SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '71T'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y4L_B_SVRB301_1
(PHOSPHOLIPASE A2
HOMOLOG 2)		 5syn ACYL-PROTEIN
THIOESTERASE 2
(Homo
sapiens) 		5 / 12 LEU A  78
GLY A  34
GLY A  32
LEU A  30
GLY A 120
 71T  A 301 ( 3.7A)
None
None
None
None
 0.87A 1y4lA-5synA:
undetectable		 1y4lA-5synA:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J14_A_X2NA602_1
(CHOLESTEROL
24-HYDROXYLASE)		 5syn ACYL-PROTEIN
THIOESTERASE 2
(Homo
sapiens) 		5 / 10 ALA A 159
LEU A 133
ALA A 144
ALA A 188
THR A 187
 None
None
None
None
71T  A 301 (-3.3A)
 1.02A 4j14A-5synA:
undetectable		 4j14A-5synA:
20.78