SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '8H6'
DrReposER ID / Desc. | Hit PDBID |
Hit Macromolecule |
Res. Matches |
Interface | HETATM | RMSD | Dali Z-score |
Seq. Identity (%) |
View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3L8L_B_DVAB6_0 (GRAMICIDIN D) |
5xww | AMPHB (Streptomycesnodosus) | 3 / 3 | TRP A 359ALA A 368VAL A 358 | 8H6 A 502 (-4.1A)NoneNone | 0.96A | 3l8lA-5xwwA:undetectable3l8lB-5xwwA:undetectable | 3l8lA-5xwwA:undetectable3l8lB-5xwwA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3LBD_A_9CRA424_1 (RETINOIC ACIDRECEPTOR GAMMA) |
5xww | AMPHB (Streptomycesnodosus) | 5 / 12 | ALA A 309LEU A 326MET A 327ARG A 251ALA A 357 | 8H6 A 502 ( 4.5A)NoneNoneNAP A 501 (-3.6A)None | 1.44A | 3lbdA-5xwwA:undetectable | 3lbdA-5xwwA:22.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3UBO_B_ADNB353_2 (ADENOSINE KINASE) |
5xww | AMPHB (Streptomycesnodosus) | 4 / 5 | SER A 354ILE A 230TYR A 367GLY A 394 | 8H6 A 502 ( 3.2A)NAP A 501 (-3.9A)NAP A 501 ( 4.5A)NAP A 501 (-4.9A) | 0.92A | 3uboB-5xwwA:4.8 | 3uboB-5xwwA:11.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4UIL_H_QI9H1223_0 (FAB 314.1) |
5xww | AMPHB (Streptomycesnodosus) | 5 / 12 | ALA A 316GLU A 153GLY A 362GLY A 147LEU A 104 | NoneNone8H6 A 502 (-3.1A)NoneNone | 1.05A | 4uilH-5xwwA:undetectable4uilL-5xwwA:undetectable | 4uilH-5xwwA:undetectable4uilL-5xwwA:undetectable |