SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '9AF'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1L5R_A_RBFA859_1 (GLYCOGEN PHOSPHORYLASE, LIVER FORM)	5zbh	NEUROPEPTIDE Y RECEPTOR TYPE 1,T4 LYSOZYME,NEUROPEPTID E Y RECEPTOR TYPE 1 (Escherichia virus T4; Homo sapiens)	5 / 11	LEU A 279 ALA A 46 GLY A 48 TYR A 47 PHE A 302	9AF A1201 ( 3.9A) None None None 9AF A1201 (-3.6A)	1.43A	1l5rA-5zbhA: undetectable	1l5rA-5zbhA: 7.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RX7_A_FOLA161_0 (DIHYDROFOLATE REDUCTASE)	5zbh	NEUROPEPTIDE Y RECEPTOR TYPE 1,T4 LYSOZYME,NEUROPEPTID E Y RECEPTOR TYPE 1 (Homo sapiens; Escherichia virus T4)	6 / 12	ILE A 124 ASP A 86 PHE A 272 ILE A 227 LEU A 224 ILE A 128	9AF A1201 (-4.2A) None None None None None	1.50A	1rx7A-5zbhA: undetectable	1rx7A-5zbhA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PFJ_A_ADNA502_2 (ADENOSYLHOMOCYSTEINA SE)	5zbh	NEUROPEPTIDE Y RECEPTOR TYPE 1,T4 LYSOZYME,NEUROPEPTID E Y RECEPTOR TYPE 1 (Escherichia virus T4; Homo sapiens)	4 / 7	THR A 97 HIS A 306 LEU A 279 ASN A 283	None None 9AF A1201 ( 3.9A) 9AF A1201 (-3.7A)	1.11A	4pfjA-5zbhA: undetectable	4pfjA-5zbhA: 11.03

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1L5R_A_RBFA859_1","GLYCOGEN PHOSPHORYLASE, LIVER FORM","5zbh","NEUROPEPTIDE Y RECEPTOR TYPE 1,T4 LYSOZYME,NEUROPEPTIDE Y RECEPTOR TYPE 1","Escherichia virus T4;Homo sapiens",5,"LEU A 279;ALA A  46;GLY A  48;TYR A  47;PHE A 302","9AF A1201 ( 3.9A);None;None;None;9AF A1201 (-3.6A)","1.43A","1l5rA-5zbhA:undetectable",null],["1RX7_A_FOLA161_0","DIHYDROFOLATE REDUCTASE","5zbh","NEUROPEPTIDE Y RECEPTOR TYPE 1,T4 LYSOZYME,NEUROPEPTIDE Y RECEPTOR TYPE 1","Homo sapiens;Escherichia virus T4",6,"ILE A 124;ASP A  86;PHE A 272;ILE A 227;LEU A 224;ILE A 128","9AF A1201 (-4.2A);None;None;None;None;None","1.50A","1rx7A-5zbhA:undetectable","1l5rA-5zbhA:7.78"],["4PFJ_A_ADNA502_2","ADENOSYLHOMOCYSTEINASE","5zbh","NEUROPEPTIDE Y RECEPTOR TYPE 1,T4 LYSOZYME,NEUROPEPTIDE Y RECEPTOR TYPE 1","Escherichia virus T4;Homo sapiens",4,"THR A  97;HIS A 306;LEU A 279;ASN A 283","None;None;9AF A1201 ( 3.9A);9AF A1201 (-3.7A)","1.11A","4pfjA-5zbhA:undetectable","1rx7A-5zbhA:undetectable"]]