SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6P6'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1IEP_A_STIA201_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL)		 5l6o EPHRIN TYPE-B
RECEPTOR 3
(Homo
sapiens) 		7 / 12 VAL A 647
ALA A 663
MET A 686
THR A 711
PHE A 713
LEU A 765
ASP A 776
 None
6P6  A1001 (-3.3A)
6P6  A1001 ( 4.2A)
6P6  A1001 (-3.5A)
6P6  A1001 ( 4.5A)
6P6  A1001 (-4.5A)
None
 0.77A 1iepA-5l6oA:
33.3		 1iepA-5l6oA:
37.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1IEP_A_STIA201_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL)		 5l6o EPHRIN TYPE-B
RECEPTOR 3
(Homo
sapiens) 		4 / 6 LYS A 665
ILE A 709
MET A 714
ARG A 757
 None
6P6  A1001 ( 4.5A)
None
None
 0.73A 1iepA-5l6oA:
33.3		 1iepA-5l6oA:
37.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1IEP_B_STIB202_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL)		 5l6o EPHRIN TYPE-B
RECEPTOR 3
(Homo
sapiens) 		6 / 12 VAL A 647
ALA A 663
MET A 686
THR A 711
PHE A 713
ASP A 776
 None
6P6  A1001 (-3.3A)
6P6  A1001 ( 4.2A)
6P6  A1001 (-3.5A)
6P6  A1001 ( 4.5A)
None
 0.61A 1iepB-5l6oA:
33.0		 1iepB-5l6oA:
37.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1OPJ_A_STIA3_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 5l6o EPHRIN TYPE-B
RECEPTOR 3
(Homo
sapiens) 		6 / 12 VAL A 647
ALA A 663
THR A 711
PHE A 713
LEU A 765
ASP A 776
 None
6P6  A1001 (-3.3A)
6P6  A1001 (-3.5A)
6P6  A1001 ( 4.5A)
6P6  A1001 (-4.5A)
None
 0.65A 1opjA-5l6oA:
32.8		 1opjA-5l6oA:
37.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1OPJ_B_STIB4_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 5l6o EPHRIN TYPE-B
RECEPTOR 3
(Homo
sapiens) 		6 / 12 VAL A 647
ALA A 663
MET A 686
THR A 711
PHE A 713
ASP A 776
 None
6P6  A1001 (-3.3A)
6P6  A1001 ( 4.2A)
6P6  A1001 (-3.5A)
6P6  A1001 ( 4.5A)
None
 0.77A 1opjB-5l6oA:
33.3		 1opjB-5l6oA:
37.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1OPJ_B_STIB4_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 5l6o EPHRIN TYPE-B
RECEPTOR 3
(Homo
sapiens) 		4 / 6 LYS A 665
ILE A 709
MET A 714
ARG A 757
 None
6P6  A1001 ( 4.5A)
None
None
 0.75A 1opjB-5l6oA:
33.3		 1opjB-5l6oA:
37.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1UWJ_A_BAXA1723_1
(B-RAF PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE)		 5l6o EPHRIN TYPE-B
RECEPTOR 3
(Homo
sapiens) 		5 / 12 VAL A 647
ALA A 663
THR A 711
LEU A 749
HIS A 756
 None
6P6  A1001 (-3.3A)
6P6  A1001 (-3.5A)
None
DIO  A1002 (-4.1A)
 0.51A 1uwjA-5l6oA:
27.6		 1uwjA-5l6oA:
33.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1UWJ_B_BAXB1723_1
(B-RAF PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE)		 5l6o EPHRIN TYPE-B
RECEPTOR 3
(Homo
sapiens) 		6 / 12 ILE A 639
VAL A 647
ALA A 663
THR A 711
LEU A 749
HIS A 756
 6P6  A1001 (-4.0A)
None
6P6  A1001 (-3.3A)
6P6  A1001 (-3.5A)
None
DIO  A1002 (-4.1A)
 0.62A 1uwjB-5l6oA:
8.3		 1uwjB-5l6oA:
33.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2GQG_A_1N1A501_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 5l6o EPHRIN TYPE-B
RECEPTOR 3
(Homo
sapiens) 		7 / 12 ALA A 663
LYS A 665
MET A 686
ILE A 709
THR A 711
PHE A 713
LEU A 765
 6P6  A1001 (-3.3A)
None
6P6  A1001 ( 4.2A)
6P6  A1001 ( 4.5A)
6P6  A1001 (-3.5A)
6P6  A1001 ( 4.5A)
6P6  A1001 (-4.5A)
 0.67A 2gqgA-5l6oA:
31.8		 2gqgA-5l6oA:
38.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HYY_A_STIA600_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 5l6o EPHRIN TYPE-B
RECEPTOR 3
(Homo
sapiens) 		7 / 12 VAL A 647
ALA A 663
MET A 686
THR A 711
PHE A 713
LEU A 765
ASP A 776
 None
6P6  A1001 (-3.3A)
6P6  A1001 ( 4.2A)
6P6  A1001 (-3.5A)
6P6  A1001 ( 4.5A)
6P6  A1001 (-4.5A)
None
