SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '7DC'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NC3_A_ERMA1202_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 5m23 WD REPEAT-CONTAINING
PROTEIN 5
(Homo
sapiens) 		5 / 12 ASP A  92
SER A  50
VAL A 145
ALA A 308
PHE A 219
 7DC  A 401 ( 4.3A)
None
None
None
None
 1.31A 4nc3A-5m23A:
undetectable		 4nc3A-5m23A:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O8Z_A_BBIA402_1
(NAD-DEPENDENT
PROTEIN DEACETYLASE
SIRTUIN-3,
MITOCHONDRIAL)		 5m23 WD REPEAT-CONTAINING
PROTEIN 5
(Homo
sapiens) 		4 / 5 PHE A 263
PHE A 219
LEU A 234
PRO A 216
 7DC  A 401 (-3.9A)
None
None
None
 1.44A 4o8zA-5m23A:
undetectable		 4o8zA-5m23A:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DRY_A_H8DA2001_0
(5HT2B RECEPTOR, BRIL
CHIMERA)		 5m23 WD REPEAT-CONTAINING
PROTEIN 5
(Homo
sapiens) 		5 / 11 ASP A  92
SER A  50
VAL A 145
ALA A 308
PHE A 219
 7DC  A 401 ( 4.3A)
None
None
None
None
 1.32A 6dryA-5m23A:
undetectable		 6dryA-5m23A:
19.92