SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6UI'
DrReposER ID / Desc. | Hit PDBID |
Hit Macromolecule |
Res. Matches |
Interface | HETATM | RMSD | Dali Z-score |
Seq. Identity (%) |
View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1IEP_A_STIA201_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL) |
4usf | STE20-LIKESERINE/THREONINE-PROTEIN KINASE (Homosapiens) | 7 / 12 | LEU A 40VAL A 48ALA A 61PHE A 110GLY A 114LEU A 162ALA A 172 | 6UI A 700 ( 4.9A)None6UI A 700 (-3.3A)6UI A 700 (-4.3A)6UI A 700 ( 4.2A)6UI A 700 (-4.2A)6UI A 700 ( 4.1A) | 0.95A | 1iepA-4usfA:18.8 | 1iepA-4usfA:28.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1IEP_A_STIA201_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL) |
4usf | STE20-LIKESERINE/THREONINE-PROTEIN KINASE (Homosapiens) | 7 / 12 | VAL A 48ALA A 61PHE A 110GLY A 114LEU A 162ALA A 172ASP A 173 | None6UI A 700 (-3.3A)6UI A 700 (-4.3A)6UI A 700 ( 4.2A)6UI A 700 (-4.2A)6UI A 700 ( 4.1A)None | 1.14A | 1iepA-4usfA:18.8 | 1iepA-4usfA:28.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1IEP_B_STIB202_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL) |
4usf | STE20-LIKESERINE/THREONINE-PROTEIN KINASE (Homosapiens) | 7 / 12 | LEU A 40VAL A 48ALA A 61PHE A 110GLY A 114ALA A 172ASP A 173 | 6UI A 700 ( 4.9A)None6UI A 700 (-3.3A)6UI A 700 (-4.3A)6UI A 700 ( 4.2A)6UI A 700 ( 4.1A)None | 1.16A | 1iepB-4usfA:18.9 | 1iepB-4usfA:28.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1XBB_A_STIA1_1 (TYROSINE-PROTEINKINASE SYK) |
4usf | STE20-LIKESERINE/THREONINE-PROTEIN KINASE (Homosapiens) | 5 / 9 | LEU A 40VAL A 48ALA A 61GLY A 114LEU A 162 | 6UI A 700 ( 4.9A)None6UI A 700 (-3.3A)6UI A 700 ( 4.2A)6UI A 700 (-4.2A) | 0.41A | 1xbbA-4usfA:23.6 | 1xbbA-4usfA:24.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2GQG_A_1N1A501_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1) |
4usf | STE20-LIKESERINE/THREONINE-PROTEIN KINASE (Homosapiens) | 8 / 12 | LEU A 40ALA A 61VAL A 92ILE A 106PHE A 110GLY A 114LEU A 162ALA A 172 | 6UI A 700 ( 4.9A)6UI A 700 (-3.3A)None6UI A 700 (-3.5A)6UI A 700 (-4.3A)6UI A 700 ( 4.2A)6UI A 700 (-4.2A)6UI A 700 ( 4.1A) | 0.68A | 2gqgA-4usfA:17.9 | 2gqgA-4usfA:27.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2HYY_A_STIA600_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1) |
4usf | STE20-LIKESERINE/THREONINE-PROTEIN KINASE (Homosapiens) | 7 / 12 | VAL A 48ALA A 61PHE A 110GLY A 114LEU A 162ALA A 172ASP A 173 | None6UI A 700 (-3.3A)6UI A 700 (-4.3A)6UI A 700 ( 4.2A)6UI A 700 (-4.2A)6UI A 700 ( 4.1A)None | 1.10A | 2hyyA-4usfA:18.9 | 2hyyA-4usfA:28.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2HYY_B_STIB600_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1) |
