SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6ZL'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1GSE_A_EAAA224_1 (GLUTATHIONE TRANSFERASE)	5l26	NUCLEOSIDE PERMEASE (Neisseria wadsworthii)	5 / 12	ARG A 53 GLY A 52 LEU A 45 LEU A 42 ALA A 59	None None None 6ZL A 502 (-4.4A) 6ZL A 504 ( 4.1A)	1.17A	1gseA-5l26A: undetectable	1gseA-5l26A: 19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RXC_I_URFI2041_1 (URIDINE PHOSPHORYLASE)	5l26	NUCLEOSIDE PERMEASE (Neisseria wadsworthii)	4 / 8	GLY A 130 MET A 135 ILE A 128 VAL A 127	None None 6ZL A 502 ( 4.7A) 6ZL A 502 (-4.4A)	0.98A	1rxcI-5l26A: undetectable	1rxcI-5l26A: 20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3C6G_A_VD3A701_1 (CYTOCHROME P450 2R1)	5l26	NUCLEOSIDE PERMEASE (Neisseria wadsworthii)	5 / 12	ALA A 367 ALA A 205 GLY A 186 THR A 155 VAL A 374	None None 6ZL A 501 ( 4.4A) URI A 505 ( 4.5A) URI A 505 (-4.6A)	1.05A	3c6gA-5l26A: undetectable	3c6gA-5l26A: 22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3C6G_B_VD3B700_1 (CYTOCHROME P450 2R1)	5l26	NUCLEOSIDE PERMEASE (Neisseria wadsworthii)	5 / 12	ALA A 367 ALA A 205 GLY A 186 THR A 155 VAL A 374	None None 6ZL A 501 ( 4.4A) URI A 505 ( 4.5A) URI A 505 (-4.6A)	1.09A	3c6gB-5l26A: undetectable	3c6gB-5l26A: 22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KVV_A_URFA254_1 (URIDINE PHOSPHORYLASE)	5l26	NUCLEOSIDE PERMEASE (Neisseria wadsworthii)	4 / 6	GLY A 130 MET A 135 ILE A 128 VAL A 127	None None 6ZL A 502 ( 4.7A) 6ZL A 502 (-4.4A)	1.03A	3kvvA-5l26A: undetectable	3kvvA-5l26A: 20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KVV_C_URFC254_1 (URIDINE PHOSPHORYLASE)	5l26	NUCLEOSIDE PERMEASE (Neisseria wadsworthii)	4 / 6	GLY A 130 MET A 135 ILE A 128 VAL A 127	None None 6ZL A 502 ( 4.7A) 6ZL A 502 (-4.4A)	1.00A	3kvvC-5l26A: undetectable	3kvvC-5l26A: 20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KVV_E_URFE254_1 (URIDINE PHOSPHORYLASE)	5l26	NUCLEOSIDE PERMEASE (Neisseria wadsworthii)	4 / 6	GLY A 130 MET A 135 ILE A 128 VAL A 127	None None 6ZL A 502 ( 4.7A) 6ZL A 502 (-4.4A)	1.01A	3kvvE-5l26A: undetectable	3kvvE-5l26A: 20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KVV_F_URFF254_1 (URIDINE PHOSPHORYLASE)	5l26	NUCLEOSIDE PERMEASE (Neisseria wadsworthii)	4 / 6	GLY A 130 MET A 135 ILE A 128 VAL A 127	None None 6ZL A 502 ( 4.7A) 6ZL A 502 (-4.4A)	0.99A	3kvvF-5l26A: undetectable	3kvvF-5l26A: 20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QYN_B_RTLB201_0 (RETINOL-BINDING PROTEIN 2)	5l26	NUCLEOSIDE PERMEASE (Neisseria wadsworthii)	5 / 12	ILE A 125 THR A 62 LEU A 124 LEU A 111 LEU A 115	None 6ZL A 504 (-3.8A) None None None	1.26A	4qynB-5l26A: undetectable	4qynB-5l26A: 15.30