 0.87A 2hyyA-5l6oA:
33.5		 2hyyA-5l6oA:
38.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HYY_B_STIB600_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 5l6o EPHRIN TYPE-B
RECEPTOR 3
(Homo
sapiens) 		7 / 12 VAL A 647
ALA A 663
MET A 686
THR A 711
PHE A 713
LEU A 765
ASP A 776
 None
6P6  A1001 (-3.3A)
6P6  A1001 ( 4.2A)
6P6  A1001 (-3.5A)
6P6  A1001 ( 4.5A)
6P6  A1001 (-4.5A)
None
 0.78A 2hyyB-5l6oA:
33.6		 2hyyB-5l6oA:
38.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HYY_C_STIC600_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 5l6o EPHRIN TYPE-B
RECEPTOR 3
(Homo
sapiens) 		4 / 6 LYS A 665
MET A 686
ILE A 709
MET A 714
 None
6P6  A1001 ( 4.2A)
6P6  A1001 ( 4.5A)
None
 0.69A 2hyyC-5l6oA:
33.3		 2hyyC-5l6oA:
38.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HYY_D_STID600_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 5l6o EPHRIN TYPE-B
RECEPTOR 3
(Homo
sapiens) 		6 / 12 VAL A 647
ALA A 663
ILE A 685
THR A 711
PHE A 713
LEU A 765
 None
6P6  A1001 (-3.3A)
None
6P6  A1001 (-3.5A)
6P6  A1001 ( 4.5A)
6P6  A1001 (-4.5A)
 1.26A 2hyyD-5l6oA:
33.5		 2hyyD-5l6oA:
38.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HYY_D_STID600_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 5l6o EPHRIN TYPE-B
RECEPTOR 3
(Homo
sapiens) 		7 / 12 VAL A 647
ALA A 663
ILE A 709
THR A 711
PHE A 713
LEU A 765
ASP A 776
 None
6P6  A1001 (-3.3A)
6P6  A1001 ( 4.5A)
6P6  A1001 (-3.5A)
6P6  A1001 ( 4.5A)
6P6  A1001 (-4.5A)
None
 0.73A 2hyyD-5l6oA:
33.5		 2hyyD-5l6oA:
38.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HYY_D_STID600_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 5l6o EPHRIN TYPE-B
RECEPTOR 3
(Homo
sapiens) 		7 / 12 VAL A 647
ALA A 663
MET A 686
ILE A 709
THR A 711
PHE A 713
ASP A 776
 None
6P6  A1001 (-3.3A)
6P6  A1001 ( 4.2A)
6P6  A1001 ( 4.5A)
6P6  A1001 (-3.5A)
6P6  A1001 ( 4.5A)
None
 0.73A 2hyyD-5l6oA:
33.5		 2hyyD-5l6oA:
38.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OIQ_A_STIA1001_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 5l6o EPHRIN TYPE-B
RECEPTOR 3
(Homo
sapiens) 		8 / 12 VAL A 647
ALA A 663
LYS A 665
MET A 686
ILE A 709
THR A 711
LEU A 765
ASP A 776
 None
6P6  A1001 (-3.3A)
None
6P6  A1001 ( 4.2A)
6P6  A1001 ( 4.5A)
6P6  A1001 (-3.5A)
6P6  A1001 (-4.5A)
None
 0.65A 2oiqA-5l6oA:
32.7		 2oiqA-5l6oA:
41.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2PL0_A_STIA200_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE LCK)		 5l6o EPHRIN TYPE-B
RECEPTOR 3
(Homo
sapiens) 		7 / 12 ALA A 663
LYS A 665
MET A 686
ILE A 709
THR A 711
LEU A 765
ASP A 776
 6P6  A1001 (-3.3A)
None
6P6  A1001 ( 4.2A)
6P6  A1001 ( 4.5A)
6P6  A1001 (-3.5A)
6P6  A1001 (-4.5A)
None
 0.80A 2pl0A-5l6oA:
31.0		 2pl0A-5l6oA:
40.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2PL0_A_STIA200_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE LCK)		 5l6o EPHRIN TYPE-B
RECEPTOR 3
(Homo
sapiens) 		7 / 12 VAL A 647
ALA A 663
LYS A 665
MET A 686
ILE A 709
THR A 711
ASP A 776
 None
6P6  A1001 (-3.3A)
None
6P6  A1001 ( 4.2A)
6P6  A1001 ( 4.5A)
6P6  A1001 (-3.5A)
None
 0.69A 2pl0A-5l6oA:
31.0		 2pl0A-5l6oA:
40.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y6O_A_1N1A1892_1
(EPHRIN TYPE-A
RECEPTOR 4)		 5l6o EPHRIN TYPE-B
RECEPTOR 3
(Homo
sapiens) 		8 / 12 ILE A 639
ALA A 663
LYS A 665
MET A 686
ILE A 709
THR A 711
LEU A 765
SER A 775
 6P6  A1001 (-4.0A)
6P6  A1001 (-3.3A)
None
6P6  A1001 ( 4.2A)
6P6  A1001 ( 4.5A)
6P6  A1001 (-3.5A)
6P6  A1001 (-4.5A)
6P6  A1001 ( 3.7A)
 0.63A 2y6oA-5l6oA:
37.5		 2y6oA-5l6oA:
81.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CS9_A_NILA600_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 5l6o EPHRIN TYPE-B
