SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6UY'
DrReposER ID / Desc. | Hit PDBID |
Hit Macromolecule |
Res. Matches |
Interface | HETATM | RMSD | Dali Z-score |
Seq. Identity (%) |
View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1UWH_A_BAXA1723_1 (B-RAF PROTO-ONCOGENESERINE/THREONINE-PROTEIN KINASE) |
5ko1 | MIXED LINEAGE KINASEDOMAIN-LIKE PROTEIN (Homosapiens) | 6 / 12 | ALA A 228GLU A 250LEU A 263CYH A 286LEU A 320HIS A 329 | 6UY A 501 (-3.4A)6UY A 501 (-4.3A)None6UY A 501 (-4.3A)NoneNone | 0.93A | 1uwhA-5ko1A:26.9 | 1uwhA-5ko1A:26.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1UWH_B_BAXB1723_1 (B-RAF PROTO-ONCOGENESERINE/THREONINE-PROTEIN KINASE) |
5ko1 | MIXED LINEAGE KINASEDOMAIN-LIKE PROTEIN (Homosapiens) | 7 / 12 | ALA A 228LYS A 230GLU A 250LEU A 263CYH A 286LEU A 320HIS A 329 | 6UY A 501 (-3.4A)6UY A 501 (-4.0A)6UY A 501 (-4.3A)None6UY A 501 (-4.3A)NoneNone | 0.88A | 1uwhB-5ko1A:26.8 | 1uwhB-5ko1A:26.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1UWJ_A_BAXA1723_1 (B-RAF PROTO-ONCOGENESERINE/THREONINE-PROTEIN KINASE) |
5ko1 | MIXED LINEAGE KINASEDOMAIN-LIKE PROTEIN (Homosapiens) | 6 / 12 | ALA A 228GLU A 250LEU A 263CYH A 286LEU A 320HIS A 329 | 6UY A 501 (-3.4A)6UY A 501 (-4.3A)None6UY A 501 (-4.3A)NoneNone | 0.93A | 1uwjA-5ko1A:8.6 | 1uwjA-5ko1A:26.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1UWJ_B_BAXB1723_1 (B-RAF PROTO-ONCOGENESERINE/THREONINE-PROTEIN KINASE) |
5ko1 | MIXED LINEAGE KINASEDOMAIN-LIKE PROTEIN (Homosapiens) | 6 / 12 | ALA A 228GLU A 250LEU A 263CYH A 286LEU A 320HIS A 329 | 6UY A 501 (-3.4A)6UY A 501 (-4.3A)None6UY A 501 (-4.3A)NoneNone | 0.92A | 1uwjB-5ko1A:8.6 | 1uwjB-5ko1A:26.16 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2GQG_A_1N1A501_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1) |
5ko1 | MIXED LINEAGE KINASEDOMAIN-LIKE PROTEIN (Homosapiens) | 7 / 12 | LEU A 209ALA A 228LYS A 230GLU A 250GLY A 289LEU A 338ALA A 348 | None6UY A 501 (-3.4A)6UY A 501 (-4.0A)6UY A 501 (-4.3A)6UY A 501 ( 4.3A)6UY A 501 (-4.5A)6UY A 501 (-3.4A) | 0.76A | 2gqgA-5ko1A:26.8 | 2gqgA-5ko1A:30.39 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2GQG_A_1N1A501_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1) |
5ko1 | MIXED LINEAGE KINASEDOMAIN-LIKE PROTEIN (Homosapiens) | 8 / 12 | LEU A 209ALA A 228LYS A 230GLU A 250MET A 254ILE A 281GLY A 289LEU A 338 | None6UY A 501 (-3.4A)6UY A 501 (-4.0A)6UY A 501 (-4.3A)NoneNone6UY A 501 ( 4.3A)6UY A 501 (-4.5A) | 0.74A | 2gqgA-5ko1A:26.8 | 2gqgA-5ko1A:30.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2Y6O_A_1N1A1892_1 (EPHRIN TYPE-ARECEPTOR 4) |
5ko1 | MIXED LINEAGE KINASEDOMAIN-LIKE PROTEIN (Homosapiens) | 8 / 12 | ALA A 228LYS A 230GLU A 250MET A 254ILE A 281TYR A 285GLY A 289LEU A 338 | 6UY A 501 (-3.4A)6UY A 501 (-4.0A)6UY A 501 (-4.3A)NoneNone6UY A 501 ( 4.8A)6UY A 501 ( 4.3A)6UY A 501 (-4.5A) | 0.64A | 2y6oA-5ko1A:28.2 | 2y6oA-5ko1A:28.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ZVA_A_1N1A513_1 (TYROSINE-PROTEINKINASE LYN) |
