SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '8M0'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VPT_A_SAMA400_0
(VP39)		 4f6t MOLYBDENUM STORAGE
PROTEIN SUBUNIT
ALPHA
MOLYBDENUM STORAGE
PROTEIN SUBUNIT BETA
(Azotobacter
vinelandii;
Azotobacter
vinelandii) 		5 / 12 GLY B  75
GLY B 172
HIS A 158
ALA B 111
LEU B 118
 None
None
8M0  B 302 (-3.7A)
None
None
 0.83A 1vptA-4f6tB:
undetectable		 1vptA-4f6tB:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VPT_A_SAMA400_0
(VP39)		 4f6t MOLYBDENUM STORAGE
PROTEIN SUBUNIT
ALPHA
MOLYBDENUM STORAGE
PROTEIN SUBUNIT BETA
(Azotobacter
vinelandii;
Azotobacter
vinelandii) 		5 / 12 ILE B  74
GLY B  75
GLY B 172
HIS A 158
LEU B 118
 None
None
None
8M0  B 302 (-3.7A)
None
 0.86A 1vptA-4f6tB:
undetectable		 1vptA-4f6tB:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_C_SAMC301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 4f6t MOLYBDENUM STORAGE
PROTEIN SUBUNIT
ALPHA
(Azotobacter
vinelandii) 		5 / 12 LEU A 116
GLY A  79
ASN A 112
ALA A 109
ALA A 106
 None
ATP  A 301 (-3.2A)
None
None
8M0  A 303 (-3.3A)
 1.13A 2bm9C-4f6tA:
undetectable		 2bm9C-4f6tA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OLS_A_ESTA600_1
(ESTROGEN RECEPTOR
BETA)		 4f6t MOLYBDENUM STORAGE
PROTEIN SUBUNIT BETA
(Azotobacter
vinelandii) 		5 / 12 LEU B 131
ALA B 129
LEU B 176
GLY B 181
LEU B  35
 None
8M0  B 302 (-3.1A)
8M0  B 302 (-4.2A)
None
None
 1.06A 3olsA-4f6tB:
undetectable		 3olsA-4f6tB:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FLC_C_RAPC999_1
(SERINE/THREONINE-PRO
TEIN KINASE MTOR
FKBP)		 4f6t MOLYBDENUM STORAGE
PROTEIN SUBUNIT BETA
(Azotobacter
vinelandii) 		4 / 8 GLU B 178
GLY B 130
THR B  76
PHE B 174
 None
8M0  B 302 (-3.8A)
None
None
 0.91A 5flcB-4f6tB:
undetectable		 5flcB-4f6tB:
12.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FLC_G_RAPG999_1
(SERINE/THREONINE-PRO
TEIN KINASE MTOR
FKBP)		 4f6t MOLYBDENUM STORAGE
PROTEIN SUBUNIT BETA
(Azotobacter
vinelandii) 		4 / 8 GLU B 178
GLY B 130
THR B  76
PHE B 174
 None
8M0  B 302 (-3.8A)
None
None
 0.91A 5flcF-4f6tB:
undetectable		 5flcF-4f6tB:
12.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZVG_B_SAMB401_0
(389AA LONG
HYPOTHETICAL
NUCLEOLAR PROTEIN)		 4f6t MOLYBDENUM STORAGE
PROTEIN SUBUNIT
ALPHA
(Azotobacter
vinelandii) 		5 / 12 PRO A 154
ALA A  84
ARG A  85
PRO A 166
PHE A  88
 8M0  A 303 (-4.4A)
None
ATP  A 301 (-4.2A)
None
None
 1.28A 5zvgB-4f6tA:
undetectable		 5zvgB-4f6tA:
22.72