4usf | STE20-LIKESERINE/THREONINE-PROTEIN KINASE (Homosapiens) | 7 / 12 | VAL A 48ALA A 61PHE A 110GLY A 114LEU A 162ALA A 172ASP A 173 | None6UI A 700 (-3.3A)6UI A 700 (-4.3A)6UI A 700 ( 4.2A)6UI A 700 (-4.2A)6UI A 700 ( 4.1A)None | 1.14A | 2hyyB-4usfA:18.8 | 2hyyB-4usfA:28.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2HYY_C_STIC600_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1) |
4usf | STE20-LIKESERINE/THREONINE-PROTEIN KINASE (Homosapiens) | 8 / 12 | VAL A 48ALA A 61VAL A 92PHE A 110GLY A 114LEU A 162ALA A 172ASP A 173 | None6UI A 700 (-3.3A)None6UI A 700 (-4.3A)6UI A 700 ( 4.2A)6UI A 700 (-4.2A)6UI A 700 ( 4.1A)None | 0.97A | 2hyyC-4usfA:25.0 | 2hyyC-4usfA:28.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2HYY_D_STID600_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1) |
4usf | STE20-LIKESERINE/THREONINE-PROTEIN KINASE (Homosapiens) | 6 / 12 | VAL A 48ALA A 61ILE A 106PHE A 110LEU A 162ALA A 172 | None6UI A 700 (-3.3A)6UI A 700 (-3.5A)6UI A 700 (-4.3A)6UI A 700 (-4.2A)6UI A 700 ( 4.1A) | 0.89A | 2hyyD-4usfA:18.8 | 2hyyD-4usfA:28.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2HYY_D_STID600_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1) |
4usf | STE20-LIKESERINE/THREONINE-PROTEIN KINASE (Homosapiens) | 6 / 12 | VAL A 48ALA A 61PHE A 110LEU A 162ALA A 172ASP A 173 | None6UI A 700 (-3.3A)6UI A 700 (-4.3A)6UI A 700 (-4.2A)6UI A 700 ( 4.1A)None | 1.11A | 2hyyD-4usfA:18.8 | 2hyyD-4usfA:28.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ZVA_A_1N1A513_1 (TYROSINE-PROTEINKINASE LYN) |
4usf | STE20-LIKESERINE/THREONINE-PROTEIN KINASE (Homosapiens) | 7 / 12 | LEU A 40ALA A 61VAL A 92ILE A 106GLY A 114LEU A 162ALA A 172 | 6UI A 700 ( 4.9A)6UI A 700 (-3.3A)None6UI A 700 (-3.5A)6UI A 700 ( 4.2A)6UI A 700 (-4.2A)6UI A 700 ( 4.1A) | 0.72A | 2zvaA-4usfA:19.2 | 2zvaA-4usfA:26.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3C7Q_A_XINA1172_1 (VASCULAR ENDOTHELIALGROWTH FACTORRECEPTOR 2) |
4usf | STE20-LIKESERINE/THREONINE-PROTEIN KINASE (Homosapiens) | 7 / 12 | LEU A 40GLY A 41ALA A 61PHE A 110CYH A 111GLY A 114LEU A 162 | 6UI A 700 ( 4.9A)None6UI A 700 (-3.3A)6UI A 700 (-4.3A)6UI A 700 (-4.2A)6UI A 700 ( 4.2A)6UI A 700 (-4.2A) | 1.15A | 3c7qA-4usfA:18.0 | 3c7qA-4usfA:27.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3CS9_A_NILA600_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1) |
4usf | STE20-LIKESERINE/THREONINE-PROTEIN KINASE (Homosapiens) | 5 / 10 | LEU A 40VAL A 48VAL A 92ILE A 106PHE A 110 | 6UI A 700 ( 4.9A)NoneNone6UI A 700 (-3.5A)6UI A 700 (-4.3A) | 0.75A | 3cs9A-4usfA:18.5 | 3cs9A-4usfA:28.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3CS9_B_NILB600_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1) |
4usf | STE20-LIKESERINE/THREONINE-PROTEIN KINASE (Homosapiens) | 5 / 12 | ALA A 61GLY A 114HIS A 153ALA A 172ASP A 173 | 6UI A 700 (-3.3A)6UI A 700 ( 4.2A)None6UI A 700 ( 4.1A)None | 0.83A | 3cs9B-4usfA:19.7 | 3cs9B-4usfA:28.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3CS9_C_NILC600_2 (PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1) |