RECEPTOR 3
(Homo
sapiens) 		6 / 10 VAL A 647
LYS A 665
ILE A 709
PHE A 713
VAL A 774
ASP A 776
 None
None
6P6  A1001 ( 4.5A)
6P6  A1001 ( 4.5A)
DIO  A1002 (-4.9A)
None
 0.57A 3cs9A-5l6oA:
33.5		 3cs9A-5l6oA:
37.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CS9_B_NILB600_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 5l6o EPHRIN TYPE-B
RECEPTOR 3
(Homo
sapiens) 		5 / 12 ALA A 663
MET A 686
THR A 711
HIS A 756
ASP A 776
 6P6  A1001 (-3.3A)
6P6  A1001 ( 4.2A)
6P6  A1001 (-3.5A)
DIO  A1002 (-4.1A)
None
 0.55A 3cs9B-5l6oA:
31.8		 3cs9B-5l6oA:
37.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CS9_B_NILB600_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 5l6o EPHRIN TYPE-B
RECEPTOR 3
(Homo
sapiens) 		5 / 9 VAL A 647
LYS A 665
ILE A 709
LEU A 765
VAL A 774
 None
None
6P6  A1001 ( 4.5A)
6P6  A1001 (-4.5A)
DIO  A1002 (-4.9A)
 0.74A 3cs9B-5l6oA:
31.8		 3cs9B-5l6oA:
37.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CS9_C_NILC600_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 5l6o EPHRIN TYPE-B
RECEPTOR 3
(Homo
sapiens) 		6 / 12 ALA A 663
MET A 686
THR A 711
PHE A 713
HIS A 756
ASP A 776
 6P6  A1001 (-3.3A)
6P6  A1001 ( 4.2A)
6P6  A1001 (-3.5A)
6P6  A1001 ( 4.5A)
DIO  A1002 (-4.1A)
None
 0.62A 3cs9C-5l6oA:
31.2		 3cs9C-5l6oA:
37.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CS9_C_NILC600_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 5l6o EPHRIN TYPE-B
RECEPTOR 3
(Homo
sapiens) 		5 / 9 VAL A 647
LYS A 665
ILE A 709
MET A 714
VAL A 774
 None
None
6P6  A1001 ( 4.5A)
None
DIO  A1002 (-4.9A)
 0.62A 3cs9C-5l6oA:
31.2		 3cs9C-5l6oA:
37.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CS9_D_NILD600_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 5l6o EPHRIN TYPE-B
RECEPTOR 3
(Homo
sapiens) 		5 / 12 ALA A 663
MET A 686
THR A 711
PHE A 713
HIS A 756
 6P6  A1001 (-3.3A)
6P6  A1001 ( 4.2A)
6P6  A1001 (-3.5A)
6P6  A1001 ( 4.5A)
DIO  A1002 (-4.1A)
 0.59A 3cs9D-5l6oA:
32.7		 3cs9D-5l6oA:
37.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CS9_D_NILD600_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 5l6o EPHRIN TYPE-B
RECEPTOR 3
(Homo
sapiens) 		4 / 6 VAL A 647
LYS A 665
LEU A 765
ASP A 776
 None
None
6P6  A1001 (-4.5A)
None
 0.85A 3cs9D-5l6oA:
32.7		 3cs9D-5l6oA:
37.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GCS_A_BAXA401_1
(MITOGEN-ACTIVATED
PROTEIN KINASE 14)		 5l6o EPHRIN TYPE-B
RECEPTOR 3
(Homo
sapiens) 		6 / 12 VAL A 647
ALA A 663
ILE A 695
THR A 711
HIS A 756
ASP A 776
 None
6P6  A1001 (-3.3A)
None
6P6  A1001 (-3.5A)
DIO  A1002 (-4.1A)
None
 1.03A 3gcsA-5l6oA:
20.5		 3gcsA-5l6oA:
25.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GP0_A_NILA1_1
(MITOGEN-ACTIVATED
PROTEIN KINASE 11)		 5l6o EPHRIN TYPE-B
RECEPTOR 3
(Homo
sapiens) 		6 / 12 VAL A 647
ALA A 663
ILE A 695
THR A 711
HIS A 756
ASP A 776
 None
6P6  A1001 (-3.3A)
None
6P6  A1001 (-3.5A)
DIO  A1002 (-4.1A)
None
 0.62A 3gp0A-5l6oA:
22.1		 3gp0A-5l6oA:
25.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GVU_A_STIA1001_1
(TYROSINE-PROTEIN
KINASE ABL2)		 5l6o EPHRIN TYPE-B
RECEPTOR 3
(Homo
sapiens) 		6 / 12 VAL A 647
ALA A 663
MET A 686
THR A 711
LEU A 765
ASP A 776
 None
6P6  A1001 (-3.3A)
6P6  A1001 ( 4.2A)
6P6  A1001 (-3.5A)
6P6  A1001 (-4.5A)
None
 0.75A 3gvuA-5l6oA:
33.3		 3gvuA-5l6oA:
36.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HEG_A_BAXA1_1
(MITOGEN-ACTIVATED
PROTEIN KINASE 14)		 5l6o EPHRIN TYPE-B
RECEPTOR 3
(Homo
sapiens) 		5 / 12 VAL A 647
ALA A 663
LYS A 665
THR A 711
ASP A 776
 None
6P6  A1001 (-3.3A)
None
6P6  A1001 (-3.5A)
None
 0.72A 3hegA-5l6oA:
21.1		 3hegA-5l6oA:
25.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K5V_A_STIA2_1
(TYROSINE-PROTEIN
KINASE ABL1)		 5l6o EPHRIN TYPE-B
RECEPTOR 3
(Homo
sapiens) 		6 / 12 VAL A 647
ALA A 663
MET A 686
THR A 711
PHE A 713
ASP A 776
 None
6P6  A1001 (-3.3A)
6P6  A1001 ( 4.2A)
6P6  A1001 (-3.5A)
6P6  A1001 ( 4.5A)
None
 0.67A 3k5vA-5l6oA:
33.3		 3k5vA-5l6oA:
37.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K5V_A_STIA2_1
(TYROSINE-PROTEIN
KINASE ABL1)		 5l6o EPHRIN TYPE-B
RECEPTOR 3
(Homo
sapiens) 		6 / 12 VAL A 647
ALA A 663
THR A 711
PHE A 713
LEU A 765
ASP A 776
 None
6P6  A1001 (-3.3A)
6P6  A1001 (-3.5A)
6P6  A1001 ( 4.5A)
6P6  A1001 (-4.5A)
None
 0.67A 3k5vA-5l6oA:
33.3		 3k5vA-5l6oA:
37.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K5V_B_STIB2_1
(TYROSINE-PROTEIN
KINASE ABL1)		 5l6o EPHRIN TYPE-B
RECEPTOR 3
(Homo
sapiens) 		7 / 12 VAL A 647
ALA A 663
MET A 686
THR A 711
PHE A 713
LEU A 765
ASP A 776
 None
6P6  A1001 (-3.3A)
6P6  A1001 ( 4.2A)
6P6  A1001 (-3.5A)
6P6  A1001 ( 4.5A)
6P6  A1001 (-4.5A)
None
 0.78A 3k5vB-5l6oA:
33.1		 3k5vB-5l6oA:
37.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MIY_A_B49A1_1
(TYROSINE-PROTEIN
KINASE ITK/TSK)		 5l6o EPHRIN TYPE-B
RECEPTOR 3
(Homo
sapiens) 		6 / 11 ILE A 639
ALA A 663
PHE A 713
MET A 714
LEU A 765
SER A 775
 6P6  A1001 (-4.0A)
6P6  A1001 (-3.3A)
6P6  A1001 ( 4.5A)
None
6P6  A1001 (-4.5A)
6P6  A1001 ( 3.7A)
 0.45A 3miyA-5l6oA:
32.6		 3miyA-5l6oA:
38.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MIY_B_B49B2_1
(TYROSINE-PROTEIN
KINASE ITK/TSK)		 5l6o EPHRIN TYPE-B
RECEPTOR 3
(Homo
sapiens) 		6 / 9 ILE A 639
ALA A 663
PHE A 713
MET A 714
LEU A 765
SER A 775
 6P6  A1001 (-4.0A)
6P6  A1001 (-3.3A)
6P6  A1001 ( 4.5A)
None
6P6  A1001 (-4.5A)
6P6  A1001 ( 3.7A)
 0.38A 3miyB-5l6oA:
32.5		 3miyB-5l6oA:
38.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MS9_A_STIA1_1
(TYROSINE-PROTEIN
KINASE ABL1)		 5l6o EPHRIN TYPE-B
RECEPTOR 3
(Homo
sapiens) 		7 / 12 VAL A 647
ALA A 663
MET A 686
THR A 711
PHE A 713
LEU A 765
ASP A 776
 None
6P6  A1001 (-3.3A)
6P6  A1001 ( 4.2A)
6P6  A1001 (-3.5A)
6P6  A1001 ( 4.5A)
6P6  A1001 (-4.5A)
None
 0.78A 3ms9A-5l6oA:
32.7		 3ms9A-5l6oA:
37.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MSS_A_STIA1_1
(TYROSINE-PROTEIN
KINASE ABL1)		 5l6o EPHRIN TYPE-B
RECEPTOR 3
(Homo
sapiens) 		7 / 12 VAL A 647
ALA A 663
MET A 686
THR A 711
PHE A 713
LEU A 765
ASP A 776
 None
6P6  A1001 (-3.3A)
6P6  A1001 ( 4.2A)
6P6  A1001 (-3.5A)
6P6  A1001 ( 4.5A)
6P6  A1001 (-4.5A)
None
 0.79A 3mssA-5l6oA:
33.0		 3mssA-5l6oA:
37.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MSS_A_STIA1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 5l6o EPHRIN TYPE-B
RECEPTOR 3
(Homo
sapiens) 		4 / 6 LYS A 665
ILE A 709
MET A 714
ARG A 757
 None
6P6  A1001 ( 4.5A)
None
None
 1.13A 3mssA-5l6oA:
33.0		 3mssA-5l6oA:
37.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MSS_B_STIB1_1
(TYROSINE-PROTEIN
KINASE ABL1)		 5l6o EPHRIN TYPE-B
RECEPTOR 3
(Homo
sapiens) 		6 / 12 VAL A 647
ALA A 663
MET A 686
THR A 711
PHE A 713
ASP A 776
 None
6P6  A1001 (-3.3A)
6P6  A1001 ( 4.2A)
6P6  A1001 (-3.5A)
6P6  A1001 ( 4.5A)
None
 0.68A 3mssB-5l6oA:
33.1		 3mssB-5l6oA:
37.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MSS_B_STIB1_1
(TYROSINE-PROTEIN
KINASE ABL1)		 5l6o EPHRIN TYPE-B
RECEPTOR 3
(Homo
sapiens) 		6 / 12 VAL A 647
ALA A 663
THR A 711
PHE A 713
LEU A 765
ASP A 776
 None
6P6  A1001 (-3.3A)
6P6  A1001 (-3.5A)
6P6  A1001 ( 4.5A)
6P6  A1001 (-4.5A)
None
 0.69A 3mssB-5l6oA:
33.1		 3mssB-5l6oA:
37.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MSS_B_STIB1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 5l6o EPHRIN TYPE-B
RECEPTOR 3
(Homo
