SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '83D'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2A3A_A_TEPA1435_1 (CHITINASE)	5u8z	CAROTENOID OXYGENASE 1 (Neurospora crassa)	3 / 3	TRP A 278 GLU A 165 TYR A 212	None 83D A 602 (-3.7A) None	1.26A	2a3aA-5u8zA: undetectable	2a3aA-5u8zA: 21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3CAJ_A_EZLA265_1 (CARBONIC ANHYDRASE 2)	5u8z	CAROTENOID OXYGENASE 1 (Neurospora crassa)	5 / 10	HIS A 248 HIS A 197 HIS A 313 THR A 151 PRO A 77	FE2 A 601 ( 3.4A) FE2 A 601 (-3.3A) FE2 A 601 ( 3.4A) 83D A 602 (-3.5A) None	1.31A	3cajA-5u8zA: undetectable	3cajA-5u8zA: 19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UZZ_A_TESA501_1 (3-OXO-5-BETA-STEROID 4-DEHYDROGENASE)	5u8z	CAROTENOID OXYGENASE 1 (Neurospora crassa)	4 / 7	HIS A 248 TYR A 133 TRP A 90 TRP A 340	FE2 A 601 ( 3.4A) 83D A 602 (-4.4A) None None	1.27A	3uzzA-5u8zA: undetectable	3uzzA-5u8zA: 21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3V35_A_NTIA317_1 (ALDOSE REDUCTASE)	5u8z	CAROTENOID OXYGENASE 1 (Neurospora crassa)	4 / 8	HIS A 313 PHE A 337 PRO A 77 TRP A 90	FE2 A 601 ( 3.4A) 83D A 602 (-4.6A) None None	1.39A	3v35A-5u8zA: undetectable	3v35A-5u8zA: 20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5OGJ_A_ACTA307_0 (CARBONIC ANHYDRASE 13)	5u8z	CAROTENOID OXYGENASE 1 (Neurospora crassa)	4 / 6	HIS A 197 HIS A 248 LEU A 163 THR A 151	FE2 A 601 (-3.3A) FE2 A 601 ( 3.4A) None 83D A 602 (-3.5A)	1.15A	5ogjA-5u8zA: undetectable	5ogjA-5u8zA: 20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5OGJ_B_ACTB305_0 (CARBONIC ANHYDRASE 13)	5u8z	CAROTENOID OXYGENASE 1 (Neurospora crassa)	4 / 6	HIS A 197 HIS A 248 LEU A 163 THR A 151	FE2 A 601 (-3.3A) FE2 A 601 ( 3.4A) None 83D A 602 (-3.5A)	1.17A	5ogjB-5u8zA: undetectable	5ogjB-5u8zA: 20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5OHH_A_ACTA307_0 (CARBONIC ANHYDRASE 13)	5u8z	CAROTENOID OXYGENASE 1 (Neurospora crassa)	4 / 5	HIS A 197 HIS A 248 LEU A 163 THR A 151	FE2 A 601 (-3.3A) FE2 A 601 ( 3.4A) None 83D A 602 (-3.5A)	1.17A	5ohhA-5u8zA: undetectable	5ohhA-5u8zA: 20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5OHH_B_ACTB311_0 (CARBONIC ANHYDRASE 13)	5u8z	CAROTENOID OXYGENASE 1 (Neurospora crassa)	4 / 6	HIS A 197 HIS A 248 LEU A 163 THR A 151	FE2 A 601 (-3.3A) FE2 A 601 ( 3.4A) None 83D A 602 (-3.5A)	1.16A	5ohhB-5u8zA: undetectable	5ohhB-5u8zA: 20.72

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2A3A_A_TEPA1435_1","CHITINASE","5u8z","CAROTENOID OXYGENASE 1","Neurospora crassa",3,"TRP A 278;GLU A 165;TYR A 212","None;83D A 602 (-3.7A);None","1.26A","2a3aA-5u8zA:undetectable",null],["3CAJ_A_EZLA265_1","CARBONIC ANHYDRASE 2","5u8z","CAROTENOID OXYGENASE 1","Neurospora crassa",5,"HIS A 248;HIS A 197;HIS A 313;THR A 151;PRO A  77","FE2 A 601 ( 3.4A);FE2 A 601 (-3.3A);FE2 A 601 ( 3.4A);83D A 602 (-3.5A);None","1.31A","3cajA-5u8zA:undetectable","2a3aA-5u8zA:21.47"],["3UZZ_A_TESA501_1","3-OXO-5-BETA-STEROID 4-DEHYDROGENASE","5u8z","CAROTENOID OXYGENASE 1","Neurospora crassa",4,"HIS A 248;TYR A 133;TRP A  90;TRP A 340","FE2 A 601 ( 3.4A);83D A 602 (-4.4A);None;None","1.27A","3uzzA-5u8zA:undetectable","3cajA-5u8zA:19.73"],["3V35_A_NTIA317_1","ALDOSE REDUCTASE","5u8z","CAROTENOID OXYGENASE 1","Neurospora crassa",4,"HIS A 313;PHE A 337;PRO A  77;TRP A  90","FE2 A 601 ( 3.4A);83D A 602 (-4.6A);None;None","1.39A","3v35A-5u8zA:undetectable","3uzzA-5u8zA:21.55"],["5OGJ_A_ACTA307_0","CARBONIC ANHYDRASE 13","5u8z","CAROTENOID OXYGENASE 1","Neurospora crassa",4,"HIS A 197;HIS A 248;LEU A 163;THR A 151","FE2 A 601 (-3.3A);FE2 A 601 ( 3.4A);None;83D A 602 (-3.5A)","1.15A","5ogjA-5u8zA:undetectable","3v35A-5u8zA:20.34"],["5OGJ_B_ACTB305_0","CARBONIC ANHYDRASE 13","5u8z","CAROTENOID OXYGENASE 1","Neurospora crassa",4,"HIS A 197;HIS A 248;LEU A 163;THR A 151","FE2 A 601 (-3.3A);FE2 A 601 ( 3.4A);None;83D A 602 (-3.5A)","1.17A","5ogjB-5u8zA:undetectable","5ogjA-5u8zA:20.72"],["5OHH_A_ACTA307_0","CARBONIC ANHYDRASE 13","5u8z","CAROTENOID OXYGENASE 1","Neurospora crassa",4,"HIS A 197;HIS A 248;LEU A 163;THR A 151","FE2 A 601 (-3.3A);FE2 A 601 ( 3.4A);None;83D A 602 (-3.5A)","1.17A","5ohhA-5u8zA:undetectable","5ogjB-5u8zA:20.72"],["5OHH_B_ACTB311_0","CARBONIC ANHYDRASE 13","5u8z","CAROTENOID OXYGENASE 1","Neurospora crassa",4,"HIS A 197;HIS A 248;LEU A 163;THR A 151","FE2 A 601 (-3.3A);FE2 A 601 ( 3.4A);None;83D A 602 (-3.5A)","1.16A","5ohhB-5u8zA:undetectable","5ohhA-5u8zA:20.72"]]