4usf | STE20-LIKESERINE/THREONINE-PROTEIN KINASE (Homosapiens) | 5 / 9 | LEU A 40VAL A 48LYS A 63VAL A 92ILE A 106 | 6UI A 700 ( 4.9A)None6UI A 700 (-4.5A)None6UI A 700 (-3.5A) | 1.02A | 3cs9C-4usfA:24.4 | 3cs9C-4usfA:28.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3GVU_A_STIA1001_1 (TYROSINE-PROTEINKINASE ABL2) |
4usf | STE20-LIKESERINE/THREONINE-PROTEIN KINASE (Homosapiens) | 7 / 12 | LEU A 40VAL A 48ALA A 61VAL A 92LEU A 162ALA A 172ASP A 173 | 6UI A 700 ( 4.9A)None6UI A 700 (-3.3A)None6UI A 700 (-4.2A)6UI A 700 ( 4.1A)None | 0.93A | 3gvuA-4usfA:18.9 | 3gvuA-4usfA:28.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3IK3_A_0LIA1_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1) |
4usf | STE20-LIKESERINE/THREONINE-PROTEIN KINASE (Homosapiens) | 6 / 12 | ALA A 61VAL A 92HIS A 153LEU A 162ALA A 172ASP A 173 | 6UI A 700 (-3.3A)NoneNone6UI A 700 (-4.2A)6UI A 700 ( 4.1A)None | 0.72A | 3ik3A-4usfA:24.7 | 3ik3A-4usfA:29.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3IK3_B_0LIB2_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1) |
4usf | STE20-LIKESERINE/THREONINE-PROTEIN KINASE (Homosapiens) | 6 / 12 | ALA A 61VAL A 92HIS A 153LEU A 162ALA A 172ASP A 173 | 6UI A 700 (-3.3A)NoneNone6UI A 700 (-4.2A)6UI A 700 ( 4.1A)None | 0.73A | 3ik3B-4usfA:24.4 | 3ik3B-4usfA:29.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3K5V_A_STIA2_1 (TYROSINE-PROTEINKINASE ABL1) |
4usf | STE20-LIKESERINE/THREONINE-PROTEIN KINASE (Homosapiens) | 7 / 12 | VAL A 48ALA A 61PHE A 110GLY A 114LEU A 162ALA A 172ASP A 173 | None6UI A 700 (-3.3A)6UI A 700 (-4.3A)6UI A 700 ( 4.2A)6UI A 700 (-4.2A)6UI A 700 ( 4.1A)None | 1.15A | 3k5vA-4usfA:23.9 | 3k5vA-4usfA:28.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3K5V_B_STIB2_1 (TYROSINE-PROTEINKINASE ABL1) |
4usf | STE20-LIKESERINE/THREONINE-PROTEIN KINASE (Homosapiens) | 7 / 12 | VAL A 48ALA A 61PHE A 110GLY A 114LEU A 162ALA A 172ASP A 173 | None6UI A 700 (-3.3A)6UI A 700 (-4.3A)6UI A 700 ( 4.2A)6UI A 700 (-4.2A)6UI A 700 ( 4.1A)None | 1.11A | 3k5vB-4usfA:18.2 | 3k5vB-4usfA:28.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3MIY_B_B49B2_1 (TYROSINE-PROTEINKINASE ITK/TSK) |
4usf | STE20-LIKESERINE/THREONINE-PROTEIN KINASE (Homosapiens) | 5 / 9 | ALA A 61LYS A 63PHE A 110GLY A 114LEU A 162 | 6UI A 700 (-3.3A)6UI A 700 (-4.5A)6UI A 700 (-4.3A)6UI A 700 ( 4.2A)6UI A 700 (-4.2A) | 0.69A | 3miyB-4usfA:24.8 | 3miyB-4usfA:26.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3MS9_A_STIA1_1 (TYROSINE-PROTEINKINASE ABL1) |
4usf | STE20-LIKESERINE/THREONINE-PROTEIN KINASE (Homosapiens) | 6 / 12 | LEU A 40VAL A 48ALA A 61PHE A 110LEU A 162ALA A 172 | 6UI A 700 ( 4.9A)None6UI A 700 (-3.3A)6UI A 700 (-4.3A)6UI A 700 (-4.2A)6UI A 700 ( 4.1A) | 0.80A | 3ms9A-4usfA:18.9 | 3ms9A-4usfA:28.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3MS9_A_STIA1_1 (TYROSINE-PROTEINKINASE ABL1) |
