SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '7LV'
DrReposER ID / Desc. | Hit PDBID |
Hit Macromolecule |
Res. Matches |
Interface | HETATM | RMSD | Dali Z-score |
Seq. Identity (%) |
View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1MUO_A_ADNA1_1 (AURORA-RELATEDKINASE 1) |
5tvt | MATERNAL EMBRYONICLEUCINE ZIPPERKINASE (Homosapiens) | 5 / 9 | GLY A 18VAL A 25ALA A 38TYR A 88LEU A 139 | 7LV A 401 ( 3.9A)7LV A 401 ( 4.6A)7LV A 401 (-3.4A)7LV A 401 (-4.6A)7LV A 401 (-4.9A) | 0.49A | 1muoA-5tvtA:11.3 | 1muoA-5tvtA:28.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1T46_A_STIA3_1 (HOMO SAPIENS V-KITHARDY-ZUCKERMAN 4FELINE SARCOMA VIRALONCOGENE HOMOLOG) |
5tvt | MATERNAL EMBRYONICLEUCINE ZIPPERKINASE (Homosapiens) | 8 / 12 | VAL A 25ALA A 38LYS A 40GLU A 57LEU A 61GLY A 92LEU A 139ASP A 150 | 7LV A 401 ( 4.6A)7LV A 401 (-3.4A)7LV A 401 (-3.0A)7LV A 401 (-3.5A)NoneNone7LV A 401 (-4.9A)7LV A 401 (-4.2A) | 1.01A | 1t46A-5tvtA:22.2 | 1t46A-5tvtA:24.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1UWH_A_BAXA1723_1 (B-RAF PROTO-ONCOGENESERINE/THREONINE-PROTEIN KINASE) |
5tvt | MATERNAL EMBRYONICLEUCINE ZIPPERKINASE (Homosapiens) | 5 / 12 | ALA A 38GLU A 57LEU A 61CYH A 89HIS A 130 | 7LV A 401 (-3.4A)7LV A 401 (-3.5A)None7LV A 401 (-4.3A)None | 0.69A | 1uwhA-5tvtA:23.7 | 1uwhA-5tvtA:26.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1UWH_B_BAXB1723_1 (B-RAF PROTO-ONCOGENESERINE/THREONINE-PROTEIN KINASE) |
5tvt | MATERNAL EMBRYONICLEUCINE ZIPPERKINASE (Homosapiens) | 6 / 12 | ALA A 38LYS A 40GLU A 57LEU A 61CYH A 89HIS A 130 | 7LV A 401 (-3.4A)7LV A 401 (-3.0A)7LV A 401 (-3.5A)None7LV A 401 (-4.3A)None | 0.71A | 1uwhB-5tvtA:23.6 | 1uwhB-5tvtA:26.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1UWJ_A_BAXA1723_2 (B-RAF PROTO-ONCOGENESERINE/THREONINE-PROTEIN KINASE) |
5tvt | MATERNAL EMBRYONICLEUCINE ZIPPERKINASE (Homosapiens) | 4 / 7 | ILE A 17LEU A 61ILE A 69ASP A 150 | 7LV A 401 (-4.3A)NoneNone7LV A 401 (-4.2A) | 0.89A | 1uwjA-5tvtA:7.3 | 1uwjA-5tvtA:26.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1UWJ_A_BAXA1723_2 (B-RAF PROTO-ONCOGENESERINE/THREONINE-PROTEIN KINASE) |
5tvt | MATERNAL EMBRYONICLEUCINE ZIPPERKINASE (Homosapiens) | 4 / 7 | ILE A 17LYS A 40LEU A 61ILE A 69 | 7LV A 401 (-4.3A)7LV A 401 (-3.0A)NoneNone | 0.75A | 1uwjA-5tvtA:7.3 | 1uwjA-5tvtA:26.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2EVA_A_ADNA498_1 (TAK1 KINASE - TAB1CHIMERA FUSIONPROTEIN) |
