SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6GU'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PWY_E_AC2E290_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3e9z PURINE-NUCLEOSIDE
PHOSPHORYLASE
(Schistosoma
mansoni) 		8 / 10 GLY A 120
GLU A 203
VAL A 219
GLY A 220
MET A 221
THR A 244
ASN A 245
HIS A 259
 6GU  A 704 (-2.9A)
6GU  A 704 (-2.4A)
6GU  A 704 ( 4.3A)
6GU  A 704 (-3.4A)
6GU  A 704 (-3.7A)
6GU  A 704 (-3.7A)
6GU  A 704 (-2.7A)
None
 0.61A 1pwyE-3e9zA:
41.0		 1pwyE-3e9zA:
48.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1V3Q_E_2DIE290_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3e9z PURINE-NUCLEOSIDE
PHOSPHORYLASE
(Schistosoma
mansoni) 		8 / 10 GLY A 120
GLU A 203
VAL A 219
GLY A 220
MET A 221
THR A 244
ASN A 245
HIS A 259
 6GU  A 704 (-2.9A)
6GU  A 704 (-2.4A)
6GU  A 704 ( 4.3A)
6GU  A 704 (-3.4A)
6GU  A 704 (-3.7A)
6GU  A 704 (-3.7A)
6GU  A 704 (-2.7A)
None
 0.51A 1v3qE-3e9zA:
41.2		 1v3qE-3e9zA:
48.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3E9R_A_ACTA700_0
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 3e9z PURINE-NUCLEOSIDE
PHOSPHORYLASE
(Schistosoma
mansoni) 		6 / 6 GLY A 120
TYR A 202
GLU A 203
GLY A 220
MET A 221
ASN A 245
 6GU  A 704 (-2.9A)
6GU  A 704 (-4.8A)
6GU  A 704 (-2.4A)
6GU  A 704 (-3.4A)
6GU  A 704 (-3.7A)
6GU  A 704 (-2.7A)
 0.28A 3e9rA-3e9zA:
48.5		 3e9rA-3e9zA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3E9R_C_ACTC700_0
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 3e9z PURINE-NUCLEOSIDE
PHOSPHORYLASE
(Schistosoma
mansoni) 		6 / 6 GLY A 120
TYR A 202
GLU A 203
GLY A 220
MET A 221
ASN A 245
 6GU  A 704 (-2.9A)
6GU  A 704 (-4.8A)
6GU  A 704 (-2.4A)
6GU  A 704 (-3.4A)
6GU  A 704 (-3.7A)
6GU  A 704 (-2.7A)
 0.32A 3e9rC-3e9zA:
48.2		 3e9rC-3e9zA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3F8W_A_ADNA300_1
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 3e9z PURINE-NUCLEOSIDE
PHOSPHORYLASE
(Schistosoma
mansoni) 		8 / 12 SER A  35
ALA A 118
GLY A 120
GLU A 203
VAL A 219
GLY A 220
ASN A 245
VAL A 262
 None
6GU  A 704 ( 3.5A)
6GU  A 704 (-2.9A)
6GU  A 704 (-2.4A)
6GU  A 704 ( 4.3A)
6GU  A 704 (-3.4A)
6GU  A 704 (-2.7A)
6GU  A 704 ( 4.3A)
 1.46A 3f8wA-3e9zA:
46.5		 3f8wA-3e9zA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3F8W_A_ADNA300_1
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 3e9z PURINE-NUCLEOSIDE
PHOSPHORYLASE
(Schistosoma
mansoni) 		11 / 12 TYR A  90
ALA A 118
GLY A 120
TYR A 202
GLU A 203
VAL A 219
GLY A 220
MET A 221
ASN A 245
HIS A 259
VAL A 262
 None
6GU  A 704 ( 3.5A)
6GU  A 704 (-2.9A)
6GU  A 704 (-4.8A)
6GU  A 704 (-2.4A)
6GU  A 704 ( 4.3A)
6GU  A 704 (-3.4A)
6GU  A 704 (-3.7A)
6GU  A 704 (-2.7A)
None
6GU  A 704 ( 4.3A)
 0.42A 3f8wA-3e9zA:
46.5		 3f8wA-3e9zA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3F8W_B_ADNB301_1
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 3e9z PURINE-NUCLEOSIDE
PHOSPHORYLASE
(Schistosoma
mansoni) 		11 / 12 HIS A  88
TYR A  90
GLY A 120
TYR A 202
GLU A 203
VAL A 219
GLY A 220
MET A 221
ASN A 245
HIS A 259
VAL A 262
 SO4  A 291 (-3.9A)
None
6GU  A 704 (-2.9A)
6GU  A 704 (-4.8A)
6GU  A 704 (-2.4A)
6GU  A 704 ( 4.3A)
6GU  A 704 (-3.4A)
6GU  A 704 (-3.7A)
6GU  A 704 (-2.7A)
None
6GU  A 704 ( 4.3A)
 0.42A 3f8wB-3e9zA:
46.0		 3f8wB-3e9zA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3F8W_B_ADNB301_1
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 3e9z PURINE-NUCLEOSIDE
PHOSPHORYLASE
(Schistosoma
mansoni) 		7 / 12 SER A  35
GLY A 120
GLU A 203
VAL A 219
GLY A 220
ASN A 245
VAL A 262
 None
6GU  A 704 (-2.9A)
6GU  A 704 (-2.4A)
6GU  A 704 ( 4.3A)
6GU  A 704 (-3.4A)
6GU  A 704 (-2.7A)
6GU  A 704 ( 4.3A)
 1.33A 3f8wB-3e9zA:
46.0		 3f8wB-3e9zA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3F8W_C_ADNC302_1
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 3e9z PURINE-NUCLEOSIDE
PHOSPHORYLASE
(Schistosoma
mansoni) 		11 / 12 HIS A  88
TYR A  90
ALA A 118
GLY A 120
TYR A 202
GLU A 203
VAL A 219
GLY A 220
MET A 221
ASN A 245
VAL A 262
 SO4  A 291 (-3.9A)
None
6GU  A 704 ( 3.5A)
6GU  A 704 (-2.9A)
6GU  A 704 (-4.8A)
6GU  A 704 (-2.4A)
6GU  A 704 ( 4.3A)
6GU  A 704 (-3.4A)
6GU  A 704 (-3.7A)
6GU  A 704 (-2.7A)
6GU  A 704 ( 4.3A)
 0.33A 3f8wC-3e9zA:
46.3		 3f8wC-3e9zA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3F8W_C_ADNC302_1
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 3e9z PURINE-NUCLEOSIDE
PHOSPHORYLASE
(Schistosoma
mansoni) 		8 / 12 SER A  35
ALA A 118
GLY A 120
GLU A 203
VAL A 219
GLY A 220
ASN A 245
VAL A 262
 None
6GU  A 704 ( 3.5A)
6GU  A 704 (-2.9A)
6GU  A 704 (-2.4A)
6GU  A 704 ( 4.3A)
6GU  A 704 (-3.4A)
6GU  A 704 (-2.7A)
6GU  A 704 ( 4.3A)
 1.46A 3f8wC-3e9zA:
46.3		 3f8wC-3e9zA:
100.00