4usf | STE20-LIKESERINE/THREONINE-PROTEIN KINASE (Homosapiens) | 6 / 12 | VAL A 48ALA A 61PHE A 110LEU A 162ALA A 172ASP A 173 | None6UI A 700 (-3.3A)6UI A 700 (-4.3A)6UI A 700 (-4.2A)6UI A 700 ( 4.1A)None | 1.11A | 3ms9A-4usfA:18.9 | 3ms9A-4usfA:28.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3MS9_B_STIB1_1 (TYROSINE-PROTEINKINASE ABL1) |
4usf | STE20-LIKESERINE/THREONINE-PROTEIN KINASE (Homosapiens) | 7 / 12 | LEU A 40VAL A 48ALA A 61PHE A 110GLY A 114LEU A 162ALA A 172 | 6UI A 700 ( 4.9A)None6UI A 700 (-3.3A)6UI A 700 (-4.3A)6UI A 700 ( 4.2A)6UI A 700 (-4.2A)6UI A 700 ( 4.1A) | 0.91A | 3ms9B-4usfA:18.8 | 3ms9B-4usfA:28.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3MS9_B_STIB1_1 (TYROSINE-PROTEINKINASE ABL1) |
4usf | STE20-LIKESERINE/THREONINE-PROTEIN KINASE (Homosapiens) | 7 / 12 | VAL A 48ALA A 61PHE A 110GLY A 114LEU A 162ALA A 172ASP A 173 | None6UI A 700 (-3.3A)6UI A 700 (-4.3A)6UI A 700 ( 4.2A)6UI A 700 (-4.2A)6UI A 700 ( 4.1A)None | 1.13A | 3ms9B-4usfA:18.8 | 3ms9B-4usfA:28.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3MSS_A_STIA1_1 (TYROSINE-PROTEINKINASE ABL1) |
4usf | STE20-LIKESERINE/THREONINE-PROTEIN KINASE (Homosapiens) | 6 / 12 | LEU A 40VAL A 48ALA A 61PHE A 110LEU A 162ALA A 172 | 6UI A 700 ( 4.9A)None6UI A 700 (-3.3A)6UI A 700 (-4.3A)6UI A 700 (-4.2A)6UI A 700 ( 4.1A) | 0.83A | 3mssA-4usfA:19.0 | 3mssA-4usfA:28.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3MSS_A_STIA1_1 (TYROSINE-PROTEINKINASE ABL1) |
4usf | STE20-LIKESERINE/THREONINE-PROTEIN KINASE (Homosapiens) | 6 / 12 | VAL A 48ALA A 61PHE A 110LEU A 162ALA A 172ASP A 173 | None6UI A 700 (-3.3A)6UI A 700 (-4.3A)6UI A 700 (-4.2A)6UI A 700 ( 4.1A)None | 1.11A | 3mssA-4usfA:19.0 | 3mssA-4usfA:28.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3MSS_C_STIC1_1 (TYROSINE-PROTEINKINASE ABL1) |
4usf | STE20-LIKESERINE/THREONINE-PROTEIN KINASE (Homosapiens) | 6 / 12 | LEU A 40VAL A 48ALA A 61PHE A 110LEU A 162ALA A 172 | 6UI A 700 ( 4.9A)None6UI A 700 (-3.3A)6UI A 700 (-4.3A)6UI A 700 (-4.2A)6UI A 700 ( 4.1A) | 0.83A | 3mssC-4usfA:19.0 | 3mssC-4usfA:28.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3MSS_C_STIC1_1 (TYROSINE-PROTEINKINASE ABL1) |
4usf | STE20-LIKESERINE/THREONINE-PROTEIN KINASE (Homosapiens) | 6 / 12 | VAL A 48ALA A 61PHE A 110LEU A 162ALA A 172ASP A 173 | None6UI A 700 (-3.3A)6UI A 700 (-4.3A)6UI A 700 (-4.2A)6UI A 700 ( 4.1A)None | 1.12A | 3mssC-4usfA:19.0 | 3mssC-4usfA:28.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3MSS_D_STID1_1 (TYROSINE-PROTEINKINASE ABL1) |
4usf | STE20-LIKESERINE/THREONINE-PROTEIN KINASE (Homosapiens) | 6 / 12 | ALA A 61PHE A 110GLY A 114LEU A 162ALA A 172ASP A 173 | 6UI A 700 (-3.3A)6UI A 700 (-4.3A)6UI A 700 ( 4.2A)6UI A 700 (-4.2A)6UI A 700 ( 4.1A)None | 0.91A | 3mssD-4usfA:19.0 | 3mssD-4usfA:28.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3MSS_D_STID1_1 (TYROSINE-PROTEINKINASE ABL1) |