sapiens) 		4 / 7 LYS A 665
ILE A 709
MET A 714
ARG A 757
 None
6P6  A1001 ( 4.5A)
None
None
 0.70A 3mssB-5l6oA:
33.1		 3mssB-5l6oA:
37.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MSS_C_STIC1_1
(TYROSINE-PROTEIN
KINASE ABL1)		 5l6o EPHRIN TYPE-B
RECEPTOR 3
(Homo
sapiens) 		6 / 12 VAL A 647
ALA A 663
MET A 686
THR A 711
PHE A 713
ASP A 776
 None
6P6  A1001 (-3.3A)
6P6  A1001 ( 4.2A)
6P6  A1001 (-3.5A)
6P6  A1001 ( 4.5A)
None
 0.66A 3mssC-5l6oA:
32.9		 3mssC-5l6oA:
37.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MSS_C_STIC1_1
(TYROSINE-PROTEIN
KINASE ABL1)		 5l6o EPHRIN TYPE-B
RECEPTOR 3
(Homo
sapiens) 		6 / 12 VAL A 647
ALA A 663
THR A 711
PHE A 713
LEU A 765
ASP A 776
 None
6P6  A1001 (-3.3A)
6P6  A1001 (-3.5A)
6P6  A1001 ( 4.5A)
6P6  A1001 (-4.5A)
None
 0.67A 3mssC-5l6oA:
32.9		 3mssC-5l6oA:
37.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MSS_D_STID1_1
(TYROSINE-PROTEIN
KINASE ABL1)		 5l6o EPHRIN TYPE-B
RECEPTOR 3
(Homo
sapiens) 		6 / 12 ALA A 663
MET A 686
THR A 711
PHE A 713
LEU A 765
ASP A 776
 6P6  A1001 (-3.3A)
6P6  A1001 ( 4.2A)
6P6  A1001 (-3.5A)
6P6  A1001 ( 4.5A)
6P6  A1001 (-4.5A)
None
 0.72A 3mssD-5l6oA:
33.0		 3mssD-5l6oA:
37.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MSS_D_STID1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 5l6o EPHRIN TYPE-B
RECEPTOR 3
(Homo
sapiens) 		4 / 6 VAL A 647
LYS A 665
ILE A 709
MET A 714
 None
None
6P6  A1001 ( 4.5A)
None
 0.69A 3mssD-5l6oA:
33.0		 3mssD-5l6oA:
37.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OEZ_A_STIA601_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 5l6o EPHRIN TYPE-B
RECEPTOR 3
(Homo
sapiens) 		4 / 5 LYS A 665
ILE A 709
MET A 714
ARG A 757
 None
6P6  A1001 ( 4.5A)
None
None
 1.00A 3oezA-5l6oA:
32.3		 3oezA-5l6oA:
41.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OEZ_B_STIB601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 5l6o EPHRIN TYPE-B
RECEPTOR 3
(Homo
sapiens) 		8 / 12 VAL A 647
ALA A 663
LYS A 665
MET A 686
ILE A 709
THR A 711
LEU A 765
ASP A 776
 None
6P6  A1001 (-3.3A)
None
6P6  A1001 ( 4.2A)
6P6  A1001 ( 4.5A)
6P6  A1001 (-3.5A)
6P6  A1001 (-4.5A)
None
 0.75A 3oezB-5l6oA:
32.2		 3oezB-5l6oA:
41.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OG7_A_032A1_1
(AKAP9-BRAF FUSION
PROTEIN)		 5l6o EPHRIN TYPE-B
RECEPTOR 3
(Homo
sapiens) 		5 / 12 ILE A 639
VAL A 647
ALA A 663
LYS A 665
THR A 711
 6P6  A1001 (-4.0A)
None
6P6  A1001 (-3.3A)
None
6P6  A1001 (-3.5A)
 0.74A 3og7A-5l6oA:
26.8		 3og7A-5l6oA:
30.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OHT_A_1N1A1000_1
(P38A)		 5l6o EPHRIN TYPE-B
RECEPTOR 3
(Homo
sapiens) 		7 / 12 GLY A 640
VAL A 647
ALA A 663
LYS A 665
ILE A 695
THR A 711
LEU A 765
 None
None
6P6  A1001 (-3.3A)
None
None
6P6  A1001 (-3.5A)
6P6  A1001 (-4.5A)
 1.14A 3ohtA-5l6oA:
5.9		 3ohtA-5l6oA:
24.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OXZ_A_0LIA1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 5l6o EPHRIN TYPE-B
RECEPTOR 3
(Homo
sapiens) 		6 / 9 LYS A 665
ILE A 709
MET A 714
ARG A 757
LEU A 765
VAL A 774
 None
6P6  A1001 ( 4.5A)
None
None
6P6  A1001 (-4.5A)
DIO  A1002 (-4.9A)
 0.98A 3oxzA-5l6oA:
31.6		 3oxzA-5l6oA:
37.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3PYY_A_STIA3_1
(V-ABL ABELSON MURINE
LEUKEMIA VIRAL
ONCOGENE HOMOLOG 1
ISOFORM B VARIANT)		 5l6o EPHRIN TYPE-B
RECEPTOR 3
(Homo
sapiens) 		6 / 12 VAL A 647
ALA A 663
THR A 711
PHE A 713
LEU A 765
ASP A 776
 None
6P6  A1001 (-3.3A)
6P6  A1001 (-3.5A)
6P6  A1001 ( 4.5A)
6P6  A1001 (-4.5A)
None
 0.78A 3pyyA-5l6oA:
33.6		 3pyyA-5l6oA:
38.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3PYY_B_STIB4_1
(V-ABL ABELSON MURINE
LEUKEMIA VIRAL
