301
ILE A 319
CYH A 406
HIS A 409
LEU A 410
 9CR  A 201 ( 4.4A)
9CR  A 201 (-3.6A)
9CR  A 201 (-3.6A)
9CR  A 201 (-4.1A)
9CR  A 201 ( 4.1A)
9CR  A 201 (-4.7A)
9CR  A 201 (-2.8A)
9CR  A 201 (-3.4A)
None
9CR  A 201 (-3.6A)
9CR  A 201 (-4.8A)
9CR  A 201 ( 4.8A)
 0.35A 6a60D-1xiuA:
32.3		 6a60D-1xiuA:
75.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6A60_D_9CRD501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xls RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		12 / 12 ILE A 268
ALA A 271
ALA A 272
GLN A 275
LEU A 309
PHE A 313
ARG A 316
ALA A 327
ILE A 345
CYH A 432
HIS A 435
LEU A 436
 9CR  A 801 (-3.9A)
9CR  A 801 (-3.6A)
9CR  A 801 (-3.5A)
9CR  A 801 (-4.7A)
9CR  A 801 (-4.2A)
9CR  A 801 (-4.3A)
9CR  A 801 (-2.6A)
9CR  A 801 (-3.3A)
9CR  A 801 ( 4.5A)
9CR  A 801 ( 3.7A)
None
9CR  A 801 (-4.7A)
 0.40A 6a60D-1xlsA:
35.0		 6a60D-1xlsA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6A60_D_9CRD501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		12 / 12 ILE A 268
ALA A 271
ALA A 272
GLN A 275
LEU A 309
PHE A 313
ARG A 316
ALA A 327
ILE A 345
CYH A 432
HIS A 435
LEU A 436
 9CR  A7223 (-3.9A)
9CR  A7223 (-3.5A)
9CR  A7223 (-4.2A)
9CR  A7223 (-4.6A)
9CR  A7223 ( 4.4A)
9CR  A7223 (-4.5A)
9CR  A7223 (-3.7A)
9CR  A7223 ( 4.7A)
9CR  A7223 ( 4.9A)
9CR  A7223 (-3.8A)
9CR  A7223 (-4.3A)
9CR  A7223 ( 4.7A)
 0.62A 6a60D-3dzuA:
34.4		 6a60D-3dzuA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6A60_D_9CRD501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5uan RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		7 / 12 ALA A 271
ALA A 272
GLN A 275
PHE A 313
ARG A 316
ALA A 327
ILE A 428
 9CR  A 503 (-3.5A)
9CR  A 503 (-3.5A)
9CR  A 503 (-3.8A)
9CR  A 503 (-4.7A)
9CR  A 503 (-3.0A)
9CR  A 503 (-3.4A)
None
 1.46A 6a60D-5uanA:
34.5		 6a60D-5uanA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6A60_D_9CRD501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5uan RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		11 / 12 ILE A 268
ALA A 271
ALA A 272
GLN A 275
LEU A 309
PHE A 313
ALA A 327
ILE A 345
CYH A 432
HIS A 435
LEU A 436
 9CR  A 503 (-4.0A)
9CR  A 503 (-3.5A)
9CR  A 503 (-3.5A)
9CR  A 503 (-3.8A)
9CR  A 503 (-3.7A)
9CR  A 503 (-4.7A)
9CR  A 503 (-3.4A)
None
9CR  A 503 (-3.3A)
None
9CR  A 503 ( 4.8A)
 0.59A 6a60D-5uanA:
34.5		 6a60D-5uanA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6A60_D_9CRD501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5uan RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		11 / 12 ILE A 268
ALA A 271
ALA A 272
GLN A 275
LEU A 309
PHE A 313
ARG A 316
ALA A 327
ILE A 345
CYH A 432
LEU A 436
 9CR  A 503 (-4.0A)
9CR  A 503 (-3.5A)
9CR  A 503 (-3.5A)
9CR  A 503 (-3.8A)
9CR  A 503 (-3.7A)
9CR  A 503 (-4.7A)
9CR  A 503 (-3.0A)
9CR  A 503 (-3.4A)
None
9CR  A 503 (-3.3A)
9CR  A 503 ( 4.8A)
 0.69A 6a60D-5uanA:
34.5		 6a60D-5uanA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CBZ_B_ESTB602_1
(ESTROGEN RECEPTOR)		 1xls RETINOIC ACID
RECEPTOR RXR-ALPHA
(Homo
sapiens) 		5 / 10 ALA A 272
LEU A 309
ARG A 316
ILE A 345
LEU A 436
 9CR  A 801 (-3.5A)
9CR  A 801 (-4.2A)
9CR  A 801 (-2.6A)
9CR  A 801 ( 4.5A)
9CR  A 801 (-4.7A)
 1.04A 6cbzB-1xlsA:
25.6		 6cbzB-1xlsA:
18.92