4usf | STE20-LIKESERINE/THREONINE-PROTEIN KINASE (Homosapiens) | 6 / 12 | LEU A 40ALA A 61PHE A 110GLY A 114LEU A 162ALA A 172 | 6UI A 700 ( 4.9A)6UI A 700 (-3.3A)6UI A 700 (-4.3A)6UI A 700 ( 4.2A)6UI A 700 (-4.2A)6UI A 700 ( 4.1A) | 0.92A | 3mssD-4usfA:19.0 | 3mssD-4usfA:28.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3OEZ_A_STIA601_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE SRC) |
4usf | STE20-LIKESERINE/THREONINE-PROTEIN KINASE (Homosapiens) | 7 / 12 | VAL A 48ALA A 61VAL A 92GLY A 114LEU A 162ALA A 172ASP A 173 | None6UI A 700 (-3.3A)None6UI A 700 ( 4.2A)6UI A 700 (-4.2A)6UI A 700 ( 4.1A)None | 0.73A | 3oezA-4usfA:19.1 | 3oezA-4usfA:26.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3OXZ_A_0LIA1_1 (TYROSINE-PROTEINKINASE ABL1) |
4usf | STE20-LIKESERINE/THREONINE-PROTEIN KINASE (Homosapiens) | 6 / 12 | ALA A 61VAL A 92GLY A 114HIS A 153ALA A 172ASP A 173 | 6UI A 700 (-3.3A)None6UI A 700 ( 4.2A)None6UI A 700 ( 4.1A)None | 0.79A | 3oxzA-4usfA:23.6 | 3oxzA-4usfA:27.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3UE4_A_DB8A601_1 (TYROSINE-PROTEINKINASE ABL1) |
4usf | STE20-LIKESERINE/THREONINE-PROTEIN KINASE (Homosapiens) | 7 / 12 | LEU A 40ALA A 61LYS A 63VAL A 92ILE A 106PHE A 110LEU A 162 | 6UI A 700 ( 4.9A)6UI A 700 (-3.3A)6UI A 700 (-4.5A)None6UI A 700 (-3.5A)6UI A 700 (-4.3A)6UI A 700 (-4.2A) | 0.76A | 3ue4A-4usfA:17.7 | 3ue4A-4usfA:29.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3UE4_A_DB8A601_1 (TYROSINE-PROTEINKINASE ABL1) |
4usf | STE20-LIKESERINE/THREONINE-PROTEIN KINASE (Homosapiens) | 7 / 12 | LEU A 40ALA A 61VAL A 92ILE A 106PHE A 110GLY A 114LEU A 162 | 6UI A 700 ( 4.9A)6UI A 700 (-3.3A)None6UI A 700 (-3.5A)6UI A 700 (-4.3A)6UI A 700 ( 4.2A)6UI A 700 (-4.2A) | 0.58A | 3ue4A-4usfA:17.7 | 3ue4A-4usfA:29.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3UE4_B_DB8B601_1 (TYROSINE-PROTEINKINASE ABL1) |
4usf | STE20-LIKESERINE/THREONINE-PROTEIN KINASE (Homosapiens) | 8 / 12 | LEU A 40VAL A 48ALA A 61VAL A 92ILE A 106PHE A 110GLY A 114LEU A 162 | 6UI A 700 ( 4.9A)None6UI A 700 (-3.3A)None6UI A 700 (-3.5A)6UI A 700 (-4.3A)6UI A 700 ( 4.2A)6UI A 700 (-4.2A) | 0.68A | 3ue4B-4usfA:23.7 | 3ue4B-4usfA:29.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3WZE_A_BAXA1201_2 (VASCULAR ENDOTHELIALGROWTH FACTORRECEPTOR 2) |
4usf | STE20-LIKESERINE/THREONINE-PROTEIN KINASE (Homosapiens) | 4 / 8 | VAL A 92CYH A 111LEU A 162ASP A 173 | None6UI A 700 (-4.2A)6UI A 700 (-4.2A)None | 0.54A | 3wzeA-4usfA:18.0 | 3wzeA-4usfA:28.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4AGD_A_B49A2000_1 (VASCULAR ENDOTHELIALGROWTH FACTORRECEPTOR 2) |
