SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6MO'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HAV_C_SRYC403_1
(AMINOGLYCOSIDE
PHOSPHOTRANSFERASE)		 3egw RESPIRATORY NITRATE
REDUCTASE 1 ALPHA
CHAIN
(Escherichia
coli) 		5 / 12 ASN A 545
ASP A 222
ASN A  52
SER A 719
ASN A1217
 None
6MO  A1247 (-2.1A)
MGD  A1246 ( 3.6A)
MD1  A1245 (-3.0A)
MD1  A1245 (-3.0A)
 1.27A 3havC-3egwA:
1.2		 3havC-3egwA:
12.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEN_A_5OGA804_1
(HDAC6 PROTEIN)		 3egw RESPIRATORY NITRATE
REDUCTASE 1 ALPHA
CHAIN
(Escherichia
coli) 		5 / 12 PRO A 190
SER A1099
HIS A1092
ASP A 222
GLY A 579
 MD1  A1245 (-4.5A)
MD1  A1245 (-2.7A)
MGD  A1246 ( 3.7A)
6MO  A1247 (-2.1A)
MGD  A1246 (-3.5A)
 1.32A 5eenA-3egwA:
3.5		 5eenA-3egwA:
15.00