SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '8S0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HQA_A_ACRA705_2 (ALPHA-GLUCOSIDASE)	5yap	SCYLLO-INOSITOL DEHYDROGENASE WITH L-GLUCOSE DEHYDROGENASE ACTIVITY (Paracoccus laeviglucosivora ns)	4 / 8	ASN A 323 GLU A 165 HIS A 195 THR A 15	None 8S0 A 402 (-2.8A) 8S0 A 402 ( 3.9A) NAI A 401 (-4.0A)	1.36A	5hqaA-5yapA: undetectable	5hqaA-5yapA: 8.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X7P_B_ACRB1431_1 (GLYCOSIDE HYDROLASE FAMILY 31 ALPHA-GLUCOSIDASE)	5yap	SCYLLO-INOSITOL DEHYDROGENASE WITH L-GLUCOSE DEHYDROGENASE ACTIVITY (Paracoccus laeviglucosivora ns)	4 / 5	HIS A 88 ASP A 191 GLY A 190 ASN A 85	NAI A 401 (-3.8A) 8S0 A 402 (-4.3A) None NAI A 401 (-3.7A)	1.23A	5x7pB-5yapA: undetectable	5x7pB-5yapA: 5.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DJZ_A_GMJA301_0 (SIGMA NON-OPIOID INTRACELLULAR RECEPTOR 1)	5yap	SCYLLO-INOSITOL DEHYDROGENASE WITH L-GLUCOSE DEHYDROGENASE ACTIVITY (Paracoccus laeviglucosivora ns)	5 / 12	ILE A 357 PHE A 372 VAL A 210 LEU A 263 TYR A 135	None None None None 8S0 A 402 (-4.5A)	0.95A	6djzA-5yapA: undetectable	6djzA-5yapA: undetectable

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["5HQA_A_ACRA705_2","ALPHA-GLUCOSIDASE","5yap","SCYLLO-INOSITOL DEHYDROGENASE WITH L-GLUCOSE DEHYDROGENASE ACTIVITY","Paracoccus laeviglucosivorans",4,"ASN A 323;GLU A 165;HIS A 195;THR A  15","None;8S0 A 402 (-2.8A);8S0 A 402 ( 3.9A);NAI A 401 (-4.0A)","1.36A","5hqaA-5yapA:undetectable",null],["5X7P_B_ACRB1431_1","GLYCOSIDE HYDROLASE FAMILY 31 ALPHA-GLUCOSIDASE","5yap","SCYLLO-INOSITOL DEHYDROGENASE WITH L-GLUCOSE DEHYDROGENASE ACTIVITY","Paracoccus laeviglucosivorans",4,"HIS A  88;ASP A 191;GLY A 190;ASN A  85","NAI A 401 (-3.8A);8S0 A 402 (-4.3A);None;NAI A 401 (-3.7A)","1.23A","5x7pB-5yapA:undetectable","5hqaA-5yapA:8.14"],["6DJZ_A_GMJA301_0","SIGMA NON-OPIOID INTRACELLULAR RECEPTOR 1","5yap","SCYLLO-INOSITOL DEHYDROGENASE WITH L-GLUCOSE DEHYDROGENASE ACTIVITY","Paracoccus laeviglucosivorans",5,"ILE A 357;PHE A 372;VAL A 210;LEU A 263;TYR A 135","None;None;None;None;8S0 A 402 (-4.5A)","0.95A","6djzA-5yapA:undetectable","5x7pB-5yapA:5.36"]]