4usf | STE20-LIKESERINE/THREONINE-PROTEIN KINASE (Homosapiens) | 6 / 11 | ALA A 61VAL A 92PHE A 110CYH A 111GLY A 114LEU A 162 | 6UI A 700 (-3.3A)None6UI A 700 (-4.3A)6UI A 700 (-4.2A)6UI A 700 ( 4.2A)6UI A 700 (-4.2A) | 0.64A | 4agdA-4usfA:21.6 | 4agdA-4usfA:25.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4AGD_A_B49A2000_1 (VASCULAR ENDOTHELIALGROWTH FACTORRECEPTOR 2) |
4usf | STE20-LIKESERINE/THREONINE-PROTEIN KINASE (Homosapiens) | 6 / 11 | LEU A 40ALA A 61LYS A 63PHE A 110GLY A 114LEU A 162 | 6UI A 700 ( 4.9A)6UI A 700 (-3.3A)6UI A 700 (-4.5A)6UI A 700 (-4.3A)6UI A 700 ( 4.2A)6UI A 700 (-4.2A) | 1.02A | 4agdA-4usfA:21.6 | 4agdA-4usfA:25.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4AGD_A_B49A2000_1 (VASCULAR ENDOTHELIALGROWTH FACTORRECEPTOR 2) |
4usf | STE20-LIKESERINE/THREONINE-PROTEIN KINASE (Homosapiens) | 6 / 11 | LEU A 40ALA A 61PHE A 110CYH A 111GLY A 114LEU A 162 | 6UI A 700 ( 4.9A)6UI A 700 (-3.3A)6UI A 700 (-4.3A)6UI A 700 (-4.2A)6UI A 700 ( 4.2A)6UI A 700 (-4.2A) | 0.70A | 4agdA-4usfA:21.6 | 4agdA-4usfA:25.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ANQ_A_VGHA9000_1 (ALK TYROSINE KINASERECEPTOR) |
4usf | STE20-LIKESERINE/THREONINE-PROTEIN KINASE (Homosapiens) | 6 / 9 | LEU A 40VAL A 48ALA A 61GLY A 114LEU A 162ALA A 172 | 6UI A 700 ( 4.9A)None6UI A 700 (-3.3A)6UI A 700 ( 4.2A)6UI A 700 (-4.2A)6UI A 700 ( 4.1A) | 0.56A | 4anqA-4usfA:23.6 | 4anqA-4usfA:28.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ANS_A_VGHA9000_1 (ALK TYROSINE KINASERECEPTOR) |
4usf | STE20-LIKESERINE/THREONINE-PROTEIN KINASE (Homosapiens) | 6 / 9 | LEU A 40VAL A 48ALA A 61GLY A 114LEU A 162ALA A 172 | 6UI A 700 ( 4.9A)None6UI A 700 (-3.3A)6UI A 700 ( 4.2A)6UI A 700 (-4.2A)6UI A 700 ( 4.1A) | 0.56A | 4ansA-4usfA:23.5 | 4ansA-4usfA:28.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4MXX_B_DB8B601_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE SRC) |
4usf | STE20-LIKESERINE/THREONINE-PROTEIN KINASE (Homosapiens) | 7 / 12 | LEU A 40VAL A 48ALA A 61LYS A 63VAL A 92GLY A 114LEU A 162 | 6UI A 700 ( 4.9A)None6UI A 700 (-3.3A)6UI A 700 (-4.5A)None6UI A 700 ( 4.2A)6UI A 700 (-4.2A) | 0.77A | 4mxxB-4usfA:17.8 | 4mxxB-4usfA:25.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4MXY_B_DB8B601_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE SRC) |
4usf | STE20-LIKESERINE/THREONINE-PROTEIN KINASE (Homosapiens) | 7 / 12 | LEU A 40VAL A 48ALA A 61VAL A 92GLY A 114LEU A 162ALA A 172 | 6UI A 700 ( 4.9A)None6UI A 700 (-3.3A)None6UI A 700 ( 4.2A)6UI A 700 (-4.2A)6UI A 700 ( 4.1A) | 0.56A | 4mxyB-4usfA:17.7 | 4mxyB-4usfA:26.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4MXZ_B_DB8B601_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE SRC) |
4usf | STE20-LIKESERINE/THREONINE-PROTEIN KINASE (Homosapiens) | 7 / 12 | LEU A 40VAL A 48ALA A 61VAL A 92GLY A 114LEU A 162ALA A 172 | 6UI A 700 ( 4.9A)None6UI A 700 (-3.3A)None6UI A 700 ( 4.2A)6UI A 700 (-4.2A)6UI A 700 ( 4.1A) | 0.56A | 4mxzB-4usfA:17.7 | 4mxzB-4usfA:26.27 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4O0U_A_ADNA501_1 (AURORA KINASE A) |