5tvt | MATERNAL EMBRYONICLEUCINE ZIPPERKINASE (Homosapiens) | 6 / 11 | GLY A 18GLY A 20VAL A 25ALA A 38TYR A 88LEU A 139 | 7LV A 401 ( 3.9A)7LV A 401 ( 3.9A)7LV A 401 ( 4.6A)7LV A 401 (-3.4A)7LV A 401 (-4.6A)7LV A 401 (-4.9A) | 0.64A | 2evaA-5tvtA:23.5 | 2evaA-5tvtA:28.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2WGJ_A_VGHA2346_1 (HEPATOCYTE GROWTHFACTOR RECEPTOR) |
5tvt | MATERNAL EMBRYONICLEUCINE ZIPPERKINASE (Homosapiens) | 6 / 12 | GLY A 18VAL A 25ALA A 38LEU A 86TYR A 88ASP A 150 | 7LV A 401 ( 3.9A)7LV A 401 ( 4.6A)7LV A 401 (-3.4A)7LV A 401 ( 4.2A)7LV A 401 (-4.6A)7LV A 401 (-4.2A) | 0.52A | 2wgjA-5tvtA:22.6 | 2wgjA-5tvtA:23.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2Y6O_A_1N1A1892_1 (EPHRIN TYPE-ARECEPTOR 4) |
5tvt | MATERNAL EMBRYONICLEUCINE ZIPPERKINASE (Homosapiens) | 7 / 12 | ILE A 17ALA A 38LYS A 40GLU A 57TYR A 88GLY A 92LEU A 139 | 7LV A 401 (-4.3A)7LV A 401 (-3.4A)7LV A 401 (-3.0A)7LV A 401 (-3.5A)7LV A 401 (-4.6A)None7LV A 401 (-4.9A) | 0.85A | 2y6oA-5tvtA:23.1 | 2y6oA-5tvtA:26.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3G0E_A_B49A9000_1 (MAST/STEM CELLGROWTH FACTORRECEPTOR) |
5tvt | MATERNAL EMBRYONICLEUCINE ZIPPERKINASE (Homosapiens) | 6 / 11 | VAL A 25ALA A 38TYR A 88CYH A 89GLY A 92LEU A 139 | 7LV A 401 ( 4.6A)7LV A 401 (-3.4A)7LV A 401 (-4.6A)7LV A 401 (-4.3A)None7LV A 401 (-4.9A) | 0.40A | 3g0eA-5tvtA:21.4 | 3g0eA-5tvtA:23.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3G0F_A_B49A9001_1 (MAST/STEM CELLGROWTH FACTORRECEPTOR) |
5tvt | MATERNAL EMBRYONICLEUCINE ZIPPERKINASE (Homosapiens) | 6 / 11 | VAL A 25ALA A 38TYR A 88CYH A 89GLY A 92LEU A 139 | 7LV A 401 ( 4.6A)7LV A 401 (-3.4A)7LV A 401 (-4.6A)7LV A 401 (-4.3A)None7LV A 401 (-4.9A) | 0.39A | 3g0fA-5tvtA:22.4 | 3g0fA-5tvtA:23.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3G0F_B_B49B9001_1 (MAST/STEM CELLGROWTH FACTORRECEPTOR) |
5tvt | MATERNAL EMBRYONICLEUCINE ZIPPERKINASE (Homosapiens) | 6 / 10 | VAL A 25ALA A 38TYR A 88CYH A 89GLY A 92LEU A 139 | 7LV A 401 ( 4.6A)7LV A 401 (-3.4A)7LV A 401 (-4.6A)7LV A 401 (-4.3A)None7LV A 401 (-4.9A) | 0.43A | 3g0fB-5tvtA:22.4 | 3g0fB-5tvtA:23.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3OG7_A_032A1_1 (AKAP9-BRAF FUSIONPROTEIN) |
