SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '89F'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_A_Y00A601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 5v54 5-HYDROXYTRYPTAMINE
RECEPTOR 1B,OB-1
FUSED 5-HT1B
RECEPTOR,5-HYDROXYTR
YPTAMINE RECEPTOR 1B
(Homo
sapiens;
Spodoptera
frugiperda) 		6 / 12 TRP A 125
ASP A 129
SER A 212
PHE A 330
PHE A 331
TYR A 359
 None
89F  A1201 (-3.3A)
89F  A1201 ( 3.8A)
89F  A1201 (-4.1A)
89F  A1201 (-4.6A)
None
 0.79A 2y00A-5v54A:
28.8		 2y00A-5v54A:
14.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_B_Y00B601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 5v54 5-HYDROXYTRYPTAMINE
RECEPTOR 1B,OB-1
FUSED 5-HT1B
RECEPTOR,5-HYDROXYTR
YPTAMINE RECEPTOR 1B
(Homo
sapiens;
Spodoptera
frugiperda) 		6 / 12 TRP A 125
ASP A 129
SER A 212
PHE A 330
PHE A 331
TYR A 359
 None
89F  A1201 (-3.3A)
89F  A1201 ( 3.8A)
89F  A1201 (-4.1A)
89F  A1201 (-4.6A)
None
 0.82A 2y00B-5v54A:
28.5		 2y00B-5v54A:
14.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_B_Y00B601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 5v54 5-HYDROXYTRYPTAMINE
RECEPTOR 1B,OB-1
FUSED 5-HT1B
RECEPTOR,5-HYDROXYTR
YPTAMINE RECEPTOR 1B
(Homo
sapiens;
Spodoptera
frugiperda) 		5 / 12 TRP A 125
ASP A 129
SER A 212
PHE A 330
TYR A 359
 None
89F  A1201 (-3.3A)
89F  A1201 ( 3.8A)
89F  A1201 (-4.1A)
None
 1.30A 2y00B-5v54A:
28.5		 2y00B-5v54A:
14.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y01_A_Y00A601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 5v54 5-HYDROXYTRYPTAMINE
RECEPTOR 1B,OB-1
FUSED 5-HT1B
RECEPTOR,5-HYDROXYTR
YPTAMINE RECEPTOR 1B
(Homo
sapiens;
Spodoptera
frugiperda) 		7 / 12 TRP A 125
ASP A 129
SER A 212
PHE A 330
PHE A 331
TRP A 356
TYR A 359
 None
89F  A1201 (-3.3A)
89F  A1201 ( 3.8A)
89F  A1201 (-4.1A)
89F  A1201 (-4.6A)
None
None
 0.94A 2y01A-5v54A:
28.7		 2y01A-5v54A:
14.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y01_B_Y00B601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 5v54 5-HYDROXYTRYPTAMINE
RECEPTOR 1B,OB-1
FUSED 5-HT1B
RECEPTOR,5-HYDROXYTR
YPTAMINE RECEPTOR 1B
(Homo
sapiens;
Spodoptera
frugiperda) 		6 / 12 TRP A 125
ASP A 129
SER A 212
PHE A 330
PHE A 331
TYR A 359
 None
89F  A1201 (-3.3A)
89F  A1201 ( 3.8A)
89F  A1201 (-4.1A)
89F  A1201 (-4.6A)
None
 0.81A 2y01B-5v54A:
28.4		 2y01B-5v54A:
14.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y01_B_Y00B601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 5v54 5-HYDROXYTRYPTAMINE
RECEPTOR 1B,OB-1
FUSED 5-HT1B
RECEPTOR,5-HYDROXYTR
YPTAMINE RECEPTOR 1B
(Homo
sapiens;
Spodoptera
frugiperda) 		5 / 12 TRP A 125
ASP A 129
SER A 212
PHE A 330
TYR A 359
 None
89F  A1201 (-3.3A)
89F  A1201 ( 3.8A)
89F  A1201 (-4.1A)
None
 1.25A 2y01B-5v54A:
28.4		 2y01B-5v54A:
14.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y03_A_5FWA601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 5v54 5-HYDROXYTRYPTAMINE
RECEPTOR 1B,OB-1
FUSED 5-HT1B
RECEPTOR,5-HYDROXYTR
YPTAMINE RECEPTOR 1B
(Homo
sapiens;
Spodoptera
frugiperda) 		6 / 12 TRP A 125
ASP A 129
SER A 212
PHE A 330
PHE A 331
TYR A 359
 None
89F  A1201 (-3.3A)
89F  A1201 ( 3.8A)
89F  A1201 (-4.1A)
89F  A1201 (-4.6A)
None
 0.76A 2y03A-5v54A:
28.6		 2y03A-5v54A:
14.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y03_B_5FWB601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 5v54 5-HYDROXYTRYPTAMINE
RECEPTOR 1B,OB-1
FUSED 5-HT1B
RECEPTOR,5-HYDROXYTR
YPTAMINE RECEPTOR 1B
(Homo
sapiens;
Spodoptera
frugiperda) 		6 / 12 TRP A 125
ASP A 129
SER A 212
PHE A 330
PHE A 331
TYR A 359