4usf | STE20-LIKESERINE/THREONINE-PROTEIN KINASE (Homosapiens) | 4 / 6 | VAL A 48ALA A 61LYS A 63LEU A 162 | None6UI A 700 (-3.3A)6UI A 700 (-4.5A)6UI A 700 (-4.2A) | 0.76A | 4o0uA-4usfA:19.6 | 4o0uA-4usfA:30.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4OTW_A_DB8A1101_1 (RECEPTORTYROSINE-PROTEINKINASE ERBB-3) |
4usf | STE20-LIKESERINE/THREONINE-PROTEIN KINASE (Homosapiens) | 7 / 12 | LEU A 40VAL A 48LYS A 63VAL A 92GLY A 114LEU A 162ALA A 172 | 6UI A 700 ( 4.9A)None6UI A 700 (-4.5A)None6UI A 700 ( 4.2A)6UI A 700 (-4.2A)6UI A 700 ( 4.1A) | 0.81A | 4otwA-4usfA:17.3 | 4otwA-4usfA:27.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4TWP_B_AXIB601_1 (TYROSINE-PROTEINKINASE ABL1) |
4usf | STE20-LIKESERINE/THREONINE-PROTEIN KINASE (Homosapiens) | 8 / 12 | LEU A 40VAL A 48ALA A 61PHE A 110GLY A 114ASN A 160LEU A 162ALA A 172 | 6UI A 700 ( 4.9A)None6UI A 700 (-3.3A)6UI A 700 (-4.3A)6UI A 700 ( 4.2A)None6UI A 700 (-4.2A)6UI A 700 ( 4.1A) | 1.02A | 4twpB-4usfA:18.3 | 4twpB-4usfA:28.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4UXQ_A_0LIA1752_1 (FIBROBLAST GROWTHFACTOR RECEPTOR 4) |
4usf | STE20-LIKESERINE/THREONINE-PROTEIN KINASE (Homosapiens) | 6 / 12 | ALA A 61LEU A 146HIS A 153LEU A 162ALA A 172ASP A 173 | 6UI A 700 (-3.3A)NoneNone6UI A 700 (-4.2A)6UI A 700 ( 4.1A)None | 0.93A | 4uxqA-4usfA:18.3 | 4uxqA-4usfA:27.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4WA9_A_AXIA9000_1 (TYROSINE-PROTEINKINASE ABL1) |
4usf | STE20-LIKESERINE/THREONINE-PROTEIN KINASE (Homosapiens) | 7 / 11 | LEU A 40ALA A 61GLY A 114ASN A 160LEU A 162ALA A 172PHE A 174 | 6UI A 700 ( 4.9A)6UI A 700 (-3.3A)6UI A 700 ( 4.2A)None6UI A 700 (-4.2A)6UI A 700 ( 4.1A)None | 1.01A | 4wa9A-4usfA:21.5 | 4wa9A-4usfA:29.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4WA9_B_AXIB9000_1 (TYROSINE-PROTEINKINASE ABL1) |
4usf | STE20-LIKESERINE/THREONINE-PROTEIN KINASE (Homosapiens) | 7 / 12 | ALA A 61PHE A 110GLY A 114ASN A 160LEU A 162ALA A 172PHE A 174 | 6UI A 700 (-3.3A)6UI A 700 (-4.3A)6UI A 700 ( 4.2A)None6UI A 700 (-4.2A)6UI A 700 ( 4.1A)None | 1.31A | 4wa9B-4usfA:18.0 | 4wa9B-4usfA:29.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4WA9_B_AXIB9000_1 (TYROSINE-PROTEINKINASE ABL1) |
4usf | STE20-LIKESERINE/THREONINE-PROTEIN KINASE (Homosapiens) | 7 / 12 | VAL A 48ALA A 61PHE A 110GLY A 114ASN A 160LEU A 162ALA A 172 | None6UI A 700 (-3.3A)6UI A 700 (-4.3A)6UI A 700 ( 4.2A)None6UI A 700 (-4.2A)6UI A 700 ( 4.1A) | 1.04A | 4wa9B-4usfA:18.0 | 4wa9B-4usfA:29.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4XEY_A_1N1A601_1 (TYROSINE-PROTEINKINASE ABL1) |
