SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6OT'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H42_C_VIAC903_2
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 5jzb 4,5:9,10-DISECO-3-HY
DROXY-5,9,17-TRIOXOA
NDROSTA-1(10),2-DIEN
E-4-OATE HYDROLASE
(Mycobacterium
tuberculosis) 		3 / 3 ASN A 169
ILE A 184
MET A 177
 None
None
6OT  A 301 ( 4.9A)
 0.82A 2h42C-5jzbA:
undetectable		 2h42C-5jzbA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_B_CLQB303_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 5jzb 4,5:9,10-DISECO-3-HY
DROXY-5,9,17-TRIOXOA
NDROSTA-1(10),2-DIEN
E-4-OATE HYDROLASE
(Mycobacterium
tuberculosis) 		5 / 11 HIS A  43
GLN A  73
GLY A 140
GLY A 141
MET A 222
 None
None
6OT  A 301 (-3.1A)
None
None
 1.34A 4fglA-5jzbA:
2.3
4fglB-5jzbA:
2.1		 4fglA-5jzbA:
21.55
4fglB-5jzbA:
21.55