 None
89F  A1201 (-3.3A)
89F  A1201 ( 3.8A)
89F  A1201 (-4.1A)
89F  A1201 (-4.6A)
None
 0.77A 2y03B-5v54A:
28.5		 2y03B-5v54A:
14.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y04_A_68HA601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 5v54 5-HYDROXYTRYPTAMINE
RECEPTOR 1B,OB-1
FUSED 5-HT1B
RECEPTOR,5-HYDROXYTR
YPTAMINE RECEPTOR 1B
(Homo
sapiens;
Spodoptera
frugiperda) 		6 / 11 TRP A 125
ASP A 129
SER A 212
PHE A 330
PHE A 331
TYR A 359
 None
89F  A1201 (-3.3A)
89F  A1201 ( 3.8A)
89F  A1201 (-4.1A)
89F  A1201 (-4.6A)
None
 1.26A 2y04A-5v54A:
28.5		 2y04A-5v54A:
14.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y04_A_68HA601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 5v54 5-HYDROXYTRYPTAMINE
RECEPTOR 1B,OB-1
FUSED 5-HT1B
RECEPTOR,5-HYDROXYTR
YPTAMINE RECEPTOR 1B
(Homo
sapiens;
Spodoptera
frugiperda) 		5 / 11 TRP A 125
SER A 212
PHE A 330
PHE A 331
TYR A 359
 None
89F  A1201 ( 3.8A)
89F  A1201 (-4.1A)
89F  A1201 (-4.6A)
None
 0.91A 2y04A-5v54A:
28.5		 2y04A-5v54A:
14.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y04_B_68HB601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 5v54 5-HYDROXYTRYPTAMINE
RECEPTOR 1B,OB-1
FUSED 5-HT1B
RECEPTOR,5-HYDROXYTR
YPTAMINE RECEPTOR 1B
(Homo
sapiens;
Spodoptera
frugiperda) 		6 / 12 TRP A 125
ASP A 129
SER A 212
PHE A 330
PHE A 331
TYR A 359
 None
89F  A1201 (-3.3A)
89F  A1201 ( 3.8A)
89F  A1201 (-4.1A)
89F  A1201 (-4.6A)
None
 1.25A 2y04B-5v54A:
28.4		 2y04B-5v54A:
14.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y04_B_68HB601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 5v54 5-HYDROXYTRYPTAMINE
RECEPTOR 1B,OB-1
FUSED 5-HT1B
RECEPTOR,5-HYDROXYTR
YPTAMINE RECEPTOR 1B
(Homo
sapiens;
Spodoptera
frugiperda) 		5 / 12 TRP A 125
SER A 212
PHE A 330
PHE A 331
TYR A 359
 None
89F  A1201 ( 3.8A)
89F  A1201 (-4.1A)
89F  A1201 (-4.6A)
None
 0.84A 2y04B-5v54A:
28.4		 2y04B-5v54A:
14.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D4S_A_TIMA401_1
(BETA-2 ADRENERGIC
RECEPTOR/T4-LYSOZYME
CHIMERA)		 5v54 5-HYDROXYTRYPTAMINE
RECEPTOR 1B,OB-1
FUSED 5-HT1B
RECEPTOR,5-HYDROXYTR
YPTAMINE RECEPTOR 1B
(Homo
sapiens;
Spodoptera
frugiperda) 		6 / 12 TRP A 125
ASP A 129
SER A 212
TRP A 327
PHE A 331
TYR A 359
 None
89F  A1201 (-3.3A)
89F  A1201 ( 3.8A)
89F  A1201 (-3.6A)
89F  A1201 (-4.6A)
None
 0.78A 3d4sA-5v54A:
28.0		 3d4sA-5v54A:
11.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NYA_A_JTZA1203_1
(BETA-2 ADRENERGIC
RECEPTOR, LYSOZYME)		 5v54 5-HYDROXYTRYPTAMINE
RECEPTOR 1B,OB-1
FUSED 5-HT1B
RECEPTOR,5-HYDROXYTR
YPTAMINE RECEPTOR 1B
(Homo
sapiens;
Spodoptera
frugiperda) 		6 / 12 TRP A 125
ASP A 129
SER A 212
PHE A 330
PHE A 331
TYR A 359
 None
89F  A1201 (-3.3A)
89F  A1201 ( 3.8A)
89F  A1201 (-4.1A)
89F  A1201 (-4.6A)
None
 0.67A 3nyaA-5v54A:
27.9		 3nyaA-5v54A:
11.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NYA_A_JTZA1203_1
(BETA-2 ADRENERGIC
RECEPTOR, LYSOZYME)		 5v54 5-HYDROXYTRYPTAMINE
RECEPTOR 1B,OB-1
FUSED 5-HT1B
RECEPTOR,5-HYDROXYTR
YPTAMINE RECEPTOR 1B
(Homo
sapiens;
Spodoptera
frugiperda) 		6 / 12 TRP A 125
ASP A 129
SER A 212
PHE A 330
PHE A 331
TYR A 359
 None
89F  A1201 (-3.3A)
89F  A1201 ( 3.8A)
89F  A1201 (-4.1A)
89F  A1201 (-4.6A)
None
 1.00A 3nyaA-5v54A:
27.9		 3nyaA-5v54A:
11.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RZE_A_D7VA1201_1
(HISTAMINE H1
RECEPTOR, LYSOZYME
CHIMERA)		 5v54 5-HYDROXYTRYPTAMINE
RECEPTOR 1B,OB-1
FUSED 5-HT1B
RECEPTOR,5-HYDROXYTR
YPTAMINE RECEPTOR 1B
(Homo
sapiens;
Spodoptera
frugiperda) 		6 / 12 ASP A 129
THR A 134
