SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '90S'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DB1_A_VDXA428_2
(VITAMIN D NUCLEAR
RECEPTOR)		 5v9p LYSINE-SPECIFIC
DEMETHYLASE 5A
(Homo
sapiens) 		4 / 6 LEU A  80
TRP A 503
TYR A 504
VAL A 407
 None
90S  A 904 (-4.7A)
None
None
 1.11A 1db1A-5v9pA:
undetectable		 1db1A-5v9pA:
15.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RUA_H_BEZH601_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 5v9p LYSINE-SPECIFIC
DEMETHYLASE 5A
(Homo
sapiens) 		5 / 10 ALA A 581
TRP A 503
LEU A 495
GLY A 560
PHE A 562
 None
90S  A 904 (-4.7A)
None
None
None
 1.35A 1ruaH-5v9pA:
undetectable
1ruaL-5v9pA:
undetectable		 1ruaH-5v9pA:
15.25
1ruaL-5v9pA:
14.29