SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '79M'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MZ9_A_VDYA1002_4 (CARTILAGE OLIGOMERIC MATRIX PROTEIN)	5oc9	- (-)	4 / 5	LEU A 429 VAL A 514 CYH A 513 ALA A 247	None None None 79M A 707 ( 3.7A)	1.15A	1mz9D-5oc9A: undetectable	1mz9D-5oc9A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MZ9_A_VDYA1002_5 (CARTILAGE OLIGOMERIC MATRIX PROTEIN)	5oc9	- (-)	4 / 4	LEU A 429 VAL A 514 CYH A 513 ALA A 247	None None None 79M A 707 ( 3.7A)	1.29A	1mz9E-5oc9A: undetectable	1mz9E-5oc9A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1YAJ_G_BEZG3385_0 (CES1 PROTEIN)	5oc9	- (-)	3 / 3	SER A 248 VAL A 598 LEU A 602	79M A 707 (-3.5A) 79M A 707 ( 4.9A) None	0.68A	1yajG-5oc9A: undetectable	1yajG-5oc9A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WNU_C_QDNC602_1 (CYTOCHROME P450 2D6)	5oc9	- (-)	5 / 11	LEU A 258 GLY A 506 LEU A 510 PHE A 502 ALA A 558	None None None None 79M A 711 ( 4.3A)	1.31A	4wnuC-5oc9A: undetectable	4wnuC-5oc9A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5LJB_A_RTLA201_0 (RETINOL-BINDING PROTEIN 1)	5oc9	- (-)	5 / 12	PHE A 559 LEU A 405 ALA A 558 TYR A 507 LEU A 222	None None 79M A 711 ( 4.3A) None None	1.37A	5ljbA-5oc9A: undetectable	5ljbA-5oc9A: undetectable

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1MZ9_A_VDYA1002_4","CARTILAGE OLIGOMERIC MATRIX PROTEIN;CARTILAGE OLIGOMERIC MATRIX PROTEIN","5oc9","-","-",4,"LEU A 429;VAL A 514;CYH A 513;ALA A 247","None;None;None;79M A 707 ( 3.7A)","1.15A","1mz9D-5oc9A:undetectable",null],["1MZ9_A_VDYA1002_5","CARTILAGE OLIGOMERIC MATRIX PROTEIN;CARTILAGE OLIGOMERIC MATRIX PROTEIN","5oc9","-","-",4,"LEU A 429;VAL A 514;CYH A 513;ALA A 247","None;None;None;79M A 707 ( 3.7A)","1.29A","1mz9E-5oc9A:undetectable","1mz9D-5oc9A:undetectable"],["1YAJ_G_BEZG3385_0","CES1 PROTEIN","5oc9","-","-",3,"SER A 248;VAL A 598;LEU A 602","79M A 707 (-3.5A);79M A 707 ( 4.9A);None","0.68A","1yajG-5oc9A:undetectable","1mz9E-5oc9A:undetectable"],["4WNU_C_QDNC602_1","CYTOCHROME P450 2D6","5oc9","-","-",5,"LEU A 258;GLY A 506;LEU A 510;PHE A 502;ALA A 558","None;None;None;None;79M A 711 ( 4.3A)","1.31A","4wnuC-5oc9A:undetectable","1yajG-5oc9A:undetectable"],["5LJB_A_RTLA201_0","RETINOL-BINDING PROTEIN 1","5oc9","-","-",5,"PHE A 559;LEU A 405;ALA A 558;TYR A 507;LEU A 222","None;None;79M A 711 ( 4.3A);None;None","1.37A","5ljbA-5oc9A:undetectable","4wnuC-5oc9A:undetectable"]]