ILE A 137
TRP A 327
PHE A 331
TYR A 359
 89F  A1201 (-3.3A)
89F  A1201 (-4.2A)
None
89F  A1201 (-3.6A)
89F  A1201 (-4.6A)
None
 0.64A 3rzeA-5v54A:
28.3		 3rzeA-5v54A:
14.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AMJ_A_CVDA1359_1
(BETA-1 ADRENERGIC
RECEPTOR)		 5v54 5-HYDROXYTRYPTAMINE
RECEPTOR 1B,OB-1
FUSED 5-HT1B
RECEPTOR,5-HYDROXYTR
YPTAMINE RECEPTOR 1B
(Homo
sapiens;
Spodoptera
frugiperda) 		6 / 12 TRP A 125
ASP A 129
SER A 212
PHE A 330
PHE A 331
TYR A 359
 None
89F  A1201 (-3.3A)
89F  A1201 ( 3.8A)
89F  A1201 (-4.1A)
89F  A1201 (-4.6A)
None
 1.31A 4amjA-5v54A:
28.7		 4amjA-5v54A:
14.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AMJ_A_CVDA1359_1
(BETA-1 ADRENERGIC
RECEPTOR)		 5v54 5-HYDROXYTRYPTAMINE
RECEPTOR 1B,OB-1
FUSED 5-HT1B
RECEPTOR,5-HYDROXYTR
YPTAMINE RECEPTOR 1B
(Homo
sapiens;
Spodoptera
frugiperda) 		7 / 12 TRP A 125
ASP A 129
SER A 212
TRP A 327
PHE A 330
PHE A 331
TYR A 359
 None
89F  A1201 (-3.3A)
89F  A1201 ( 3.8A)
89F  A1201 (-3.6A)
89F  A1201 (-4.1A)
89F  A1201 (-4.6A)
None
 0.80A 4amjA-5v54A:
28.7		 4amjA-5v54A:
14.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AMJ_B_CVDB1360_1
(BETA-1 ADRENERGIC
RECEPTOR)		 5v54 5-HYDROXYTRYPTAMINE
RECEPTOR 1B,OB-1
FUSED 5-HT1B
RECEPTOR,5-HYDROXYTR
YPTAMINE RECEPTOR 1B
(Homo
sapiens;
Spodoptera
frugiperda) 		6 / 12 TRP A 125
ASP A 129
SER A 212
PHE A 330
PHE A 331
TYR A 359
 None
89F  A1201 (-3.3A)
89F  A1201 ( 3.8A)
89F  A1201 (-4.1A)
89F  A1201 (-4.6A)
None
 1.31A 4amjB-5v54A:
28.7		 4amjB-5v54A:
14.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AMJ_B_CVDB1360_1
(BETA-1 ADRENERGIC
RECEPTOR)		 5v54 5-HYDROXYTRYPTAMINE
RECEPTOR 1B,OB-1
FUSED 5-HT1B
RECEPTOR,5-HYDROXYTR
YPTAMINE RECEPTOR 1B
(Homo
sapiens;
Spodoptera
frugiperda) 		7 / 12 TRP A 125
ASP A 129
SER A 212
TRP A 327
PHE A 330
PHE A 331
TYR A 359
 None
89F  A1201 (-3.3A)
89F  A1201 ( 3.8A)
89F  A1201 (-3.6A)
89F  A1201 (-4.1A)
89F  A1201 (-4.6A)
None
 0.81A 4amjB-5v54A:
28.7		 4amjB-5v54A:
14.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IAQ_A_2GMA2001_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 5v54 5-HYDROXYTRYPTAMINE
RECEPTOR 1B,OB-1
FUSED 5-HT1B
RECEPTOR,5-HYDROXYTR
YPTAMINE RECEPTOR 1B
(Homo
sapiens;
Spodoptera
frugiperda) 		7 / 12 ASP A 129
CYH A 133
ALA A 216
TRP A 327
PHE A 330
PHE A 351
THR A 355
 89F  A1201 (-3.3A)
89F  A1201 (-4.5A)
89F  A1201 ( 3.9A)
89F  A1201 (-3.6A)
89F  A1201 (-4.1A)
None
89F  A1201 (-4.0A)
 0.91A 4iaqA-5v54A:
39.9		 4iaqA-5v54A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IAQ_A_2GMA2001_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 5v54 5-HYDROXYTRYPTAMINE
RECEPTOR 1B,OB-1
FUSED 5-HT1B
RECEPTOR,5-HYDROXYTR
YPTAMINE RECEPTOR 1B
(Homo
sapiens;
Spodoptera
frugiperda) 		8 / 12 ASP A 129
CYH A 133
TRP A 327
PHE A 330
PHE A 331
MET A 337
PHE A 351
THR A 355
 89F  A1201 (-3.3A)
89F  A1201 (-4.5A)
89F  A1201 (-3.6A)
89F  A1201 (-4.1A)
89F  A1201 (-4.6A)
None
None
89F  A1201 (-4.0A)
 1.24A 4iaqA-5v54A:
39.9		 4iaqA-5v54A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IAQ_A_2GMA2001_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 5v54 5-HYDROXYTRYPTAMINE
RECEPTOR 1B,OB-1
FUSED 5-HT1B
RECEPTOR,5-HYDROXYTR
YPTAMINE RECEPTOR 1B
(Homo
sapiens;
Spodoptera
frugiperda) 		7 / 12 ASP A 129
CYH A 133
VAL A 201
ALA A 216
TRP A 327
PHE A 330
THR A 355
 89F  A1201 (-3.3A)
89F  A1201 (-4.5A)
None
89F  A1201 ( 3.9A)
89F  A1201 (-3.6A)
89F  A1201 (-4.1A)
89F  A1201 (-4.0A)
 1.02A 4iaqA-5v54A:
