SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '93H'


List of Similar Pattern of Amino Acids


Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_A_DIFA1374_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)
5non S-NORCOCLAURINE
SYNTHASE

(Thalictrum
flavum)
4 / 5 TYR A 108
MET A 183
PRO A 179
LEU A  72
None
93H  A 501 (-3.4A)
93H  A 501 (-4.5A)
93H  A 501 (-4.3A)
1.25A 2wekA-5nonA:
undetectable
2wekA-5nonA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_B_DIFB1374_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)
5non S-NORCOCLAURINE
SYNTHASE

(Thalictrum
flavum)
4 / 6 TYR A 108
MET A 183
PRO A 179
LEU A  72
None
93H  A 501 (-3.4A)
93H  A 501 (-4.5A)
93H  A 501 (-4.3A)
1.24A 2wekB-5nonA:
undetectable
2wekB-5nonA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)
5non S-NORCOCLAURINE
SYNTHASE

(Thalictrum
flavum)
4 / 5 TYR A 108
MET A  97
THR A  98
LEU A  83
None
93H  A 501 (-4.2A)
None
None
1.33A 3ag2J-5nonA:
undetectable
3ag2J-5nonA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_J_CHDJ101_1
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5non S-NORCOCLAURINE
SYNTHASE

(Thalictrum
flavum)
4 / 5 TYR A 108
MET A  97
THR A  98
LEU A  83
None
93H  A 501 (-4.2A)
None
None
1.26A 5wauJ-5nonA:
undetectable
5wauJ-5nonA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5non S-NORCOCLAURINE
SYNTHASE

(Thalictrum
flavum)
4 / 5 TYR A 108
MET A  97
THR A  98
LEU A  83
None
93H  A 501 (-4.2A)
None
None
1.28A 5x19J-5nonA:
undetectable
5x19J-5nonA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5non S-NORCOCLAURINE
SYNTHASE

(Thalictrum
flavum)
4 / 5 TYR A 108
MET A  97
THR A  98
LEU A  83
None
93H  A 501 (-4.2A)
None
None
1.24A 5x1bJ-5nonA:
undetectable
5x1bJ-5nonA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5non S-NORCOCLAURINE
SYNTHASE

(Thalictrum
flavum)
4 / 5 TYR A 108
MET A  97
THR A  98
LEU A  83
None
93H  A 501 (-4.2A)
None
None
1.25A 5x1bW-5nonA:
undetectable
5x1bW-5nonA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5non S-NORCOCLAURINE
SYNTHASE

(Thalictrum
flavum)
4 / 5 TYR A 108
MET A  97
THR A  98
LEU A  83
None
93H  A 501 (-4.2A)
None
None
1.27A 5x1fW-5nonA:
undetectable
5x1fW-5nonA:
18.18