SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '7DX'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_2_BO221405_1
(PROTEASOME COMPONENT
PRE3)		 5m2b PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 11 THR K   1
ALA K  28
SER K  46
GLY K  47
ALA K  49
 7DX  K 301 (-3.3A)
7DX  K 301 ( 4.6A)
None
7DX  K 301 (-3.8A)
7DX  K 301 (-3.2A)
 0.84A 2f162-5m2bK:
28.9		 2f162-5m2bK:
29.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_2_BO221405_1
(PROTEASOME COMPONENT
PRE3)		 5m2b PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 11 THR K   1
LYS K  33
SER K  46
GLY K  47
ALA K  49
 7DX  K 301 (-3.3A)
7DX  K 301 (-4.2A)
None
7DX  K 301 (-3.8A)
7DX  K 301 (-3.2A)
 0.32A 2f162-5m2bK:
28.9		 2f162-5m2bK:
29.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_2_BO221405_1
(PROTEASOME COMPONENT
PRE3)		 5m2b PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 11 THR K   2
THR K   1
SER K 173
GLY K 172
ALA K 164
 None
7DX  K 301 (-3.3A)
None
None
MG  K 302 (-4.8A)
 0.97A 2f162-5m2bK:
28.9		 2f162-5m2bK:
29.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_H_BO2H1400_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 5m2b PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 11 THR K   1
ALA K  28
LYS K  33
GLY K  47
ALA K  49
 7DX  K 301 (-3.3A)
7DX  K 301 ( 4.6A)
7DX  K 301 (-4.2A)
7DX  K 301 (-3.8A)
7DX  K 301 (-3.2A)
 1.04A 2f16H-5m2bK:
29.5
2f16I-5m2bK:
25.8		 2f16H-5m2bK:
28.57
2f16I-5m2bK:
23.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2F16_K_BO2K1402_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 5m2b PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		7 / 10 THR K   1
ALA K  20
ALA K  22
VAL K  31
LYS K  33
GLY K  47
ALA K  49
 7DX  K 301 (-3.3A)
7DX  K 301 ( 4.0A)
None
7DX  K 301 (-4.2A)
7DX  K 301 (-4.2A)
7DX  K 301 (-3.8A)
7DX  K 301 (-3.2A)
 0.57A 2f16K-5m2bK:
37.5
2f16L-5m2bK:
24.0		 2f16K-5m2bK:
76.89
2f16L-5m2bK:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_N_BO2N1404_1
(PROTEASOME COMPONENT
PRE3)		 5m2b PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 11 THR K   1
ALA K  28
SER K  46
GLY K  47
ALA K  49
 7DX  K 301 (-3.3A)
7DX  K 301 ( 4.6A)
None
7DX  K 301 (-3.8A)
7DX  K 301 (-3.2A)
 0.83A 2f16N-5m2bK:
29.0		 2f16N-5m2bK:
29.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_N_BO2N1404_1
(PROTEASOME COMPONENT
PRE3)		 5m2b PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 11 THR K   1
LYS K  33
SER K  46
GLY K  47
ALA K  49
 7DX  K 301 (-3.3A)
7DX  K 301 (-4.2A)
None
7DX  K 301 (-3.8A)
7DX  K 301 (-3.2A)
 0.33A 2f16N-5m2bK:
29.0		 2f16N-5m2bK:
29.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_N_BO2N1404_1
(PROTEASOME COMPONENT
PRE3)		 5m2b PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 11 THR K   2
THR K   1
SER K 173
GLY K 172
ALA K 164
 None
7DX  K 301 (-3.3A)
None
None
MG  K 302 (-4.8A)
 0.97A 2f16N-5m2bK:
29.0		 2f16N-5m2bK:
29.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_V_BO2V1401_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 5m2b PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 11 THR K   1
ALA K  28
LYS K  33
GLY K  47
ALA K  49
 7DX  K 301 (-3.3A)
7DX  K 301 ( 4.6A)
7DX  K 301 (-4.2A)
7DX  K 301 (-3.8A)
7DX  K 301 (-3.2A)
 1.04A 2f16V-5m2bK:
29.6
2f16W-5m2bK:
25.8		 2f16V-5m2bK:
28.57
2f16W-5m2bK:
23.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2F16_Y_BO2Y1403_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 5m2b PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		7 / 10 THR K   1
ALA K  20
ALA K  22
VAL K  31
LYS K  33
GLY K  47
ALA K  49
 7DX  K 301 (-3.3A)
7DX  K 301 ( 4.0A)
None
7DX  K 301 (-4.2A)
7DX  K 301 (-4.2A)
7DX  K 301 (-3.8A)
7DX  K 301 (-3.2A)
 0.57A 2f16Y-5m2bK:
24.8
2f16Z-5m2bK:
23.7		 2f16Y-5m2bK:
76.89
2f16Z-5m2bK:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_2_BO221405_1
(PROTEASOME COMPONENT
PRE3
PROTEASOME COMPONENT
PUP1)		 5m2b PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 12 ALA K  28
SER K  46
GLY K  47
ALA K  49
SER K 170
 7DX  K 301 ( 4.6A)
None
7DX  K 301 (-3.8A)
7DX  K 301 (-3.2A)
None
 1.07A 3mg02-5m2bK:
28.9
3mg0V-5m2bK:
29.7		 3mg02-5m2bK:
29.67
3mg0V-5m2bK:
28.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_2_BO221405_1
(PROTEASOME COMPONENT
PRE3
PROTEASOME COMPONENT
PUP1)		 5m2b PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 12 THR K   1
ALA K  28
SER K  46
GLY K  47
ALA K  49
 7DX  K 301 (-3.3A)
7DX  K 301 ( 4.6A)
None
7DX  K 301 (-3.8A)
7DX  K 301 (-3.2A)
 0.85A 3mg02-5m2bK:
28.9
3mg0V-5m2bK:
29.7		 3mg02-5m2bK:
29.67
3mg0V-5m2bK:
28.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_2_BO221405_1
(PROTEASOME COMPONENT
PRE3
PROTEASOME COMPONENT
PUP1)		 5m2b PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 12 THR K   1
LYS K  33
SER K  46
GLY K  47
ALA K  49
 7DX  K 301 (-3.3A)