39.9		 4iaqA-5v54A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IAQ_A_2GMA2001_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 5v54 5-HYDROXYTRYPTAMINE
RECEPTOR 1B,OB-1
FUSED 5-HT1B
RECEPTOR,5-HYDROXYTR
YPTAMINE RECEPTOR 1B
(Homo
sapiens;
Spodoptera
frugiperda) 		8 / 12 ASP A 129
CYH A 133
VAL A 201
TRP A 327
PHE A 330
PHE A 331
MET A 337
THR A 355
 89F  A1201 (-3.3A)
89F  A1201 (-4.5A)
None
89F  A1201 (-3.6A)
89F  A1201 (-4.1A)
89F  A1201 (-4.6A)
None
89F  A1201 (-4.0A)
 1.24A 4iaqA-5v54A:
39.9		 4iaqA-5v54A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IAQ_A_2GMA2001_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 5v54 5-HYDROXYTRYPTAMINE
RECEPTOR 1B,OB-1
FUSED 5-HT1B
RECEPTOR,5-HYDROXYTR
YPTAMINE RECEPTOR 1B
(Homo
sapiens;
Spodoptera
frugiperda) 		8 / 12 LEU A 126
ASP A 129
CYH A 133
ALA A 216
PHE A 330
LEU A 348
PHE A 351
THR A 355
 89F  A1201 (-4.9A)
89F  A1201 (-3.3A)
89F  A1201 (-4.5A)
89F  A1201 ( 3.9A)
89F  A1201 (-4.1A)
None
None
89F  A1201 (-4.0A)
 0.94A 4iaqA-5v54A:
39.9		 4iaqA-5v54A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IAQ_A_2GMA2001_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 5v54 5-HYDROXYTRYPTAMINE
RECEPTOR 1B,OB-1
FUSED 5-HT1B
RECEPTOR,5-HYDROXYTR
YPTAMINE RECEPTOR 1B
(Homo
sapiens;
Spodoptera
frugiperda) 		8 / 12 LEU A 126
ASP A 129
CYH A 133
PHE A 330
PHE A 331
LEU A 348
PHE A 351
THR A 355
 89F  A1201 (-4.9A)
89F  A1201 (-3.3A)
89F  A1201 (-4.5A)
89F  A1201 (-4.1A)
89F  A1201 (-4.6A)
None
None
89F  A1201 (-4.0A)
 0.88A 4iaqA-5v54A:
39.9		 4iaqA-5v54A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IAQ_A_2GMA2001_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 5v54 5-HYDROXYTRYPTAMINE
RECEPTOR 1B,OB-1
FUSED 5-HT1B
RECEPTOR,5-HYDROXYTR
YPTAMINE RECEPTOR 1B
(Homo
sapiens;
Spodoptera
frugiperda) 		8 / 12 LEU A 126
ASP A 129
CYH A 133
PHE A 330
PHE A 331
MET A 337
PHE A 351
THR A 355
 89F  A1201 (-4.9A)
89F  A1201 (-3.3A)
89F  A1201 (-4.5A)
89F  A1201 (-4.1A)
89F  A1201 (-4.6A)
None
None
89F  A1201 (-4.0A)
 1.20A 4iaqA-5v54A:
39.9		 4iaqA-5v54A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IAQ_A_2GMA2001_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 5v54 5-HYDROXYTRYPTAMINE
RECEPTOR 1B,OB-1
FUSED 5-HT1B
RECEPTOR,5-HYDROXYTR
YPTAMINE RECEPTOR 1B
(Homo
sapiens;
Spodoptera
frugiperda) 		7 / 12 LEU A 126
ASP A 129
CYH A 133
VAL A 201
ALA A 216
PHE A 330
THR A 355
 89F  A1201 (-4.9A)
89F  A1201 (-3.3A)
89F  A1201 (-4.5A)
None
89F  A1201 ( 3.9A)
89F  A1201 (-4.1A)
89F  A1201 (-4.0A)
 0.92A 4iaqA-5v54A:
39.9		 4iaqA-5v54A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IAQ_A_2GMA2001_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 5v54 5-HYDROXYTRYPTAMINE
RECEPTOR 1B,OB-1
FUSED 5-HT1B
RECEPTOR,5-HYDROXYTR
YPTAMINE RECEPTOR 1B
(Homo
sapiens;
Spodoptera
frugiperda) 		8 / 12 LEU A 126
ASP A 129
CYH A 133
VAL A 201
PHE A 330
PHE A 331
MET A 337
THR A 355
 89F  A1201 (-4.9A)
89F  A1201 (-3.3A)
89F  A1201 (-4.5A)
None
89F  A1201 (-4.1A)
89F  A1201 (-4.6A)
None
89F  A1201 (-4.0A)
 1.17A 4iaqA-5v54A:
39.9		 4iaqA-5v54A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IAQ_A_2GMA2001_2
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 5v54 5-HYDROXYTRYPTAMINE
RECEPTOR 1B,OB-1
FUSED 5-HT1B
RECEPTOR,5-HYDROXYTR
YPTAMINE RECEPTOR 1B
(Homo
sapiens;
Spodoptera
frugiperda) 		6 / 6 TRP A 125
ILE A 130
THR A 134
VAL A 200
SER A 212
ASP A 352
 None
89F  A1201 (-4.3A)
89F  A1201 (-4.2A)
None
89F  A1201 ( 3.8A)
None
 0.85A 4iaqA-5v54A:
39.9		 4iaqA-5v54A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IAR_A_ERMA2001_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 5v54 5-HYDROXYTRYPTAMINE
