SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '7H7'


List of Similar Pattern of Amino Acids


Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U5K_A_08JA1_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)
5tpx HISTONE
ACETYLTRANSFERASE
GCN5

(Plasmodium
falciparum)
4 / 8 TRP A1379
PRO A1380
VAL A1385
ASN A1436
None
None
7H7  A1505 (-4.0A)
7H7  A1505 (-3.1A)
0.67A 3u5kA-5tpxA:
15.9
3u5kA-5tpxA:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U5K_B_08JB2_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)
5tpx HISTONE
ACETYLTRANSFERASE
GCN5

(Plasmodium
falciparum)
4 / 7 TRP A1379
PRO A1380
VAL A1385
ASN A1436
None
None
7H7  A1505 (-4.0A)
7H7  A1505 (-3.1A)
0.62A 3u5kB-5tpxA:
15.8
3u5kB-5tpxA:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U5K_C_08JC3_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)
5tpx HISTONE
ACETYLTRANSFERASE
GCN5

(Plasmodium
falciparum)
4 / 8 TRP A1379
PRO A1380
VAL A1385
ASN A1436
None
None
7H7  A1505 (-4.0A)
7H7  A1505 (-3.1A)
0.69A 3u5kC-5tpxA:
15.9
3u5kC-5tpxA:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U5K_D_08JD4_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)
5tpx HISTONE
ACETYLTRANSFERASE
GCN5

(Plasmodium
falciparum)
4 / 8 TRP A1379
PRO A1380
VAL A1385
ASN A1436
None
None
7H7  A1505 (-4.0A)
7H7  A1505 (-3.1A)
0.70A 3u5kD-5tpxA:
15.9
3u5kD-5tpxA:
30.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5PBE_A_TYLA2001_1
(BROMODOMAIN ADJACENT
TO ZINC FINGER
DOMAIN PROTEIN 2B)
5tpx HISTONE
ACETYLTRANSFERASE
GCN5

(Plasmodium
falciparum)
4 / 6 PRO A1380
VAL A1385
TYR A1393
ASN A1436
None
7H7  A1505 (-4.0A)
None
7H7  A1505 (-3.1A)
0.68A 5pbeA-5tpxA:
16.6
5pbeA-5tpxA:
37.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Y1Y_A_HNQA201_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)
5tpx HISTONE
ACETYLTRANSFERASE
GCN5

(Plasmodium
falciparum)
5 / 8 PRO A1380
VAL A1385
CYH A1432
TYR A1435
ASN A1436
None
7H7  A1505 (-4.0A)
7H7  A1505 ( 3.7A)
None
7H7  A1505 (-3.1A)
0.67A 5y1yA-5tpxA:
15.9
5y1yA-5tpxA:
30.95