SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '7SG'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QAB_F_RTLF2_0
(PROTEIN (RETINOL
BINDING PROTEIN))		 5u24 PUTATIVE
AMINOTRANSFERASE
(Campylobacter
jejuni) 		5 / 12 PHE A  39
ALA A 192
LEU A  32
GLY A  58
HIS A 160
 None
None
None
7SG  A 402 (-3.5A)
None
 1.17A 1qabF-5u24A:
undetectable		 1qabF-5u24A:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_B_SAMB301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 5u24 PUTATIVE
AMINOTRANSFERASE
(Campylobacter
jejuni) 		5 / 12 LEU A  62
GLY A 193
SER A 227
ASN A  57
ALA A 184
 None
None
None
7SG  A 402 (-4.0A)
None
 0.97A 2bm9B-5u24A:
2.3		 2bm9B-5u24A:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XMF_A_HSMA202_1
(NITROPHORIN-7)		 5u24 PUTATIVE
AMINOTRANSFERASE
(Campylobacter
jejuni) 		3 / 3 ASP A 155
LEU A  59
GLY A  58
 7SG  A 402 (-2.6A)
7SG  A 402 (-4.4A)
7SG  A 402 (-3.5A)
 0.48A 4xmfA-5u24A:
undetectable		 4xmfA-5u24A:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_A_SAMA301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 5u24 PUTATIVE
AMINOTRANSFERASE
(Campylobacter
jejuni) 		5 / 12 GLY A  58
ILE A 195
LEU A  64
GLY A  54
GLY A 187
 7SG  A 402 (-3.5A)
None
None
None
None
 1.00A 5d4uA-5u24A:
3.3		 5d4uA-5u24A:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_B_SAMB301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 5u24 PUTATIVE
AMINOTRANSFERASE
(Campylobacter
jejuni) 		5 / 12 GLY A  58
ILE A 195
LEU A  64
GLY A  54
GLY A 187
 7SG  A 402 (-3.5A)
None
None
None
None
 1.07A 5d4uB-5u24A:
2.9		 5d4uB-5u24A:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_D_SAMD301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 5u24 PUTATIVE
AMINOTRANSFERASE
(Campylobacter
jejuni) 		5 / 12 GLY A  58
ILE A 195
LEU A  64
GLY A  54
GLY A 187
 7SG  A 402 (-3.5A)
None
None
None
None
 1.02A 5d4uD-5u24A:
undetectable		 5d4uD-5u24A:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ICX_E_SC2E1_1
(CETUXIMAB FAB LIGHT
CHAIN
MEDITOPE)		 5u24 PUTATIVE
AMINOTRANSFERASE
(Campylobacter
jejuni) 		3 / 3 VAL A 169
GLN A 158
CYH A 156
 None
7SG  A 402 (-3.7A)
None
 0.84A 5icxA-5u24A:
undetectable
5icxE-5u24A:
undetectable		 5icxA-5u24A:
20.48
5icxE-5u24A:
4.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L0Z_A_SAMA304_0
(PROBABLE RNA
METHYLTRANSFERASE,
TRMH FAMILY)		 5u24 PUTATIVE
AMINOTRANSFERASE
(Campylobacter
jejuni) 		5 / 12 THR A  83
ILE A  85
LEU A  89
LEU A  62
ALA A  86
 None
None
None
None
7SG  A 402 ( 3.7A)
 0.98A 5l0zA-5u24A:
undetectable		 5l0zA-5u24A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L0Z_B_SAMB304_0
(PROBABLE RNA
METHYLTRANSFERASE,
TRMH FAMILY)		 5u24 PUTATIVE
AMINOTRANSFERASE
(Campylobacter
jejuni) 		5 / 10 THR A  83
ILE A  85
LEU A  89
LEU A  62
ALA A  86
 None
None
None
None
7SG  A 402 ( 3.7A)
 1.03A 5l0zB-5u24A:
undetectable		 5l0zB-5u24A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M54_B_TA1B502_1
(TUBULIN BETA-2B
CHAIN)		 5u24 PUTATIVE
AMINOTRANSFERASE
(Campylobacter
jejuni) 		5 / 12 HIS A 279
ALA A 184
SER A 179
THR A 342
LEU A   6
 None
None
7SG  A 402 (-2.7A)
None
7SG  A 402 (-4.0A)
 1.45A 5m54B-5u24A:
undetectable		 5m54B-5u24A:
19.56