7DX  K 301 (-4.2A)
None
7DX  K 301 (-3.8A)
7DX  K 301 (-3.2A)
 0.39A 3mg02-5m2bK:
28.9
3mg0V-5m2bK:
29.7		 3mg02-5m2bK:
29.67
3mg0V-5m2bK:
28.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_2_BO221405_1
(PROTEASOME COMPONENT
PRE3
PROTEASOME COMPONENT
PUP1)		 5m2b PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 12 THR K   2
THR K   1
SER K 173
GLY K 172
ALA K 164
 None
7DX  K 301 (-3.3A)
None
None
MG  K 302 (-4.8A)
 0.93A 3mg02-5m2bK:
28.9
3mg0V-5m2bK:
29.7		 3mg02-5m2bK:
29.67
3mg0V-5m2bK:
28.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MG0_K_BO2K1402_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 5m2b PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		6 / 11 THR K   1
ALA K  20
ALA K  28
GLY K  47
ALA K  49
SER K 130
 7DX  K 301 (-3.3A)
7DX  K 301 ( 4.0A)
7DX  K 301 ( 4.6A)
7DX  K 301 (-3.8A)
7DX  K 301 (-3.2A)
7DX  K 301 (-3.1A)
 1.06A 3mg0K-5m2bK:
37.6
3mg0L-5m2bK:
24.0		 3mg0K-5m2bK:
76.89
3mg0L-5m2bK:
23.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MG0_K_BO2K1402_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 5m2b PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		7 / 11 THR K   1
ALA K  20
VAL K  31
LYS K  33
GLY K  47
ALA K  49
SER K 130
 7DX  K 301 (-3.3A)
7DX  K 301 ( 4.0A)
7DX  K 301 (-4.2A)
7DX  K 301 (-4.2A)
7DX  K 301 (-3.8A)
7DX  K 301 (-3.2A)
7DX  K 301 (-3.1A)
 0.55A 3mg0K-5m2bK:
37.6
3mg0L-5m2bK:
24.0		 3mg0K-5m2bK:
76.89
3mg0L-5m2bK:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_N_BO2N1404_1
(PROTEASOME COMPONENT
PRE3)		 5m2b PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 11 ALA K  28
SER K  46
GLY K  47
ALA K  49
SER K 170
 7DX  K 301 ( 4.6A)
None
7DX  K 301 (-3.8A)
7DX  K 301 (-3.2A)
None
 1.08A 3mg0N-5m2bK:
28.9		 3mg0N-5m2bK:
29.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_N_BO2N1404_1
(PROTEASOME COMPONENT
PRE3)		 5m2b PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 11 THR K   1
ALA K  28
SER K  46
GLY K  47
ALA K  49
 7DX  K 301 (-3.3A)
7DX  K 301 ( 4.6A)
None
7DX  K 301 (-3.8A)
7DX  K 301 (-3.2A)
 0.87A 3mg0N-5m2bK:
28.9		 3mg0N-5m2bK:
29.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_N_BO2N1404_1
(PROTEASOME COMPONENT
PRE3)		 5m2b PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 11 THR K   1
LYS K  33
SER K  46
GLY K  47
ALA K  49
 7DX  K 301 (-3.3A)
7DX  K 301 (-4.2A)
None
7DX  K 301 (-3.8A)
7DX  K 301 (-3.2A)
 0.39A 3mg0N-5m2bK:
28.9		 3mg0N-5m2bK:
29.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_N_BO2N1404_1
(PROTEASOME COMPONENT
PRE3)		 5m2b PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 11 THR K   2
THR K   1
SER K 173
GLY K 172
ALA K 164
 None
7DX  K 301 (-3.3A)
None
None
MG  K 302 (-4.8A)
 0.91A 3mg0N-5m2bK:
28.9		 3mg0N-5m2bK:
29.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MG0_Y_BO2Y1403_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 5m2b PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		8 / 12 THR K   1
ALA K  20
ALA K  22
VAL K  31
LYS K  33
GLY K  47
ALA K  49
SER K 130
 7DX  K 301 (-3.3A)
7DX  K 301 ( 4.0A)
None
7DX  K 301 (-4.2A)
7DX  K 301 (-4.2A)
7DX  K 301 (-3.8A)
7DX  K 301 (-3.2A)
7DX  K 301 (-3.1A)
 0.58A 3mg0Y-5m2bK:
24.9
3mg0Z-5m2bK:
23.7		 3mg0Y-5m2bK:
76.89
3mg0Z-5m2bK:
23.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MG0_Y_BO2Y1403_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 5m2b PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		6 / 12 THR K   1
ALA K  20
ALA K  28
GLY K  47
ALA K  49
SER K 130
 7DX  K 301 (-3.3A)
7DX  K 301 ( 4.0A)
7DX  K 301 ( 4.6A)
7DX  K 301 (-3.8A)
7DX  K 301 (-3.2A)
7DX  K 301 (-3.1A)
 1.10A 3mg0Y-5m2bK:
24.9
3mg0Z-5m2bK:
23.7		 3mg0Y-5m2bK:
76.89
3mg0Z-5m2bK:
23.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVL_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5m2b PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 11 THR K   1
ALA K  20
LYS K  33
MET K  45
GLY K  47
 7DX  K 301 (-3.3A)
7DX  K 301 ( 4.0A)
7DX  K 301 (-4.2A)
7DX  K 301 ( 3.8A)
7DX  K 301 (-3.8A)
 0.96A 4qvlK-5m2bK:
38.2
4qvlL-5m2bK:
24.1		 4qvlK-5m2bK:
76.89
4qvlL-5m2bK:
23.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVL_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5m2b PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		6 / 11 THR K   1
ALA K  20
LYS K  33
MET K  45
GLY K  47
ALA K  49
 7DX  K 301 (-3.3A)
7DX  K 301 ( 4.0A)
7DX  K 301 (-4.2A)
7DX  K 301 ( 3.8A)
7DX  K 301 (-3.8A)
7DX  K 301 (-3.2A)
 0.50A 4qvlK-5m2bK:
38.2
4qvlL-5m2bK:
24.1		 4qvlK-5m2bK:
76.89
4qvlL-5m2bK:
23.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVL_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5m2b PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 11 THR K   1
ALA K  20
LYS K  33
MET K  45
GLY K  47
 7DX  K 301 (-3.3A)
7DX  K 301 ( 4.0A)
7DX  K 301 (-4.2A)
7DX  K 301 ( 3.8A)