ONCOGENE HOMOLOG 1
ISOFORM B VARIANT)		 5l6o EPHRIN TYPE-B
RECEPTOR 3
(Homo
sapiens) 		6 / 12 VAL A 647
ALA A 663
MET A 686
THR A 711
LEU A 765
ASP A 776
 None
6P6  A1001 (-3.3A)
6P6  A1001 ( 4.2A)
6P6  A1001 (-3.5A)
6P6  A1001 (-4.5A)
None
 0.76A 3pyyB-5l6oA:
31.1		 3pyyB-5l6oA:
38.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UE4_A_DB8A601_1
(TYROSINE-PROTEIN
KINASE ABL1)		 5l6o EPHRIN TYPE-B
RECEPTOR 3
(Homo
sapiens) 		7 / 12 ALA A 663
LYS A 665
ILE A 709
THR A 711
PHE A 713
MET A 714
LEU A 765
 6P6  A1001 (-3.3A)
None
6P6  A1001 ( 4.5A)
6P6  A1001 (-3.5A)
6P6  A1001 ( 4.5A)
None
6P6  A1001 (-4.5A)
 0.61A 3ue4A-5l6oA:
32.3		 3ue4A-5l6oA:
38.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UE4_B_DB8B601_1
(TYROSINE-PROTEIN
KINASE ABL1)		 5l6o EPHRIN TYPE-B
RECEPTOR 3
(Homo
sapiens) 		7 / 12 VAL A 647
ALA A 663
MET A 686
ILE A 709
THR A 711
PHE A 713
LEU A 765
 None
6P6  A1001 (-3.3A)
6P6  A1001 ( 4.2A)
6P6  A1001 ( 4.5A)
6P6  A1001 (-3.5A)
6P6  A1001 ( 4.5A)
6P6  A1001 (-4.5A)
 0.49A 3ue4B-5l6oA:
32.6		 3ue4B-5l6oA:
38.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ZOS_B_0LIB1000_1
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 5l6o EPHRIN TYPE-B
RECEPTOR 3
(Homo
sapiens) 		7 / 12 ALA A 663
ILE A 695
THR A 711
LEU A 749
HIS A 756
LEU A 765
ASP A 776
 6P6  A1001 (-3.3A)
None
6P6  A1001 (-3.5A)
None
DIO  A1002 (-4.1A)
6P6  A1001 (-4.5A)
None
 0.42A 3zosB-5l6oA:
31.9		 3zosB-5l6oA:
37.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ZOS_B_0LIB1000_1
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 5l6o EPHRIN TYPE-B
RECEPTOR 3
(Homo
sapiens) 		7 / 12 ILE A 695
THR A 711
LEU A 749
HIS A 756
ARG A 757
LEU A 765
ASP A 776
 None
6P6  A1001 (-3.5A)
None
DIO  A1002 (-4.1A)
None
6P6  A1001 (-4.5A)
None
 0.73A 3zosB-5l6oA:
31.9		 3zosB-5l6oA:
37.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4BKJ_A_STIA1000_1
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 5l6o EPHRIN TYPE-B
RECEPTOR 3
(Homo
sapiens) 		8 / 12 VAL A 647
ALA A 663
ILE A 685
MET A 686
ILE A 695
THR A 711
LEU A 765
ASP A 776
 None
6P6  A1001 (-3.3A)
None
6P6  A1001 ( 4.2A)
None
6P6  A1001 (-3.5A)
6P6  A1001 (-4.5A)
None
 1.02A 4bkjA-5l6oA:
31.7		 4bkjA-5l6oA:
37.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4BKJ_B_STIB1000_1
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 5l6o EPHRIN TYPE-B
RECEPTOR 3
(Homo
sapiens) 		8 / 12 VAL A 647
ALA A 663
ILE A 685
MET A 686
ILE A 695
THR A 711
LEU A 765
ASP A 776
 None
6P6  A1001 (-3.3A)
None
6P6  A1001 ( 4.2A)
None
6P6  A1001 (-3.5A)
6P6  A1001 (-4.5A)
None
 0.92A 4bkjB-5l6oA:
31.7		 4bkjB-5l6oA:
37.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RZ7_A_1E8A901_1
(CGMP-DEPENDENT
PROTEIN KINASE,
PUTATIVE)		 5l6o EPHRIN TYPE-B
RECEPTOR 3
(Homo
sapiens) 		5 / 10 ILE A 639
ALA A 663
LYS A 665
ILE A 695
THR A 711
 6P6  A1001 (-4.0A)
6P6  A1001 (-3.3A)
None
None
6P6  A1001 (-3.5A)
 0.62A 4rz7A-5l6oA:
8.3		 4rz7A-5l6oA:
13.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4TYJ_A_0LIA801_1
(FIBROBLAST GROWTH
FACTOR RECEPTOR 4)		 5l6o EPHRIN TYPE-B
RECEPTOR 3
(Homo
sapiens) 		5 / 12 ALA A 663
MET A 686
HIS A 756
LEU A 765
ASP A 776
 6P6  A1001 (-3.3A)
6P6  A1001 ( 4.2A)
DIO  A1002 (-4.1A)
6P6  A1001 (-4.5A)
None
 0.63A 4tyjA-5l6oA:
32.0		 4tyjA-5l6oA:
34.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UXQ_A_0LIA1752_1
(FIBROBLAST GROWTH
FACTOR RECEPTOR 4)		 5l6o EPHRIN TYPE-B
RECEPTOR 3
(Homo
sapiens) 		5 / 12 ALA A 663
LEU A 749
HIS A 756
LEU A 765
ASP A 776
 6P6  A1001 (-3.3A)
None
DIO  A1002 (-4.1A)
6P6  A1001 (-4.5A)
None
 0.30A 4uxqA-5l6oA:
32.2		 4uxqA-5l6oA:
34.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UXQ_A_0LIA1752_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 4)		 5l6o EPHRIN TYPE-B
RECEPTOR 3
(Homo
sapiens) 		4 / 7 LYS A 665
MET A 686
ILE A 695
ARG A 757
 None
6P6  A1001 ( 4.2A)
None
None
 0.87A 4uxqA-5l6oA:
32.2		 4uxqA-5l6oA:
34.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4V01_A_0LIA1776_1
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(FMS-RELATED
TYROSINE KINASE 2,
PFEIFFER SYNDROME),
ISOFORM CRA_B)		 5l6o EPHRIN TYPE-B
RECEPTOR 3
(Homo
sapiens) 		5 / 12 ALA A 663
MET A 686
LEU A 749
HIS A 756
ASP A 776
 6P6  A1001 (-3.3A)
6P6  A1001 ( 4.2A)
None
DIO  A1002 (-4.1A)
None
 0.78A 4v01A-5l6oA:
32.0		 4v01A-5l6oA:
31.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4V04_A_0LIA1772_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(FMS-RELATED
TYROSINE KINASE 2,
PFEIFFER SYNDROME),
ISOFORM CRA_B)		 5l6o EPHRIN TYPE-B
RECEPTOR 3
(Homo
sapiens) 		4 / 8 LYS A 665
ILE A 695
ARG A 757
LEU A 765
 None
None
None
6P6  A1001 (-4.5A)
 0.81A 4v04A-5l6oA:
31.5		 4v04A-5l6oA:
31.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4WA9_A_AXIA9000_1
(TYROSINE-PROTEIN
KINASE ABL1)		 5l6o EPHRIN TYPE-B
RECEPTOR 3
(Homo
sapiens) 		7 / 11 ALA A 663
LYS A 665
THR A 711
MET A 714
ASN A 763
LEU A 765
PHE A 777
 6P6  A1001 (-3.3A)
None
6P6  A1001 (-3.5A)
None
None
6P6  A1001 (-4.5A)
DIO  A1002 (-4.5A)
 1.29A 4wa9A-5l6oA:
28.7		 4wa9A-5l6oA:
38.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4WA9_B_AXIB9000_1
(TYROSINE-PROTEIN
KINASE ABL1)		 5l6o EPHRIN TYPE-B
RECEPTOR 3
(Homo
sapiens) 		7 / 12 ALA A 663
THR A 711
PHE A 713
MET A 714
ASN A 763
LEU A 765
PHE A 777
 6P6  A1001 (-3.3A)
6P6  A1001 (-3.5A)
6P6  A1001 ( 4.5A)
None
None
6P6  A1001 (-4.5A)
DIO  A1002 (-4.5A)
 1.30A 4wa9B-5l6oA:
31.4		 4wa9B-5l6oA:
38.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4WA9_B_AXIB9000_1
(TYROSINE-PROTEIN
KINASE ABL1)		 5l6o EPHRIN TYPE-B
RECEPTOR 3
(Homo
sapiens) 		7 / 12 VAL A 647
ALA A 663
LYS A 665
PHE A 713
MET A 714
ASN A 763
LEU A 765
 None
6P6  A1001 (-3.3A)
None
6P6  A1001 ( 4.5A)
None
None
6P6  A1001 (-4.5A)
 0.78A 4wa9B-5l6oA:
31.4		 4wa9B-5l6oA:
38.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4WA9_B_AXIB9000_1
(TYROSINE-PROTEIN
KINASE ABL1)		 5l6o EPHRIN TYPE-B
RECEPTOR 3
(Homo
sapiens) 		7 / 12 VAL A 647
ALA A 663
THR A 711
PHE A 713
MET A 714
ASN A 763
LEU A 765
 None
6P6  A1001 (-3.3A)
6P6  A1001 (-3.5A)
6P6  A1001 ( 4.5A)
None
None
6P6  A1001 (-4.5A)
 0.62A 4wa9B-5l6oA:
31.4		 4wa9B-5l6oA:
38.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HES_A_032A401_1
(MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE KINASE MLT)		 5l6o EPHRIN TYPE-B
RECEPTOR 3
(Homo
sapiens) 		5 / 12 VAL A 647
ALA A 663
ILE A 695
ILE A 709
THR A 711
 None
6P6  A1001 (-3.3A)
None
6P6  A1001 ( 4.5A)
6P6  A1001 (-3.5A)
 0.48A 5hesA-5l6oA:
11.9		 5hesA-5l6oA:
30.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5I9X_A_DB8A1001_1
(EPHRIN TYPE-A
RECEPTOR 2)		 5l6o EPHRIN TYPE-B
RECEPTOR 3
(Homo
sapiens) 		7 / 12 ILE A 639
ALA A 663
LYS A 665
ILE A 695
ILE A 709
THR A 711
LEU A 765
 6P6  A1001 (-4.0A)
6P6  A1001 (-3.3A)
None
None
6P6  A1001 ( 4.5A)
6P6  A1001 (-3.5A)
6P6  A1001 (-4.5A)
 0.53A 5i9xA-5l6oA:
36.4		 5i9xA-5l6oA:
68.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5I9Y_A_1N1A1001_1
(EPHRIN TYPE-A
RECEPTOR 2)		 5l6o EPHRIN TYPE-B
RECEPTOR 3
(Homo
sapiens) 		6 / 12 ILE A 639
ALA A 663
MET A 686
THR A 711
LEU A 765
SER A 775
 6P6  A1001 (-4.0A)
6P6  A1001 (-3.3A)
6P6  A1001 ( 4.2A)
6P6  A1001 (-3.5A)
6P6  A1001 (-4.5A)
6P6  A1001 ( 3.7A)
 0.64A 5i9yA-5l6oA:
35.7		 5i9yA-5l6oA:
68.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MO4_A_NILA601_1