5ko1 | MIXED LINEAGE KINASEDOMAIN-LIKE PROTEIN (Homosapiens) | 8 / 12 | LEU A 209ALA A 228LYS A 230GLU A 250MET A 254ILE A 281GLY A 289LEU A 338 | None6UY A 501 (-3.4A)6UY A 501 (-4.0A)6UY A 501 (-4.3A)NoneNone6UY A 501 ( 4.3A)6UY A 501 (-4.5A) | 0.81A | 2zvaA-5ko1A:28.1 | 2zvaA-5ko1A:28.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3AOC_C_ERYC3402_0 (ACRIFLAVINERESISTANCE PROTEIN B) |
5ko1 | MIXED LINEAGE KINASEDOMAIN-LIKE PROTEIN (Homosapiens) | 5 / 12 | MET A 283PHE A 232ILE A 281LEU A 317GLU A 327 | 6UY A 501 (-3.8A)NoneNoneNoneNone | 1.26A | 3aocC-5ko1A:undetectable | 3aocC-5ko1A:15.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3K54_A_1N1A1_1 (TYROSINE-PROTEINKINASE BTK) |
5ko1 | MIXED LINEAGE KINASEDOMAIN-LIKE PROTEIN (Homosapiens) | 9 / 12 | LEU A 209ALA A 228LYS A 230GLU A 250MET A 254ILE A 281TYR A 285GLY A 289LEU A 338 | None6UY A 501 (-3.4A)6UY A 501 (-4.0A)6UY A 501 (-4.3A)NoneNone6UY A 501 ( 4.8A)6UY A 501 ( 4.3A)6UY A 501 (-4.5A) | 0.83A | 3k54A-5ko1A:27.4 | 3k54A-5ko1A:27.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3OG7_A_032A1_1 (AKAP9-BRAF FUSIONPROTEIN) |
5ko1 | MIXED LINEAGE KINASEDOMAIN-LIKE PROTEIN (Homosapiens) | 5 / 12 | ALA A 228LYS A 230LEU A 263CYH A 286PHE A 350 | 6UY A 501 (-3.4A)6UY A 501 (-4.0A)None6UY A 501 (-4.3A)None | 0.79A | 3og7A-5ko1A:26.1 | 3og7A-5ko1A:26.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ZBF_A_VGHA3000_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE ROS) |
5ko1 | MIXED LINEAGE KINASEDOMAIN-LIKE PROTEIN (Homosapiens) | 5 / 12 | LEU A 209ALA A 228LEU A 263GLY A 289LEU A 338 | None6UY A 501 (-3.4A)None6UY A 501 ( 4.3A)6UY A 501 (-4.5A) | 0.38A | 3zbfA-5ko1A:28.2 | 3zbfA-5ko1A:28.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4C8B_A_0LIA1000_1 (RECEPTOR-INTERACTINGSERINE/THREONINE-PROTEIN KINASE 2) |
5ko1 | MIXED LINEAGE KINASEDOMAIN-LIKE PROTEIN (Homosapiens) | 7 / 12 | ALA A 228LYS A 230LEU A 263ILE A 281HIS A 329LEU A 338ALA A 348 | 6UY A 501 (-3.4A)6UY A 501 (-4.0A)NoneNoneNone6UY A 501 (-4.5A)6UY A 501 (-3.4A) | 0.73A | 4c8bA-5ko1A:27.3 | 4c8bA-5ko1A:28.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4C8B_B_0LIB1000_1 (RECEPTOR-INTERACTINGSERINE/THREONINE-PROTEIN KINASE 2) |
5ko1 | MIXED LINEAGE KINASEDOMAIN-LIKE PROTEIN (Homosapiens) | 7 / 12 | ALA A 228LYS A 230ILE A 262LEU A 263HIS A 329LEU A 338ALA A 348 | 6UY A 501 (-3.4A)6UY A 501 (-4.0A)NoneNoneNone6UY A 501 (-4.5A)6UY A 501 (-3.4A) | 0.67A | 4c8bB-5ko1A:27.1 | 4c8bB-5ko1A:28.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4MXO_A_DB8A601_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE SRC) |
