SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '7DY'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W1B_A_DXCA2034_0
(ACRIFLAVIN
RESISTANCE PROTEIN B)		 5u09 CANNABINOID RECEPTOR
1,GLGA GLYCOGEN
SYNTHASE
(Homo
sapiens;
Pyrococcus
abyssi) 		3 / 3 PHE A 102
SER A 383
LEU A 387
 None
7DY  A1210 (-3.0A)
7DY  A1210 (-4.6A)
 0.79A 2w1bA-5u09A:
undetectable		 2w1bA-5u09A:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9K_A_CAMA424_0
(CYTOCHROME P450)		 5u09 CANNABINOID RECEPTOR
1,GLGA GLYCOGEN
SYNTHASE
(Homo
sapiens;
Pyrococcus
abyssi) 		5 / 9 TRP A 279
THR A 283
LEU A 359
LEU A 360
GLY A 357
 None
None
7DY  A1210 ( 4.9A)
None
None
 1.40A 4c9kA-5u09A:
undetectable		 4c9kA-5u09A:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9K_B_CAMB424_0
(CYTOCHROME P450)		 5u09 CANNABINOID RECEPTOR
1,GLGA GLYCOGEN
SYNTHASE
(Homo
sapiens;
Pyrococcus
abyssi) 		5 / 9 TRP A 279
THR A 283
LEU A 359
LEU A 360
GLY A 357
 None
None
7DY  A1210 ( 4.9A)
None
None
 1.37A 4c9kB-5u09A:
undetectable		 4c9kB-5u09A:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9P_A_CAMA423_0
(CYTOCHROME P450)		 5u09 CANNABINOID RECEPTOR
1,GLGA GLYCOGEN
SYNTHASE
(Homo
sapiens;
Pyrococcus
abyssi) 		5 / 9 TRP A 279
THR A 283
LEU A 359
LEU A 360
GLY A 357
 None
None
7DY  A1210 ( 4.9A)
None
None
 1.40A 4c9pA-5u09A:
undetectable		 4c9pA-5u09A:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9P_A_CAMA423_0
(CYTOCHROME P450)		 5u09 CANNABINOID RECEPTOR
1,GLGA GLYCOGEN
SYNTHASE
(Homo
sapiens;
Pyrococcus
abyssi) 		5 / 9 TRP A 279
THR A 283
LEU A 359
LEU A 360
VAL A 204
 None
None
7DY  A1210 ( 4.9A)
None
None
 1.40A 4c9pA-5u09A:
undetectable		 4c9pA-5u09A:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JVL_A_ESTA702_1
(ESTROGEN
SULFOTRANSFERASE)		 5u09 CANNABINOID RECEPTOR
1,GLGA GLYCOGEN
SYNTHASE
(Homo
sapiens;
Pyrococcus
abyssi) 		4 / 9 CYH A 386
PHE A 268
ILE A 362
MET A 363
 7DY  A1210 (-3.8A)
7DY  A1210 ( 4.7A)
None
None
 1.37A 4jvlA-5u09A:
undetectable		 4jvlA-5u09A:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X3M_A_ADNA301_1
(RNA 2'-O RIBOSE
METHYLTRANSFERASE)		 5u09 CANNABINOID RECEPTOR
1,GLGA GLYCOGEN
SYNTHASE
(Homo
sapiens;
Pyrococcus
abyssi) 		5 / 9 PRO A 394
LEU A 138
GLY A 157
SER A 390
VAL A 161
 SO4  A1209 (-4.7A)
None
None
7DY  A1210 ( 4.1A)
None
 1.45A 4x3mA-5u09A:
4.2		 4x3mA-5u09A:
22.11