RECEPTOR 1B,OB-1
FUSED 5-HT1B
RECEPTOR,5-HYDROXYTR
YPTAMINE RECEPTOR 1B
(Homo
sapiens;
Spodoptera
frugiperda) 		7 / 12 ASP A 129
CYH A 133
ALA A 216
PHE A 330
LEU A 348
PHE A 351
THR A 355
 89F  A1201 (-3.3A)
89F  A1201 (-4.5A)
89F  A1201 ( 3.9A)
89F  A1201 (-4.1A)
None
None
89F  A1201 (-4.0A)
 0.74A 4iarA-5v54A:
41.3		 4iarA-5v54A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IAR_A_ERMA2001_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 5v54 5-HYDROXYTRYPTAMINE
RECEPTOR 1B,OB-1
FUSED 5-HT1B
RECEPTOR,5-HYDROXYTR
YPTAMINE RECEPTOR 1B
(Homo
sapiens;
Spodoptera
frugiperda) 		6 / 12 ASP A 129
CYH A 133
ALA A 216
TRP A 327
PHE A 330
LEU A 348
 89F  A1201 (-3.3A)
89F  A1201 (-4.5A)
89F  A1201 ( 3.9A)
89F  A1201 (-3.6A)
89F  A1201 (-4.1A)
None
 0.87A 4iarA-5v54A:
41.3		 4iarA-5v54A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IAR_A_ERMA2001_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 5v54 5-HYDROXYTRYPTAMINE
RECEPTOR 1B,OB-1
FUSED 5-HT1B
RECEPTOR,5-HYDROXYTR
YPTAMINE RECEPTOR 1B
(Homo
sapiens;
Spodoptera
frugiperda) 		6 / 12 ASP A 129
CYH A 133
PHE A 330
MET A 337
PHE A 351
THR A 355
 89F  A1201 (-3.3A)
89F  A1201 (-4.5A)
89F  A1201 (-4.1A)
None
None
89F  A1201 (-4.0A)
 1.17A 4iarA-5v54A:
41.3		 4iarA-5v54A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IAR_A_ERMA2001_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 5v54 5-HYDROXYTRYPTAMINE
RECEPTOR 1B,OB-1
FUSED 5-HT1B
RECEPTOR,5-HYDROXYTR
YPTAMINE RECEPTOR 1B
(Homo
sapiens;
Spodoptera
frugiperda) 		5 / 12 ASP A 129
CYH A 133
TRP A 327
PHE A 330
MET A 337
 89F  A1201 (-3.3A)
89F  A1201 (-4.5A)
89F  A1201 (-3.6A)
89F  A1201 (-4.1A)
None
 1.19A 4iarA-5v54A:
41.3		 4iarA-5v54A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IAR_A_ERMA2001_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 5v54 5-HYDROXYTRYPTAMINE
RECEPTOR 1B,OB-1
FUSED 5-HT1B
RECEPTOR,5-HYDROXYTR
YPTAMINE RECEPTOR 1B
(Homo
sapiens;
Spodoptera
frugiperda) 		6 / 12 CYH A 133
PHE A 330
SER A 334
LEU A 348
PHE A 351
THR A 355
 89F  A1201 (-4.5A)
89F  A1201 (-4.1A)
89F  A1201 ( 4.2A)
None
None
89F  A1201 (-4.0A)
 0.95A 4iarA-5v54A:
41.3		 4iarA-5v54A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IAR_A_ERMA2001_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 5v54 5-HYDROXYTRYPTAMINE
RECEPTOR 1B,OB-1
FUSED 5-HT1B
RECEPTOR,5-HYDROXYTR
YPTAMINE RECEPTOR 1B
(Homo
sapiens;
Spodoptera
frugiperda) 		5 / 12 CYH A 133
TRP A 327
PHE A 330
SER A 334
LEU A 348
 89F  A1201 (-4.5A)
89F  A1201 (-3.6A)
89F  A1201 (-4.1A)
89F  A1201 ( 4.2A)
None
 0.93A 4iarA-5v54A:
41.3		 4iarA-5v54A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IAR_A_ERMA2001_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 5v54 5-HYDROXYTRYPTAMINE
RECEPTOR 1B,OB-1
FUSED 5-HT1B
RECEPTOR,5-HYDROXYTR
YPTAMINE RECEPTOR 1B
(Homo
sapiens;
Spodoptera
frugiperda) 		8 / 12 LEU A 126
ASP A 129
CYH A 133
VAL A 201
ALA A 216
PHE A 330
LEU A 348
THR A 355
 89F  A1201 (-4.9A)
89F  A1201 (-3.3A)
89F  A1201 (-4.5A)
None
89F  A1201 ( 3.9A)
89F  A1201 (-4.1A)
None
89F  A1201 (-4.0A)
 0.83A 4iarA-5v54A:
41.3		 4iarA-5v54A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IAR_A_ERMA2001_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 5v54 5-HYDROXYTRYPTAMINE
RECEPTOR 1B,OB-1
FUSED 5-HT1B
RECEPTOR,5-HYDROXYTR
YPTAMINE RECEPTOR 1B
(Homo
sapiens;
Spodoptera
frugiperda) 		7 / 12 LEU A 126
ASP A 129
CYH A 133
VAL A 201
PHE A 330
MET A 337
THR A 355
 89F  A1201 (-4.9A)
