SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '98B'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2AKE_A_TRPA479_0 (TRYPTOPHANYL-TRNA SYNTHETASE)	4yjf	D-AMINO-ACID OXIDASE (Sus scrofa)	5 / 12	TYR B 224 GLY B 313 GLY B 315 THR B 317 ILE B 223	98B B 404 (-3.3A) FAD B 401 ( 3.5A) FAD B 401 (-3.2A) FAD B 401 (-3.7A) None	1.21A	2akeA-4yjfB: undetectable	2akeA-4yjfB: 20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2AZX_A_TRPA601_0 (TRYPTOPHANYL-TRNA SYNTHETASE)	4yjf	D-AMINO-ACID OXIDASE (Sus scrofa)	5 / 12	TYR B 224 GLY B 313 GLY B 315 THR B 317 ILE B 223	98B B 404 (-3.3A) FAD B 401 ( 3.5A) FAD B 401 (-3.2A) FAD B 401 (-3.7A) None	1.22A	2azxA-4yjfB: undetectable	2azxA-4yjfB: 19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2AZX_B_TRPB603_0 (TRYPTOPHANYL-TRNA SYNTHETASE)	4yjf	D-AMINO-ACID OXIDASE (Sus scrofa)	5 / 12	TYR B 224 GLY B 313 GLY B 315 THR B 317 ILE B 223	98B B 404 (-3.3A) FAD B 401 ( 3.5A) FAD B 401 (-3.2A) FAD B 401 (-3.7A) None	1.23A	2azxB-4yjfB: undetectable	2azxB-4yjfB: 19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2DR2_A_TRPA479_0 (TRYPTOPHANYL-TRNA SYNTHETASE)	4yjf	D-AMINO-ACID OXIDASE (Sus scrofa)	5 / 11	TYR B 224 GLY B 313 GLY B 315 THR B 317 ILE B 223	98B B 404 (-3.3A) FAD B 401 ( 3.5A) FAD B 401 (-3.2A) FAD B 401 (-3.7A) None	1.20A	2dr2A-4yjfB: 2.3	2dr2A-4yjfB: 20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4O7G_B_ASCB304_0 (PROBABLE TRANSMEMBRANE ASCORBATE FERRIREDUCTASE 2)	4yjf	D-AMINO-ACID OXIDASE (Sus scrofa)	4 / 6	HIS B 217 ILE B 215 TYR B 224 ASN B 134	None None 98B B 404 (-3.3A) None	1.49A	4o7gB-4yjfB: undetectable	4o7gB-4yjfB: 21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TZO_A_7V7A202_1 (ENDO-1,4-BETA-XYLANA SE A)	4yjf	D-AMINO-ACID OXIDASE (Sus scrofa)	5 / 12	PHE B 213 ALA B 48 TYR B 224 ALA B 49 GLY B 50	None FAD B 401 (-3.6A) 98B B 404 (-3.3A) FAD B 401 (-3.2A) FAD B 401 (-3.9A)	1.25A	5tzoA-4yjfB: undetectable	5tzoA-4yjfB: 20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TZO_B_7V7B201_1 (ENDO-1,4-BETA-XYLANA SE A)	4yjf	D-AMINO-ACID OXIDASE (Sus scrofa)	5 / 12	PHE B 213 ALA B 48 TYR B 224 ALA B 49 GLY B 50	None FAD B 401 (-3.6A) 98B B 404 (-3.3A) FAD B 401 (-3.2A) FAD B 401 (-3.9A)	1.15A	5tzoB-4yjfB: undetectable	5tzoB-4yjfB: 20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TZO_C_7V7C201_1 (ENDO-1,4-BETA-XYLANA SE A)	4yjf	D-AMINO-ACID OXIDASE (Sus scrofa)	5 / 12	PHE B 213 ALA B 48 TYR B 224 ALA B 49 GLY B 50	None FAD B 401 (-3.6A) 98B B 404 (-3.3A) FAD B 401 (-3.2A) FAD B 401 (-3.9A)	1.26A	5tzoC-4yjfB: undetectable	5tzoC-4yjfB: 20.12

