SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '7WV'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1TT0_C_ACTC6901_0 (PYRANOSE OXIDASE)	5u6s	UDP-GLYCOSYLTRANSFER ASE 74F2 (Arabidopsis thaliana)	4 / 6	THR A 365 GLN A 134 PHE A 170 PHE A 113	7WV A 504 (-3.2A) 7WV A 504 (-3.0A) None 7WV A 504 (-4.8A)	1.46A	1tt0C-5u6sA: 2.6	1tt0C-5u6sA: 21.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5U6M_A_SALA503_1 (UDP-GLYCOSYLTRANSFER ASE 74F2)	5u6s	UDP-GLYCOSYLTRANSFER ASE 74F2 (Arabidopsis thaliana)	7 / 7	THR A 15 HIS A 18 PHE A 113 GLN A 134 MET A 183 MET A 274 THR A 365	7WV A 504 (-3.7A) 7WV A 504 (-4.6A) 7WV A 504 (-4.8A) 7WV A 504 (-3.0A) None 7WV A 504 ( 3.5A) 7WV A 504 (-3.2A)	0.38A	5u6mA-5u6sA: 65.4	5u6mA-5u6sA: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5U6M_B_SALB503_1 (UDP-GLYCOSYLTRANSFER ASE 74F2)	5u6s	UDP-GLYCOSYLTRANSFER ASE 74F2 (Arabidopsis thaliana)	7 / 7	THR A 15 HIS A 18 PHE A 113 GLN A 134 MET A 183 MET A 274 THR A 365	7WV A 504 (-3.7A) 7WV A 504 (-4.6A) 7WV A 504 (-4.8A) 7WV A 504 (-3.0A) None 7WV A 504 ( 3.5A) 7WV A 504 (-3.2A)	0.31A	5u6mB-5u6sA: 66.8	5u6mB-5u6sA: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5U6N_A_SALA505_1 (UDP-GLYCOSYLTRANSFER ASE 74F2)	5u6s	UDP-GLYCOSYLTRANSFER ASE 74F2 (Arabidopsis thaliana)	7 / 8	HIS A 18 PHE A 113 GLN A 134 MET A 183 MET A 274 TRP A 364 THR A 365	7WV A 504 (-4.6A) 7WV A 504 (-4.8A) 7WV A 504 (-3.0A) None 7WV A 504 ( 3.5A) BGC A 501 (-4.2A) 7WV A 504 (-3.2A)	0.31A	5u6nA-5u6sA: 66.1	5u6nA-5u6sA: 99.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5U6N_B_SALB504_1 (UDP-GLYCOSYLTRANSFER ASE 74F2)	5u6s	UDP-GLYCOSYLTRANSFER ASE 74F2 (Arabidopsis thaliana)	5 / 6	HIS A 18 PHE A 113 GLN A 134 MET A 274 THR A 365	7WV A 504 (-4.6A) 7WV A 504 (-4.8A) 7WV A 504 (-3.0A) 7WV A 504 ( 3.5A) 7WV A 504 (-3.2A)	0.25A	5u6nB-5u6sA: 67.7	5u6nB-5u6sA: 99.78

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1TT0_C_ACTC6901_0","PYRANOSE OXIDASE","5u6s","UDP-GLYCOSYLTRANSFERASE 74F2","Arabidopsis thaliana",4,"THR A 365;GLN A 134;PHE A 170;PHE A 113","7WV A 504 (-3.2A);7WV A 504 (-3.0A);None;7WV A 504 (-4.8A)","1.46A","1tt0C-5u6sA:2.6",null],["5U6M_A_SALA503_1","UDP-GLYCOSYLTRANSFERASE 74F2","5u6s","UDP-GLYCOSYLTRANSFERASE 74F2","Arabidopsis thaliana",7,"THR A  15;HIS A  18;PHE A 113;GLN A 134;MET A 183;MET A 274;THR A 365","7WV A 504 (-3.7A);7WV A 504 (-4.6A);7WV A 504 (-4.8A);7WV A 504 (-3.0A);None;7WV A 504 ( 3.5A);7WV A 504 (-3.2A)","0.38A","5u6mA-5u6sA:65.4","1tt0C-5u6sA:21.21"],["5U6M_B_SALB503_1","UDP-GLYCOSYLTRANSFERASE 74F2","5u6s","UDP-GLYCOSYLTRANSFERASE 74F2","Arabidopsis thaliana",7,"THR A  15;HIS A  18;PHE A 113;GLN A 134;MET A 183;MET A 274;THR A 365","7WV A 504 (-3.7A);7WV A 504 (-4.6A);7WV A 504 (-4.8A);7WV A 504 (-3.0A);None;7WV A 504 ( 3.5A);7WV A 504 (-3.2A)","0.31A","5u6mB-5u6sA:66.8","5u6mA-5u6sA:100.00"],["5U6N_A_SALA505_1","UDP-GLYCOSYLTRANSFERASE 74F2","5u6s","UDP-GLYCOSYLTRANSFERASE 74F2","Arabidopsis thaliana",7,"HIS A  18;PHE A 113;GLN A 134;MET A 183;MET A 274;TRP A 364;THR A 365","7WV A 504 (-4.6A);7WV A 504 (-4.8A);7WV A 504 (-3.0A);None;7WV A 504 ( 3.5A);BGC A 501 (-4.2A);7WV A 504 (-3.2A)","0.31A","5u6nA-5u6sA:66.1","5u6mB-5u6sA:100.00"],["5U6N_B_SALB504_1","UDP-GLYCOSYLTRANSFERASE 74F2","5u6s","UDP-GLYCOSYLTRANSFERASE 74F2","Arabidopsis thaliana",5,"HIS A  18;PHE A 113;GLN A 134;MET A 274;THR A 365","7WV A 504 (-4.6A);7WV A 504 (-4.8A);7WV A 504 (-3.0A);7WV A 504 ( 3.5A);7WV A 504 (-3.2A)","0.25A","5u6nB-5u6sA:67.7","5u6nA-5u6sA:99.78"]]