(TYROSINE-PROTEIN
KINASE ABL1)		 5l6o EPHRIN TYPE-B
RECEPTOR 3
(Homo
sapiens) 		5 / 10 VAL A 647
LYS A 665
ILE A 709
PHE A 713
MET A 714
 None
None
6P6  A1001 ( 4.5A)
6P6  A1001 ( 4.5A)
None
 0.61A 5mo4A-5l6oA:
26.9		 5mo4A-5l6oA:
25.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5P9I_A_1E8A701_1
(TYROSINE-PROTEIN
KINASE BTK)		 5l6o EPHRIN TYPE-B
RECEPTOR 3
(Homo
sapiens) 		6 / 12 VAL A 647
ALA A 663
ILE A 709
THR A 711
LEU A 765
SER A 775
 None
6P6  A1001 (-3.3A)
6P6  A1001 ( 4.5A)
6P6  A1001 (-3.5A)
6P6  A1001 (-4.5A)
6P6  A1001 ( 3.7A)
 0.44A 5p9iA-5l6oA:
30.3		 5p9iA-5l6oA:
37.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BSD_A_1N1A901_0
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 5l6o EPHRIN TYPE-B
RECEPTOR 3
(Homo
sapiens) 		8 / 12 VAL A 647
ALA A 663
LYS A 665
MET A 686
ILE A 695
THR A 711
MET A 714
LEU A 765
 None
6P6  A1001 (-3.3A)
None
6P6  A1001 ( 4.2A)
None
6P6  A1001 (-3.5A)
None
6P6  A1001 (-4.5A)
 0.73A 6bsdA-5l6oA:
31.9		 6bsdA-5l6oA:
17.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6FNM_A_1N1A1001_1
(-)		 5l6o EPHRIN TYPE-B
RECEPTOR 3
(Homo
sapiens) 		7 / 12 ILE A 639
VAL A 647
ALA A 663
ILE A 709
THR A 711
MET A 714
LEU A 765
 6P6  A1001 (-4.0A)
None
6P6  A1001 (-3.3A)
6P6  A1001 ( 4.5A)
6P6  A1001 (-3.5A)
None
6P6  A1001 (-4.5A)
 0.53A 6fnmA-5l6oA:
37.5		 6fnmA-5l6oA:
86.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD4_A_STIA604_0
(TYROSINE-PROTEIN
KINASE ABL1)		 5l6o EPHRIN TYPE-B
RECEPTOR 3
(Homo
sapiens) 		7 / 12 VAL A 647
ALA A 663
LYS A 665
ILE A 709
THR A 711
LEU A 765
ASP A 776
 None
6P6  A1001 (-3.3A)
None
6P6  A1001 ( 4.5A)
6P6  A1001 (-3.5A)
6P6  A1001 (-4.5A)
None
 0.63A 6hd4A-5l6oA:
33.3		 6hd4A-5l6oA:
12.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD4_A_STIA604_0
(TYROSINE-PROTEIN
KINASE ABL1)		 5l6o EPHRIN TYPE-B
RECEPTOR 3
(Homo
sapiens) 		7 / 12 VAL A 647
ALA A 663
LYS A 665
MET A 686
ILE A 709
THR A 711
ASP A 776
 None
6P6  A1001 (-3.3A)
None
6P6  A1001 ( 4.2A)
6P6  A1001 ( 4.5A)
6P6  A1001 (-3.5A)
None
 0.67A 6hd4A-5l6oA:
33.3		 6hd4A-5l6oA:
12.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD4_B_STIB602_0
(TYROSINE-PROTEIN
KINASE ABL1)		 5l6o EPHRIN TYPE-B
RECEPTOR 3
(Homo
sapiens) 		7 / 12 VAL A 647
ALA A 663
LYS A 665
ILE A 694
ILE A 709
THR A 711
ASP A 776
 None
6P6  A1001 (-3.3A)
None
DIO  A1002 ( 4.5A)
6P6  A1001 ( 4.5A)
6P6  A1001 (-3.5A)
None
 1.49A 6hd4B-5l6oA:
33.0		 6hd4B-5l6oA:
12.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD4_B_STIB602_0
(TYROSINE-PROTEIN
KINASE ABL1)		 5l6o EPHRIN TYPE-B
RECEPTOR 3
(Homo
sapiens) 		8 / 12 VAL A 647
ALA A 663
LYS A 665
MET A 686
ILE A 709
THR A 711
LEU A 765
ASP A 776
 None
6P6  A1001 (-3.3A)
None
6P6  A1001 ( 4.2A)
6P6  A1001 ( 4.5A)
6P6  A1001 (-3.5A)
6P6  A1001 (-4.5A)
None
 0.74A 6hd4B-5l6oA:
33.0		 6hd4B-5l6oA:
12.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD6_A_STIA603_0
(TYROSINE-PROTEIN
KINASE ABL1)		 5l6o EPHRIN TYPE-B
RECEPTOR 3
(Homo
sapiens) 		9 / 12 VAL A 647
ALA A 663
LYS A 665
MET A 686
ILE A 709
THR A 711
PHE A 713
LEU A 765
ASP A 776
 None
6P6  A1001 (-3.3A)
None
6P6  A1001 ( 4.2A)
6P6  A1001 ( 4.5A)
6P6  A1001 (-3.5A)
6P6  A1001 ( 4.5A)
6P6  A1001 (-4.5A)
None
 0.74A 6hd6A-5l6oA:
33.2		 6hd6A-5l6oA:
12.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD6_B_STIB601_0
(TYROSINE-PROTEIN
KINASE ABL1)		 5l6o EPHRIN TYPE-B
RECEPTOR 3
(Homo
sapiens) 		8 / 12 VAL A 647
ALA A 663
LYS A 665
MET A 686
THR A 711
PHE A 713
LEU A 765
ASP A 776
 None
6P6  A1001 (-3.3A)
None
6P6  A1001 ( 4.2A)
6P6  A1001 (-3.5A)
6P6  A1001 ( 4.5A)
6P6  A1001 (-4.5A)
None
 0.76A 6hd6B-5l6oA:
32.9		 6hd6B-5l6oA:
12.93