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2AKE_A_TRPA479_0","TRYPTOPHANYL-TRNA SYNTHETASE","4yjf","D-AMINO-ACID OXIDASE","Sus scrofa",5,"TYR B 224;GLY B 313;GLY B 315;THR B 317;ILE B 223","98B B 404 (-3.3A);FAD B 401 ( 3.5A);FAD B 401 (-3.2A);FAD B 401 (-3.7A);None","1.21A","2akeA-4yjfB:undetectable",null],["2AZX_A_TRPA601_0","TRYPTOPHANYL-TRNA SYNTHETASE","4yjf","D-AMINO-ACID OXIDASE","Sus scrofa",5,"TYR B 224;GLY B 313;GLY B 315;THR B 317;ILE B 223","98B B 404 (-3.3A);FAD B 401 ( 3.5A);FAD B 401 (-3.2A);FAD B 401 (-3.7A);None","1.22A","2azxA-4yjfB:undetectable","2akeA-4yjfB:20.25"],["2AZX_B_TRPB603_0","TRYPTOPHANYL-TRNA SYNTHETASE","4yjf","D-AMINO-ACID OXIDASE","Sus scrofa",5,"TYR B 224;GLY B 313;GLY B 315;THR B 317;ILE B 223","98B B 404 (-3.3A);FAD B 401 ( 3.5A);FAD B 401 (-3.2A);FAD B 401 (-3.7A);None","1.23A","2azxB-4yjfB:undetectable","2azxA-4yjfB:19.79"],["2DR2_A_TRPA479_0","TRYPTOPHANYL-TRNA SYNTHETASE","4yjf","D-AMINO-ACID OXIDASE","Sus scrofa",5,"TYR B 224;GLY B 313;GLY B 315;THR B 317;ILE B 223","98B B 404 (-3.3A);FAD B 401 ( 3.5A);FAD B 401 (-3.2A);FAD B 401 (-3.7A);None","1.20A","2dr2A-4yjfB:2.3","2azxB-4yjfB:19.79"],["4O7G_B_ASCB304_0","PROBABLE TRANSMEMBRANE ASCORBATE FERRIREDUCTASE 2","4yjf","D-AMINO-ACID OXIDASE","Sus scrofa",4,"HIS B 217;ILE B 215;TYR B 224;ASN B 134","None;None;98B B 404 (-3.3A);None","1.49A","4o7gB-4yjfB:undetectable","2dr2A-4yjfB:20.25"],["5TZO_A_7V7A202_1","ENDO-1,4-BETA-XYLANASE A","4yjf","D-AMINO-ACID OXIDASE","Sus scrofa",5,"PHE B 213;ALA B  48;TYR B 224;ALA B  49;GLY B  50","None;FAD B 401 (-3.6A);98B B 404 (-3.3A);FAD B 401 (-3.2A);FAD B 401 (-3.9A)","1.25A","5tzoA-4yjfB:undetectable","4o7gB-4yjfB:21.43"],["5TZO_B_7V7B201_1","ENDO-1,4-BETA-XYLANASE A","4yjf","D-AMINO-ACID OXIDASE","Sus scrofa",5,"PHE B 213;ALA B  48;TYR B 224;ALA B  49;GLY B  50","None;FAD B 401 (-3.6A);98B B 404 (-3.3A);FAD B 401 (-3.2A);FAD B 401 (-3.9A)","1.15A","5tzoB-4yjfB:undetectable","5tzoA-4yjfB:20.12"],["5TZO_C_7V7C201_1","ENDO-1,4-BETA-XYLANASE A","4yjf","D-AMINO-ACID OXIDASE","Sus scrofa",5,"PHE B 213;ALA B  48;TYR B 224;ALA B  49;GLY B  50","None;FAD B 401 (-3.6A);98B B 404 (-3.3A);FAD B 401 (-3.2A);FAD B 401 (-3.9A)","1.26A","5tzoC-4yjfB:undetectable","5tzoB-4yjfB:20.12"]]