SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '8ID'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BDW_B_DVAB8_0
(GRAMICIDIN A)		 4w6z ALCOHOL
DEHYDROGENASE 1
(Saccharomyces
cerevisiae) 		3 / 3 VAL A 295
VAL A 268
TRP A  92
 8ID  A 403 (-3.5A)
8ID  A 403 (-3.9A)
ETF  A 404 (-3.3A)
 0.98A 1bdwA-4w6zA:
undetectable
1bdwB-4w6zA:
undetectable		 1bdwA-4w6zA:
6.06
1bdwB-4w6zA:
6.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_D_URFD2021_1
(URIDINE
PHOSPHORYLASE)		 4w6z ALCOHOL
DEHYDROGENASE 1
(Saccharomyces
cerevisiae) 		4 / 7 GLY A 339
MET A 332
ILE A 317
PRO A 150
 None
8ID  A 403 ( 4.7A)
None
None
 1.08A 1rxcD-4w6zA:
undetectable		 1rxcD-4w6zA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T69_A_SHHA379_1
(HISTONE DEACETYLASE
8)		 4w6z ALCOHOL
DEHYDROGENASE 1
(Saccharomyces
cerevisiae) 		5 / 12 HIS A  66
GLY A  65
PHE A 125
MET A 332
TYR A 329
 ZN  A 401 ( 3.1A)
None
None
8ID  A 403 ( 4.7A)
None
 1.32A 1t69A-4w6zA:
2.5		 1t69A-4w6zA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_C_CHDC3525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 4w6z ALCOHOL
DEHYDROGENASE 1
(Saccharomyces
cerevisiae) 		4 / 7 HIS A  48
TRP A  54
TYR A 294
HIS A  44
 8ID  A 403 (-4.0A)
None
ETF  A 404 ( 4.5A)
8ID  A 403 (-3.5A)
 1.35A 1v54A-4w6zA:
undetectable
1v54C-4w6zA:
undetectable		 1v54A-4w6zA:
21.51
1v54C-4w6zA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_P_CHDP4525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 4w6z ALCOHOL
DEHYDROGENASE 1
(Saccharomyces
cerevisiae) 		4 / 7 HIS A  48
TRP A  54
TYR A 294
HIS A  44
 8ID  A 403 (-4.0A)
None
ETF  A 404 ( 4.5A)
8ID  A 403 (-3.5A)
 1.36A 1v54N-4w6zA:
undetectable
1v54P-4w6zA:
undetectable		 1v54N-4w6zA:
21.51
1v54P-4w6zA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_C_CHDC3525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 4w6z ALCOHOL
DEHYDROGENASE 1
(Saccharomyces
cerevisiae) 		4 / 7 HIS A  48
TRP A  54
TYR A 294
HIS A  44
 8ID  A 403 (-4.0A)
None
ETF  A 404 ( 4.5A)
8ID  A 403 (-3.5A)
 1.33A 1v55A-4w6zA:
undetectable
1v55C-4w6zA:
undetectable		 1v55A-4w6zA:
21.51
1v55C-4w6zA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4w6z ALCOHOL
DEHYDROGENASE 1
(Saccharomyces
cerevisiae) 		4 / 7 HIS A  48
TRP A  54
TYR A 294
HIS A  44
 8ID  A 403 (-4.0A)
None
ETF  A 404 ( 4.5A)
8ID  A 403 (-3.5A)
 1.34A 2dyrA-4w6zA:
undetectable
2dyrC-4w6zA:
undetectable		 2dyrA-4w6zA:
21.51
2dyrC-4w6zA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4w6z ALCOHOL
DEHYDROGENASE 1
(Saccharomyces
cerevisiae) 		4 / 7 HIS A  48
TRP A  54
TYR A 294
HIS A  44
 8ID  A 403 (-4.0A)
None
ETF  A 404 ( 4.5A)
8ID  A 403 (-3.5A)
 1.37A 2dyrN-4w6zA:
undetectable
2dyrP-4w6zA:
undetectable		 2dyrN-4w6zA:
21.51
2dyrP-4w6zA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4w6z ALCOHOL
DEHYDROGENASE 1
(Saccharomyces
cerevisiae) 		4 / 7 HIS A  48
