SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '8H6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3L8L_B_DVAB6_0 (GRAMICIDIN D)	5xww	AMPHB (Streptomyces nodosus)	3 / 3	TRP A 359 ALA A 368 VAL A 358	8H6 A 502 (-4.1A) None None	0.96A	3l8lA-5xwwA: undetectable 3l8lB-5xwwA: undetectable	3l8lA-5xwwA: undetectable 3l8lB-5xwwA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LBD_A_9CRA424_1 (RETINOIC ACID RECEPTOR GAMMA)	5xww	AMPHB (Streptomyces nodosus)	5 / 12	ALA A 309 LEU A 326 MET A 327 ARG A 251 ALA A 357	8H6 A 502 ( 4.5A) None None NAP A 501 (-3.6A) None	1.44A	3lbdA-5xwwA: undetectable	3lbdA-5xwwA: 22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UBO_B_ADNB353_2 (ADENOSINE KINASE)	5xww	AMPHB (Streptomyces nodosus)	4 / 5	SER A 354 ILE A 230 TYR A 367 GLY A 394	8H6 A 502 ( 3.2A) NAP A 501 (-3.9A) NAP A 501 ( 4.5A) NAP A 501 (-4.9A)	0.92A	3uboB-5xwwA: 4.8	3uboB-5xwwA: 11.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UIL_H_QI9H1223_0 (FAB 314.1)	5xww	AMPHB (Streptomyces nodosus)	5 / 12	ALA A 316 GLU A 153 GLY A 362 GLY A 147 LEU A 104	None None 8H6 A 502 (-3.1A) None None	1.05A	4uilH-5xwwA: undetectable 4uilL-5xwwA: undetectable	4uilH-5xwwA: undetectable 4uilL-5xwwA: undetectable

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3L8L_B_DVAB6_0","GRAMICIDIN D","5xww","AMPHB","Streptomyces nodosus",3,"TRP A 359;ALA A 368;VAL A 358","8H6 A 502 (-4.1A);None;None","0.96A","3l8lA-5xwwA:undetectable;3l8lB-5xwwA:undetectable",null],["3LBD_A_9CRA424_1","RETINOIC ACID RECEPTOR GAMMA","5xww","AMPHB","Streptomyces nodosus",5,"ALA A 309;LEU A 326;MET A 327;ARG A 251;ALA A 357","8H6 A 502 ( 4.5A);None;None;NAP A 501 (-3.6A);None","1.44A","3lbdA-5xwwA:undetectable","3l8lA-5xwwA:undetectable;3l8lB-5xwwA:undetectable"],["3UBO_B_ADNB353_2","ADENOSINE KINASE","5xww","AMPHB","Streptomyces nodosus",4,"SER A 354;ILE A 230;TYR A 367;GLY A 394","8H6 A 502 ( 3.2A);NAP A 501 (-3.9A);NAP A 501 ( 4.5A);NAP A 501 (-4.9A)","0.92A","3uboB-5xwwA:4.8","3lbdA-5xwwA:22.08"],["4UIL_H_QI9H1223_0","FAB 314.1","5xww","AMPHB","Streptomyces nodosus",5,"ALA A 316;GLU A 153;GLY A 362;GLY A 147;LEU A 104","None;None;8H6 A 502 (-3.1A);None;None","1.05A","4uilH-5xwwA:undetectable;4uilL-5xwwA:undetectable","3uboB-5xwwA:11.01"]]