SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '7TA'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2E5D_A_NCAA1501_0 (NICOTINAMIDE PHOSPHORIBOSYLTRANSF ERASE)	5u2n	NICOTINAMIDE PHOSPHORIBOSYLTRANSF ERASE (Homo sapiens)	5 / 7	PHE A 193 ARG A 196 ASP A 219 ALA A 244 ARG A 311	7TA A 504 (-3.6A) SO4 A 501 ( 3.2A) 7TA A 504 (-3.3A) 7TA A 504 (-3.5A) SO4 A 501 ( 3.2A)	0.29A	2e5dA-5u2nA: 58.8 2e5dB-5u2nA: 58.6	2e5dA-5u2nA: 100.00 2e5dB-5u2nA: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2E5D_B_NCAB1502_0 (NICOTINAMIDE PHOSPHORIBOSYLTRANSF ERASE)	5u2n	NICOTINAMIDE PHOSPHORIBOSYLTRANSF ERASE (Homo sapiens)	5 / 7	PHE A 193 ARG A 196 ASP A 219 ALA A 244 ARG A 311	7TA A 504 (-3.6A) SO4 A 501 ( 3.2A) 7TA A 504 (-3.3A) 7TA A 504 (-3.5A) SO4 A 501 ( 3.2A)	0.19A	2e5dA-5u2nA: 58.8 2e5dB-5u2nA: 58.6	2e5dA-5u2nA: 100.00 2e5dB-5u2nA: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4LV9_A_20JA601_1 (NICOTINAMIDE PHOSPHORIBOSYLTRANSF ERASE)	5u2n	NICOTINAMIDE PHOSPHORIBOSYLTRANSF ERASE (Homo sapiens)	7 / 8	PHE A 193 ARG A 196 ASP A 219 SER A 241 ALA A 244 SER A 275 ARG A 311	7TA A 504 (-3.6A) SO4 A 501 ( 3.2A) 7TA A 504 (-3.3A) 7TA A 504 ( 3.8A) 7TA A 504 (-3.5A) 7TA A 504 (-2.7A) SO4 A 501 ( 3.2A)	0.24A	4lv9A-5u2nA: 58.7 4lv9B-5u2nA: 58.1	4lv9A-5u2nA: 100.00 4lv9B-5u2nA: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4LV9_B_20JB601_1 (NICOTINAMIDE PHOSPHORIBOSYLTRANSF ERASE)	5u2n	NICOTINAMIDE PHOSPHORIBOSYLTRANSF ERASE (Homo sapiens)	6 / 7	PHE A 193 ASP A 219 SER A 241 ALA A 244 SER A 275 ARG A 311	7TA A 504 (-3.6A) 7TA A 504 (-3.3A) 7TA A 504 ( 3.8A) 7TA A 504 (-3.5A) 7TA A 504 (-2.7A) SO4 A 501 ( 3.2A)	0.23A	4lv9A-5u2nA: 58.7 4lv9B-5u2nA: 58.1	4lv9A-5u2nA: 100.00 4lv9B-5u2nA: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4LV9_B_20JB602_1 (NICOTINAMIDE PHOSPHORIBOSYLTRANSF ERASE)	5u2n	NICOTINAMIDE PHOSPHORIBOSYLTRANSF ERASE (Homo sapiens)	7 / 7	TYR A 188 HIS A 191 VAL A 242 ILE A 309 ARG A 349 ILE A 351 ALA A 379	None 7TA A 504 (-3.6A) 7TA A 504 (-4.3A) 7TA A 504 (-4.4A) None 7TA A 504 (-4.1A) 7TA A 504 (-3.7A)	0.21A	4lv9B-5u2nA: 58.1	4lv9B-5u2nA: 100.00

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2E5D_A_NCAA1501_0","NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE","5u2n","NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE","Homo sapiens",5,"PHE A 193;ARG A 196;ASP A 219;ALA A 244;ARG A 311","7TA A 504 (-3.6A);SO4 A 501 ( 3.2A);7TA A 504 (-3.3A);7TA A 504 (-3.5A);SO4 A 501 ( 3.2A)","0.29A","2e5dA-5u2nA:58.8;2e5dB-5u2nA:58.6",null],["2E5D_B_NCAB1502_0","NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE","5u2n","NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE","Homo sapiens",5,"PHE A 193;ARG A 196;ASP A 219;ALA A 244;ARG A 311","7TA A 504 (-3.6A);SO4 A 501 ( 3.2A);7TA A 504 (-3.3A);7TA A 504 (-3.5A);SO4 A 501 ( 3.2A)","0.19A","2e5dA-5u2nA:58.8;2e5dB-5u2nA:58.6","2e5dA-5u2nA:100.00;2e5dB-5u2nA:100.00"],["4LV9_A_20JA601_1","NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE;NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE","5u2n","NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE","Homo sapiens",7,"PHE A 193;ARG A 196;ASP A 219;SER A 241;ALA A 244;SER A 275;ARG A 311","7TA A 504 (-3.6A);SO4 A 501 ( 3.2A);7TA A 504 (-3.3A);7TA A 504 ( 3.8A);7TA A 504 (-3.5A);7TA A 504 (-2.7A);SO4 A 501 ( 3.2A)","0.24A","4lv9A-5u2nA:58.7;4lv9B-5u2nA:58.1","2e5dA-5u2nA:100.00;2e5dB-5u2nA:100.00"],["4LV9_B_20JB601_1","NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE;NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE","5u2n","NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE","Homo sapiens",6,"PHE A 193;ASP A 219;SER A 241;ALA A 244;SER A 275;ARG A 311","7TA A 504 (-3.6A);7TA A 504 (-3.3A);7TA A 504 ( 3.8A);7TA A 504 (-3.5A);7TA A 504 (-2.7A);SO4 A 501 ( 3.2A)","0.23A","4lv9A-5u2nA:58.7;4lv9B-5u2nA:58.1","4lv9A-5u2nA:100.00;4lv9B-5u2nA:100.00"],["4LV9_B_20JB602_1","NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE","5u2n","NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE","Homo sapiens",7,"TYR A 188;HIS A 191;VAL A 242;ILE A 309;ARG A 349;ILE A 351;ALA A 379","None;7TA A 504 (-3.6A);7TA A 504 (-4.3A);7TA A 504 (-4.4A);None;7TA A 504 (-4.1A);7TA A 504 (-3.7A)","0.21A","4lv9B-5u2nA:58.1","4lv9A-5u2nA:100.00;4lv9B-5u2nA:100.00"]]