TRP A  54
TYR A 294
HIS A  44
 8ID  A 403 (-4.0A)
None
ETF  A 404 ( 4.5A)
8ID  A 403 (-3.5A)
 1.34A 2eijA-4w6zA:
undetectable
2eijC-4w6zA:
undetectable		 2eijA-4w6zA:
21.51
2eijC-4w6zA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4w6z ALCOHOL
DEHYDROGENASE 1
(Saccharomyces
cerevisiae) 		4 / 7 HIS A  48
TRP A  54
TYR A 294
HIS A  44
 8ID  A 403 (-4.0A)
None
ETF  A 404 ( 4.5A)
8ID  A 403 (-3.5A)
 1.36A 2eijN-4w6zA:
undetectable
2eijP-4w6zA:
undetectable		 2eijN-4w6zA:
21.51
2eijP-4w6zA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4w6z ALCOHOL
DEHYDROGENASE 1
(Saccharomyces
cerevisiae) 		4 / 7 HIS A  48
TRP A  54
TYR A 294
HIS A  44
 8ID  A 403 (-4.0A)
None
ETF  A 404 ( 4.5A)
8ID  A 403 (-3.5A)
 1.35A 2eikA-4w6zA:
undetectable
2eikC-4w6zA:
undetectable		 2eikA-4w6zA:
21.51
2eikC-4w6zA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4w6z ALCOHOL
DEHYDROGENASE 1
(Saccharomyces
cerevisiae) 		4 / 7 HIS A  48
TRP A  54
TYR A 294
HIS A  44
 8ID  A 403 (-4.0A)
None
ETF  A 404 ( 4.5A)
8ID  A 403 (-3.5A)
 1.35A 2eilA-4w6zA:
undetectable
2eilC-4w6zA:
undetectable		 2eilA-4w6zA:
21.51
2eilC-4w6zA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4w6z ALCOHOL
DEHYDROGENASE 1
(Saccharomyces
cerevisiae) 		4 / 7 HIS A  48
TRP A  54
TYR A 294
HIS A  44
 8ID  A 403 (-4.0A)
None
ETF  A 404 ( 4.5A)
8ID  A 403 (-3.5A)
 1.38A 2eilN-4w6zA:
undetectable
2eilP-4w6zA:
undetectable		 2eilN-4w6zA:
21.51
2eilP-4w6zA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_A_CHDA1517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4w6z ALCOHOL
DEHYDROGENASE 1
(Saccharomyces
cerevisiae) 		4 / 7 HIS A  48
TRP A  54
TYR A 294
HIS A  44
 8ID  A 403 (-4.0A)
None
ETF  A 404 ( 4.5A)
8ID  A 403 (-3.5A)
 1.35A 2y69A-4w6zA:
undetectable
2y69C-4w6zA:
undetectable		 2y69A-4w6zA:
21.51
2y69C-4w6zA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4w6z ALCOHOL
DEHYDROGENASE 1
(Saccharomyces
cerevisiae) 		4 / 7 HIS A  48
TRP A  54
TYR A 294
HIS A  44
 8ID  A 403 (-4.0A)
None
ETF  A 404 ( 4.5A)
8ID  A 403 (-3.5A)
 1.36A 3abkA-4w6zA:
undetectable
3abkC-4w6zA:
undetectable		 3abkA-4w6zA:
21.51
3abkC-4w6zA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4w6z ALCOHOL
DEHYDROGENASE 1
(Saccharomyces
cerevisiae) 		4 / 7 HIS A  48
TRP A  54
TYR A 294
HIS A  44
 8ID  A 403 (-4.0A)
None
ETF  A 404 ( 4.5A)
8ID  A 403 (-3.5A)
 1.37A 3abkN-4w6zA:
undetectable
3abkP-4w6zA:
undetectable		 3abkN-4w6zA:
21.51
3abkP-4w6zA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4w6z ALCOHOL
DEHYDROGENASE 1
(Saccharomyces
cerevisiae) 		4 / 7 HIS A  48
TRP A  54
TYR A 294
HIS A  44
 8ID  A 403 (-4.0A)
None
ETF  A 404 ( 4.5A)
8ID  A 403 (-3.5A)
 1.33A 3abmN-4w6zA:
undetectable
3abmP-4w6zA:
undetectable		 3abmN-4w6zA:
21.51
3abmP-4w6zA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4w6z ALCOHOL
DEHYDROGENASE 1
(Saccharomyces