5tvt | MATERNAL EMBRYONICLEUCINE ZIPPERKINASE (Homosapiens) | 5 / 12 | VAL A 25ALA A 38LYS A 40CYH A 89PHE A 151 | 7LV A 401 ( 4.6A)7LV A 401 (-3.4A)7LV A 401 (-3.0A)7LV A 401 (-4.3A)None | 0.79A | 3og7A-5tvtA:23.3 | 3og7A-5tvtA:26.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3OHT_B_1N1B1000_1 (P38A) |
5tvt | MATERNAL EMBRYONICLEUCINE ZIPPERKINASE (Homosapiens) | 5 / 12 | GLY A 18VAL A 25ALA A 38LYS A 40LEU A 61 | 7LV A 401 ( 3.9A)7LV A 401 ( 4.6A)7LV A 401 (-3.4A)7LV A 401 (-3.0A)None | 0.52A | 3ohtB-5tvtA:6.4 | 3ohtB-5tvtA:23.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4BKJ_A_STIA1000_1 (EPITHELIAL DISCOIDINDOMAIN-CONTAININGRECEPTOR 1) |
5tvt | MATERNAL EMBRYONICLEUCINE ZIPPERKINASE (Homosapiens) | 7 / 12 | VAL A 25ALA A 38GLU A 57MET A 84TYR A 88LEU A 139ASP A 150 | 7LV A 401 ( 4.6A)7LV A 401 (-3.4A)7LV A 401 (-3.5A)None7LV A 401 (-4.6A)7LV A 401 (-4.9A)7LV A 401 (-4.2A) | 1.22A | 4bkjA-5tvtA:22.0 | 4bkjA-5tvtA:23.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4I41_A_MIXA500_1 (SERINE/THREONINE-PROTEIN KINASE PIM-1) |
5tvt | MATERNAL EMBRYONICLEUCINE ZIPPERKINASE (Homosapiens) | 9 / 12 | VAL A 25ALA A 38ASP A 96ASP A 132LYS A 134ASN A 137LEU A 139ILE A 149ASP A 150 | 7LV A 401 ( 4.6A)7LV A 401 (-3.4A)NoneNoneNoneNone7LV A 401 (-4.9A)7LV A 401 (-3.6A)7LV A 401 (-4.2A) | 0.77A | 4i41A-5tvtA:27.7 | 4i41A-5tvtA:29.48 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4IAA_A_RTZA401_1 (SERINE/THREONINE-PROTEIN KINASE PIM-1) |
5tvt | MATERNAL EMBRYONICLEUCINE ZIPPERKINASE (Homosapiens) | 6 / 11 | ALA A 38LEU A 86GLU A 136LEU A 139ILE A 149ASP A 150 | 7LV A 401 (-3.4A)7LV A 401 ( 4.2A)None7LV A 401 (-4.9A)7LV A 401 (-3.6A)7LV A 401 (-4.2A) | 1.16A | 4iaaA-5tvtA:27.7 | 4iaaA-5tvtA:30.06 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4IAA_A_RTZA401_1 (SERINE/THREONINE-PROTEIN KINASE PIM-1) |
5tvt | MATERNAL EMBRYONICLEUCINE ZIPPERKINASE (Homosapiens) | 7 / 11 | VAL A 25ALA A 38LYS A 40LEU A 86LEU A 139ILE A 149ASP A 150 | 7LV A 401 ( 4.6A)7LV A 401 (-3.4A)7LV A 401 (-3.0A)7LV A 401 ( 4.2A)7LV A 401 (-4.9A)7LV A 401 (-3.6A)7LV A 401 (-4.2A) | 0.64A | 4iaaA-5tvtA:27.7 | 4iaaA-5tvtA:30.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4IFG_A_1E8A601_1 (CALMODULIN-DOMAINPROTEIN KINASE 1) |
