SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '7VD'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KW2_A_ADNA300_1 (PROBABLE R-RNA METHYLTRANSFERASE)	5u5g	6-PHOSPHOGLUCONATE DEHYDROGENASE (Pseudomonas syringae)	5 / 11	ILE A 17 GLY A 14 SER A 124 LEU A 135 ALA A 130	None None 7VD A 302 (-2.7A) None None	1.05A	3kw2A-5u5gA: 3.4	3kw2A-5u5gA: 22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KW2_B_ADNB300_1 (PROBABLE R-RNA METHYLTRANSFERASE)	5u5g	6-PHOSPHOGLUCONATE DEHYDROGENASE (Pseudomonas syringae)	5 / 11	ILE A 17 GLY A 14 SER A 124 LEU A 135 ALA A 130	None None 7VD A 302 (-2.7A) None None	1.07A	3kw2B-5u5gA: 3.2	3kw2B-5u5gA: 22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4F5Z_A_BEZA302_0 (HALOALKANE DEHALOGENASE)	5u5g	6-PHOSPHOGLUCONATE DEHYDROGENASE (Pseudomonas syringae)	4 / 8	ASN A 177 VAL A 234 LEU A 243 TYR A 217	7VD A 302 (-3.3A) NAP A 301 (-4.1A) None 7VD A 302 (-4.4A)	1.09A	4f5zA-5u5gA: undetectable	4f5zA-5u5gA: 22.32