cerevisiae) 		4 / 7 HIS A  48
TRP A  54
TYR A 294
HIS A  44
 8ID  A 403 (-4.0A)
None
ETF  A 404 ( 4.5A)
8ID  A 403 (-3.5A)
 1.37A 3ag2N-4w6zA:
undetectable
3ag2P-4w6zA:
undetectable		 3ag2N-4w6zA:
21.51
3ag2P-4w6zA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4w6z ALCOHOL
DEHYDROGENASE 1
(Saccharomyces
cerevisiae) 		4 / 7 HIS A  48
TRP A  54
TYR A 294
HIS A  44
 8ID  A 403 (-4.0A)
None
ETF  A 404 ( 4.5A)
8ID  A 403 (-3.5A)
 1.36A 3ag3A-4w6zA:
undetectable
3ag3C-4w6zA:
undetectable		 3ag3A-4w6zA:
21.51
3ag3C-4w6zA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4w6z ALCOHOL
DEHYDROGENASE 1
(Saccharomyces
cerevisiae) 		4 / 7 HIS A  48
TRP A  54
TYR A 294
HIS A  44
 8ID  A 403 (-4.0A)
None
ETF  A 404 ( 4.5A)
8ID  A 403 (-3.5A)
 1.34A 3ag3N-4w6zA:
undetectable
3ag3P-4w6zA:
undetectable		 3ag3N-4w6zA:
21.51
3ag3P-4w6zA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4w6z ALCOHOL
DEHYDROGENASE 1
(Saccharomyces
cerevisiae) 		4 / 7 HIS A  48
TRP A  54
TYR A 294
HIS A  44
 8ID  A 403 (-4.0A)
None
ETF  A 404 ( 4.5A)
8ID  A 403 (-3.5A)
 1.34A 3ag4A-4w6zA:
undetectable
3ag4C-4w6zA:
undetectable		 3ag4A-4w6zA:
21.51
3ag4C-4w6zA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4w6z ALCOHOL
DEHYDROGENASE 1
(Saccharomyces
cerevisiae) 		4 / 7 HIS A  48
TRP A  54
TYR A 294
HIS A  44
 8ID  A 403 (-4.0A)
None
ETF  A 404 ( 4.5A)
8ID  A 403 (-3.5A)
 1.38A 3ag4N-4w6zA:
undetectable
3ag4P-4w6zA:
undetectable		 3ag4N-4w6zA:
21.51
3ag4P-4w6zA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCB_A_017A201_1
(PROTEASE)		 4w6z ALCOHOL
DEHYDROGENASE 1
(Saccharomyces
cerevisiae) 		5 / 12 GLY A 177
ALA A 178
ILE A 213
GLY A 339
VAL A 187
 8ID  A 403 (-3.3A)
None
None
None
None
 1.03A 3ucbA-4w6zA:
undetectable		 3ucbA-4w6zA:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_A_AERA601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 4w6z ALCOHOL
DEHYDROGENASE 1
(Saccharomyces
cerevisiae) 		4 / 5 TYR A 294
LEU A 182
ASP A  46
VAL A 148
 ETF  A 404 ( 4.5A)
8ID  A 403 (-3.3A)
None
None
 1.30A 4nkvA-4w6zA:
undetectable		 4nkvA-4w6zA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_B_SAMB601_0
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 4w6z ALCOHOL
DEHYDROGENASE 1
(Saccharomyces
cerevisiae) 		5 / 12 ALA A 179
GLY A 180
GLY A 339
GLY A 199
PHE A 218
 8ID  A 403 (-4.2A)
8ID  A 403 (-3.0A)
None
None
None
 1.00A 4obwB-4w6zA:
5.1		 4obwB-4w6zA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA2_A_SHHA404_1
(HISTONE DEACETYLASE
8)		 4w6z ALCOHOL
DEHYDROGENASE 1
(Saccharomyces
cerevisiae) 		5 / 12 HIS A  66
GLY A  65
PHE A 125
MET A 332
TYR A 329
 ZN  A 401 ( 3.1A)
None
None
8ID  A 403 ( 4.7A)
None
 1.31A 4qa2A-4w6zA:
undetectable		 4qa2A-4w6zA:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA2_B_SHHB404_1
(HISTONE DEACETYLASE
8)		 4w6z ALCOHOL
DEHYDROGENASE 1
(Saccharomyces