7DX  K 301 (-3.8A)
 0.96A 4qvlY-5m2bK:
23.9
4qvlZ-5m2bK:
23.9		 4qvlY-5m2bK:
76.89
4qvlZ-5m2bK:
23.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVL_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5m2b PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		6 / 11 THR K   1
ALA K  20
LYS K  33
MET K  45
GLY K  47
ALA K  49
 7DX  K 301 (-3.3A)
7DX  K 301 ( 4.0A)
7DX  K 301 (-4.2A)
7DX  K 301 ( 3.8A)
7DX  K 301 (-3.8A)
7DX  K 301 (-3.2A)
 0.50A 4qvlY-5m2bK:
23.9
4qvlZ-5m2bK:
23.9		 4qvlY-5m2bK:
76.89
4qvlZ-5m2bK:
23.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVM_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5m2b PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 9 THR K   1
ALA K  20
LYS K  33
GLY K  47
ALA K  49
 7DX  K 301 (-3.3A)
7DX  K 301 ( 4.0A)
7DX  K 301 (-4.2A)
7DX  K 301 (-3.8A)
7DX  K 301 (-3.2A)
 0.44A 4qvmK-5m2bK:
38.0
4qvmL-5m2bK:
24.1		 4qvmK-5m2bK:
76.42
4qvmL-5m2bK:
23.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVM_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5m2b PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 10 THR K   1
ALA K  20
LYS K  33
GLY K  47
ALA K  49
 7DX  K 301 (-3.3A)
7DX  K 301 ( 4.0A)
7DX  K 301 (-4.2A)
7DX  K 301 (-3.8A)
7DX  K 301 (-3.2A)
 0.43A 4qvmY-5m2bK:
30.8
4qvmZ-5m2bK:
23.8		 4qvmY-5m2bK:
76.42
4qvmZ-5m2bK:
23.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVN_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5m2b PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 9 THR K   1
ALA K  20
ALA K  28
GLY K  47
ALA K  49
 7DX  K 301 (-3.3A)
7DX  K 301 ( 4.0A)
7DX  K 301 ( 4.6A)
7DX  K 301 (-3.8A)
7DX  K 301 (-3.2A)
 1.18A 4qvnK-5m2bK:
38.0
4qvnL-5m2bK:
24.1		 4qvnK-5m2bK:
76.42
4qvnL-5m2bK:
23.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVN_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5m2b PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 9 THR K   1
ALA K  20
LYS K  33
GLY K  47
ALA K  49
 7DX  K 301 (-3.3A)
7DX  K 301 ( 4.0A)
7DX  K 301 (-4.2A)
7DX  K 301 (-3.8A)
7DX  K 301 (-3.2A)
 0.48A 4qvnK-5m2bK:
38.0
4qvnL-5m2bK:
24.1		 4qvnK-5m2bK:
76.42
4qvnL-5m2bK:
23.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVN_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5m2b PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 9 THR K   1
ALA K  20
ALA K  28
GLY K  47
ALA K  49
 7DX  K 301 (-3.3A)
7DX  K 301 ( 4.0A)
7DX  K 301 ( 4.6A)
7DX  K 301 (-3.8A)
7DX  K 301 (-3.2A)
 1.18A 4qvnY-5m2bK:
25.2
4qvnZ-5m2bK:
23.8		 4qvnY-5m2bK:
76.42
4qvnZ-5m2bK:
23.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVN_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5m2b PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 9 THR K   1
ALA K  20
LYS K  33
GLY K  47
ALA K  49
 7DX  K 301 (-3.3A)
7DX  K 301 ( 4.0A)
7DX  K 301 (-4.2A)
7DX  K 301 (-3.8A)
7DX  K 301 (-3.2A)
 0.50A 4qvnY-5m2bK:
25.2
4qvnZ-5m2bK:
23.8		 4qvnY-5m2bK:
76.42
4qvnZ-5m2bK:
23.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVP_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5m2b PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 10 THR K   1
ALA K  20
LYS K  33
GLY K  47
ALA K  49
 7DX  K 301 (-3.3A)
7DX  K 301 ( 4.0A)
7DX  K 301 (-4.2A)
7DX  K 301 (-3.8A)
7DX  K 301 (-3.2A)
 0.48A 4qvpK-5m2bK:
31.8
4qvpL-5m2bK:
23.8		 4qvpK-5m2bK:
76.42
4qvpL-5m2bK:
23.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVP_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5m2b PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 10 THR K   1
ALA K  20
LYS K  33
GLY K  47
ALA K  49
 7DX  K 301 (-3.3A)
7DX  K 301 ( 4.0A)
7DX  K 301 (-4.2A)
7DX  K 301 (-3.8A)
7DX  K 301 (-3.2A)
 0.47A 4qvpY-5m2bK:
24.0
4qvpZ-5m2bK:
23.9		 4qvpY-5m2bK:
76.42
4qvpZ-5m2bK:
23.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVQ_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5m2b PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 9 THR K   1
ALA K  20
ALA K  28
GLY K  47
ALA K  49
 7DX  K 301 (-3.3A)
7DX  K 301 ( 4.0A)
7DX  K 301 ( 4.6A)
7DX  K 301 (-3.8A)
7DX  K 301 (-3.2A)
 1.17A 4qvqK-5m2bK:
37.8
4qvqL-5m2bK:
24.1		 4qvqK-5m2bK:
76.42
4qvqL-5m2bK:
23.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVQ_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5m2b PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 9 THR K   1
ALA K  20
LYS K  33
GLY K  47
ALA K  49
 7DX  K 301 (-3.3A)
7DX  K 301 ( 4.0A)
7DX  K 301 (-4.2A)
7DX  K 301 (-3.8A)
7DX  K 301 (-3.2A)
 0.50A 4qvqK-5m2bK:
37.8
4qvqL-5m2bK:
24.1		 4qvqK-5m2bK:
76.42
4qvqL-5m2bK:
23.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVQ_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5m2b PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 9 THR K   1
ALA K  20
ALA K  28
GLY K  47
ALA K  49
 7DX  K 301 (-3.3A)
7DX  K 301 ( 4.0A)