5ko1 | MIXED LINEAGE KINASEDOMAIN-LIKE PROTEIN (Homosapiens) | 8 / 12 | LEU A 209ALA A 228LYS A 230GLU A 250MET A 254ILE A 281TYR A 285GLY A 289 | None6UY A 501 (-3.4A)6UY A 501 (-4.0A)6UY A 501 (-4.3A)NoneNone6UY A 501 ( 4.8A)6UY A 501 ( 4.3A) | 0.58A | 4mxoA-5ko1A:27.1 | 4mxoA-5ko1A:26.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4MXO_B_DB8B601_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE SRC) |
5ko1 | MIXED LINEAGE KINASEDOMAIN-LIKE PROTEIN (Homosapiens) | 8 / 12 | LEU A 209ALA A 228LYS A 230GLU A 250ILE A 281TYR A 285GLY A 289LEU A 338 | None6UY A 501 (-3.4A)6UY A 501 (-4.0A)6UY A 501 (-4.3A)None6UY A 501 ( 4.8A)6UY A 501 ( 4.3A)6UY A 501 (-4.5A) | 0.67A | 4mxoB-5ko1A:27.5 | 4mxoB-5ko1A:26.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4MXX_A_DB8A601_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE SRC) |
5ko1 | MIXED LINEAGE KINASEDOMAIN-LIKE PROTEIN (Homosapiens) | 7 / 12 | LEU A 209ALA A 228LYS A 230GLU A 250ILE A 281TYR A 285GLY A 289 | None6UY A 501 (-3.4A)6UY A 501 (-4.0A)6UY A 501 (-4.3A)None6UY A 501 ( 4.8A)6UY A 501 ( 4.3A) | 0.76A | 4mxxA-5ko1A:27.3 | 4mxxA-5ko1A:26.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4MXX_A_DB8A601_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE SRC) |
5ko1 | MIXED LINEAGE KINASEDOMAIN-LIKE PROTEIN (Homosapiens) | 7 / 12 | LEU A 209ALA A 228LYS A 230GLU A 250MET A 254TYR A 285GLY A 289 | None6UY A 501 (-3.4A)6UY A 501 (-4.0A)6UY A 501 (-4.3A)None6UY A 501 ( 4.8A)6UY A 501 ( 4.3A) | 0.75A | 4mxxA-5ko1A:27.3 | 4mxxA-5ko1A:26.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4MXX_A_DB8A601_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE SRC) |
5ko1 | MIXED LINEAGE KINASEDOMAIN-LIKE PROTEIN (Homosapiens) | 7 / 12 | LEU A 209ALA A 228LYS A 230MET A 254TYR A 285GLY A 289LEU A 338 | None6UY A 501 (-3.4A)6UY A 501 (-4.0A)None6UY A 501 ( 4.8A)6UY A 501 ( 4.3A)6UY A 501 (-4.5A) | 0.74A | 4mxxA-5ko1A:27.3 | 4mxxA-5ko1A:26.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4MXY_A_DB8A601_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE SRC) |
5ko1 | MIXED LINEAGE KINASEDOMAIN-LIKE PROTEIN (Homosapiens) | 8 / 12 | LEU A 209ALA A 228GLU A 250ILE A 281MET A 283TYR A 285GLY A 289LEU A 338 | None6UY A 501 (-3.4A)6UY A 501 (-4.3A)None6UY A 501 (-3.8A)6UY A 501 ( 4.8A)6UY A 501 ( 4.3A)6UY A 501 (-4.5A) | 0.85A | 4mxyA-5ko1A:27.5 | 4mxyA-5ko1A:26.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4MXY_A_DB8A601_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE SRC) |
5ko1 | MIXED LINEAGE KINASEDOMAIN-LIKE PROTEIN (Homosapiens) | 8 / 12 | LEU A 209ALA A 228LYS A 230ILE A 281MET A 283TYR A 285GLY A 289LEU A 338 | None6UY A 501 (-3.4A)6UY A 501 (-4.0A)None6UY A 501 (-3.8A)6UY A 501 ( 4.8A)6UY A 501 ( 4.3A)6UY A 501 (-4.5A) | 0.75A | 4mxyA-5ko1A:27.5 | 4mxyA-5ko1A:26.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4MXZ_A_DB8A601_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE SRC) |
