SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '8ES'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DCF_A_ACAA501_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 5ung CHIMERA PROTEIN OF
TYPE-2 ANGIOTENSIN
II RECEPTOR AND
SOLUBLE CYTOCHROME
B562
(Escherichia
coli;
Homo
sapiens) 		4 / 6 ALA B 194
TYR B 103
TRP B 110
ILE B 196
 None
8ES  B1201 (-4.8A)
None
None
 1.21A 2dcfA-5ungB:
undetectable		 2dcfA-5ungB:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O01_A_PQNA5001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 5ung CHIMERA PROTEIN OF
TYPE-2 ANGIOTENSIN
II RECEPTOR AND
SOLUBLE CYTOCHROME
B562
(Escherichia
coli;
Homo
sapiens) 		4 / 8 PHE B 308
SER B 311
ALA B  95
LEU B  97
 8ES  B1201 (-3.7A)
None
None
None
 0.87A 2o01A-5ungB:
undetectable		 2o01A-5ungB:
19.76