5tvt | MATERNAL EMBRYONICLEUCINE ZIPPERKINASE (Homosapiens) | 8 / 12 | GLY A 18VAL A 25ALA A 38LEU A 72GLY A 92GLU A 93LEU A 139ILE A 149 | 7LV A 401 ( 3.9A)7LV A 401 ( 4.6A)7LV A 401 (-3.4A)NoneNone7LV A 401 ( 4.7A)7LV A 401 (-4.9A)7LV A 401 (-3.6A) | 0.38A | 4ifgA-5tvtA:24.4 | 4ifgA-5tvtA:25.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4QMN_A_DB8A401_1 (SERINE/THREONINE-PROTEIN KINASE 24) |
5tvt | MATERNAL EMBRYONICLEUCINE ZIPPERKINASE (Homosapiens) | 7 / 12 | ILE A 17ALA A 38LYS A 40GLU A 57TYR A 88LEU A 139ASP A 150 | 7LV A 401 (-4.3A)7LV A 401 (-3.4A)7LV A 401 (-3.0A)7LV A 401 (-3.5A)7LV A 401 (-4.6A)7LV A 401 (-4.9A)7LV A 401 (-4.2A) | 0.74A | 4qmnA-5tvtA:28.3 | 4qmnA-5tvtA:26.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4QMS_A_1N1A401_1 (SERINE/THREONINE-PROTEIN KINASE 24) |
5tvt | MATERNAL EMBRYONICLEUCINE ZIPPERKINASE (Homosapiens) | 7 / 11 | ILE A 17ALA A 38LYS A 40GLU A 57TYR A 88LEU A 139ASP A 150 | 7LV A 401 (-4.3A)7LV A 401 (-3.4A)7LV A 401 (-3.0A)7LV A 401 (-3.5A)7LV A 401 (-4.6A)7LV A 401 (-4.9A)7LV A 401 (-4.2A) | 0.83A | 4qmsA-5tvtA:28.3 | 4qmsA-5tvtA:26.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4QMZ_A_B49A401_1 (SERINE/THREONINE-PROTEIN KINASE 24) |
5tvt | MATERNAL EMBRYONICLEUCINE ZIPPERKINASE (Homosapiens) | 6 / 12 | ILE A 17GLY A 18VAL A 25ALA A 38TYR A 88LEU A 139 | 7LV A 401 (-4.3A)7LV A 401 ( 3.9A)7LV A 401 ( 4.6A)7LV A 401 (-3.4A)7LV A 401 (-4.6A)7LV A 401 (-4.9A) | 0.39A | 4qmzA-5tvtA:28.4 | 4qmzA-5tvtA:26.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4R7I_A_STIA1001_1 (MACROPHAGECOLONY-STIMULATINGFACTOR 1 RECEPTOR) |
5tvt | MATERNAL EMBRYONICLEUCINE ZIPPERKINASE (Homosapiens) | 7 / 12 | VAL A 25ALA A 38LYS A 40GLU A 57CYH A 89LEU A 139ASP A 150 | 7LV A 401 ( 4.6A)7LV A 401 (-3.4A)7LV A 401 (-3.0A)7LV A 401 (-3.5A)7LV A 401 (-4.3A)7LV A 401 (-4.9A)7LV A 401 (-4.2A) | 0.92A | 4r7iA-5tvtA:21.9 | 4r7iA-5tvtA:26.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4U0I_A_0LIA1001_2 (MAST/STEM CELLGROWTH FACTORRECEPTORKIT,MAST/STEM CELLGROWTH FACTORRECEPTOR KIT) |
5tvt | MATERNAL EMBRYONICLEUCINE ZIPPERKINASE (Homosapiens) | 7 / 12 | ALA A 38LYS A 40LEU A 61CYH A 89GLY A 92HIS A 130LEU A 139 | 7LV A 401 (-3.4A)7LV A 401 (-3.0A)None7LV A 401 (-4.3A)NoneNone7LV A 401 (-4.9A) | 0.74A | 4u0iA-5tvtA:22.2 | 4u0iA-5tvtA:24.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4U0I_A_0LIA1001_2 (MAST/STEM CELLGROWTH FACTORRECEPTORKIT,MAST/STEM CELLGROWTH FACTORRECEPTOR KIT) |