cerevisiae) 		5 / 12 HIS A  66
GLY A  65
PHE A 125
MET A 332
TYR A 329
 ZN  A 401 ( 3.1A)
None
None
8ID  A 403 ( 4.7A)
None
 1.26A 4qa2B-4w6zA:
3.1		 4qa2B-4w6zA:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A5Z_C_WJZC304_0
(BETA-LACTAMASE NDM-1)		 4w6z ALCOHOL
DEHYDROGENASE 1
(Saccharomyces
cerevisiae) 		4 / 7 MET A 332
HIS A  66
CYH A 153
GLY A  41
 8ID  A 403 ( 4.7A)
ZN  A 401 ( 3.1A)
ZN  A 401 (-2.3A)
None
 1.13A 5a5zC-4w6zA:
2.0		 5a5zC-4w6zA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4w6z ALCOHOL
DEHYDROGENASE 1
(Saccharomyces
cerevisiae) 		4 / 7 HIS A  48
TRP A  54
TYR A 294
HIS A  44
 8ID  A 403 (-4.0A)
None
ETF  A 404 ( 4.5A)
8ID  A 403 (-3.5A)
 1.35A 5b1aN-4w6zA:
undetectable
5b1aP-4w6zA:
undetectable		 5b1aN-4w6zA:
21.51
5b1aP-4w6zA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4w6z ALCOHOL
DEHYDROGENASE 1
(Saccharomyces
cerevisiae) 		4 / 7 HIS A  48
TRP A  54
TYR A 294
HIS A  44
 8ID  A 403 (-4.0A)
None
ETF  A 404 ( 4.5A)
8ID  A 403 (-3.5A)
 1.34A 5b1bN-4w6zA:
undetectable
5b1bP-4w6zA:
undetectable		 5b1bN-4w6zA:
21.51
5b1bP-4w6zA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4w6z ALCOHOL
DEHYDROGENASE 1
(Saccharomyces
cerevisiae) 		4 / 7 HIS A  48
TRP A  54
TYR A 294
HIS A  44
 8ID  A 403 (-4.0A)
None
ETF  A 404 ( 4.5A)
8ID  A 403 (-3.5A)
 1.34A 5b3sN-4w6zA:
undetectable
5b3sP-4w6zA:
undetectable		 5b3sN-4w6zA:
21.51
5b3sP-4w6zA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FSA_B_X2NB590_2
(CYP51 VARIANT1)		 4w6z ALCOHOL
DEHYDROGENASE 1
(Saccharomyces
cerevisiae) 		3 / 3 PRO A 271
LEU A 182
SER A 248
 None
8ID  A 403 (-3.3A)
8ID  A 403 (-3.5A)
 0.78A 5fsaB-4w6zA:
undetectable		 5fsaB-4w6zA:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4w6z ALCOHOL
DEHYDROGENASE 1
(Saccharomyces
cerevisiae) 		4 / 7 HIS A  48
TRP A  54
TYR A 294
HIS A  44
 8ID  A 403 (-4.0A)
None
ETF  A 404 ( 4.5A)
8ID  A 403 (-3.5A)
 1.30A 5iy5A-4w6zA:
undetectable
5iy5C-4w6zA:
undetectable		 5iy5A-4w6zA:
21.51
5iy5C-4w6zA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MFX_A_ACTA701_0
(GENOME POLYPROTEIN)		 4w6z ALCOHOL
DEHYDROGENASE 1
(Saccharomyces
cerevisiae) 		4 / 5 THR A  45
HIS A  48
ALA A  49
ASP A  46
 ETF  A 404 (-2.6A)
8ID  A 403 (-4.0A)
None
None
 1.30A 5mfxA-4w6zA:
undetectable		 5mfxA-4w6zA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NCD_D_ACTD301_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 4w6z ALCOHOL
DEHYDROGENASE 1
(Saccharomyces
cerevisiae) 		4 / 4 ASP A  53
HIS A  48
HIS A  44
HIS A  51
 None
8ID  A 403 (-4.0A)
8ID  A 403 (-3.5A)
None
 1.38A 5ncdD-4w6zA:
undetectable		 5ncdD-4w6zA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_A_SAMA601_0
(NS5
METHYLTRANSFERASE)		 4w6z ALCOHOL
DEHYDROGENASE 1
(Saccharomyces
cerevisiae) 		5 / 12 GLY A 339
GLY A 155
GLY A 180
THR A 157
ILE A 151
 None
None
8ID  A 403 (-3.0A)
8ID  A 403 (-2.9A)
None