5ko1 | MIXED LINEAGE KINASEDOMAIN-LIKE PROTEIN (Homosapiens) | 8 / 12 | LEU A 209ALA A 228GLU A 250ILE A 281MET A 283TYR A 285GLY A 289LEU A 338 | None6UY A 501 (-3.4A)6UY A 501 (-4.3A)None6UY A 501 (-3.8A)6UY A 501 ( 4.8A)6UY A 501 ( 4.3A)6UY A 501 (-4.5A) | 0.85A | 4mxzA-5ko1A:27.5 | 4mxzA-5ko1A:26.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4MXZ_A_DB8A601_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE SRC) |
5ko1 | MIXED LINEAGE KINASEDOMAIN-LIKE PROTEIN (Homosapiens) | 8 / 12 | LEU A 209ALA A 228LYS A 230ILE A 281MET A 283TYR A 285GLY A 289LEU A 338 | None6UY A 501 (-3.4A)6UY A 501 (-4.0A)None6UY A 501 (-3.8A)6UY A 501 ( 4.8A)6UY A 501 ( 4.3A)6UY A 501 (-4.5A) | 0.75A | 4mxzA-5ko1A:27.5 | 4mxzA-5ko1A:26.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4U0I_A_0LIA1001_2 (MAST/STEM CELLGROWTH FACTORRECEPTORKIT,MAST/STEM CELLGROWTH FACTORRECEPTOR KIT) |
5ko1 | MIXED LINEAGE KINASEDOMAIN-LIKE PROTEIN (Homosapiens) | 6 / 12 | ALA A 228LYS A 230CYH A 286GLY A 289HIS A 329LEU A 338 | 6UY A 501 (-3.4A)6UY A 501 (-4.0A)6UY A 501 (-4.3A)6UY A 501 ( 4.3A)None6UY A 501 (-4.5A) | 0.51A | 4u0iA-5ko1A:26.7 | 4u0iA-5ko1A:26.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4WA9_A_AXIA9000_1 (TYROSINE-PROTEINKINASE ABL1) |
5ko1 | MIXED LINEAGE KINASEDOMAIN-LIKE PROTEIN (Homosapiens) | 6 / 11 | LEU A 209ALA A 228GLY A 289ASN A 336LEU A 338ALA A 348 | None6UY A 501 (-3.4A)6UY A 501 ( 4.3A)6UY A 501 (-4.4A)6UY A 501 (-4.5A)6UY A 501 (-3.4A) | 0.62A | 4wa9A-5ko1A:23.2 | 4wa9A-5ko1A:29.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4WBO_C_ANWC601_0 (RHODOPSIN KINASE) |
5ko1 | MIXED LINEAGE KINASEDOMAIN-LIKE PROTEIN (Homosapiens) | 4 / 6 | LEU A 209ALA A 228MET A 283LEU A 338 | None6UY A 501 (-3.4A)6UY A 501 (-3.8A)6UY A 501 (-4.5A) | 0.93A | 4wboC-5ko1A:20.7 | 4wboC-5ko1A:21.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4WKQ_A_IREA1101_1 (EPIDERMAL GROWTHFACTOR RECEPTOR) |
5ko1 | MIXED LINEAGE KINASEDOMAIN-LIKE PROTEIN (Homosapiens) | 7 / 12 | LEU A 209ALA A 228LYS A 230GLU A 250MET A 254GLY A 289LEU A 338 | None6UY A 501 (-3.4A)6UY A 501 (-4.0A)6UY A 501 (-4.3A)None6UY A 501 ( 4.3A)6UY A 501 (-4.5A) | 0.83A | 4wkqA-5ko1A:26.2 | 4wkqA-5ko1A:26.04 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4XLI_B_1N1B600_1 (NON-SPECIFICPROTEIN-TYROSINEKINASE) |
5ko1 | MIXED LINEAGE KINASEDOMAIN-LIKE PROTEIN (Homosapiens) | 8 / 12 | ALA A 228LYS A 230GLU A 250MET A 254ILE A 281TYR A 285GLY A 289LEU A 338 | 6UY A 501 (-3.4A)6UY A 501 (-4.0A)6UY A 501 (-4.3A)NoneNone6UY A 501 ( 4.8A)6UY A 501 ( 4.3A)6UY A 501 (-4.5A) | 0.70A | 4xliB-5ko1A:27.3 | 4xliB-5ko1A:30.41 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4XLI_B_1N1B600_1 (NON-SPECIFICPROTEIN-TYROSINEKINASE) |
5ko1 | MIXED LINEAGE KINASEDOMAIN-LIKE PROTEIN (Homosapiens) | 8 / 12 | LEU A 209ALA A 228LYS A 230GLU A 250MET A 254ILE A 281TYR A 285GLY A 289 | None6UY A 501 (-3.4A)6UY A 501 (-4.0A)6UY A 501 (-4.3A)NoneNone6UY A 501 ( 4.8A)6UY A 501 ( 4.3A) | 0.66A | 4xliB-5ko1A:27.3 | 4xliB-5ko1A:30.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4XV2_B_P06B801_1 (SERINE/THREONINE-PROTEIN KINASE B-RAF) |
