SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '7WY'
DrReposER ID / Desc. | Hit PDBID |
Hit Macromolecule |
Res. Matches |
Interface | HETATM | RMSD | Dali Z-score |
Seq. Identity (%) |
View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3U5J_A_08HA1_1 (BROMODOMAIN-CONTAINING PROTEIN 4) |
5u6v | BROMODOMAIN-CONTAINING PROTEIN 2 (Homosapiens) | 6 / 7 | TRP A 370PRO A 371LEU A 381LEU A 383ASN A 429MET A 438 | None7WY A 501 (-4.4A)7WY A 501 (-4.9A)None7WY A 501 (-3.4A)7WY A 501 ( 3.9A) | 0.39A | 3u5jA-5u6vA:17.9 | 3u5jA-5u6vA:40.62 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3U5K_A_08JA1_1 (BROMODOMAIN-CONTAINING PROTEIN 4) |
5u6v | BROMODOMAIN-CONTAINING PROTEIN 2 (Homosapiens) | 7 / 8 | TRP A 370PRO A 371VAL A 376LEU A 381LEU A 383ASN A 429MET A 438 | None7WY A 501 (-4.4A)7WY A 501 ( 4.5A)7WY A 501 (-4.9A)None7WY A 501 (-3.4A)7WY A 501 ( 3.9A) | 0.41A | 3u5kA-5u6vA:18.0 | 3u5kA-5u6vA:40.62 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3U5K_B_08JB2_1 (BROMODOMAIN-CONTAINING PROTEIN 4) |
5u6v | BROMODOMAIN-CONTAINING PROTEIN 2 (Homosapiens) | 6 / 7 | TRP A 370PRO A 371VAL A 376LEU A 381LEU A 383ASN A 429 | None7WY A 501 (-4.4A)7WY A 501 ( 4.5A)7WY A 501 (-4.9A)None7WY A 501 (-3.4A) | 0.38A | 3u5kB-5u6vA:18.1 | 3u5kB-5u6vA:40.62 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3U5K_C_08JC3_1 (BROMODOMAIN-CONTAINING PROTEIN 4) |
5u6v | BROMODOMAIN-CONTAINING PROTEIN 2 (Homosapiens) | 7 / 8 | TRP A 370PRO A 371VAL A 376LEU A 381LEU A 383ASN A 429MET A 438 | None7WY A 501 (-4.4A)7WY A 501 ( 4.5A)7WY A 501 (-4.9A)None7WY A 501 (-3.4A)7WY A 501 ( 3.9A) | 0.48A | 3u5kC-5u6vA:17.6 | 3u5kC-5u6vA:40.62 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3U5K_D_08JD4_1 (BROMODOMAIN-CONTAINING PROTEIN 4) |
5u6v | BROMODOMAIN-CONTAINING PROTEIN 2 (Homosapiens) | 7 / 8 | TRP A 370PRO A 371VAL A 376LEU A 381LEU A 383ASN A 429MET A 438 | None7WY A 501 (-4.4A)7WY A 501 ( 4.5A)7WY A 501 (-4.9A)None7WY A 501 (-3.4A)7WY A 501 ( 3.9A) | 0.48A | 3u5kD-5u6vA:18.0 | 3u5kD-5u6vA:40.62 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4A9J_A_TYLA1188_1 (BROMODOMAINCONTAINING 2) |
5u6v | BROMODOMAIN-CONTAINING PROTEIN 2 (Homosapiens) | 4 / 5 | VAL A 376LEU A 381LEU A 383ASN A 429 | 7WY A 501 ( 4.5A)7WY A 501 (-4.9A)None7WY A 501 (-3.4A) | 0.39A | 4a9jA-5u6vA:19.2 | 4a9jA-5u6vA:39.62 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4A9J_B_TYLB1187_1 (BROMODOMAINCONTAINING 2) |
5u6v | BROMODOMAIN-CONTAINING PROTEIN 2 (Homosapiens) | 4 / 5 | VAL A 376LEU A 381LEU A 383ASN A 429 | 7WY A 501 ( 4.5A)7WY A 501 (-4.9A)None7WY A 501 (-3.4A) | 0.33A | 4a9jB-5u6vA:19.2 | 4a9jB-5u6vA:39.62 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4A9J_C_TYLC1184_1 (BROMODOMAINCONTAINING 2) |
5u6v | BROMODOMAIN-CONTAINING PROTEIN 2 (Homosapiens) | 4 / 5 | VAL A 376LEU A 381LEU A 383ASN A 429 | 7WY A 501 ( 4.5A)7WY A 501 (-4.9A)None7WY A 501 (-3.4A) | 0.33A | 4a9jC-5u6vA:19.5 | 4a9jC-5u6vA:39.62 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4A9K_A_TYLA2200_1 (CREB-BINDING PROTEIN) |
5u6v | BROMODOMAIN-CONTAINING PROTEIN 2 (Homosapiens) | 5 / 6 | VAL A 376LEU A 381TYR A 428ASN A 429VAL A 435 | 7WY A 501 ( 4.5A)7WY A 501 (-4.9A)None7WY A 501 (-3.4A)7WY A 501 (-4.1A) | 0.58A | 4a9kA-5u6vA:17.7 | 4a9kA-5u6vA:36.54 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4A9K_B_TYLB2198_1 (CREB-BINDING PROTEIN) |
5u6v | BROMODOMAIN-CONTAINING PROTEIN 2 (Homosapiens) | 4 / 5 | VAL A 376LEU A 381ASN A 429VAL A 435 | 7WY A 501 ( 4.5A)7WY A 501 (-4.9A)7WY A 501 (-3.4A)7WY A 501 (-4.1A) | 0.46A | 4a9kB-5u6vA:18.1 | 4a9kB-5u6vA:36.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4C66_A_H4CA1168_0 (BROMODOMAIN-CONTAINING PROTEIN 4) |
5u6v | BROMODOMAIN-CONTAINING PROTEIN 2 (Homosapiens) | 7 / 9 | TRP A 370PRO A 371VAL A 376LEU A 381LEU A 383ASN A 429MET A 438 | None7WY A 501 (-4.4A)7WY A 501 ( 4.5A)7WY A 501 (-4.9A)None7WY A 501 (-3.4A)7WY A 501 ( 3.9A) | 0.40A | 4c66A-5u6vA:18.0 | 4c66A-5u6vA:undetectable | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5PBE_A_TYLA2001_1 (BROMODOMAIN ADJACENTTO ZINC FINGERDOMAIN PROTEIN 2B) |
5u6v | BROMODOMAIN-CONTAINING PROTEIN 2 (Homosapiens) | 4 / 6 | PRO A 371VAL A 376TYR A 386ASN A 429 | 7WY A 501 (-4.4A)7WY A 501 ( 4.5A)None7WY A 501 (-3.4A) | 0.65A | 5pbeA-5u6vA:17.0 | 5pbeA-5u6vA:32.11 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5Y1Y_A_HNQA201_1 (BROMODOMAIN-CONTAINING PROTEIN 4) |
5u6v | BROMODOMAIN-CONTAINING PROTEIN 2 (Homosapiens) | 7 / 8 | PRO A 371VAL A 376LEU A 381LEU A 383CYH A 425TYR A 428ASN A 429 | 7WY A 501 (-4.4A)7WY A 501 ( 4.5A)7WY A 501 (-4.9A)None7WY A 501 ( 3.8A)None7WY A 501 (-3.4A) | 0.39A | 5y1yA-5u6vA:18.1 | 5y1yA-5u6vA:41.05 |