SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '7DZ'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2UVN_A_ECNA1409_1 (CYTOCHROME P450 130)	5uu1	SERINE/THREONINE-PRO TEIN KINASE VRK2 (Homo sapiens)	5 / 12	LEU A 124 MET A 121 GLY A 38 GLY A 39 LEU A 173	7DZ A 401 (-4.1A) 7DZ A 401 (-4.3A) 7DZ A 401 (-3.3A) None None	0.83A	2uvnA-5uu1A: undetectable	2uvnA-5uu1A: 20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FWD_A_BO2A801_1 (TTC1975 PEPTIDASE)	5uu1	SERINE/THREONINE-PRO TEIN KINASE VRK2 (Homo sapiens)	5 / 9	VAL A 59 VAL A 60 ILE A 35 GLY A 32 ALA A 56	7DZ A 401 (-4.6A) None 7DZ A 401 ( 4.9A) None None	0.94A	4fwdA-5uu1A: undetectable	4fwdA-5uu1A: 17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4OGR_A_ADNA401_1 (CYCLIN-DEPENDENT KINASE 9)	5uu1	SERINE/THREONINE-PRO TEIN KINASE VRK2 (Homo sapiens)	5 / 8	GLY A 39 ASP A 127 ASN A 171 LEU A 173 ASP A 186	None None 7DZ A 401 ( 4.7A) None 7DZ A 401 ( 4.8A)	0.53A	4ogrA-5uu1A: 21.7	4ogrA-5uu1A: 23.68