5ko1 | MIXED LINEAGE KINASEDOMAIN-LIKE PROTEIN (Homosapiens) | 5 / 12 | ALA A 228LYS A 230LEU A 263CYH A 286PHE A 350 | 6UY A 501 (-3.4A)6UY A 501 (-4.0A)None6UY A 501 (-4.3A)None | 0.78A | 4xv2B-5ko1A:26.1 | 4xv2B-5ko1A:26.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5CSW_A_P06A801_1 (SERINE/THREONINE-PROTEIN KINASE B-RAF) |
5ko1 | MIXED LINEAGE KINASEDOMAIN-LIKE PROTEIN (Homosapiens) | 5 / 12 | ALA A 228LYS A 230LEU A 263CYH A 286PHE A 350 | 6UY A 501 (-3.4A)6UY A 501 (-4.0A)None6UY A 501 (-4.3A)None | 0.85A | 5cswA-5ko1A:25.3 | 5cswA-5ko1A:26.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5CSW_B_P06B801_1 (SERINE/THREONINE-PROTEIN KINASE B-RAF) |
5ko1 | MIXED LINEAGE KINASEDOMAIN-LIKE PROTEIN (Homosapiens) | 5 / 12 | ALA A 228LYS A 230LEU A 263CYH A 286PHE A 350 | 6UY A 501 (-3.4A)6UY A 501 (-4.0A)None6UY A 501 (-4.3A)None | 0.84A | 5cswB-5ko1A:25.2 | 5cswB-5ko1A:26.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5H2U_C_1N1C501_1 (PROTEIN-TYROSINEKINASE 6) |
5ko1 | MIXED LINEAGE KINASEDOMAIN-LIKE PROTEIN (Homosapiens) | 5 / 12 | LEU A 209ALA A 228LEU A 263GLY A 289LEU A 338 | None6UY A 501 (-3.4A)None6UY A 501 ( 4.3A)6UY A 501 (-4.5A) | 0.68A | 5h2uC-5ko1A:24.9 | 5h2uC-5ko1A:28.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5HI2_A_BAXA801_1 (SERINE/THREONINE-PROTEIN KINASE B-RAF) |
5ko1 | MIXED LINEAGE KINASEDOMAIN-LIKE PROTEIN (Homosapiens) | 7 / 12 | ALA A 228LYS A 230GLU A 250LEU A 263CYH A 286LEU A 320HIS A 329 | 6UY A 501 (-3.4A)6UY A 501 (-4.0A)6UY A 501 (-4.3A)None6UY A 501 (-4.3A)NoneNone | 0.86A | 5hi2A-5ko1A:26.5 | 5hi2A-5ko1A:26.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5I9X_A_DB8A1001_1 (EPHRIN TYPE-ARECEPTOR 2) |
5ko1 | MIXED LINEAGE KINASEDOMAIN-LIKE PROTEIN (Homosapiens) | 7 / 12 | ALA A 228LYS A 230GLU A 250ILE A 281TYR A 285GLY A 289LEU A 338 | 6UY A 501 (-3.4A)6UY A 501 (-4.0A)6UY A 501 (-4.3A)None6UY A 501 ( 4.8A)6UY A 501 ( 4.3A)6UY A 501 (-4.5A) | 0.62A | 5i9xA-5ko1A:28.6 | 5i9xA-5ko1A:29.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5I9Y_A_1N1A1001_1 (EPHRIN TYPE-ARECEPTOR 2) |
5ko1 | MIXED LINEAGE KINASEDOMAIN-LIKE PROTEIN (Homosapiens) | 7 / 12 | ALA A 228LYS A 230GLU A 250MET A 254TYR A 285GLY A 289LEU A 338 | 6UY A 501 (-3.4A)6UY A 501 (-4.0A)6UY A 501 (-4.3A)None6UY A 501 ( 4.8A)6UY A 501 ( 4.3A)6UY A 501 (-4.5A) | 0.61A | 5i9yA-5ko1A:28.6 | 5i9yA-5ko1A:29.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5W5V_A_ANWA701_0 (SERINE/THREONINE-PROTEIN KINASE TBK1) |
5ko1 | MIXED LINEAGE KINASEDOMAIN-LIKE PROTEIN (Homosapiens) | 5 / 9 | LEU A 209ALA A 228MET A 283CYH A 286GLY A 289 | None6UY A 501 (-3.4A)6UY A 501 (-3.8A)6UY A 501 (-4.3A)6UY A 501 ( 4.3A) | 0.86A | 5w5vA-5ko1A:13.9 | 5w5vA-5ko1A:17.71 |