 1.01A 5wz1A-4w6zA:
4.1		 5wz1A-4w6zA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_C_SAMC601_0
(NS5
METHYLTRANSFERASE)		 4w6z ALCOHOL
DEHYDROGENASE 1
(Saccharomyces
cerevisiae) 		5 / 12 GLY A 339
GLY A 155
GLY A 180
THR A 157
ILE A 151
 None
None
8ID  A 403 (-3.0A)
8ID  A 403 (-2.9A)
None
 1.03A 5wz1C-4w6zA:
4.1		 5wz1C-4w6zA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_D_SAMD601_0
(NS5
METHYLTRANSFERASE)		 4w6z ALCOHOL
DEHYDROGENASE 1
(Saccharomyces
cerevisiae) 		5 / 12 GLY A 339
GLY A 155
GLY A 180
THR A 157
ILE A 151
 None
None
8ID  A 403 (-3.0A)
8ID  A 403 (-2.9A)
None
 1.01A 5wz1D-4w6zA:
4.0		 5wz1D-4w6zA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_E_SAME601_0
(NS5
METHYLTRANSFERASE)		 4w6z ALCOHOL
DEHYDROGENASE 1
(Saccharomyces
cerevisiae) 		5 / 12 GLY A 339
GLY A 155
GLY A 180
THR A 157
ILE A 151
 None
None
8ID  A 403 (-3.0A)
8ID  A 403 (-2.9A)
None
 1.03A 5wz1E-4w6zA:
4.0		 5wz1E-4w6zA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_F_SAMF601_0
(NS5
METHYLTRANSFERASE)		 4w6z ALCOHOL
DEHYDROGENASE 1
(Saccharomyces
cerevisiae) 		5 / 12 GLY A 339
GLY A 155
GLY A 180
THR A 157
ILE A 151
 None
None
8ID  A 403 (-3.0A)
8ID  A 403 (-2.9A)
None
 1.01A 5wz1F-4w6zA:
4.2		 5wz1F-4w6zA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_G_SAMG601_0
(NS5
METHYLTRANSFERASE)		 4w6z ALCOHOL
DEHYDROGENASE 1
(Saccharomyces
cerevisiae) 		5 / 12 GLY A 339
GLY A 155
GLY A 180
THR A 157
ILE A 151
 None
None
8ID  A 403 (-3.0A)
8ID  A 403 (-2.9A)
None
 1.02A 5wz1G-4w6zA:
4.1		 5wz1G-4w6zA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4w6z ALCOHOL
DEHYDROGENASE 1
(Saccharomyces
cerevisiae) 		4 / 7 HIS A  48
TRP A  54
TYR A 294
HIS A  44
 8ID  A 403 (-4.0A)
None
ETF  A 404 ( 4.5A)
8ID  A 403 (-3.5A)
 1.31A 5x1fN-4w6zA:
undetectable
5x1fP-4w6zA:
undetectable		 5x1fN-4w6zA:
21.51
5x1fP-4w6zA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4w6z ALCOHOL
DEHYDROGENASE 1
(Saccharomyces
cerevisiae) 		4 / 7 HIS A  48
TRP A  54
TYR A 294
HIS A  44
 8ID  A 403 (-4.0A)
None
ETF  A 404 ( 4.5A)
8ID  A 403 (-3.5A)
 1.34A 5zcqN-4w6zA:
undetectable
5zcqP-4w6zA:
undetectable		 5zcqN-4w6zA:
21.51
5zcqP-4w6zA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4w6z ALCOHOL
DEHYDROGENASE 1
(Saccharomyces
cerevisiae) 		4 / 7 HIS A  48
TRP A  54
TYR A 294
HIS A  44
 8ID  A 403 (-4.0A)
None
ETF  A 404 ( 4.5A)
8ID  A 403 (-3.5A)
 1.37A 6nmfN-4w6zA:
undetectable
6nmfP-4w6zA:
undetectable		 6nmfN-4w6zA:
21.51
6nmfP-4w6zA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_P_CHDP302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4w6z ALCOHOL
DEHYDROGENASE 1
(Saccharomyces
cerevisiae) 		4 / 7 HIS A  48
TRP A  54
TYR A 294
HIS A  44
 8ID  A 403 (-4.0A)
None
ETF  A 404 ( 4.5A)
8ID  A 403 (-3.5A)
 1.37A 6nmpN-4w6zA:
undetectable
6nmpP-4w6zA:
undetectable		 6nmpN-4w6zA:
21.51
6nmpP-4w6zA:
19.60