SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '8D3'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_A_PNXA1435_1
(CHITINASE)		 5xra CANNABINOID RECEPTOR
1,FLAVODOXIN,CANNABI
NOID RECEPTOR 1
(Desulfovibrio
vulgaris;
Homo
sapiens) 		4 / 6 TRP A 356
GLY A 166
PHE A 170
SER A 167
 None
None
8D3  A 602 ( 4.4A)
None
 1.24A 2a3cA-5xraA:
undetectable		 2a3cA-5xraA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_B_PNXB2434_1
(CHITINASE)		 5xra CANNABINOID RECEPTOR
1,FLAVODOXIN,CANNABI
NOID RECEPTOR 1
(Desulfovibrio
vulgaris;
Homo
sapiens) 		4 / 6 TRP A 356
GLY A 166
PHE A 170
SER A 167
 None
None
8D3  A 602 ( 4.4A)
None
 1.32A 2a3cB-5xraA:
undetectable		 2a3cB-5xraA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9K_B_CAMB424_0
(CYTOCHROME P450)		 5xra CANNABINOID RECEPTOR
1,FLAVODOXIN,CANNABI
NOID RECEPTOR 1
(Desulfovibrio
vulgaris;
Homo
sapiens) 		5 / 9 TRP A 279
LEU A 359
LEU A 360
GLY A 357
VAL A 204
 8D3  A 602 ( 3.5A)
8D3  A 602 ( 4.5A)
None
None
None
 1.29A 4c9kB-5xraA:
undetectable		 4c9kB-5xraA:
22.00