5tvt | MATERNAL EMBRYONICLEUCINE ZIPPERKINASE (Homosapiens) | 7 / 12 | ALA A 38LYS A 40LEU A 61CYH A 89GLY A 92LEU A 139ASP A 150 | 7LV A 401 (-3.4A)7LV A 401 (-3.0A)None7LV A 401 (-4.3A)None7LV A 401 (-4.9A)7LV A 401 (-4.2A) | 0.86A | 4u0iA-5tvtA:22.2 | 4u0iA-5tvtA:24.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4U5J_A_RXTA601_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE SRC) |
5tvt | MATERNAL EMBRYONICLEUCINE ZIPPERKINASE (Homosapiens) | 8 / 11 | GLY A 20VAL A 25ALA A 38TYR A 88GLY A 92ASN A 137LEU A 139ASP A 150 | 7LV A 401 ( 3.9A)7LV A 401 ( 4.6A)7LV A 401 (-3.4A)7LV A 401 (-4.6A)NoneNone7LV A 401 (-4.9A)7LV A 401 (-4.2A) | 0.73A | 4u5jA-5tvtA:19.4 | 4u5jA-5tvtA:26.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4XV2_A_P06A801_1 (SERINE/THREONINE-PROTEIN KINASE B-RAF) |
5tvt | MATERNAL EMBRYONICLEUCINE ZIPPERKINASE (Homosapiens) | 6 / 12 | VAL A 25ALA A 38LYS A 40CYH A 89ASP A 150PHE A 151 | 7LV A 401 ( 4.6A)7LV A 401 (-3.4A)7LV A 401 (-3.0A)7LV A 401 (-4.3A)7LV A 401 (-4.2A)None | 0.91A | 4xv2A-5tvtA:23.0 | 4xv2A-5tvtA:27.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4XV2_B_P06B801_1 (SERINE/THREONINE-PROTEIN KINASE B-RAF) |
5tvt | MATERNAL EMBRYONICLEUCINE ZIPPERKINASE (Homosapiens) | 5 / 12 | ALA A 38LYS A 40CYH A 89ASP A 150PHE A 151 | 7LV A 401 (-3.4A)7LV A 401 (-3.0A)7LV A 401 (-4.3A)7LV A 401 (-4.2A)None | 0.80A | 4xv2B-5tvtA:23.6 | 4xv2B-5tvtA:27.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5CSW_A_P06A801_1 (SERINE/THREONINE-PROTEIN KINASE B-RAF) |
5tvt | MATERNAL EMBRYONICLEUCINE ZIPPERKINASE (Homosapiens) | 5 / 12 | VAL A 25ALA A 38LYS A 40CYH A 89PHE A 151 | 7LV A 401 ( 4.6A)7LV A 401 (-3.4A)7LV A 401 (-3.0A)7LV A 401 (-4.3A)None | 0.83A | 5cswA-5tvtA:23.1 | 5cswA-5tvtA:27.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5CSW_B_P06B801_1 (SERINE/THREONINE-PROTEIN KINASE B-RAF) |
5tvt | MATERNAL EMBRYONICLEUCINE ZIPPERKINASE (Homosapiens) | 5 / 12 | VAL A 25ALA A 38LYS A 40CYH A 89PHE A 151 | 7LV A 401 ( 4.6A)7LV A 401 (-3.4A)7LV A 401 (-3.0A)7LV A 401 (-4.3A)None | 0.82A | 5cswB-5tvtA:22.9 | 5cswB-5tvtA:27.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5HI2_A_BAXA801_1 (SERINE/THREONINE-PROTEIN KINASE B-RAF) |