89F  A1201 (-3.3A)
89F  A1201 (-4.5A)
None
89F  A1201 (-4.1A)
None
89F  A1201 (-4.0A)
 1.11A 4iarA-5v54A:
41.3		 4iarA-5v54A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IAR_A_ERMA2001_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 5v54 5-HYDROXYTRYPTAMINE
RECEPTOR 1B,OB-1
FUSED 5-HT1B
RECEPTOR,5-HYDROXYTR
YPTAMINE RECEPTOR 1B
(Homo
sapiens;
Spodoptera
frugiperda) 		7 / 12 LEU A 126
CYH A 133
VAL A 201
PHE A 330
SER A 334
LEU A 348
THR A 355
 89F  A1201 (-4.9A)
89F  A1201 (-4.5A)
None
89F  A1201 (-4.1A)
89F  A1201 ( 4.2A)
None
89F  A1201 (-4.0A)
 0.88A 4iarA-5v54A:
41.3		 4iarA-5v54A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IAR_A_ERMA2001_2
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 5v54 5-HYDROXYTRYPTAMINE
RECEPTOR 1B,OB-1
FUSED 5-HT1B
RECEPTOR,5-HYDROXYTR
YPTAMINE RECEPTOR 1B
(Homo
sapiens;
Spodoptera
frugiperda) 		5 / 7 TRP A 125
ILE A 130
SER A 212
PHE A 331
ASP A 352
 None
89F  A1201 (-4.3A)
89F  A1201 ( 3.8A)
89F  A1201 (-4.6A)
None
 0.58A 4iarA-5v54A:
41.3		 4iarA-5v54A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IAR_A_ERMA2001_2
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 5v54 5-HYDROXYTRYPTAMINE
RECEPTOR 1B,OB-1
FUSED 5-HT1B
RECEPTOR,5-HYDROXYTR
YPTAMINE RECEPTOR 1B
(Homo
sapiens;
Spodoptera
frugiperda) 		5 / 7 TRP A 125
ILE A 130
THR A 134
SER A 212
ASP A 352
 None
89F  A1201 (-4.3A)
89F  A1201 (-4.2A)
89F  A1201 ( 3.8A)
None
 0.47A 4iarA-5v54A:
41.3		 4iarA-5v54A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IAR_A_ERMA2001_2
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 5v54 5-HYDROXYTRYPTAMINE
RECEPTOR 1B,OB-1
FUSED 5-HT1B
RECEPTOR,5-HYDROXYTR
YPTAMINE RECEPTOR 1B
(Homo
sapiens;
Spodoptera
frugiperda) 		5 / 7 TRP A 125
ILE A 130
THR A 134
VAL A 200
SER A 212
 None
89F  A1201 (-4.3A)
89F  A1201 (-4.2A)
None
89F  A1201 ( 3.8A)
 0.64A 4iarA-5v54A:
41.3		 4iarA-5v54A:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUD_A_ERMA2001_1
(5-HYDROXYTRYPTAMINE
RECEPTOR 2B,SOLUBLE
CYTOCHROME B562
CHIMERA)		 5v54 5-HYDROXYTRYPTAMINE
RECEPTOR 1B,OB-1
FUSED 5-HT1B
RECEPTOR,5-HYDROXYTR
YPTAMINE RECEPTOR 1B
(Homo
sapiens;
Spodoptera
frugiperda) 		5 / 12 LEU A 126
ASP A 129
ALA A 216
PHE A 330
PHE A 331
 89F  A1201 (-4.9A)
89F  A1201 (-3.3A)
89F  A1201 ( 3.9A)
89F  A1201 (-4.1A)
89F  A1201 (-4.6A)
 0.91A 5tudA-5v54A:
34.3		 5tudA-5v54A:
9.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A93_A_8NUA3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 5v54 5-HYDROXYTRYPTAMINE
RECEPTOR 1B,OB-1
FUSED 5-HT1B
RECEPTOR,5-HYDROXYTR
YPTAMINE RECEPTOR 1B
(Spodoptera
frugiperda;
Homo
sapiens) 		8 / 12 SER A 106
TRP A 125
THR A 134
ILE A 137
PHE A 323
TRP A 327
PHE A 330
PHE A 331
 None
None
89F  A1201 (-4.2A)
None
None
89F  A1201 (-3.6A)
89F  A1201 (-4.1A)
89F  A1201 (-4.6A)
 0.87A 6a93A-5v54A:
32.7		 6a93A-5v54A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A93_A_8NUA3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 5v54 5-HYDROXYTRYPTAMINE
RECEPTOR 1B,OB-1
FUSED 5-HT1B
RECEPTOR,5-HYDROXYTR
YPTAMINE RECEPTOR 1B
(Spodoptera
frugiperda;
Homo
sapiens) 		8 / 12 SER A 106
TRP A 125
THR A 134
ILE A 137
TRP A 327
PHE A 330
PHE A 331
TYR A 359
 None
None
89F  A1201 (-4.2A)
None
89F  A1201 (-3.6A)
89F  A1201 (-4.1A)
89F  A1201 (-4.6A)
None
 0.63A 6a93A-5v54A:
32.7		 6a93A-5v54A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A93_B_8NUB3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 5v54 5-HYDROXYTRYPTAMINE
RECEPTOR 1B,OB-1
FUSED 5-HT1B
RECEPTOR,5-HYDROXYTR
YPTAMINE RECEPTOR 1B
