SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '7OS'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2CBR_A_A80A201_1 (PROTEIN (CRABP-I))	5tzy	FREE FATTY ACID RECEPTOR 1,ENDOLYSIN,FREE FATTY ACID RECEPTOR 1 (Escherichia virus T4; Homo sapiens)	5 / 12	VAL A 134 LEU A 190 GLY A 93 LEU A 59 TYR A 12	7OS A2403 (-4.6A) 7OS A2403 (-4.3A) None None None	1.14A	2cbrA-5tzyA: undetectable	2cbrA-5tzyA: 15.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DF3_A_SAMA301_0 (FIBRILLARIN-LIKE RRNA/TRNA 2'-O-METHYLTRANSFERA SE)	5tzy	FREE FATTY ACID RECEPTOR 1,ENDOLYSIN,FREE FATTY ACID RECEPTOR 1 (Homo sapiens; Escherichia virus T4)	5 / 12	PHE A 96 ALA A 92 VAL A 134 ALA A 99 VAL A 126	None None 7OS A2403 (-4.6A) 7OS A2403 (-3.3A) None	1.21A	4df3A-5tzyA: undetectable	4df3A-5tzyA: 19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4I1R_A_LZUA801_1 (MUCOSA-ASSOCIATED LYMPHOID TISSUE LYMPHOMA TRANSLOCATION PROTEIN 1)	5tzy	FREE FATTY ACID RECEPTOR 1,ENDOLYSIN,FREE FATTY ACID RECEPTOR 1 (Escherichia virus T4; Homo sapiens)	5 / 12	VAL A 134 ALA A 85 PHE A 88 LEU A 90 LEU A 171	7OS A2403 (-4.6A) None None None MK6 A2402 (-4.7A)	1.09A	4i1rA-5tzyA: undetectable	4i1rA-5tzyA: 23.41

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2CBR_A_A80A201_1","PROTEIN (CRABP-I)","5tzy","FREE FATTY ACID RECEPTOR 1,ENDOLYSIN,FREE FATTY ACID RECEPTOR 1","Escherichia virus T4;Homo sapiens",5,"VAL A 134;LEU A 190;GLY A  93;LEU A  59;TYR A  12","7OS A2403 (-4.6A);7OS A2403 (-4.3A);None;None;None","1.14A","2cbrA-5tzyA:undetectable",null],["4DF3_A_SAMA301_0","FIBRILLARIN-LIKE RRNA\/TRNA 2'-O-METHYLTRANSFERASE","5tzy","FREE FATTY ACID RECEPTOR 1,ENDOLYSIN,FREE FATTY ACID RECEPTOR 1","Homo sapiens;Escherichia virus T4",5,"PHE A  96;ALA A  92;VAL A 134;ALA A  99;VAL A 126","None;None;7OS A2403 (-4.6A);7OS A2403 (-3.3A);None","1.21A","4df3A-5tzyA:undetectable","2cbrA-5tzyA:15.06"],["4I1R_A_LZUA801_1","MUCOSA-ASSOCIATED LYMPHOID TISSUE LYMPHOMA TRANSLOCATION PROTEIN 1","5tzy","FREE FATTY ACID RECEPTOR 1,ENDOLYSIN,FREE FATTY ACID RECEPTOR 1","Escherichia virus T4;Homo sapiens",5,"VAL A 134;ALA A  85;PHE A  88;LEU A  90;LEU A 171","7OS A2403 (-4.6A);None;None;None;MK6 A2402 (-4.7A)","1.09A","4i1rA-5tzyA:undetectable","4df3A-5tzyA:19.83"]]