SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '8K6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1S9P_C_DESC500_1 (ESTROGEN-RELATED RECEPTOR GAMMA)	5d91	AF2299 PROTEIN,PHOSPHATIDYL INOSITOL SYNTHASE (Archaeoglobus fulgidus; Renibacterium salmoninarum)	5 / 12	LEU A 174 LEU A 177 LEU A 180 ALA A 181 LEU A 125	8K6 A 337 ( 4.9A) None None None None	0.99A	1s9pC-5d91A: undetectable	1s9pC-5d91A: 19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2AOF_C_FRDC305_2 (POL POLYPROTEIN PEPTIDE INHIBITOR)	5d91	AF2299 PROTEIN,PHOSPHATIDYL INOSITOL SYNTHASE (Archaeoglobus fulgidus; Renibacterium salmoninarum)	4 / 5	LEU A 120 PRO A 113 ALA A 116 ILE A 117	None None None 8K6 A 305 ( 4.1A)	1.03A	2aofB-5d91A: undetectable	2aofB-5d91A: 14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PXM_B_ESTB2000_1 (ESTROGEN RECEPTOR)	5d91	AF2299 PROTEIN,PHOSPHATIDYL INOSITOL SYNTHASE (Archaeoglobus fulgidus; Renibacterium salmoninarum)	5 / 11	LEU A 90 LEU A 37 ILE A 59 GLY A 42 LEU A 44	None 8K6 A 334 ( 4.7A) None None 8K6 A 335 (-4.3A)	1.22A	4pxmB-5d91A: undetectable	4pxmB-5d91A: 22.87

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1S9P_C_DESC500_1","ESTROGEN-RELATED RECEPTOR GAMMA","5d91","AF2299 PROTEIN,PHOSPHATIDYLINOSITOL SYNTHASE","Archaeoglobus fulgidus;Renibacterium salmoninarum",5,"LEU A 174;LEU A 177;LEU A 180;ALA A 181;LEU A 125","8K6 A 337 ( 4.9A);None;None;None;None","0.99A","1s9pC-5d91A:undetectable",null],["2AOF_C_FRDC305_2","POL POLYPROTEIN;PEPTIDE INHIBITOR","5d91","AF2299 PROTEIN,PHOSPHATIDYLINOSITOL SYNTHASE","Archaeoglobus fulgidus;Renibacterium salmoninarum",4,"LEU A 120;PRO A 113;ALA A 116;ILE A 117","None;None;None;8K6 A 305 ( 4.1A)","1.03A","2aofB-5d91A:undetectable","1s9pC-5d91A:19.70"],["4PXM_B_ESTB2000_1","ESTROGEN RECEPTOR","5d91","AF2299 PROTEIN,PHOSPHATIDYLINOSITOL SYNTHASE","Archaeoglobus fulgidus;Renibacterium salmoninarum",5,"LEU A  90;LEU A  37;ILE A  59;GLY A  42;LEU A  44","None;8K6 A 334 ( 4.7A);None;None;8K6 A 335 (-4.3A)","1.22A","4pxmB-5d91A:undetectable","2aofB-5d91A:14.84"]]