SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '75C'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BDW_B_DVAB8_0
(GRAMICIDIN A)		 5ja1 ENTEROBACTIN
SYNTHASE COMPONENT F
(Escherichia
coli) 		3 / 3 VAL A 753
VAL A 755
TRP A 652
 75C  A1301 (-4.7A)
None
None
 0.98A 1bdwA-5ja1A:
undetectable
1bdwB-5ja1A:
undetectable		 1bdwA-5ja1A:
2.26
1bdwB-5ja1A:
2.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WD9_A_IBPA1570_1
(ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL)		 5ja1 ENTEROBACTIN
SYNTHASE COMPONENT F
(Escherichia
coli) 		4 / 7 GLY A 723
GLY A 747
THR A 749
ARG A 866
 75C  A1301 (-3.4A)
75C  A1301 (-4.7A)
75C  A1301 (-4.5A)
75C  A1301 (-4.0A)
 0.33A 2wd9A-5ja1A:
39.6		 2wd9A-5ja1A:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WD9_B_IBPB1570_1
(ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL)		 5ja1 ENTEROBACTIN
SYNTHASE COMPONENT F
(Escherichia
coli) 		4 / 8 GLY A 723
GLY A 747
THR A 749
ARG A 866
 75C  A1301 (-3.4A)
75C  A1301 (-4.7A)
75C  A1301 (-4.5A)
75C  A1301 (-4.0A)
 0.30A 2wd9B-5ja1A:
41.3		 2wd9B-5ja1A:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WD9_C_IBPC1570_1
(ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL)		 5ja1 ENTEROBACTIN
SYNTHASE COMPONENT F
(Escherichia
coli) 		5 / 10 THR A 603
GLY A 723
GLY A 747
THR A 749
ARG A 866
 None
75C  A1301 (-3.4A)
75C  A1301 (-4.7A)
75C  A1301 (-4.5A)
75C  A1301 (-4.0A)
 0.51A 2wd9C-5ja1A:
41.0		 2wd9C-5ja1A:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VNS_A_DVAA602_0
(NRPS ADENYLATION
PROTEIN CYTC1)		 5ja1 ENTEROBACTIN
SYNTHASE COMPONENT F
(Escherichia
coli) 		4 / 7 ASP A 648
GLY A 723
THR A 749
LYS A 861
 75C  A1301 (-3.3A)
75C  A1301 (-3.4A)
75C  A1301 (-4.5A)
75C  A1301 ( 2.8A)
 0.81A 3vnsA-5ja1A:
49.1		 3vnsA-5ja1A:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZXI_A_GLYA1402_0
(TYROCIDINE
SYNTHETASE 3)		 5ja1 ENTEROBACTIN
SYNTHASE COMPONENT F
(Escherichia
coli) 		4 / 7 ASP A 648
GLY A 723
THR A 749
LYS A 861
 75C  A1301 (-3.3A)
75C  A1301 (-3.4A)
75C  A1301 (-4.5A)
75C  A1301 ( 2.8A)
 1.14A 4zxiA-5ja1A:
48.9		 4zxiA-5ja1A:
28.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BW4_B_SAMB301_1
(16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE)		 5ja1 ENTEROBACTIN
SYNTHASE COMPONENT F
(Escherichia
coli) 		3 / 3 ASP A 840
GLU A 750
SER A 772
 75C  A1301 (-3.0A)
None
None
 0.81A 5bw4B-5ja1A:
undetectable		 5bw4B-5ja1A:
13.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KKL_B_SAMB8009_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN,HISTONE H3.1
PEPTIDE,ZINC FINGER
DOMAIN-CONTAINING
PROTEIN)		 5ja1 ENTEROBACTIN
SYNTHASE COMPONENT F
(Escherichia
coli) 		5 / 12 LEU A 745
GLY A 723
TYR A 852
ASN A 744
LEU A 742
 None
75C  A1301 (-3.4A)
75C  A1301 (-3.8A)
75C  A1301 (-3.3A)
None
 1.50A 5kklB-5ja1A:
2.5		 5kklB-5ja1A:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CBZ_A_ESTA601_1
(ESTROGEN RECEPTOR)		 5ja1 ENTEROBACTIN
BIOSYNTHESIS PROTEIN
YBDZ
ENTEROBACTIN
SYNTHASE COMPONENT F
(Escherichia
coli) 		4 / 8 LEU A 819
GLU A 750
ARG A 866
LEU B  60
 None
None
75C  A1301 (-4.0A)
None
 0.99A 6cbzA-5ja1A:
undetectable		 6cbzA-5ja1A:
4.92