7DX  K 301 ( 4.6A)
7DX  K 301 (-3.8A)
7DX  K 301 (-3.2A)
 1.16A 4qvqY-5m2bK:
30.7
4qvqZ-5m2bK:
23.8		 4qvqY-5m2bK:
76.42
4qvqZ-5m2bK:
23.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVQ_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5m2b PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 9 THR K   1
ALA K  20
LYS K  33
GLY K  47
ALA K  49
 7DX  K 301 (-3.3A)
7DX  K 301 ( 4.0A)
7DX  K 301 (-4.2A)
7DX  K 301 (-3.8A)
7DX  K 301 (-3.2A)
 0.50A 4qvqY-5m2bK:
30.7
4qvqZ-5m2bK:
23.8		 4qvqY-5m2bK:
76.42
4qvqZ-5m2bK:
23.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVV_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5m2b PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		4 / 8 THR K   1
LYS K  33
MET K  45
GLY K  47
 7DX  K 301 (-3.3A)
7DX  K 301 (-4.2A)
7DX  K 301 ( 3.8A)
7DX  K 301 (-3.8A)
 0.36A 4qvvK-5m2bK:
38.1
4qvvL-5m2bK:
24.0		 4qvvK-5m2bK:
76.42
4qvvL-5m2bK:
23.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVV_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5m2b PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		4 / 8 THR K   1
LYS K  33
MET K  45
GLY K  47
 7DX  K 301 (-3.3A)
7DX  K 301 (-4.2A)
7DX  K 301 ( 3.8A)
7DX  K 301 (-3.8A)
 0.35A 4qvvY-5m2bK:
30.8
4qvvZ-5m2bK:
23.8		 4qvvY-5m2bK:
76.42
4qvvZ-5m2bK:
23.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVW_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5m2b PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 11 THR K   1
ALA K  20
LYS K  33
MET K  45
GLY K  47
 7DX  K 301 (-3.3A)
7DX  K 301 ( 4.0A)
7DX  K 301 (-4.2A)
7DX  K 301 ( 3.8A)
7DX  K 301 (-3.8A)
 0.42A 4qvwK-5m2bK:
38.3
4qvwL-5m2bK:
24.1		 4qvwK-5m2bK:
76.42
4qvwL-5m2bK:
23.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVW_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5m2b PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 11 THR K   1
ALA K  20
LYS K  33
MET K  45
GLY K  47
 7DX  K 301 (-3.3A)
7DX  K 301 ( 4.0A)
7DX  K 301 (-4.2A)
7DX  K 301 ( 3.8A)
7DX  K 301 (-3.8A)
 0.96A 4qvwK-5m2bK:
38.3
4qvwL-5m2bK:
24.1		 4qvwK-5m2bK:
76.42
4qvwL-5m2bK:
23.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVW_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5m2b PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 11 THR K   1
ALA K  20
LYS K  33
MET K  45
GLY K  47
 7DX  K 301 (-3.3A)
7DX  K 301 ( 4.0A)
7DX  K 301 (-4.2A)
7DX  K 301 ( 3.8A)
7DX  K 301 (-3.8A)
 0.42A 4qvwY-5m2bK:
31.0
4qvwZ-5m2bK:
23.9		 4qvwY-5m2bK:
76.42
4qvwZ-5m2bK:
23.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVW_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5m2b PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 11 THR K   1
ALA K  20
LYS K  33
MET K  45
GLY K  47
 7DX  K 301 (-3.3A)
7DX  K 301 ( 4.0A)
7DX  K 301 (-4.2A)
7DX  K 301 ( 3.8A)
7DX  K 301 (-3.8A)
 0.96A 4qvwY-5m2bK:
31.0
4qvwZ-5m2bK:
23.9		 4qvwY-5m2bK:
76.42
4qvwZ-5m2bK:
23.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVY_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5m2b PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 10 ALA K  20
ALA K  22
VAL K  31
LYS K  33
GLY K  47
 7DX  K 301 ( 4.0A)
None
7DX  K 301 (-4.2A)
7DX  K 301 (-4.2A)
7DX  K 301 (-3.8A)
 0.92A 4qvyK-5m2bK:
38.4
4qvyL-5m2bK:
24.1		 4qvyK-5m2bK:
76.42
4qvyL-5m2bK:
23.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVY_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5m2b PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 10 THR K   1
ALA K  20
ALA K  22
VAL K  31
LYS K  33
 7DX  K 301 (-3.3A)
7DX  K 301 ( 4.0A)
None
7DX  K 301 (-4.2A)
7DX  K 301 (-4.2A)
 0.24A 4qvyK-5m2bK:
38.4
4qvyL-5m2bK:
24.1		 4qvyK-5m2bK:
76.42
4qvyL-5m2bK:
23.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVY_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5m2b PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 10 ALA K  20
ALA K  22
VAL K  31
LYS K  33
GLY K  47
 7DX  K 301 ( 4.0A)
None
7DX  K 301 (-4.2A)
7DX  K 301 (-4.2A)
7DX  K 301 (-3.8A)
 0.91A 4qvyY-5m2bK:
31.1
4qvyZ-5m2bK:
23.9		 4qvyY-5m2bK:
76.42
4qvyZ-5m2bK:
23.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVY_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5m2b PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 10 THR K   1
ALA K  20
ALA K  22
VAL K  31
LYS K  33
 7DX  K 301 (-3.3A)
7DX  K 301 ( 4.0A)
None
7DX  K 301 (-4.2A)
7DX  K 301 (-4.2A)
 0.24A 4qvyY-5m2bK:
31.1
4qvyZ-5m2bK:
23.9		 4qvyY-5m2bK:
76.42
4qvyZ-5m2bK:
23.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QW0_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5)		 5m2b PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 7 THR K   1
ALA K  20
ALA K  22
LYS K  33
MET K  45
 7DX  K 301 (-3.3A)
7DX  K 301 ( 4.0A)
None
7DX  K 301 (-4.2A)
7DX  K 301 ( 3.8A)
 0.21A 4qw0K-5m2bK:
38.2		 4qw0K-5m2bK:
75.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QW0_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5)		 5m2b PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 7 THR K   1
ALA K  20
ALA K  22
LYS K  33
MET K  45
 7DX  K 301 (-3.3A)
7DX  K 301 ( 4.0A)
None
7DX  K 301 (-4.2A)
7DX  K 301 ( 3.8A)
 0.18A 4qw0Y-5m2bK:
31.0		 4qw0Y-5m2bK:
75.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QW1_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5m2b PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 11 THR K   1
ALA K  20
LYS K  33
MET K  45
GLY K  47
 7DX  K 301 (-3.3A)
7DX  K 301 ( 4.0A)
7DX  K 301 (-4.2A)
7DX  K 301 ( 3.8A)
7DX  K 301 (-3.8A)
 0.92A 4qw1K-5m2bK:
38.2
4qw1L-5m2bK:
24.1		 4qw1K-5m2bK:
76.42
4qw1L-5m2bK:
23.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QW1_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5m2b PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		6 / 11 THR K   1
ALA K  20
LYS K  33
MET K  45
GLY K  47
ALA K  49
 7DX  K 301 (-3.3A)
7DX  K 301 ( 4.0A)
7DX  K 301 (-4.2A)
7DX  K 301 ( 3.8A)
7DX  K 301 (-3.8A)
7DX  K 301 (-3.2A)
 0.52A 4qw1K-5m2bK:
38.2
4qw1L-5m2bK:
24.1		 4qw1K-5m2bK:
76.42
4qw1L-5m2bK:
23.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QW1_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5m2b PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 10 THR K   1
ALA K  20
LYS K  33
MET K  45
GLY K  47
 7DX  K 301 (-3.3A)
7DX  K 301 ( 4.0A)
7DX  K 301 (-4.2A)
7DX  K 301 ( 3.8A)
7DX  K 301 (-3.8A)
 0.92A 4qw1Y-5m2bK:
25.4
4qw1Z-5m2bK:
23.9		 4qw1Y-5m2bK:
76.42
4qw1Z-5m2bK:
23.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QW1_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5m2b PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		6 / 10 THR K   1
ALA K  20
LYS K  33
MET K  45
GLY K  47
ALA K  49
 7DX  K 301 (-3.3A)
7DX  K 301 ( 4.0A)
7DX  K 301 (-4.2A)
7DX  K 301 ( 3.8A)
7DX  K 301 (-3.8A)
7DX  K 301 (-3.2A)
 0.52A 4qw1Y-5m2bK:
25.4
4qw1Z-5m2bK:
23.9		 4qw1Y-5m2bK:
76.42
4qw1Z-5m2bK:
23.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QW3_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5m2b PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		6 / 10 THR K   1
ALA K  20
LYS K  33
MET K  45
GLY K  47
ALA K  49
 7DX  K 301 (-3.3A)
7DX  K 301 ( 4.0A)
7DX  K 301 (-4.2A)
7DX  K 301 ( 3.8A)
7DX  K 301 (-3.8A)
7DX  K 301 (-3.2A)
 0.47A 4qw3K-5m2bK:
37.8
4qw3L-5m2bK:
24.0		 4qw3K-5m2bK:
76.42
4qw3L-5m2bK:
23.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QW3_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5m2b PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		6 / 10 THR K   1
ALA K  20
LYS K  33
MET K  45
GLY K  47
ALA K  49
 7DX  K 301 (-3.3A)
7DX  K 301 ( 4.0A)
7DX  K 301 (-4.2A)
7DX  K 301 ( 3.8A)
7DX  K 301 (-3.8A)
7DX  K 301 (-3.2A)
 0.47A 4qw3Y-5m2bK:
30.6
4qw3Z-5m2bK:
23.7		 4qw3Y-5m2bK:
76.42
4qw3Z-5m2bK:
23.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QWU_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5m2b PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 9 THR K   1
ALA K  20
ALA K  28
MET K  45
GLY K  47
 7DX  K 301 (-3.3A)
7DX  K 301 ( 4.0A)
7DX  K 301 ( 4.6A)
7DX  K 301 ( 3.8A)
7DX  K 301 (-3.8A)
 1.18A 4qwuK-5m2bK:
37.1
4qwuL-5m2bK:
23.9		 4qwuK-5m2bK:
76.42
4qwuL-5m2bK:
23.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QWU_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5m2b PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 9 THR K   1
ALA K  20
LYS K  33
MET K  45
GLY K  47
 7DX  K 301 (-3.3A)
7DX  K 301 ( 4.0A)
7DX  K 301 (-4.2A)
7DX  K 301 ( 3.8A)
7DX  K 301 (-3.8A)
 0.54A 4qwuK-5m2bK:
37.1
4qwuL-5m2bK:
23.9		 4qwuK-5m2bK:
76.42
4qwuL-5m2bK:
23.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QWU_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5m2b PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 9 THR K   1
ALA K  20
LYS K  33
MET K  45
GLY K  47
 7DX  K 301 (-3.3A)
7DX  K 301 ( 4.0A)
7DX  K 301 (-4.2A)
7DX  K 301 ( 3.8A)
7DX  K 301 (-3.8A)
 0.54A 4qwuY-5m2bK:
25.2
4qwuZ-5m2bK:
23.9		 4qwuY-5m2bK:
76.42
4qwuZ-5m2bK:
23.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5BXN_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5m2b PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		6 / 11 THR K   1
ALA K  20
LYS K  33
MET K  45
GLY K  47
ALA K  49
 7DX  K 301 (-3.3A)
7DX  K 301 ( 4.0A)
7DX  K 301 (-4.2A)
7DX  K 301 ( 3.8A)
7DX  K 301 (-3.8A)
7DX  K 301 (-3.2A)
 0.50A 5bxnK-5m2bK:
38.1
5bxnL-5m2bK:
23.8		 5bxnK-5m2bK:
76.89
5bxnL-5m2bK:
23.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5BXN_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5m2b PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		6 / 11 THR K   1
ALA K  20
LYS K  33
MET K  45
GLY K  47
ALA K  49
 7DX  K 301 (-3.3A)
7DX  K 301 ( 4.0A)
7DX  K 301 (-4.2A)
