SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6GB'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1TUV_A_VK3A4558_1 (PROTEIN YGIN)	4gpn	6-PHOSPHO-BETA-D-GLU COSIDASE (Streptococcus mutans)	4 / 7	TYR A 398 HIS A 402 LEU A 356 TYR A 313	None None None 6GB A 501 (-4.2A)	1.12A	1tuvA-4gpnA: undetectable	1tuvA-4gpnA: 11.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3GN8_A_DEXA247_2 (GLUCOCORTICOID RECEPTOR 2)	4gpn	6-PHOSPHO-BETA-D-GLU COSIDASE (Streptococcus mutans)	3 / 3	MET A 36 MET A 436 PHE A 131	None None 6GB A 501 ( 4.9A)	1.35A	3gn8A-4gpnA: undetectable	3gn8A-4gpnA: 18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LSK_B_ACTB901_0 (PYRANOSE 2-OXIDASE)	4gpn	6-PHOSPHO-BETA-D-GLU COSIDASE (Streptococcus mutans)	4 / 6	SER A 311 PHE A 131 HIS A 130 ASN A 175	None 6GB A 501 ( 4.9A) 6GB A 501 (-4.3A) 6GB A 501 (-3.6A)	1.30A	3lskB-4gpnA: undetectable	3lskB-4gpnA: 20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LSK_D_ACTD901_0 (PYRANOSE 2-OXIDASE)	4gpn	6-PHOSPHO-BETA-D-GLU COSIDASE (Streptococcus mutans)	4 / 6	SER A 311 PHE A 131 HIS A 130 ASN A 175	None 6GB A 501 ( 4.9A) 6GB A 501 (-4.3A) 6GB A 501 (-3.6A)	1.30A	3lskD-4gpnA: undetectable	3lskD-4gpnA: 20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6MN5_B_LLLB301_0 (AMINOGLYCOSIDE N(3)-ACETYLTRANSFERA SE, AAC(3)-IVA)	4gpn	6-PHOSPHO-BETA-D-GLU COSIDASE (Streptococcus mutans)	4 / 7	ARG A 263 TYR A 330 GLU A 332 GLU A 176	None None None 6GB A 501 (-3.0A)	1.23A	6mn5B-4gpnA: undetectable	6mn5B-4gpnA: 10.32

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1TUV_A_VK3A4558_1","PROTEIN YGIN","4gpn","6-PHOSPHO-BETA-D-GLUCOSIDASE","Streptococcus mutans",4,"TYR A 398;HIS A 402;LEU A 356;TYR A 313","None;None;None;6GB A 501 (-4.2A)","1.12A","1tuvA-4gpnA:undetectable",null],["3GN8_A_DEXA247_2","GLUCOCORTICOID RECEPTOR 2","4gpn","6-PHOSPHO-BETA-D-GLUCOSIDASE","Streptococcus mutans",3,"MET A  36;MET A 436;PHE A 131","None;None;6GB A 501 ( 4.9A)","1.35A","3gn8A-4gpnA:undetectable","1tuvA-4gpnA:11.13"],["3LSK_B_ACTB901_0","PYRANOSE 2-OXIDASE","4gpn","6-PHOSPHO-BETA-D-GLUCOSIDASE","Streptococcus mutans",4,"SER A 311;PHE A 131;HIS A 130;ASN A 175","None;6GB A 501 ( 4.9A);6GB A 501 (-4.3A);6GB A 501 (-3.6A)","1.30A","3lskB-4gpnA:undetectable","3gn8A-4gpnA:18.26"],["3LSK_D_ACTD901_0","PYRANOSE 2-OXIDASE","4gpn","6-PHOSPHO-BETA-D-GLUCOSIDASE","Streptococcus mutans",4,"SER A 311;PHE A 131;HIS A 130;ASN A 175","None;6GB A 501 ( 4.9A);6GB A 501 (-4.3A);6GB A 501 (-3.6A)","1.30A","3lskD-4gpnA:undetectable","3lskB-4gpnA:20.59"],["6MN5_B_LLLB301_0","AMINOGLYCOSIDE N(3)-ACETYLTRANSFERASE, AAC(3)-IVA","4gpn","6-PHOSPHO-BETA-D-GLUCOSIDASE","Streptococcus mutans",4,"ARG A 263;TYR A 330;GLU A 332;GLU A 176","None;None;None;6GB A 501 (-3.0A)","1.23A","6mn5B-4gpnA:undetectable","3lskD-4gpnA:20.59"]]