SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '73B'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U5J_A_08HA1_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 4uyg BROMODOMAIN-CONTAINI
NG PROTEIN 2
(Homo
sapiens) 		6 / 7 TRP A 370
PRO A 371
LEU A 381
LEU A 383
ASN A 429
MET A 438
 None
None
73B  A1456 (-4.9A)
73B  A1456 (-4.9A)
73B  A1456 (-3.3A)
73B  A1456 ( 3.8A)
 0.53A 3u5jA-4uygA:
17.8		 3u5jA-4uygA:
34.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U5K_A_08JA1_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 4uyg BROMODOMAIN-CONTAINI
NG PROTEIN 2
(Homo
sapiens) 		7 / 8 TRP A 370
PRO A 371
VAL A 376
LEU A 381
LEU A 383
ASN A 429
MET A 438
 None
None
73B  A1456 (-4.0A)
73B  A1456 (-4.9A)
73B  A1456 (-4.9A)
73B  A1456 (-3.3A)
73B  A1456 ( 3.8A)
 0.52A 3u5kA-4uygA:
17.9		 3u5kA-4uygA:
34.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U5K_B_08JB2_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 4uyg BROMODOMAIN-CONTAINI
NG PROTEIN 2
(Homo
sapiens) 		6 / 7 TRP A 370
PRO A 371
VAL A 376
LEU A 381
LEU A 383
ASN A 429
 None
None
73B  A1456 (-4.0A)
73B  A1456 (-4.9A)
73B  A1456 (-4.9A)
73B  A1456 (-3.3A)
 0.43A 3u5kB-4uygA:
18.0		 3u5kB-4uygA:
34.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U5K_C_08JC3_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 4uyg BROMODOMAIN-CONTAINI
NG PROTEIN 2
(Homo
sapiens) 		7 / 8 TRP A 370
PRO A 371
VAL A 376
LEU A 381
LEU A 383
ASN A 429
MET A 438
 None
None
73B  A1456 (-4.0A)
73B  A1456 (-4.9A)
73B  A1456 (-4.9A)
73B  A1456 (-3.3A)
73B  A1456 ( 3.8A)
 0.58A 3u5kC-4uygA:
17.6		 3u5kC-4uygA:
34.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U5K_D_08JD4_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 4uyg BROMODOMAIN-CONTAINI
NG PROTEIN 2
(Homo
sapiens) 		7 / 8 TRP A 370
PRO A 371
VAL A 376
LEU A 381
LEU A 383
ASN A 429
MET A 438
 None
None
73B  A1456 (-4.0A)
73B  A1456 (-4.9A)
73B  A1456 (-4.9A)
73B  A1456 (-3.3A)
73B  A1456 ( 3.8A)
 0.65A 3u5kD-4uygA:
18.0		 3u5kD-4uygA:
34.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A9J_A_TYLA1188_1
(BROMODOMAIN
CONTAINING 2)		 4uyg BROMODOMAIN-CONTAINI
NG PROTEIN 2
(Homo
sapiens) 		4 / 5 VAL A 376
LEU A 381
LEU A 383
ASN A 429
 73B  A1456 (-4.0A)
73B  A1456 (-4.9A)
73B  A1456 (-4.9A)
73B  A1456 (-3.3A)
 0.34A 4a9jA-4uygA:
19.3		 4a9jA-4uygA:
48.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A9J_B_TYLB1187_1
(BROMODOMAIN
CONTAINING 2)		 4uyg BROMODOMAIN-CONTAINI
NG PROTEIN 2
(Homo
sapiens) 		4 / 5 VAL A 376
LEU A 381
LEU A 383
ASN A 429
 73B  A1456 (-4.0A)
73B  A1456 (-4.9A)
73B  A1456 (-4.9A)
73B  A1456 (-3.3A)
 0.36A 4a9jB-4uygA:
19.2		 4a9jB-4uygA:
48.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A9J_C_TYLC1184_1
(BROMODOMAIN
CONTAINING 2)		 4uyg BROMODOMAIN-CONTAINI
NG PROTEIN 2
(Homo
sapiens) 		4 / 5 VAL A 376
LEU A 381
LEU A 383
ASN A 429
 73B  A1456 (-4.0A)
73B  A1456 (-4.9A)
73B  A1456 (-4.9A)
73B  A1456 (-3.3A)
 0.36A 4a9jC-4uygA:
19.5		 4a9jC-4uygA:
48.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A9K_A_TYLA2200_1
(CREB-BINDING PROTEIN)		 4uyg BROMODOMAIN-CONTAINI
NG PROTEIN 2
(Homo
sapiens) 		5 / 6 VAL A 376
LEU A 381
TYR A 428
ASN A 429
VAL A 435
 73B  A1456 (-4.0A)
73B  A1456 (-4.9A)
None
73B  A1456 (-3.3A)
73B  A1456 (-4.1A)
 0.52A 4a9kA-4uygA:
17.8		 4a9kA-4uygA:
31.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A9K_B_TYLB2198_1
(CREB-BINDING PROTEIN)		 4uyg BROMODOMAIN-CONTAINI
NG PROTEIN 2
(Homo
sapiens) 		4 / 5 VAL A 376
LEU A 381
ASN A 429
VAL A 435
 73B  A1456 (-4.0A)
73B  A1456 (-4.9A)
73B  A1456 (-3.3A)
73B  A1456 (-4.1A)
 0.61A 4a9kB-4uygA:
18.0		 4a9kB-4uygA:
31.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4C66_A_H4CA1168_0
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 4uyg BROMODOMAIN-CONTAINI
NG PROTEIN 2
(Homo
sapiens) 		7 / 9 TRP A 370
PRO A 371
VAL A 376
LEU A 381
LEU A 383
ASN A 429
MET A 438
 None
None
73B  A1456 (-4.0A)
73B  A1456 (-4.9A)
73B  A1456 (-4.9A)
73B  A1456 (-3.3A)
73B  A1456 ( 3.8A)
 0.43A 4c66A-4uygA:
18.0		 4c66A-4uygA:
35.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5PBE_A_TYLA2001_1
(BROMODOMAIN ADJACENT
TO ZINC FINGER
DOMAIN PROTEIN 2B)		 4uyg BROMODOMAIN-CONTAINI
NG PROTEIN 2
(Homo
sapiens) 		4 / 6 PRO A 371
VAL A 376
TYR A 386
ASN A 429
 None
73B  A1456 (-4.0A)
None
73B  A1456 (-3.3A)
 0.66A 5pbeA-4uygA:
16.7		 5pbeA-4uygA:
38.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Y1Y_A_HNQA201_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 4uyg BROMODOMAIN-CONTAINI
NG PROTEIN 2
(Homo
sapiens) 		7 / 8 PRO A 371
VAL A 376
LEU A 381
LEU A 383
CYH A 425
TYR A 428
ASN A 429
 None
73B  A1456 (-4.0A)
73B  A1456 (-4.9A)
73B  A1456 (-4.9A)
73B  A1456 (-3.3A)
None
73B  A1456 (-3.3A)
 0.48A 5y1yA-4uygA:
17.9		 5y1yA-4uygA:
35.03