7DX  K 301 ( 3.8A)
7DX  K 301 (-3.8A)
7DX  K 301 (-3.2A)
 0.50A 5bxnY-5m2bK:
25.3
5bxnZ-5m2bK:
23.8		 5bxnY-5m2bK:
76.89
5bxnZ-5m2bK:
23.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L5F_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 5m2b PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		7 / 9 THR K   1
SER K  21
SER K  27
VAL K  31
LYS K  33
MET K  45
ALA K  49
 7DX  K 301 (-3.3A)
None
7DX  K 301 ( 4.2A)
7DX  K 301 (-4.2A)
7DX  K 301 (-4.2A)
7DX  K 301 ( 3.8A)
7DX  K 301 (-3.2A)
 0.36A 5l5fK-5m2bK:
40.1
5l5fL-5m2bK:
23.8		 5l5fK-5m2bK:
100.00
5l5fL-5m2bK:
23.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L5F_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 5m2b PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		6 / 8 THR K   1
SER K  21
SER K  27
LYS K  33
MET K  45
ALA K  49
 7DX  K 301 (-3.3A)
None
7DX  K 301 ( 4.2A)
7DX  K 301 (-4.2A)
7DX  K 301 ( 3.8A)
7DX  K 301 (-3.2A)
 0.20A 5l5fY-5m2bK:
40.0
5l5fZ-5m2bK:
23.9		 5l5fY-5m2bK:
100.00
5l5fZ-5m2bK:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5m2b PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 12 THR K   1
LYS K  33
SER K  46
GLY K  47
ALA K  49
 7DX  K 301 (-3.3A)
7DX  K 301 (-4.2A)
None
7DX  K 301 (-3.8A)
7DX  K 301 (-3.2A)
 0.33A 5l5zV-5m2bK:
29.7
5l5zb-5m2bK:
29.0		 5l5zV-5m2bK:
28.33
5l5zb-5m2bK:
29.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5m2b PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 12 THR K   2
THR K   1
SER K 173
GLY K 172
ALA K 164
 None
7DX  K 301 (-3.3A)
None
None
MG  K 302 (-4.8A)
 0.94A 5l5zV-5m2bK:
29.7
5l5zb-5m2bK:
29.0		 5l5zV-5m2bK:
28.33
5l5zb-5m2bK:
29.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L5Z_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 5m2b PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		6 / 9 THR K   1
ALA K  20
ALA K  22
LYS K  33
GLY K  47
ALA K  49
 7DX  K 301 (-3.3A)
7DX  K 301 ( 4.0A)
None
7DX  K 301 (-4.2A)
7DX  K 301 (-3.8A)
7DX  K 301 (-3.2A)
 0.41A 5l5zK-5m2bK:
39.2
5l5zL-5m2bK:
23.9		 5l5zK-5m2bK:
83.41
5l5zL-5m2bK:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5m2b PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 12 THR K   1
LYS K  33
SER K  46
GLY K  47
ALA K  49
 7DX  K 301 (-3.3A)
7DX  K 301 (-4.2A)
None
7DX  K 301 (-3.8A)
7DX  K 301 (-3.2A)
 0.33A 5l5zH-5m2bK:
28.0
5l5zN-5m2bK:
29.0		 5l5zH-5m2bK:
28.33
5l5zN-5m2bK:
29.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5m2b PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 12 THR K   2
THR K   1
SER K 173
GLY K 172
ALA K 164
 None
7DX  K 301 (-3.3A)
None
None
MG  K 302 (-4.8A)
 0.94A 5l5zH-5m2bK:
28.0
5l5zN-5m2bK:
29.0		 5l5zH-5m2bK:
28.33
5l5zN-5m2bK:
29.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L5Z_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 5m2b PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		6 / 9 THR K   1
ALA K  20
ALA K  22
LYS K  33
GLY K  47
ALA K  49
 7DX  K 301 (-3.3A)
7DX  K 301 ( 4.0A)
None
7DX  K 301 (-4.2A)
7DX  K 301 (-3.8A)
7DX  K 301 (-3.2A)
 0.41A 5l5zY-5m2bK:
39.2
5l5zZ-5m2bK:
23.9		 5l5zY-5m2bK:
83.41
5l5zZ-5m2bK:
23.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L66_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 5m2b PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		7 / 10 THR K   1
ALA K  20
SER K  27
LYS K  33
MET K  45
GLY K  47
ALA K  49
 7DX  K 301 (-3.3A)
7DX  K 301 ( 4.0A)
7DX  K 301 ( 4.2A)
7DX  K 301 (-4.2A)
7DX  K 301 ( 3.8A)
7DX  K 301 (-3.8A)
7DX  K 301 (-3.2A)
 0.36A 5l66K-5m2bK:
39.7
5l66L-5m2bK:
24.1		 5l66K-5m2bK:
96.21
5l66L-5m2bK:
23.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L66_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 5m2b PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		7 / 10 THR K   1
ALA K  20
SER K  27
LYS K  33
MET K  45
GLY K  47
ALA K  49
 7DX  K 301 (-3.3A)
7DX  K 301 ( 4.0A)
7DX  K 301 ( 4.2A)
7DX  K 301 (-4.2A)
7DX  K 301 ( 3.8A)
7DX  K 301 (-3.8A)
7DX  K 301 (-3.2A)
 0.35A 5l66Y-5m2bK:
39.6
5l66Z-5m2bK:
23.9		 5l66Y-5m2bK:
96.21
5l66Z-5m2bK:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_B_BO2B305_1
(PROTEASOME SUBUNIT
BETA TYPE-6)		 5m2b PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 12 THR K   1
LYS K  33
SER K  46
GLY K  47
ALA K  49
 7DX  K 301 (-3.3A)
7DX  K 301 (-4.2A)
None
7DX  K 301 (-3.8A)
7DX  K 301 (-3.2A)
 0.43A 5lf3b-5m2bK:
28.8		 5lf3b-5m2bK:
29.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_B_BO2B305_1
(PROTEASOME SUBUNIT
BETA TYPE-6)		 5m2b PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 12 THR K   2
THR K   1
SER K 173
GLY K 172
ALA K 164
 None
7DX  K 301 (-3.3A)
None
None
MG  K 302 (-4.8A)
 0.95A 5lf3b-5m2bK:
28.8		 5lf3b-5m2bK:
29.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LF3_K_BO2K305_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-1)		 5m2b PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		8 / 11 THR K   1