4usf | STE20-LIKESERINE/THREONINE-PROTEIN KINASE (Homosapiens) | 10 / 12 | LEU A 40VAL A 48ALA A 61LYS A 63VAL A 92ILE A 106PHE A 110GLY A 114LEU A 162ALA A 172 | 6UI A 700 ( 4.9A)None6UI A 700 (-3.3A)6UI A 700 (-4.5A)None6UI A 700 (-3.5A)6UI A 700 (-4.3A)6UI A 700 ( 4.2A)6UI A 700 (-4.2A)6UI A 700 ( 4.1A) | 0.90A | 4xeyA-4usfA:17.5 | 4xeyA-4usfA:25.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4XEY_B_1N1B601_1 (TYROSINE-PROTEINKINASE ABL1) |
4usf | STE20-LIKESERINE/THREONINE-PROTEIN KINASE (Homosapiens) | 10 / 12 | LEU A 40VAL A 48ALA A 61LYS A 63VAL A 92ILE A 106PHE A 110GLY A 114LEU A 162ALA A 172 | 6UI A 700 ( 4.9A)None6UI A 700 (-3.3A)6UI A 700 (-4.5A)None6UI A 700 (-3.5A)6UI A 700 (-4.3A)6UI A 700 ( 4.2A)6UI A 700 (-4.2A)6UI A 700 ( 4.1A) | 0.86A | 4xeyB-4usfA:16.3 | 4xeyB-4usfA:25.71 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5AJQ_A_DB8A800_1 (SERINE/THREONINE-PROTEIN KINASE 10) |
4usf | STE20-LIKESERINE/THREONINE-PROTEIN KINASE (Homosapiens) | 9 / 12 | LEU A 40GLY A 41ALA A 61LYS A 63PHE A 110CYH A 111GLY A 114LEU A 162ALA A 172 | 6UI A 700 ( 4.9A)None6UI A 700 (-3.3A)6UI A 700 (-4.5A)6UI A 700 (-4.3A)6UI A 700 (-4.2A)6UI A 700 ( 4.2A)6UI A 700 (-4.2A)6UI A 700 ( 4.1A) | 0.78A | 5ajqA-4usfA:36.2 | 5ajqA-4usfA:75.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5H2U_C_1N1C501_1 (PROTEIN-TYROSINEKINASE 6) |
4usf | STE20-LIKESERINE/THREONINE-PROTEIN KINASE (Homosapiens) | 5 / 12 | LEU A 40ALA A 61ILE A 106GLY A 114LEU A 162 | 6UI A 700 ( 4.9A)6UI A 700 (-3.3A)6UI A 700 (-3.5A)6UI A 700 ( 4.2A)6UI A 700 (-4.2A) | 0.55A | 5h2uC-4usfA:17.7 | 5h2uC-4usfA:27.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5H2U_D_1N1D504_1 (PROTEIN-TYROSINEKINASE 6) |
4usf | STE20-LIKESERINE/THREONINE-PROTEIN KINASE (Homosapiens) | 6 / 12 | LEU A 40VAL A 48ALA A 61ILE A 106GLY A 114LEU A 162 | 6UI A 700 ( 4.9A)None6UI A 700 (-3.3A)6UI A 700 (-3.5A)6UI A 700 ( 4.2A)6UI A 700 (-4.2A) | 0.57A | 5h2uD-4usfA:17.7 | 5h2uD-4usfA:27.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5MO4_A_NILA601_2 (TYROSINE-PROTEINKINASE ABL1) |
4usf | STE20-LIKESERINE/THREONINE-PROTEIN KINASE (Homosapiens) | 6 / 12 | ALA A 61VAL A 92HIS A 153LEU A 162ALA A 172ASP A 173 | 6UI A 700 (-3.3A)NoneNone6UI A 700 (-4.2A)6UI A 700 ( 4.1A)None | 0.69A | 5mo4A-4usfA:14.8 | 5mo4A-4usfA:20.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5P9I_A_1E8A701_1 (TYROSINE-PROTEINKINASE BTK) |
4usf | STE20-LIKESERINE/THREONINE-PROTEIN KINASE (Homosapiens) | 6 / 12 | VAL A 48ALA A 61LYS A 63ILE A 106GLY A 114LEU A 162 | None6UI A 700 (-3.3A)6UI A 700 (-4.5A)6UI A 700 (-3.5A)6UI A 700 ( 4.2A)6UI A 700 (-4.2A) | 0.81A | 5p9iA-4usfA:18.2 | 5p9iA-4usfA:26.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6HD6_A_STIA603_0 (TYROSINE-PROTEINKINASE ABL1) |
4usf | STE20-LIKESERINE/THREONINE-PROTEIN KINASE (Homosapiens) | 7 / 12 | VAL A 48ALA A 61VAL A 92ILE A 106PHE A 110LEU A 162ALA A 172 | None6UI A 700 (-3.3A)None6UI A 700 (-3.5A)6UI A 700 (-4.3A)6UI A 700 (-4.2A)6UI A 700 ( 4.1A) | 0.95A | 6hd6A-4usfA:23.9 | 6hd6A-4usfA:12.45 |