(Spodoptera
frugiperda;
Homo
sapiens) 		6 / 12 SER A 106
TRP A 125
THR A 134
TRP A 327
PHE A 330
PHE A 331
 None
None
89F  A1201 (-4.2A)
89F  A1201 (-3.6A)
89F  A1201 (-4.1A)
89F  A1201 (-4.6A)
 0.53A 6a93B-5v54A:
33.5		 6a93B-5v54A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A94_B_ZOTB3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 5v54 5-HYDROXYTRYPTAMINE
RECEPTOR 1B,OB-1
FUSED 5-HT1B
RECEPTOR,5-HYDROXYTR
YPTAMINE RECEPTOR 1B
(Spodoptera
frugiperda;
Homo
sapiens) 		5 / 12 THR A 134
PHE A 323
TRP A 327
PHE A 330
PHE A 331
 89F  A1201 (-4.2A)
None
89F  A1201 (-3.6A)
89F  A1201 (-4.1A)
89F  A1201 (-4.6A)
 0.93A 6a94B-5v54A:
33.0		 6a94B-5v54A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CM4_A_8NUA2001_0
(D(2) DOPAMINE
RECEPTOR, ENDOLYSIN
CHIMERA)		 5v54 5-HYDROXYTRYPTAMINE
RECEPTOR 1B,OB-1
FUSED 5-HT1B
RECEPTOR,5-HYDROXYTR
YPTAMINE RECEPTOR 1B
(Spodoptera
frugiperda;
Homo
sapiens) 		6 / 12 CYH A 133
THR A 134
TRP A 327
PHE A 331
THR A 355
TYR A 359
 89F  A1201 (-4.5A)
89F  A1201 (-4.2A)
89F  A1201 (-3.6A)
89F  A1201 (-4.6A)
89F  A1201 (-4.0A)
None
 0.42A 6cm4A-5v54A:
27.1		 6cm4A-5v54A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CM4_A_8NUA2001_0
(D(2) DOPAMINE
RECEPTOR, ENDOLYSIN
CHIMERA)		 5v54 5-HYDROXYTRYPTAMINE
RECEPTOR 1B,OB-1
FUSED 5-HT1B
RECEPTOR,5-HYDROXYTR
YPTAMINE RECEPTOR 1B
(Spodoptera
frugiperda;
Homo
sapiens) 		5 / 12 THR A 134
PHE A 323
TRP A 327
PHE A 331
THR A 355
 89F  A1201 (-4.2A)
None
89F  A1201 (-3.6A)
89F  A1201 (-4.6A)
89F  A1201 (-4.0A)
 0.79A 6cm4A-5v54A:
27.1		 6cm4A-5v54A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DRX_A_H8GA1201_0
(5HT2B RECEPTOR, BRIL
CHIMERA)		 5v54 5-HYDROXYTRYPTAMINE
RECEPTOR 1B,OB-1
FUSED 5-HT1B
RECEPTOR,5-HYDROXYTR
YPTAMINE RECEPTOR 1B
(Spodoptera
frugiperda;
Homo
sapiens) 		5 / 12 LEU A 126
THR A 134
ALA A 216
PHE A 330
TYR A 359
 89F  A1201 (-4.9A)
89F  A1201 (-4.2A)
89F  A1201 ( 3.9A)
89F  A1201 (-4.1A)
None
 0.97A 6drxA-5v54A:
32.3		 6drxA-5v54A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DRX_A_H8GA1201_0
(5HT2B RECEPTOR, BRIL
CHIMERA)		 5v54 5-HYDROXYTRYPTAMINE
RECEPTOR 1B,OB-1
FUSED 5-HT1B
RECEPTOR,5-HYDROXYTR
YPTAMINE RECEPTOR 1B
(Spodoptera
frugiperda;
Homo
sapiens) 		5 / 12 THR A 134
ALA A 216
TRP A 327
PHE A 330
TYR A 359
 89F  A1201 (-4.2A)
89F  A1201 ( 3.9A)
89F  A1201 (-3.6A)
89F  A1201 (-4.1A)
None
 0.77A 6drxA-5v54A:
32.3		 6drxA-5v54A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DRX_A_H8GA1201_0
(5HT2B RECEPTOR, BRIL
CHIMERA)		 5v54 5-HYDROXYTRYPTAMINE
RECEPTOR 1B,OB-1
FUSED 5-HT1B
RECEPTOR,5-HYDROXYTR
YPTAMINE RECEPTOR 1B
(Spodoptera
frugiperda;
Homo
sapiens) 		5 / 12 TRP A 125
LEU A 126
THR A 134
ALA A 216
PHE A 330
 None
89F  A1201 (-4.9A)
89F  A1201 (-4.2A)
89F  A1201 ( 3.9A)
89F  A1201 (-4.1A)
 0.96A 6drxA-5v54A:
32.3		 6drxA-5v54A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DRY_A_H8DA2001_0
(5HT2B RECEPTOR, BRIL
CHIMERA)		 5v54 5-HYDROXYTRYPTAMINE
RECEPTOR 1B,OB-1
FUSED 5-HT1B
RECEPTOR,5-HYDROXYTR
YPTAMINE RECEPTOR 1B
(Spodoptera
frugiperda;
Homo
sapiens) 		5 / 11 ASP A 129
THR A 134
ALA A 216
PHE A 330
TYR A 359
 89F  A1201 (-3.3A)
89F  A1201 (-4.2A)
89F  A1201 ( 3.9A)
89F  A1201 (-4.1A)
None
 0.69A 6dryA-5v54A:
33.8		 6dryA-5v54A:
undetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6H7J_A_5FWA401_0
(BETA-1 ADRENERGIC
RECEPTOR)		 5v54 5-HYDROXYTRYPTAMINE
RECEPTOR 1B,OB-1
FUSED 5-HT1B
RECEPTOR,5-HYDROXYTR
YPTAMINE RECEPTOR 1B
(Spodoptera
frugiperda;
Homo
sapiens) 		6 / 12 TRP A 125
ASP A 129
SER A 212
PHE A 330