ALA K  20
ALA K  22
LYS K  33
MET K  45
GLY K  47
ALA K  49
TYR K 169
 7DX  K 301 (-3.3A)
7DX  K 301 ( 4.0A)
None
7DX  K 301 (-4.2A)
7DX  K 301 ( 3.8A)
7DX  K 301 (-3.8A)
7DX  K 301 (-3.2A)
None
 0.59A 5lf3K-5m2bK:
35.8
5lf3L-5m2bK:
25.1		 5lf3K-5m2bK:
66.18
5lf3L-5m2bK:
25.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LF3_K_BO2K305_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-1)		 5m2b PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		6 / 11 THR K   1
ALA K  20
LYS K  33
MET K  45
GLY K  47
TYR K 169
 7DX  K 301 (-3.3A)
7DX  K 301 ( 4.0A)
7DX  K 301 (-4.2A)
7DX  K 301 ( 3.8A)
7DX  K 301 (-3.8A)
None
 0.93A 5lf3K-5m2bK:
35.8
5lf3L-5m2bK:
25.1		 5lf3K-5m2bK:
66.18
5lf3L-5m2bK:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_N_BO2N304_1
(PROTEASOME SUBUNIT
BETA TYPE-6)		 5m2b PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 12 THR K   1
LYS K  33
SER K  46
GLY K  47
ALA K  49
 7DX  K 301 (-3.3A)
7DX  K 301 (-4.2A)
None
7DX  K 301 (-3.8A)
7DX  K 301 (-3.2A)
 0.43A 5lf3N-5m2bK:
28.9		 5lf3N-5m2bK:
29.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_N_BO2N304_1
(PROTEASOME SUBUNIT
BETA TYPE-6)		 5m2b PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 12 THR K   2
THR K   1
SER K 173
GLY K 172
ALA K 164
 None
7DX  K 301 (-3.3A)
None
None
MG  K 302 (-4.8A)
 0.96A 5lf3N-5m2bK:
28.9		 5lf3N-5m2bK:
29.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_V_BO2V303_1
(PROTEASOME SUBUNIT
BETA TYPE-7
PROTEASOME SUBUNIT
BETA TYPE-3)		 5m2b PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		5 / 10 THR K   1
ALA K  20
LYS K  33
GLY K  47
ALA K  49
 7DX  K 301 (-3.3A)
7DX  K 301 ( 4.0A)
7DX  K 301 (-4.2A)
7DX  K 301 (-3.8A)
7DX  K 301 (-3.2A)
 0.46A 5lf3V-5m2bK:
30.5
5lf3W-5m2bK:
25.9		 5lf3V-5m2bK:
26.07
5lf3W-5m2bK:
24.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LF3_Y_BO2Y305_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-1)		 5m2b PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		8 / 11 THR K   1
ALA K  20
ALA K  22
LYS K  33
MET K  45
GLY K  47
ALA K  49
TYR K 169
 7DX  K 301 (-3.3A)
7DX  K 301 ( 4.0A)
None
7DX  K 301 (-4.2A)
7DX  K 301 ( 3.8A)
7DX  K 301 (-3.8A)
7DX  K 301 (-3.2A)
None
 0.57A 5lf3Y-5m2bK:
35.8
5lf3Z-5m2bK:
25.1		 5lf3Y-5m2bK:
66.18
5lf3Z-5m2bK:
25.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LF3_Y_BO2Y305_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-1)		 5m2b PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
(Homo
sapiens;
Saccharomyces
cerevisiae) 		6 / 11 THR K   1
ALA K  20
LYS K  33
MET K  45
GLY K  47
TYR K 169
 7DX  K 301 (-3.3A)
7DX  K 301 ( 4.0A)
7DX  K 301 (-4.2A)
7DX  K 301 ( 3.8A)
7DX  K 301 (-3.8A)
None
 0.92A 5lf3Y-5m2bK:
35.8
5lf3Z-5m2bK:
25.1		 5lf3Y-5m2bK:
66.18
5lf3Z-5m2bK:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_B_6V8B304_0
(PROTEASOME SUBUNIT
BETA TYPE-6
PROTEASOME SUBUNIT
BETA TYPE-7)		 5m2b PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
(Saccharomyces
cerevisiae;
Homo
sapiens) 		5 / 12 THR K   1
ALA K  28
SER K  46
GLY K  47
ALA K  49
 7DX  K 301 (-3.3A)
7DX  K 301 ( 4.6A)
None
7DX  K 301 (-3.8A)
7DX  K 301 (-3.2A)
 0.86A 5lf7V-5m2bK:
30.5
5lf7b-5m2bK:
28.9		 5lf7V-5m2bK:
26.07
5lf7b-5m2bK:
29.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_B_6V8B304_0
(PROTEASOME SUBUNIT
BETA TYPE-6
PROTEASOME SUBUNIT
BETA TYPE-7)		 5m2b PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
(Saccharomyces
cerevisiae;
Homo
sapiens) 		5 / 12 THR K   1
LYS K  33
SER K  46
GLY K  47
ALA K  49
 7DX  K 301 (-3.3A)
7DX  K 301 (-4.2A)
None
7DX  K 301 (-3.8A)
7DX  K 301 (-3.2A)
 0.43A 5lf7V-5m2bK:
30.5
5lf7b-5m2bK:
28.9		 5lf7V-5m2bK:
26.07
5lf7b-5m2bK:
29.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_B_6V8B304_0
(PROTEASOME SUBUNIT
BETA TYPE-6
PROTEASOME SUBUNIT
BETA TYPE-7)		 5m2b PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
(Saccharomyces
cerevisiae;
Homo
sapiens) 		6 / 12 TYR K 134
THR K   2
THR K   1
SER K 173
GLY K 172
ALA K 164
 None
None
7DX  K 301 (-3.3A)
None
None
MG  K 302 (-4.8A)
 1.32A 5lf7V-5m2bK:
30.5
5lf7b-5m2bK:
28.9		 5lf7V-5m2bK:
26.07
5lf7b-5m2bK:
29.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LF7_K_6V8K305_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-5)		 5m2b PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
(Saccharomyces
cerevisiae;
Homo
sapiens) 		7 / 11 THR K   1
ALA K  20
ALA K  22
VAL K  31
LYS K  33
MET K  45
GLY K  47
 7DX  K 301 (-3.3A)
7DX  K 301 ( 4.0A)
None
7DX  K 301 (-4.2A)
7DX  K 301 (-4.2A)
7DX  K 301 ( 3.8A)
7DX  K 301 (-3.8A)
 0.48A 5lf7K-5m2bK:
35.6
5lf7L-5m2bK:
25.1		 5lf7K-5m2bK:
66.18
5lf7L-5m2bK:
25.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LF7_K_6V8K305_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-5)		 5m2b PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
