SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '7H8'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PEO_F_CU9F301_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 5m6m E3 UBIQUITIN-PROTEIN
LIGASE XIAP
(Homo
sapiens) 		4 / 7 TRP A 310
TYR A 329
CYH A 327
CYH A 303
 7H8  A 403 (-2.8A)
None
ZN  A 401 (-2.2A)
ZN  A 401 (-2.3A)
 1.15A 3peoF-5m6mA:
0.0		 3peoF-5m6mA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W7P_A_SAMA501_0
(OXAC)		 5m6m E3 UBIQUITIN-PROTEIN
LIGASE XIAP
(Homo
sapiens) 		5 / 12 GLY A 288
LEU A 307
VAL A 298
ARG A 286
ASP A 315
 None
7H8  A 403 (-3.4A)
7H8  A 403 (-4.8A)
None
None
 1.15A 5w7pA-5m6mA:
undetectable		 5w7pA-5m6mA:
17.35