SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '8ND'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XIU_A_9CRA201_1
(RXR-LIKE PROTEIN)		 5uwa PROBABLE
PHOSPHOLIPID-BINDING
PROTEIN MLAC
(Escherichia
coli) 		5 / 12 ALA A 108
GLN A 107
LEU A 109
ALA A 110
VAL A  68
 8ND  A 301 ( 3.9A)
None
None
None
8ND  A 301 ( 4.6A)
 0.95A 1xiuA-5uwaA:
undetectable		 1xiuA-5uwaA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AY4_A_TPFA506_1
(CYP51, STEROL
14ALPHA-DEMETHYLASE)		 5uwa PROBABLE
PHOSPHOLIPID-BINDING
PROTEIN MLAC
(Escherichia
coli) 		5 / 10 MET A 166
PHE A 150
ALA A  35
THR A  38
LEU A 109
 8ND  A 301 ( 3.9A)
8ND  A 301 (-4.0A)
8ND  A 301 ( 4.2A)
8ND  A 301 ( 4.8A)
None
 1.40A 6ay4A-5uwaA:
2.0		 6ay4A-5uwaA:
18.46