(Saccharomyces
cerevisiae;
Homo
sapiens) 		6 / 11 THR K   1
ALA K  20
VAL K  31
LYS K  33
MET K  45
GLY K  47
 7DX  K 301 (-3.3A)
7DX  K 301 ( 4.0A)
7DX  K 301 (-4.2A)
7DX  K 301 (-4.2A)
7DX  K 301 ( 3.8A)
7DX  K 301 (-3.8A)
 0.94A 5lf7K-5m2bK:
35.6
5lf7L-5m2bK:
25.1		 5lf7K-5m2bK:
66.18
5lf7L-5m2bK:
25.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LF7_K_6V8K305_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-5)		 5m2b PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
(Saccharomyces
cerevisiae;
Homo
sapiens) 		7 / 11 THR K   1
ALA K  20
VAL K  31
LYS K  33
MET K  45
GLY K  47
ALA K  49
 7DX  K 301 (-3.3A)
7DX  K 301 ( 4.0A)
7DX  K 301 (-4.2A)
7DX  K 301 (-4.2A)
7DX  K 301 ( 3.8A)
7DX  K 301 (-3.8A)
7DX  K 301 (-3.2A)
 0.60A 5lf7K-5m2bK:
35.6
5lf7L-5m2bK:
25.1		 5lf7K-5m2bK:
66.18
5lf7L-5m2bK:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_N_6V8N305_0
(PROTEASOME SUBUNIT
BETA TYPE-6
PROTEASOME SUBUNIT
BETA TYPE-7)		 5m2b PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
(Saccharomyces
cerevisiae;
Homo
sapiens) 		5 / 12 THR K   1
ALA K  28
SER K  46
GLY K  47
ALA K  49
 7DX  K 301 (-3.3A)
7DX  K 301 ( 4.6A)
None
7DX  K 301 (-3.8A)
7DX  K 301 (-3.2A)
 0.86A 5lf7H-5m2bK:
30.5
5lf7N-5m2bK:
28.9		 5lf7H-5m2bK:
26.07
5lf7N-5m2bK:
29.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_N_6V8N305_0
(PROTEASOME SUBUNIT
BETA TYPE-6
PROTEASOME SUBUNIT
BETA TYPE-7)		 5m2b PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
(Saccharomyces
cerevisiae;
Homo
sapiens) 		5 / 12 THR K   1
LYS K  33
SER K  46
GLY K  47
ALA K  49
 7DX  K 301 (-3.3A)
7DX  K 301 (-4.2A)
None
7DX  K 301 (-3.8A)
7DX  K 301 (-3.2A)
 0.44A 5lf7H-5m2bK:
30.5
5lf7N-5m2bK:
28.9		 5lf7H-5m2bK:
26.07
5lf7N-5m2bK:
29.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_N_6V8N305_0
(PROTEASOME SUBUNIT
BETA TYPE-6
PROTEASOME SUBUNIT
BETA TYPE-7)		 5m2b PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
(Saccharomyces
cerevisiae;
Homo
sapiens) 		6 / 12 TYR K 134
THR K   2
THR K   1
SER K 173
GLY K 172
ALA K 164
 None
None
7DX  K 301 (-3.3A)
None
None
MG  K 302 (-4.8A)
 1.34A 5lf7H-5m2bK:
30.5
5lf7N-5m2bK:
28.9		 5lf7H-5m2bK:
26.07
5lf7N-5m2bK:
29.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LF7_Y_6V8Y306_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-5)		 5m2b PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
(Saccharomyces
cerevisiae;
Homo
sapiens) 		7 / 11 THR K   1
ALA K  20
ALA K  22
VAL K  31
LYS K  33
MET K  45
GLY K  47
 7DX  K 301 (-3.3A)
7DX  K 301 ( 4.0A)
None
7DX  K 301 (-4.2A)
7DX  K 301 (-4.2A)
7DX  K 301 ( 3.8A)
7DX  K 301 (-3.8A)
 0.46A 5lf7Y-5m2bK:
35.7
5lf7Z-5m2bK:
25.1		 5lf7Y-5m2bK:
66.18
5lf7Z-5m2bK:
25.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LF7_Y_6V8Y306_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-5)		 5m2b PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
(Saccharomyces
cerevisiae;
Homo
sapiens) 		6 / 11 THR K   1
ALA K  20
VAL K  31
LYS K  33
MET K  45
GLY K  47
 7DX  K 301 (-3.3A)
7DX  K 301 ( 4.0A)
7DX  K 301 (-4.2A)
7DX  K 301 (-4.2A)
7DX  K 301 ( 3.8A)
7DX  K 301 (-3.8A)
 0.92A 5lf7Y-5m2bK:
35.7
5lf7Z-5m2bK:
25.1		 5lf7Y-5m2bK:
66.18
5lf7Z-5m2bK:
25.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LF7_Y_6V8Y306_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-5)		 5m2b PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
(Saccharomyces
cerevisiae;
Homo
sapiens) 		7 / 11 THR K   1
ALA K  20
VAL K  31
LYS K  33
MET K  45
GLY K  47
ALA K  49
 7DX  K 301 (-3.3A)
7DX  K 301 ( 4.0A)
7DX  K 301 (-4.2A)
7DX  K 301 (-4.2A)
7DX  K 301 ( 3.8A)
7DX  K 301 (-3.8A)
7DX  K 301 (-3.2A)
 0.60A 5lf7Y-5m2bK:
35.7
5lf7Z-5m2bK:
25.1		 5lf7Y-5m2bK:
66.18
5lf7Z-5m2bK:
25.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6HWD_K_BO2K301_0
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5m2b PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
(Saccharomyces
cerevisiae;
Homo
sapiens) 		7 / 11 THR K   1
ALA K  20
ALA K  22
LYS K  33
MET K  45
GLY K  47
ALA K  49
 7DX  K 301 (-3.3A)
7DX  K 301 ( 4.0A)
None
7DX  K 301 (-4.2A)
7DX  K 301 ( 3.8A)
7DX  K 301 (-3.8A)
7DX  K 301 (-3.2A)
 0.60A 6hwdK-5m2bK:
37.3
6hwdL-5m2bK:
24.1		 6hwdK-5m2bK:
66.25
6hwdL-5m2bK:
17.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6HWD_Y_BO2Y301_0
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5m2b PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
(Saccharomyces
cerevisiae;
Homo
sapiens) 		7 / 11 THR K   1
ALA K  20
ALA K  22
LYS K  33
MET K  45
GLY K  47
ALA K  49
 7DX  K 301 (-3.3A)
7DX  K 301 ( 4.0A)
None
7DX  K 301 (-4.2A)
7DX  K 301 ( 3.8A)
7DX  K 301 (-3.8A)
7DX  K 301 (-3.2A)
 0.59A 6hwdY-5m2bK:
24.8
6hwdZ-5m2bK:
23.9		 6hwdY-5m2bK:
66.25
6hwdZ-5m2bK:
17.22