5tvt | MATERNAL EMBRYONICLEUCINE ZIPPERKINASE (Homosapiens) | 6 / 12 | ALA A 38LYS A 40GLU A 57LEU A 61CYH A 89HIS A 130 | 7LV A 401 (-3.4A)7LV A 401 (-3.0A)7LV A 401 (-3.5A)None7LV A 401 (-4.3A)None | 0.73A | 5hi2A-5tvtA:23.6 | 5hi2A-5tvtA:27.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5LVN_A_ADNA402_1 (3-PHOSPHOINOSITIDE-DEPENDENT PROTEINKINASE 1) |
5tvt | MATERNAL EMBRYONICLEUCINE ZIPPERKINASE (Homosapiens) | 7 / 11 | GLY A 18VAL A 25ALA A 38LEU A 86TYR A 88GLU A 93LEU A 139 | 7LV A 401 ( 3.9A)7LV A 401 ( 4.6A)7LV A 401 (-3.4A)7LV A 401 ( 4.2A)7LV A 401 (-4.6A)7LV A 401 ( 4.7A)7LV A 401 (-4.9A) | 0.30A | 5lvnA-5tvtA:30.4 | 5lvnA-5tvtA:28.61 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5MAF_A_XINA403_2 (MATERNAL EMBRYONICLEUCINE ZIPPERKINASE) |
5tvt | MATERNAL EMBRYONICLEUCINE ZIPPERKINASE (Homosapiens) | 4 / 5 | LEU A 61CYH A 70CYH A 89ASP A 150 | None7LV A 401 ( 3.7A)7LV A 401 (-4.3A)7LV A 401 (-4.2A) | 0.72A | 5mafA-5tvtA:45.6 | 5mafA-5tvtA:98.75 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5MAF_A_XINA403_2 (MATERNAL EMBRYONICLEUCINE ZIPPERKINASE) |
5tvt | MATERNAL EMBRYONICLEUCINE ZIPPERKINASE (Homosapiens) | 4 / 5 | LEU A 61CYH A 70CYH A 89LEU A 139 | None7LV A 401 ( 3.7A)7LV A 401 (-4.3A)7LV A 401 (-4.9A) | 0.19A | 5mafA-5tvtA:45.6 | 5mafA-5tvtA:98.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5OWR_A_1N1A401_1 (SERINE/THREONINE-PROTEIN KINASE 10) |
5tvt | MATERNAL EMBRYONICLEUCINE ZIPPERKINASE (Homosapiens) | 5 / 8 | ALA A 38GLU A 57CYH A 89LEU A 139ASP A 150 | 7LV A 401 (-3.4A)7LV A 401 (-3.5A)7LV A 401 (-4.3A)7LV A 401 (-4.9A)7LV A 401 (-4.2A) | 0.63A | 5owrA-5tvtA:22.3 | 5owrA-5tvtA:28.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5VC3_A_DB8A601_1 (WEE1-LIKE PROTEINKINASE) |
5tvt | MATERNAL EMBRYONICLEUCINE ZIPPERKINASE (Homosapiens) | 8 / 12 | GLU A 15ILE A 17GLY A 18ALA A 38GLU A 57TYR A 88CYH A 89ASP A 150 | None7LV A 401 (-4.3A)7LV A 401 ( 3.9A)7LV A 401 (-3.4A)7LV A 401 (-3.5A)7LV A 401 (-4.6A)7LV A 401 (-4.3A)7LV A 401 (-4.2A) | 0.92A | 5vc3A-5tvtA:25.9 | 5vc3A-5tvtA:24.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5VC3_A_DB8A601_1 (WEE1-LIKE PROTEINKINASE) |