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1GSE_A_EAAA224_1","GLUTATHIONE TRANSFERASE","5l26","NUCLEOSIDE PERMEASE","Neisseria wadsworthii",5,"ARG A  53;GLY A  52;LEU A  45;LEU A  42;ALA A  59","None;None;None;6ZL A 502 (-4.4A);6ZL A 504 ( 4.1A)","1.17A","1gseA-5l26A:undetectable",null],["1RXC_I_URFI2041_1","URIDINE PHOSPHORYLASE","5l26","NUCLEOSIDE PERMEASE","Neisseria wadsworthii",4,"GLY A 130;MET A 135;ILE A 128;VAL A 127","None;None;6ZL A 502 ( 4.7A);6ZL A 502 (-4.4A)","0.98A","1rxcI-5l26A:undetectable","1gseA-5l26A:19.20"],["3C6G_A_VD3A701_1","CYTOCHROME P450 2R1","5l26","NUCLEOSIDE PERMEASE","Neisseria wadsworthii",5,"ALA A 367;ALA A 205;GLY A 186;THR A 155;VAL A 374","None;None;6ZL A 501 ( 4.4A);URI A 505 ( 4.5A);URI A 505 (-4.6A)","1.05A","3c6gA-5l26A:undetectable","1rxcI-5l26A:20.88"],["3C6G_B_VD3B700_1","CYTOCHROME P450 2R1","5l26","NUCLEOSIDE PERMEASE","Neisseria wadsworthii",5,"ALA A 367;ALA A 205;GLY A 186;THR A 155;VAL A 374","None;None;6ZL A 501 ( 4.4A);URI A 505 ( 4.5A);URI A 505 (-4.6A)","1.09A","3c6gB-5l26A:undetectable","3c6gA-5l26A:22.60"],["3KVV_A_URFA254_1","URIDINE PHOSPHORYLASE","5l26","NUCLEOSIDE PERMEASE","Neisseria wadsworthii",4,"GLY A 130;MET A 135;ILE A 128;VAL A 127","None;None;6ZL A 502 ( 4.7A);6ZL A 502 (-4.4A)","1.03A","3kvvA-5l26A:undetectable","3c6gB-5l26A:22.60"],["3KVV_C_URFC254_1","URIDINE PHOSPHORYLASE","5l26","NUCLEOSIDE PERMEASE","Neisseria wadsworthii",4,"GLY A 130;MET A 135;ILE A 128;VAL A 127","None;None;6ZL A 502 ( 4.7A);6ZL A 502 (-4.4A)","1.00A","3kvvC-5l26A:undetectable","3kvvA-5l26A:20.88"],["3KVV_E_URFE254_1","URIDINE PHOSPHORYLASE","5l26","NUCLEOSIDE PERMEASE","Neisseria wadsworthii",4,"GLY A 130;MET A 135;ILE A 128;VAL A 127","None;None;6ZL A 502 ( 4.7A);6ZL A 502 (-4.4A)","1.01A","3kvvE-5l26A:undetectable","3kvvC-5l26A:20.88"],["3KVV_F_URFF254_1","URIDINE PHOSPHORYLASE","5l26","NUCLEOSIDE PERMEASE","Neisseria wadsworthii",4,"GLY A 130;MET A 135;ILE A 128;VAL A 127","None;None;6ZL A 502 ( 4.7A);6ZL A 502 (-4.4A)","0.99A","3kvvF-5l26A:undetectable","3kvvE-5l26A:20.88"],["4QYN_B_RTLB201_0","RETINOL-BINDING PROTEIN 2","5l26","NUCLEOSIDE PERMEASE","Neisseria wadsworthii",5,"ILE A 125;THR A  62;LEU A 124;LEU A 111;LEU A 115","None;6ZL A 504 (-3.8A);None;None;None","1.26A","4qynB-5l26A:undetectable","3kvvF-5l26A:20.88"]]