PHE A 331
TYR A 359
 None
89F  A1201 (-3.3A)
89F  A1201 ( 3.8A)
89F  A1201 (-4.1A)
89F  A1201 (-4.6A)
None
 0.71A 6h7jA-5v54A:
28.2		 6h7jA-5v54A:
32.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6H7J_B_5FWB402_0
(BETA-1 ADRENERGIC
RECEPTOR)		 5v54 5-HYDROXYTRYPTAMINE
RECEPTOR 1B,OB-1
FUSED 5-HT1B
RECEPTOR,5-HYDROXYTR
YPTAMINE RECEPTOR 1B
(Spodoptera
frugiperda;
Homo
sapiens) 		6 / 12 TRP A 125
ASP A 129
SER A 212
PHE A 330
PHE A 331
TYR A 359
 None
89F  A1201 (-3.3A)
89F  A1201 ( 3.8A)
89F  A1201 (-4.1A)
89F  A1201 (-4.6A)
None
 0.70A 6h7jB-5v54A:
28.8		 6h7jB-5v54A:
32.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6H7L_A_Y00A406_0
(BETA-1 ADRENERGIC
RECEPTOR)		 5v54 5-HYDROXYTRYPTAMINE
RECEPTOR 1B,OB-1
FUSED 5-HT1B
RECEPTOR,5-HYDROXYTR
YPTAMINE RECEPTOR 1B
(Spodoptera
frugiperda;
Homo
sapiens) 		5 / 12 TRP A 125
ASP A 129
SER A 212
TRP A 356
TYR A 359
 None
89F  A1201 (-3.3A)
89F  A1201 ( 3.8A)
None
None
 0.85A 6h7lA-5v54A:
28.2		 6h7lA-5v54A:
32.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6H7L_B_Y00B405_0
(BETA-1 ADRENERGIC
RECEPTOR)		 5v54 5-HYDROXYTRYPTAMINE
RECEPTOR 1B,OB-1
FUSED 5-HT1B
RECEPTOR,5-HYDROXYTR
YPTAMINE RECEPTOR 1B
(Spodoptera
frugiperda;
Homo
sapiens) 		5 / 12 TRP A 125
ASP A 129
SER A 212
TRP A 356
TYR A 359
 None
89F  A1201 (-3.3A)
89F  A1201 ( 3.8A)
None
None
 0.85A 6h7lB-5v54A:
28.5		 6h7lB-5v54A:
32.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6H7M_A_68HA504_0
(BETA-1 ADRENERGIC
RECEPTOR)		 5v54 5-HYDROXYTRYPTAMINE
RECEPTOR 1B,OB-1
FUSED 5-HT1B
RECEPTOR,5-HYDROXYTR
YPTAMINE RECEPTOR 1B
(Spodoptera
frugiperda;
Homo
sapiens) 		6 / 12 TRP A 125
ASP A 129
SER A 212
PHE A 330
PHE A 331
TYR A 359
 None
89F  A1201 (-3.3A)
89F  A1201 ( 3.8A)
89F  A1201 (-4.1A)
89F  A1201 (-4.6A)
None
 0.65A 6h7mA-5v54A:
28.3		 6h7mA-5v54A:
32.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6H7M_B_68HB405_0
(BETA-1 ADRENERGIC
RECEPTOR)		 5v54 5-HYDROXYTRYPTAMINE
RECEPTOR 1B,OB-1
FUSED 5-HT1B
RECEPTOR,5-HYDROXYTR
YPTAMINE RECEPTOR 1B
(Spodoptera
frugiperda;
Homo
sapiens) 		6 / 12 TRP A 125
ASP A 129
SER A 212
PHE A 330
PHE A 331
TYR A 359
 None
89F  A1201 (-3.3A)
89F  A1201 ( 3.8A)
89F  A1201 (-4.1A)
89F  A1201 (-4.6A)
None
 0.65A 6h7mB-5v54A:
28.5		 6h7mB-5v54A:
32.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HLP_A_GAWA1501_0
(SUBSTANCE-P
RECEPTOR,SUBSTANCE-P
RECEPTOR)		 5v54 5-HYDROXYTRYPTAMINE
RECEPTOR 1B,OB-1
FUSED 5-HT1B
RECEPTOR,5-HYDROXYTR
YPTAMINE RECEPTOR 1B
(Spodoptera
frugiperda;
Homo
sapiens) 		5 / 12 ILE A 130
THR A 213
TRP A 327
PHE A 330
PRO A 338
 89F  A1201 (-4.3A)
89F  A1201 (-3.9A)
89F  A1201 (-3.6A)
89F  A1201 (-4.1A)
None
 1.04A 6hlpA-5v54A:
26.6		 6hlpA-5v54A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IBL_A_H98A501_0
(THIOREDOXIN 1,BETA-1
ADRENERGIC RECEPTOR)		 5v54 5-HYDROXYTRYPTAMINE
RECEPTOR 1B,OB-1
FUSED 5-HT1B
RECEPTOR,5-HYDROXYTR
YPTAMINE RECEPTOR 1B
(Spodoptera
frugiperda;
Homo
sapiens) 		5 / 12 TRP A 125
TRP A 327
PHE A 330
PHE A 331
TYR A 359
 None
89F  A1201 (-3.6A)
89F  A1201 (-4.1A)
89F  A1201 (-4.6A)
None
 0.60A 6iblA-5v54A:
28.1		 6iblA-5v54A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IBL_B_H98B501_0
(THIOREDOXIN 1,BETA-1
ADRENERGIC RECEPTOR)		 5v54 5-HYDROXYTRYPTAMINE
RECEPTOR 1B,OB-1
FUSED 5-HT1B
RECEPTOR,5-HYDROXYTR
YPTAMINE RECEPTOR 1B
(Spodoptera
frugiperda;
Homo
sapiens) 		5 / 12 TRP A 125
TRP A 327
PHE A 330
PHE A 331
TYR A 359
 None
89F  A1201 (-3.6A)
89F  A1201 (-4.1A)
89F  A1201 (-4.6A)
None
 0.62A 6iblB-5v54A:
28.2		 6iblB-5v54A:
undetectable