5tvt | MATERNAL EMBRYONICLEUCINE ZIPPERKINASE (Homosapiens) | 7 / 12 | ILE A 17GLY A 18GLU A 57TYR A 88CYH A 89GLY A 92ASP A 150 | 7LV A 401 (-4.3A)7LV A 401 ( 3.9A)7LV A 401 (-3.5A)7LV A 401 (-4.6A)7LV A 401 (-4.3A)None7LV A 401 (-4.2A) | 0.88A | 5vc3A-5tvtA:25.9 | 5vc3A-5tvtA:24.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5Y7Z_B_IREB401_0 (CYCLIN-G-ASSOCIATEDKINASE) |
5tvt | MATERNAL EMBRYONICLEUCINE ZIPPERKINASE (Homosapiens) | 7 / 12 | ALA A 38LYS A 40GLU A 57CYH A 89GLY A 92LEU A 139ASP A 150 | 7LV A 401 (-3.4A)7LV A 401 (-3.0A)7LV A 401 (-3.5A)7LV A 401 (-4.3A)None7LV A 401 (-4.9A)7LV A 401 (-4.2A) | 0.85A | 5y7zB-5tvtA:25.4 | 5y7zB-5tvtA:16.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5Y80_A_IREA401_0 (CYCLIN-G-ASSOCIATEDKINASE) |
5tvt | MATERNAL EMBRYONICLEUCINE ZIPPERKINASE (Homosapiens) | 8 / 12 | VAL A 25ALA A 38LYS A 40GLU A 57CYH A 89GLY A 92LEU A 139ASP A 150 | 7LV A 401 ( 4.6A)7LV A 401 (-3.4A)7LV A 401 (-3.0A)7LV A 401 (-3.5A)7LV A 401 (-4.3A)None7LV A 401 (-4.9A)7LV A 401 (-4.2A) | 0.75A | 5y80A-5tvtA:25.0 | 5y80A-5tvtA:16.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5Y9M_X_NIOX401_1 (CASEIN KINASE IISUBUNIT ALPHA') |
5tvt | MATERNAL EMBRYONICLEUCINE ZIPPERKINASE (Homosapiens) | 4 / 8 | VAL A 25LYS A 40ILE A 149ASP A 150 | 7LV A 401 ( 4.6A)7LV A 401 (-3.0A)7LV A 401 (-3.6A)7LV A 401 (-4.2A) | 0.59A | 5y9mX-5tvtA:22.8 | 5y9mX-5tvtA:12.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5YF9_B_NIOB401_1 (CASEIN KINASE IISUBUNIT ALPHA') |
5tvt | MATERNAL EMBRYONICLEUCINE ZIPPERKINASE (Homosapiens) | 4 / 7 | VAL A 25LYS A 40ILE A 149ASP A 150 | 7LV A 401 ( 4.6A)7LV A 401 (-3.0A)7LV A 401 (-3.6A)7LV A 401 (-4.2A) | 0.72A | 5yf9B-5tvtA:22.7 | 5yf9B-5tvtA:12.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ZV2_A_LEVA801_2 (FIBROBLAST GROWTHFACTOR RECEPTOR 1) |
5tvt | MATERNAL EMBRYONICLEUCINE ZIPPERKINASE (Homosapiens) | 3 / 3 | LYS A 40LEU A 139ASP A 150 | 7LV A 401 (-3.0A)7LV A 401 (-4.9A)7LV A 401 (-4.2A) | 0.86A | 5zv2A-5tvtA:22.3 | 5zv2A-5tvtA:14.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6BSD_A_1N1A901_0 (EPITHELIAL DISCOIDINDOMAIN-CONTAININGRECEPTOR 1) |
5tvt | MATERNAL EMBRYONICLEUCINE ZIPPERKINASE (Homosapiens) | 8 / 12 | VAL A 25ALA A 38LYS A 40GLU A 57TYR A 88GLY A 92LEU A 139ASP A 150 | 7LV A 401 ( 4.6A)7LV A 401 (-3.4A)7LV A 401 (-3.0A)7LV A 401 (-3.5A)7LV A 401 (-4.6A)None7LV A 401 (-4.9A)7LV A 401 (-4.2A) | 1.39A | 6bsdA-5tvtA:21.9 | 6bsdA-5tvtA:15.54 |